Gene

KWMTBOMO05974  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002809

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_9_[Amyelois_transitella]

Location

Bomo_Chr10(+):15667238-15667968      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 9      

Alternative Name

Mediator complex subunit 9

Location in the cell

Nuclear   Reliability : 3.69

CDS

ATGGAAAACAACACAGATCATTCAGAACAGACGAACTACAGTCCCCTGACTGTTGAGGATGTAGATGTAGACTTTTTACCGATTGTATACGATATAATACGAAGCGTGGAGAGAGATTTTCACGACAACGCGTCGAAAATACGCGAGTCCCACGAGTGCAGTCATAGAGTTCTTGAATTACAAAAGAGGCTAGAAATAGCTAAAGCTCAGATCAGGAGGCTCCCAGGTATAGAATTCAACAAACACGACCAGCTGAAGCAATTTGAACTGCTCCGCACTCAGCTGAGATTAAAGCGTGAACTCTTACAGAAGTATCGGAATATGTGCTCATTTGAGACATCATTCAAGTGA

Protein

MENNTDHSEQTNYSPLTVEDVDVDFLPIVYDIIRSVERDFHDNASKIRESHECSHRVLELQKRLEIAKAQIRRLPGIEFNKHDQLKQFELLRTQLRLKRELLQKYRNMCSFETSFK

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 9 family.

Keywords

Activator   Coiled coil   Complete proteome   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Mediator of RNA polymerase II transcription subunit 9

Uniprot

A0A2A4J9Q8   A0A1E1WCT5   S4PY63   A0A3S2MA80   A0A0L7KUP8   A0A194Q566   + More
A0A212FCG6   A0A194QWM2   A0A2H1VKY8   A0A1B6GE45   A0A1Y1LJU2   D6X1Y0   A0A087ZQ53   B4KNE7   A0A0M4ECP2   A0A310SLV7   A0A0L7RH89   A0A1W4XCH2   A0A0N1ITR0   A0A3B0JFH6   A0A154P2Z2   A0A0C9RBI2   B4J6U8   B4LKA9   Q71DE4   A0A0R1DS04   A0A0Q5VKV7   B4GC56   E2AT38   A0A1W4UKF7   A0A0J9RFP8   A0A1B2AJ79   A1ZB42   A0A0K8UNC1   A0A0K8VUE9   B3MBE7   A0A0J9RFT6   K7IRP0   Q290F0   A0A1A9WQP1   A0A0K8U1H4   A0A1B6EEB5   B4MIM6   A0A0J7KXA2   B4NSL4   B4HND3   A0A1A9UCW0   D3TM18   W8BTD0   A0A2J7Q8L1   A0A151JPI7   A0A151X1T1   F4W9Y7   A0A151JTV2   A0A158NTC5   A0A0C9R568   A0A034WIL2   A0A182NQ72   A0A026WCQ4   A0A182MD45   A0A182RKX1   A0A182WK11   A0A182XET8   A0A182UYN4   Q7Q9H8   A0A1I8Q8E9   J3JXC7   U5ESF5   B0XAF2   A0A151IPN3   A0A182YSU5   Q17PS7   A0A067RH52   A0A182P8U3   A0A182JGU3   A0A182HNW5   A0A182G7S9   A0A1I8MU43   A0A182T6W3   E2B9X2   A0A084WCN8   A0A182U3P8   A0A182Q3E6   A0A0V0G5A4   A0A2M3ZIM7   A0A2M4C407   A0A2M3ZAE4   A0A023F8N0   A0A182FCW5   A0A182K5N0   A0A162SX98   A0A0P5S391   A0A2M4ANV3   U4UKF6   N6U3Y4   A0A0P5SE55   A0A232EF83   A0A0P4VMF9   R4G847  

Pubmed

23622113    26227816    26354079    22118469    28004739    18362917    + More
19820115    17994087    14525923    17550304    20798317    22936249    10731132    12537572    12537569    20075255    15632085    20353571    24495485    21719571    21347285    25348373    24508170    30249741    12364791    14747013    17210077    22516182    25244985    17510324    24845553    26483478    25315136    24438588    25474469    23537049    28648823    27129103   

