Gene

KWMTBOMO05920

Pre Gene Modal

BGIBMGA002918

Annotation

uncharacterized_protein_Dvir_GJ17643_[Drosophila_virilis]

Location

Bomo_Chr10(-):14400836-14406395      View in EpiBrowser

Full name

Ubiquitin-conjugating enzyme E2-24 kDa      

Alternative Name

E2 ubiquitin-conjugating enzyme 2
Ubiquitin carrier protein
Ubiquitin-protein ligase

Location in the cell

Cytoplasmic   Reliability : 1.036

CDS

ATGTCAAAGGCTCTCGGCACATCGGCCAAGAGGATTCAAAAGGAATTGGCAGAAATTACATTGGACCCACCACCAAACTGCAGTGCAGGACCAAAAGGAGATAATTTGTATGAATGGGTGTCTACCATCCTTGGGCCACCAGGCTCAGTGTATGAAGGAGGAGTATTCTTCCTAGACATTCATTTTTCACCAGAATACCCGTTTAAGCCACCAAAGGTGACATTCCGAACAAGGATATATCATTGTAACATCAACAGTCAGGGAGTGATATGTTTAGACATCCTGAAAGACAACTGGTCTCCAGCTCTAACAATATCCAAAGTATTACTCTCAATATGTTCACTCCTAACTGACTGTAATCCAGCGGATCCTTTAGTTGGCAGTATTGCAACACAATATATACAGAATAGGGAAGAGCACGACCGCATCGCGCGCCTCTGGACAAAGCGTTACGCGACATGA

Protein

MSKALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYIQNREEHDRIARLWTKRYAT

Catalytic Activity

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.

Similarity

Belongs to the ubiquitin-conjugating enzyme family.

Keywords

ATP-binding   Complete proteome   Nucleotide-binding   Reference proteome   Transferase   Ubl conjugation pathway  

Feature

chain  Ubiquitin-conjugating enzyme E2-24 kDa

Uniprot

A0A1I8MP16   T1PIS3   B4LS79   A0A1A9WZX6   A0A1A9XZJ0   A0A1B0B921   + More
A0A1A9UMI3   A0A1I8Q2S4   B4JPT8   B4KKN2   A0A0L0BZL4   A0A1A9Z7S9   A0A0K8W0K3   W8CAN2   A0A0A1XG42   Q17BA8   B4MU55   A0A023EKC0   B4GT00   Q29KQ1   B4Q9T5   A0A3B0KDL4   A0A1W4W5K7   A0A034WVR8   A0A0J9R1A6   A0A0P8XX22   H9J083   A0A182UWL5   Q7PN26   A0A182HV56   B4HWV5   A0A182NEC1   W8BI86   A0A182JLT7   A0A2H1WWN5   Q541C3   P52485   A0A195C4A4   A0A0K8W8F6   B3N535   B4P115   B0W519   A0A182RVK6   A0A182W7U7   A0A1Q3FCU5   A0A212F0C0   A0A0L7QPP2   A0A2A3E835   A0A0J7KZA3   A0A088AJF4   E2BUA6   A0A0A1X723   A0A1E1WST8   A0A3S2TH38   A0A232EZ19   A0A195ELR3   E9J781   A0A195FQP7   A0A3L8DDH3   A0A026WT14   S4Q033   U5ERT8   A0A1B0G5Y9   E9G4D6   A0A1E1WIY3   A0A2M4BYN9   A0A1D2MHH0   A0A158NJL2   A0A1L8DTG4   A0A194QR10   A0A2M4ARU5   A0A2M4CPC8   A0A194Q433   A0A087ZI53   Q5MIQ4   A0A034WUJ3   E2A970   A0A0K8TKU8   R4WJH0   A0A0A1XI60   A0A1B6DFD4   A0A2M3ZBN3   A0A1B6HZN2   A0A2M4BXT8   A0A151XK03   D6X1Y6   F4WCE3   C0IRC5   A0A067QQ72   A0A0A9YBH8   A0A224XXN9   A0A0P4VR33   A0A023FB26   A0A069DWS7   R4G3L3   V5I9J6   A0A0T6AV55   A0A0P5QV12   A0A2M4BZ51   E0VTU2  

