Gene

KWMTBOMO05931  Validated by peptides from experiments

Annotation

tetraspanin_E_[Bombyx_mori]

Location

Bomo_Chr10(+):14618685-14658920      View in EpiBrowser

Full name

Tetraspanin      

Location in the cell

PlasmaMembrane   Reliability : 4.566

CDS

ATGAACTGGACCATGGTCAAAGACTTACTGAAGACCCATCTTGCTGTCGGTCCGTGGATCTTCATAGTCGTCGGGGCTGTAATGTTCGTGATCGCGTTCTTGGGATGCTGTGGAGCGATACGCGAGAGTCACTGCATGGTCGTCACGTACGCAATCTTCTTGCTGGTGATCATCATTGTGCAAGTGGTGATTAGCGTCCTCCTCTTCACCTACGGCGAGAGCATCAAGGAGAGCATTATGGATGGCGTCGGCGTGTTATTCAAAAAGAGATCTGACGCTAACGCAGACGAGGCCGCCGAGGCTGTCTTCTCTGAATTGCAACGACAGTTCGAATGCTGCGGTAACACTGGCGCTATCAACTACGGCCAGTTCACGTTGCCCGAGTCCTGTTGCGTCAAGAAGAGCATCCTCTCTACCTTCGCCGGCAACAACTGCACGGTCGACGCCGCGAATCCCGGCTGCGGTCCCAAGATCGGCGAGCTCTACCAGAAATGGAACAAGCCTATAGCCGGCGTTGCTCTCGGTGTTGCTTGTGTTGAGGTGGTAGGAGCCCTGTTCGCGCTGTGCCTCGCCAATTCCATAAGAAACATGGACAGAAGGTCACGCTACTAA

Protein

MNWTMVKDLLKTHLAVGPWIFIVVGAVMFVIAFLGCCGAIRESHCMVVTYAIFLLVIIIVQVVISVLLFTYGESIKESIMDGVGVLFKKRSDANADEAAEAVFSELQRQFECCGNTGAINYGQFTLPESCCVKKSILSTFAGNNCTVDAANPGCGPKIGELYQKWNKPIAGVALGVACVEVVGALFALCLANSIRNMDRRSRY

Similarity

Belongs to the tetraspanin (TM4SF) family.

Feature

chain  Tetraspanin

Uniprot

Q2F647   Q2F648   A0A2A4IYD2   A0A194Q3K1   I4DJ82   I4DMY0   + More
S4PWL6   A0A212EWY8   A0A1E1W4P8   A0A2H1WW71   A0A1E1WV10   Q9NB08   A0A0L7KT54   A0A0L7L5Y5   A0A194QWJ9   S4PF79   A0A1E1W0A4   A0A194RHI5   A0A194QGK8   A0A182ME04   I4DPV3   H9JFI9   A0A232FLJ2   K7IST2   E9J9S4   A0A1S4G0M8   Q16HX5   A0A224XJR8   A0A182VNU8   A0A212EGN7   A0A182TSU7   A0A1S4G0S2   A0A2A4K899   Q16HX6   A0A182XLJ0   A0A067QYE5   Q7PTA7   B0WVX8   A0A026WT07   A0A224XJF0   A0A3L8DMA2   T1E2B6   A0A2M4CTQ4   A0A2M4CV63   Q1HQ39   A0A182YML0   A0A1L8DKH3   A0A023EK84   A0A2M4BYW8   A0A182FGC4   A0A0C9Q5P6   A0A084WER4   A0A182PP40   A0A182KQN6   A0A1Q3FLS8   A0A023EK90   A0A182I2Q6   A7URL1   A0A182K3B6   A0A182IP56   A0A2M4A0S0   A0A182Q6M3   A0A3S2LT60   W5JA30   A0A2M3ZEZ2   A0A2M3YY18   A0A2M4CHV5   T1DQT0   T1GTV8   V5I9N6   N6U6Y0   A0A154PEQ3   A0A2M4A0K4   A0A1L8DJJ6   D6WZB8   A0A1Q3EUG6   A0A2M4CQ62   R4V3T2   A0A0J7L311   A0A2J7QP49   A0A2H1WF85   A0A2H1WFM4   A0A0L7R0A6   A0A182N923   T1I6I6   A0A182R3J5   R4G434   U5EYJ6   B4J3W7   A0A1S3FQI1   E2A972   E2B227   A0A0N7Z8R2   B3NAJ4   W8BV43   B4QDU2   B4HQF4   A0A076KUR5   J9K093   R4UW62  