EMBL

NWSH01002488    PCG68190.1    GDQN01006289    JAT84765.1    GAIX01003838    JAA88722.1    + More
RSAL01000002    RVE54978.1    JTDY01005690    KOB66744.1    KQ459472    KPJ00145.1    AGBW02009199    OWR51408.1    KQ461175    KPJ07971.1    ODYU01003117    SOQ41466.1    GECZ01009061    JAS60708.1    GEZM01055233    JAV73078.1    KQ971371    EFA09949.2    CH933808    EDW08906.2    CP012524    ALC40576.1    KQ761155    OAD58179.1    KQ414592    KOC70230.1    KQ435756    KOX75944.1    OUUW01000001    SPP74070.1    KQ434809    KZC06241.1    GBYB01013864    JAG83631.1    CH916367    EDW02029.1    CH940648    EDW61700.2    AF531925    AAQ09824.1    CM000158    KRK00022.1    CH954179    KQS62071.1    CH479181    EDW32399.1    GL442489    EFN63392.1    CM002911    KMY94782.1    KX531396    ANY27206.1    AE013599    AY122154    BT001821    GDHF01024311    GDHF01018304    JAI28003.1    JAI34010.1    GDHF01010139    JAI42175.1    CH902619    EDV36072.1    KMY94781.1    CM000071    GDHF01031946    GDHF01029782    GDHF01013994    JAI20368.1    JAI22532.1    JAI38320.1    GEDC01001020    JAS36278.1    CH963719    EDW71965.1    LBMM01002353    KMQ94938.1    CH982320    EDX15592.1    CH480816    EDW48415.1    CCAG010005888    EZ422470    ADD18746.1    GAMC01010104    GAMC01010103    JAB96451.1    NEVH01016952    PNF24930.1    KQ978719    KYN29046.1    KQ982585    KYQ54180.1    GL888034    EGI68988.1    KQ981885    KYN33843.1    ADTU01025819    GBYB01003100    JAG72867.1    GAKP01004434    GAKP01004433    JAC54519.1    KK107263    QOIP01000011    EZA53855.1    RLU16984.1    AXCM01012095    AAAB01008900    EAA09311.4    BT127896    AEE62858.1    GANO01003270    JAB56601.1    DS232580    EDS43649.1    KQ976832    KYN07990.1    CH477189    EAT48764.1    KK852473    KDR23141.1    APCN01002799    JXUM01150904    JXUM01150905    JXUM01150906    KQ571107    KXJ68244.1    GL446605    EFN87559.1    ATLV01022798    KE525337    KFB47982.1    AXCN02001019    GECL01002897    JAP03227.1    GGFM01007622    MBW28373.1    GGFJ01010935    MBW60076.1    GGFM01004748    MBW25499.1    GBBI01000956    JAC17756.1    LRGB01000024    KZS21707.1    GDIQ01092966    JAL58760.1    GGFK01009134    MBW42455.1    KB632237    ERL90480.1    APGK01043586    KB741015    ENN75331.1    GDIQ01097014    JAL54712.1    NNAY01005096    OXU17007.1    GDKW01000264    JAI56331.1    ACPB03000491    ACPB03000492    GAHY01001602    JAA75908.1   

Proteomes

UP000218220    UP000283053    UP000037510    UP000053268    UP000007151    UP000053240    + More
UP000007266    UP000005203    UP000009192    UP000092553    UP000053825    UP000192223    UP000053105    UP000268350    UP000076502    UP000001070    UP000008792    UP000002282    UP000008711    UP000008744    UP000000311    UP000192221    UP000000803    UP000007801    UP000002358    UP000001819    UP000091820    UP000007798    UP000036403    UP000000304    UP000001292    UP000078200    UP000092444    UP000235965    UP000078492    UP000075809    UP000007755    UP000078541    UP000005205    UP000075884    UP000053097    UP000279307    UP000075883    UP000075900    UP000075920    UP000076407    UP000075903    UP000007062    UP000095300    UP000002320    UP000078542    UP000076408    UP000008820    UP000027135    UP000075885    UP000075880    UP000075840    UP000069940    UP000249989    UP000095301    UP000075901    UP000008237    UP000030765    UP000075902    UP000075886    UP000069272    UP000075881    UP000076858    UP000030742    UP000019118    UP000215335    UP000015103   