EC Number

2.3.2.23

Pubmed

25315136    17994087    26108605    24495485    25830018    17510324    + More
24945155    15632085    23185243    25348373    22936249    18057021    19121390    12364791    14747013    17210077    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    8576256    17550304    22118469    20798317    28648823    21282665    30249741    24508170    23622113    21292972    27289101    21347285    26354079    20920257    17244540    26369729    23691247    18362917    19820115    21719571    24845553    25401762    26823975    27129103    25474469    26334808    20566863   

EMBL

KA648005    AFP62634.1    CH940649    EDW64765.1    JXJN01010184    CH916372    + More
EDV98918.1    CH933807    EDW12696.1    JRES01001119    KNC25416.1    GDHF01007688    JAI44626.1    GAMC01005601    JAC00955.1    GBXI01004814    JAD09478.1    CH477324    EAT43538.1    CH963852    EDW75644.1    GAPW01004021    JAC09577.1    CH479189    EDW25509.1    CH379061    EAL33123.2    KRT04756.1    KRT04757.1    CM000361    EDX04602.1    OUUW01000006    SPP81748.1    GAKP01000652    JAC58300.1    CM002910    KMY89619.1    CH902620    KPU73929.1    KPU73930.1    BABH01019079    AAAB01008964    EAA12881.5    APCN01002494    CH480818    EDW52500.1    GAMC01005600    JAC00956.1    ODYU01011572    SOQ57397.1    AY094899    AE014134    AAM11252.1    AAN10762.1    AGB92897.1    AHN54328.1    X92663    KQ978292    KYM95450.1    GDHF01004952    GDHF01004661    JAI47362.1    JAI47653.1    CH954177    EDV58980.1    CM000157    EDW87990.1    KRJ97518.1    DS231840    EDS34585.1    GFDL01009668    JAV25377.1    AGBW02011105    OWR47198.1    KQ414821    KOC60446.1    KZ288349    PBC27442.1    LBMM01001682    KMQ95892.1    GL450619    EFN80734.1    GBXI01007606    JAD06686.1    GDQN01009715    GDQN01008430    GDQN01001286    GDQN01000945    JAT81339.1    JAT82624.1    JAT89768.1    JAT90109.1    RSAL01000147    RVE45864.1    NNAY01001516    OXU23726.1    KQ978739    KYN28819.1    GL768424    EFZ11321.1    KQ981305    KYN42793.1    QOIP01000009    RLU18212.1    KK107119    EZA58821.1    GAIX01000488    JAA92072.1    GANO01002684    JAB57187.1    CCAG010022414    GL732532    EFX85571.1    GDQN01011315    GDQN01010982    GDQN01010008    GDQN01004198    JAT79739.1    JAT80072.1    JAT81046.1    JAT86856.1    GGFJ01008900    MBW58041.1    LJIJ01001230    ODM92439.1    ADTU01001945    GFDF01004424    JAV09660.1    KQ461175    KPJ07932.1    GGFK01010131    MBW43452.1    GGFL01002863    MBW67041.1    KQ459472    KPJ00104.1    AY826156    AAV90728.1    GAKP01000653    JAC58299.1    GL437711    EFN70055.1    GDAI01002649    JAI14954.1    AK417685    BAN20900.1    GBXI01003645    JAD10647.1    GEDC01012887    GEDC01011469    JAS24411.1    JAS25829.1    GGFM01005172    MBW25923.1    GECU01027569    JAS80137.1    GGFJ01008754    MBW57895.1    KQ982052    KYQ60667.1    KQ971371    EFA09947.1    GL888070    EGI68123.1    EU492541    ACD13594.1    KK853603    KDR06369.1    GBHO01014633    GBRD01004916    GDHC01000264    JAG28971.1    JAG60905.1    JAQ18365.1    GFTR01003116    JAW13310.1    GDKW01001720    JAI54875.1    GBBI01000483    JAC18229.1    GBGD01003105    JAC85784.1    ACPB03005592    GAHY01001576    JAA75934.1    GALX01002820    JAB65646.1    LJIG01022738    KRT78970.1    GDIQ01109304    JAL42422.1    GGFJ01009224    MBW58365.1    DS235773    EEB16798.1   