Pubmed

26354079    22651552    23622113    22118469    11122467    26227816    + More
19121390    28648823    20075255    21282665    17510324    24845553    12364791    14747013    17210077    24508170    30249741    24330624    25244985    24945155    24438588    20966253    20920257    23761445    23537049    18362917    19820115    17994087    20798317    27129103    24495485    22936249   

EMBL

DQ311225    ABD36170.1    DQ311224    ABD36169.1    NWSH01005565    PCG64123.1    + More
KQ459472    KPJ00118.1    AK401350    BAM17972.1    AK402648    BAM19270.1    GAIX01006573    JAA85987.1    AGBW02011867    OWR45999.1    GDQN01010381    GDQN01009120    JAT80673.1    JAT81934.1    ODYU01011526    SOQ57310.1    GDQN01000423    JAT90631.1    AF274023    AAF90149.1    JTDY01006162    KOB66231.1    JTDY01002812    KOB70674.1    KQ461175    KPJ07946.1    GAIX01004167    JAA88393.1    GDQN01010636    JAT80418.1    KQ460154    KPJ17288.1    KQ458880    KPJ04637.1    AXCM01015250    AK403798    BAM19943.1    BABH01002470    BABH01002471    BABH01002472    NNAY01000043    OXU31611.1    AAZX01003309    AAZX01016448    GL769399    EFZ10437.1    CH478132    EAT33856.1    GFTR01003691    JAW12735.1    AGBW02015051    OWR40653.1    NWSH01000032    PCG80495.1    EAT33857.1    KK853109    KDR11258.1    AAAB01008807    EAA04202.4    DS232134    EDS35810.1    KK107128    EZA58234.1    GFTR01003819    JAW12607.1    QOIP01000006    RLU21537.1    GALA01000879    JAA93973.1    GGFL01004539    MBW68717.1    GGFL01004540    MBW68718.1    DQ443213    ABF51302.1    GFDF01007244    JAV06840.1    GAPW01004057    JAC09541.1    GGFJ01009053    MBW58194.1    GBYB01009418    JAG79185.1    ATLV01023246    KE525341    KFB48708.1    GFDL01006609    JAV28436.1    GAPW01004058    JAC09540.1    APCN01000178    EDO64653.1    GGFK01001038    MBW34359.1    AXCN02000540    RSAL01000264    RVE43294.1    ADMH02002070    ETN59619.1    GGFM01006249    MBW27000.1    GGFM01000400    MBW21151.1    GGFL01000705    MBW64883.1    GAMD01000985    JAB00606.1    CAQQ02086791    CAQQ02086792    GALX01002620    JAB65846.1    APGK01047299    APGK01047300    KB741077    KB631602    ENN74342.1    ERL84575.1    KQ434889    KZC10345.1    GGFK01001025    MBW34346.1    GFDF01007446    JAV06638.1    KQ971372    EFA09730.1    GFDL01016103    JAV18942.1    GGFL01003304    MBW67482.1    KC571964    AGM32463.1    LBMM01001031    KMQ97046.1    NEVH01012097    PNF30360.1    ODYU01008291    SOQ51745.1    ODYU01008292    SOQ51746.1    KQ414672    KOC64231.1    ACPB03011594    ACPB03011595    GAHY01001690    JAA75820.1    GANO01000315    JAB59556.1    CH916367    EDW01550.1    GL437711    EFN70057.1    GL445031    EFN60283.1    GDKW01002635    JAI53960.1    CH954177    EDV59748.1    GAMC01009385    GAMC01009384    JAB97171.1    CM000362    CM002911    EDX05954.1    KMY91897.1    CH480816    EDW46693.1    KF433416    AII97740.1    ABLF02025726    ABLF02025730    ABLF02025731    KC571982    AGM32481.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000037510    UP000053240    UP000075883    + More
UP000005204    UP000215335    UP000002358    UP000008820    UP000075903    UP000075902    UP000076407    UP000027135    UP000007062    UP000002320    UP000053097    UP000279307    UP000076408    UP000069272    UP000030765    UP000075885    UP000075882    UP000075840    UP000075881    UP000075880    UP000075886    UP000283053    UP000000673    UP000015102    UP000019118    UP000030742    UP000076502    UP000007266    UP000036403    UP000235965    UP000053825    UP000075884    UP000015103    UP000075900    UP000001070    UP000081671    UP000000311    UP000008711    UP000000304    UP000001292    UP000007819   