PRIDE

A1ZB42   

Pfam

PF07544   Med9        + More
PF18262   PhetRS_B1
PF03484   B5
PF03483   B3_4
PF10018   Med4
PF17759   tRNA_synthFbeta

Interpro

IPR039242   MED9_metazoa        + More
IPR037212   Med7/Med21-like       
IPR011425   Med9       
IPR009061   DNA-bd_dom_put_sf       
IPR020825   Phe-tRNA_synthase_B3/B4       
IPR041616   PheRS_beta_core       
IPR005146   B3/B4_tRNA-bd       
IPR005147   tRNA_synthase_B5-dom       
IPR040659   PhetRS_B1       
IPR004531   Phe-tRNA-synth_IIc_bsu_arc       
IPR019258   Mediator_Med4       

SUPFAM

SSF140718   SSF140718        + More
SSF46955   SSF46955       

Gene 3D

3.50.40.10    

CDD

cd00769  PheRS_beta_core

ProteinModelPortal

A0A2A4J9Q8   A0A1E1WCT5   S4PY63   A0A3S2MA80   A0A0L7KUP8   A0A194Q566   + More
A0A212FCG6   A0A194QWM2   A0A2H1VKY8   A0A1B6GE45   A0A1Y1LJU2   D6X1Y0   A0A087ZQ53   B4KNE7   A0A0M4ECP2   A0A310SLV7   A0A0L7RH89   A0A1W4XCH2   A0A0N1ITR0   A0A3B0JFH6   A0A154P2Z2   A0A0C9RBI2   B4J6U8   B4LKA9   Q71DE4   A0A0R1DS04   A0A0Q5VKV7   B4GC56   E2AT38   A0A1W4UKF7   A0A0J9RFP8   A0A1B2AJ79   A1ZB42   A0A0K8UNC1   A0A0K8VUE9   B3MBE7   A0A0J9RFT6   K7IRP0   Q290F0   A0A1A9WQP1   A0A0K8U1H4   A0A1B6EEB5   B4MIM6   A0A0J7KXA2   B4NSL4   B4HND3   A0A1A9UCW0   D3TM18   W8BTD0   A0A2J7Q8L1   A0A151JPI7   A0A151X1T1   F4W9Y7   A0A151JTV2   A0A158NTC5   A0A0C9R568   A0A034WIL2   A0A182NQ72   A0A026WCQ4   A0A182MD45   A0A182RKX1   A0A182WK11   A0A182XET8   A0A182UYN4   Q7Q9H8   A0A1I8Q8E9   J3JXC7   U5ESF5   B0XAF2   A0A151IPN3   A0A182YSU5   Q17PS7   A0A067RH52   A0A182P8U3   A0A182JGU3   A0A182HNW5   A0A182G7S9   A0A1I8MU43   A0A182T6W3   E2B9X2   A0A084WCN8   A0A182U3P8   A0A182Q3E6   A0A0V0G5A4   A0A2M3ZIM7   A0A2M4C407   A0A2M3ZAE4   A0A023F8N0   A0A182FCW5   A0A182K5N0   A0A162SX98   A0A0P5S391   A0A2M4ANV3   U4UKF6   N6U3Y4   A0A0P5SE55   A0A232EF83   A0A0P4VMF9   R4G847  

KEGG

101740037    K15149 mediator of RNA polymerase II transcription subunit 9 | (RefSeq) mediator of RNA polymerase I

GO

GO:0003712   GO:0006357   GO:0016592   GO:0005634   GO:0007406   GO:0006366   GO:0004826   GO:0005737   GO:0000287   GO:0006432   GO:0005524   GO:0003723   GO:0008026   GO:0004386   GO:0008270   GO:0006508   GO:0005622   GO:0007264   GO:0016597  

PANTHER

PTHR20844  

Subcellular location

Nucleus  

Length:

116

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00066

Exp number, first 60 AAs:

0.00066

Total prob of N-in:

0.44233

outside

1  -  116

 

 

Pi

11.878096

Theta

8.836801

Tajima's D

0.589554

CLR

0.855756

CSRT

0.553022348882556

Interpretation

Uncertain