SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05965  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA002901
Annotation
Liver_carboxylesterase_[Papilio_machaon]
Location
Bomo_Chr10(-):15579328-15591290      View in EpiBrowser
Location in the cell
PlasmaMembrane   Reliability : 1.117
 

Sequence

CDS
ATGCCTCATACTCTTCGTCTTCTGATGAGAGGTTCTTCAGCACCGCATCCATCAACAACGGGAGTCTCGTCACTCGCTGCATCGGTAGCACCAGGAACGAGTGGAGGGATAGACTCTGGCAAGCCGGGTGACTCTCTAGCCTGTGACCGAGTGATAAATATAGCTTTCTCTCGATCTGCGCACATTGCAAGTATGCTGCGATTGGTTGCTCTGTTAGGCTTGTTGTCGGCGGTGGCTGCCCGGTTGAAGTTAGACCCCCTTGTTGATACTCAGCGGGGACTCATCAGGGGACTGAGGTCCGAAAATGGAAAGTTCGCGAAGTTTTTGGGCATACCGTACGCACTAGTTGATGAGAACAATCCTTTCGGGCCATCAGTACCACACCCTGGTTTCGAAGAGACATTCGAAGCATACGATGATTCCGTAGTTTGTCCTCAAGTTACTAAGGGCGTCGGAGTTGGTAGTCTTCAGTGTTTGAACCTGAACGTTTATGTCCCAAACACGGCTACATCGCGCAACAAGCGCCCCGTGATGATTTGGATCCACGGAGGAGGCTTCGCCACCGGCAGTGGGACAGGCAGGGACTTCTCCTACGACGACCTGGTCCGACATGACGTCATCGTCGTATCGGTCAACTACCGACTCGGACCCTACGGGTTCTTATGCTTGGACAGTCCTGATATTCCCGGGAACCAGGGTTTGAAGGATCAAGCTCTTGCTCTCAGATGGATTAAGGAAAATATCGAAGCGTTCGGCGGAGATGTCTCTAAAATAACCTTGTTCGGAGAGAGTGCTGGTGGCGTCGCTGTCGAGCTACACCTACTGACCGACCAGGATAAACTGTTCAATCAGGTGATCATCCAGAGTGCATCTGCTTTCTTTGCTGGGGGTATTAGGAAACCTAGCAACCGTGTTCCAATAGAAATAGCAAACCAGCTGGGATTCGAAACTGACAACTTCGTAGAGGCGGTAAAGTTTCTGGCCGGTCAAGACCCCCACCTGGTGGTCGCAGCCAGCACTTCTCAAAGCTCTGCCATAAGAGGCGGTACTCTTAGACCTTGCCGAGAGAACAAATATGACGGAGTTGGCAATTTTCTTTCGGATTTTCCTGAAAATTTAAGGGCTAGAAACATTCCTGCTATTTATGGAGTAACCAATAAAGAATTTCTAACATTACATGCTTATGTGACCCCAGAAGATTACGAGGTGACAGGAATTCGAACTTTTCTGGAACGGGCTTTCAACTTGACCGATAGCGAGATGGAAGACCACGTGAGACATTTCTACATCGGAGACGAGACGCTGACCGAGAAGCAGTTCGATGAGTTTATAGATTTTGCATCGGACTATTACTTCAACTACGCCGTCCAGCGGTCTATAAAGAAGTCATTGGCTGACGGTAACAAGGAGGTATATTACTACGTGTTCTCGTACGACGGAGGCAGGAATGCCATGAAGCAGTACCTCGGCATAACGGCGGAGGGCGCTGCGCACGCGGACGAGCTCGGCTACCTGCTGGCCGTGGATGCGGTCCCGGGACAACACATCGCCGATGAGGACCAACTGATCATCGACAGGATCACTACTCTTTGGGCTAATTTTGCTAAATACGGAGTAGCCAGTGCATCCATGCATGCCTCATACTCTTCGTCTTCTGATGAGAGGTTCTTCAGCACCGCATCCATCAACAACGGGAGTCTCGTCACTCGCTGCATCGGTAGCATCAGGAACGAGTGGAGGGATAGACTCTGGCAAGCCGGTGCAAGTATGCTGCGATTGGTTGCTCTGTTAGGCTTGTTGTCGGCGGTGGCTGCCCGATTGAGGATAGACCCGCTGGTTGATACTCAGCGGGGACTCATCAGGGGACTGAGGTCTGAAAATGGAAAGTTCGCGAAGTTTTTGGGCATACCGTACGCACTAGTTGATGAGAACAATCCTTTCGGGCCATCAGTACCACACCCTGGATTCGAAGAGACATTCGAAGCGTACGATGATTCCGTAGTTTGTCCTCAAGTTACTAAGGGCGTCGGAGTTGGTAGTCTCCAGTGTTTAAACCTGAACGTTTATGTCCCAAACACGGCTACATCGCGCAACAAGCGCCCCGTGATGATTTGGATTCACGGAGGAAGCTTCGCCACCGGCAGTGGGACAGGCAGGGACTTCTCCTACGACGACCTGGTCCGACATGACGTCATCGTTGTATCGGTCAACTACCGACTCGGACCCTACGGGTTCTTATGCTTGGACAGTCCTGATATTCCCGGCAACCAGGGTTTGAAGGATCAAGCTCTTGCTCTCAGATGGATTAAGGAAAATATCGAAGCGTTCGGCGGAGATGTTTCTAAAATAACCTTATTCGGAGAGAGTGCTGGCGGCGTCGCTGTCGATCTACACTTACTGACCGACAAAGATGAACTGTTCAATCAGGTGATCATTCAGAGTGGATCTGCTTTCTTTGCTGGGGGTATTAGAAAACCTAACAACCGTGTTCCAATAGAAATAGCGAGCCAACTGGGATTCGAAACTGATAACTTCGCAGAGGCGATAAAGTTTCTGGTCGATCAAGACCCCCACCTGGTGGTCGCAGCTAGCACTTCTCAAAGATCTACCTTAGGAGGCAACACCCTCAGACCTTGCCTAGAGAACAAATACGACGGAGTTGACAGTTTTCTTTCCGACTTTCCTGAAAATTTAAGGGCTAGAAACATTCCTGCTATTTATGGAGTAAACAATAAAGAATTTCTTACATTACATGCTTTTGTGACCCCAGAAGATTACGAGGTGACAGGAATTCGAGCTTTTCTGGAACGGGCTTTCAACTTGACCGATAGCGAGATGGAAGACCACGTGAGACATTTCTACATCGGAGACGAGACGCTGACCGAGAAGTTTTTCGATGAGTTTATAGATTTTGCATCGGACTATTACTACAACTACGGCGTCCAGCGGTCTATTAAGAAGTCATTGGCTGACGGTAACAAGGAGGTATATTACTACGTGTTCTCGTACGACGGAGGCAGGAATGCCATGAAGCAGTACCTCGGCATAACGGCGGAGGGCGCTGCGCACGCGGACGAGCTCGGCTACCTGCTGGCCGTGGATGCGGTCCCGGGACAACACATCGCCGAGGAGGACCAACTGATCATCGACAGGATCACTACTCTTTGGGCTAATTTTGCTAAATACGGCAACCCCACCCCTGAGCCGACGGACCTGCTGCCGGTCGTGTGGACGACAGTAGAAGGTAACAAGCGGCCGTATCTGGACATCGACACCGACCTGCAGCTCAGAAGCAGGCCCTTCCACCACCGGATGGCCTTCTGGGATCTCTTCTATAAGCTCTATGGAGAATTGGAGCGCAGGAACTAG
Protein
MPHTLRLLMRGSSAPHPSTTGVSSLAASVAPGTSGGIDSGKPGDSLACDRVINIAFSRSAHIASMLRLVALLGLLSAVAARLKLDPLVDTQRGLIRGLRSENGKFAKFLGIPYALVDENNPFGPSVPHPGFEETFEAYDDSVVCPQVTKGVGVGSLQCLNLNVYVPNTATSRNKRPVMIWIHGGGFATGSGTGRDFSYDDLVRHDVIVVSVNYRLGPYGFLCLDSPDIPGNQGLKDQALALRWIKENIEAFGGDVSKITLFGESAGGVAVELHLLTDQDKLFNQVIIQSASAFFAGGIRKPSNRVPIEIANQLGFETDNFVEAVKFLAGQDPHLVVAASTSQSSAIRGGTLRPCRENKYDGVGNFLSDFPENLRARNIPAIYGVTNKEFLTLHAYVTPEDYEVTGIRTFLERAFNLTDSEMEDHVRHFYIGDETLTEKQFDEFIDFASDYYFNYAVQRSIKKSLADGNKEVYYYVFSYDGGRNAMKQYLGITAEGAAHADELGYLLAVDAVPGQHIADEDQLIIDRITTLWANFAKYGVASASMHASYSSSSDERFFSTASINNGSLVTRCIGSIRNEWRDRLWQAGASMLRLVALLGLLSAVAARLRIDPLVDTQRGLIRGLRSENGKFAKFLGIPYALVDENNPFGPSVPHPGFEETFEAYDDSVVCPQVTKGVGVGSLQCLNLNVYVPNTATSRNKRPVMIWIHGGSFATGSGTGRDFSYDDLVRHDVIVVSVNYRLGPYGFLCLDSPDIPGNQGLKDQALALRWIKENIEAFGGDVSKITLFGESAGGVAVDLHLLTDKDELFNQVIIQSGSAFFAGGIRKPNNRVPIEIASQLGFETDNFAEAIKFLVDQDPHLVVAASTSQRSTLGGNTLRPCLENKYDGVDSFLSDFPENLRARNIPAIYGVNNKEFLTLHAFVTPEDYEVTGIRAFLERAFNLTDSEMEDHVRHFYIGDETLTEKFFDEFIDFASDYYYNYGVQRSIKKSLADGNKEVYYYVFSYDGGRNAMKQYLGITAEGAAHADELGYLLAVDAVPGQHIAEEDQLIIDRITTLWANFAKYGNPTPEPTDLLPVVWTTVEGNKRPYLDIDTDLQLRSRPFHHRMAFWDLFYKLYGELERRN