PRIDE

Q2F647    Q2F648    H9JFI9    Q1HQ39   

Pfam

PF00335   Tetraspanin

Interpro

IPR008952   Tetraspanin_EC2_sf        + More
IPR018503   Tetraspanin_CS       
IPR018499   Tetraspanin/Peripherin       
IPR000301   Tetraspanin       
IPR036927   Cyt_c_oxase-like_su1_sf       
IPR042028   CD63_LEL       

SUPFAM

SSF48652   SSF48652        + More
SSF81442   SSF81442       

Gene 3D

1.10.1450.10    

CDD

cd03166  CD63_LEL

ProteinModelPortal

Q2F647   Q2F648   A0A2A4IYD2   A0A194Q3K1   I4DJ82   I4DMY0   + More
S4PWL6   A0A212EWY8   A0A1E1W4P8   A0A2H1WW71   A0A1E1WV10   Q9NB08   A0A0L7KT54   A0A0L7L5Y5   A0A194QWJ9   S4PF79   A0A1E1W0A4   A0A194RHI5   A0A194QGK8   A0A182ME04   I4DPV3   H9JFI9   A0A232FLJ2   K7IST2   E9J9S4   A0A1S4G0M8   Q16HX5   A0A224XJR8   A0A182VNU8   A0A212EGN7   A0A182TSU7   A0A1S4G0S2   A0A2A4K899   Q16HX6   A0A182XLJ0   A0A067QYE5   Q7PTA7   B0WVX8   A0A026WT07   A0A224XJF0   A0A3L8DMA2   T1E2B6   A0A2M4CTQ4   A0A2M4CV63   Q1HQ39   A0A182YML0   A0A1L8DKH3   A0A023EK84   A0A2M4BYW8   A0A182FGC4   A0A0C9Q5P6   A0A084WER4   A0A182PP40   A0A182KQN6   A0A1Q3FLS8   A0A023EK90   A0A182I2Q6   A7URL1   A0A182K3B6   A0A182IP56   A0A2M4A0S0   A0A182Q6M3   A0A3S2LT60   W5JA30   A0A2M3ZEZ2   A0A2M3YY18   A0A2M4CHV5   T1DQT0   T1GTV8   V5I9N6   N6U6Y0   A0A154PEQ3   A0A2M4A0K4   A0A1L8DJJ6   D6WZB8   A0A1Q3EUG6   A0A2M4CQ62   R4V3T2   A0A0J7L311   A0A2J7QP49   A0A2H1WF85   A0A2H1WFM4   A0A0L7R0A6   A0A182N923   T1I6I6   A0A182R3J5   R4G434   U5EYJ6   B4J3W7   A0A1S3FQI1   E2A972   E2B227   A0A0N7Z8R2   B3NAJ4   W8BV43   B4QDU2   B4HQF4   A0A076KUR5   J9K093   R4UW62  

PDB

5TCX     E-value=6.22621e-09,     Score=141

KEGG

692847    K06497 CD63 antigen | (RefSeq) tetraspanin E

PATHWAY

04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005887   GO:0031226   GO:0009986   GO:1901379   GO:0097487   GO:0002092   GO:0007160   GO:0005765   GO:0034613   GO:0035646   GO:0070062   GO:2001046   GO:1900746   GO:0032585   GO:0016477   GO:0031904   GO:0045169   GO:0016192   GO:0030117   GO:0005525   GO:0030131   GO:0005488   GO:0005622   GO:0007264   GO:0008026   GO:0016597  

Subcellular location

Membrane  

Length:

203

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

68.3625900000001

Exp number, first 60 AAs:

34.59575

Total prob of N-in:

0.00264

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  37

inside

38  -  49

TMhelix

50  -  72

outside

73  -  168

TMhelix

169  -  191

inside

192  -  203

 

 

Pi

207.13182

Theta

172.532797

Tajima's D

0.616034

CLR

1.214813

CSRT

0.546172691365432

Interpretation

Uncertain