Summary

Similarity
Belongs to the type-B carboxylesterase/lipase family.
Uniprot
A0A0L7L0K6   A0A1L8D6U2   A0A194Q3V9  
Pubmed
26227816    26354079   
EMBL
JTDY01003780    KOB69017.1    GEYN01000065    JAV02064.1    KQ459586    KPI98095.1    + More
Proteomes
UP000037510    UP000053268   
Pfam
PF00135   COesterase
Interpro
IPR002018   CarbesteraseB        + More
IPR019826   Carboxylesterase_B_AS       
IPR029058   AB_hydrolase       
SUPFAM
SSF53474   SSF53474       
Gene 3D
3.40.50.1820    
ProteinModelPortal
A0A0L7L0K6   A0A1L8D6U2   A0A194Q3V9  
PDB
6EMI     E-value=5.98564e-48,     Score=486

Ontologies

KEGG
101739057    no KO assigned | (RefSeq) juvenile hormone esterase-like
GO
GO:0016787   GO:0008152   GO:0015074   GO:0003676   GO:0004190   GO:0006508   GO:0005622   GO:0007264   GO:0008026   GO:0016597  

Topology

Length:
1122
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
2.23161000000002
Exp number, first 60 AAs:
0.12089
Total prob of N-in:
0.10598
outside
1  -  1122
 
 

Population Genetic Test Statistics

Pi
300.675655
Theta
174.535598
Tajima's D
2.394741
CLR
0.705703
CSRT
0.934853257337133
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 YGNPTPEPTDLLPVVWSTVEGNK 95.65 3e-10
28556443 YGNPTPEPTDLLPVVWSTVEGNK 95.65 3e-10
28556443 RPYLDIDTDLQLK 95.65 3e-10
28556443 YGNPTPEPTDLLPVVWSTVEGNK 95.65 3e-10
28556443 VPIEIASQLGFK 95.65 3e-10
28556443 VPIEIASQLGFK 95.65 3e-10
28556443 HFYIGDETLTEK 100.00 2e-04
28556443 AYVTPEDYEVTGIR 100.00 0.010
28556443 ENIEAFGGDVSK 100.00 0.010
28556443 LNVYVSNTATSR 100.00 0.010
28556443 YAPSIPK 100.00 0.010
28556443 RPYLDIDTDLQLR 100.00 0.017
28556443 RPYLDIDTDLQLR 100.00 0.017
28556443 NVYVPNTATSR 100.00 0.017
28556443 RPYLDIDTDLQLR 100.00 0.017
28556443 NIPAIYGVTNK 100.00 0.017
28556443 NIPAIYGVTNK 100.00 0.017
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