Proteomes

UP000095301    UP000008792    UP000091820    UP000092443    UP000092460    UP000078200    + More
UP000095300    UP000001070    UP000009192    UP000037069    UP000092445    UP000008820    UP000007798    UP000008744    UP000001819    UP000000304    UP000268350    UP000192221    UP000007801    UP000005204    UP000075903    UP000007062    UP000075840    UP000001292    UP000075884    UP000075880    UP000000803    UP000078542    UP000008711    UP000002282    UP000002320    UP000075900    UP000075920    UP000007151    UP000053825    UP000242457    UP000036403    UP000005203    UP000008237    UP000283053    UP000215335    UP000078492    UP000078541    UP000279307    UP000053097    UP000092444    UP000000305    UP000094527    UP000005205    UP000053240    UP000053268    UP000000311    UP000075809    UP000007266    UP000007755    UP000027135    UP000015103    UP000009046   

PRIDE

H9J083    Q541C3    P52485   

Pfam

PF00179   UQ_con

Interpro

IPR000608   UBQ-conjugat_E2        + More
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR023313   UBQ-conjugating_AS       

SUPFAM

SSF54495   SSF54495       

Gene 3D

3.10.110.10    

CDD

cd00195  UBCc

ProteinModelPortal

A0A1I8MP16   T1PIS3   B4LS79   A0A1A9WZX6   A0A1A9XZJ0   A0A1B0B921   + More
A0A1A9UMI3   A0A1I8Q2S4   B4JPT8   B4KKN2   A0A0L0BZL4   A0A1A9Z7S9   A0A0K8W0K3   W8CAN2   A0A0A1XG42   Q17BA8   B4MU55   A0A023EKC0   B4GT00   Q29KQ1   B4Q9T5   A0A3B0KDL4   A0A1W4W5K7   A0A034WVR8   A0A0J9R1A6   A0A0P8XX22   H9J083   A0A182UWL5   Q7PN26   A0A182HV56   B4HWV5   A0A182NEC1   W8BI86   A0A182JLT7   A0A2H1WWN5   Q541C3   P52485   A0A195C4A4   A0A0K8W8F6   B3N535   B4P115   B0W519   A0A182RVK6   A0A182W7U7   A0A1Q3FCU5   A0A212F0C0   A0A0L7QPP2   A0A2A3E835   A0A0J7KZA3   A0A088AJF4   E2BUA6   A0A0A1X723   A0A1E1WST8   A0A3S2TH38   A0A232EZ19   A0A195ELR3   E9J781   A0A195FQP7   A0A3L8DDH3   A0A026WT14   S4Q033   U5ERT8   A0A1B0G5Y9   E9G4D6   A0A1E1WIY3   A0A2M4BYN9   A0A1D2MHH0   A0A158NJL2   A0A1L8DTG4   A0A194QR10   A0A2M4ARU5   A0A2M4CPC8   A0A194Q433   A0A087ZI53   Q5MIQ4   A0A034WUJ3   E2A970   A0A0K8TKU8   R4WJH0   A0A0A1XI60   A0A1B6DFD4   A0A2M3ZBN3   A0A1B6HZN2   A0A2M4BXT8   A0A151XK03   D6X1Y6   F4WCE3   C0IRC5   A0A067QQ72   A0A0A9YBH8   A0A224XXN9   A0A0P4VR33   A0A023FB26   A0A069DWS7   R4G3L3   V5I9J6   A0A0T6AV55   A0A0P5QV12   A0A2M4BZ51   E0VTU2  

PDB

3BZH     E-value=1.80966e-79,     Score=747

KEGG

101743337    K20217 ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23] | (RefSeq) ubiquitin-conjugating enzyme E2-24

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0016740   GO:0019915   GO:0004842   GO:0061631   GO:0000209   GO:0016021   GO:0016874  

Length:

153

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0913300000000001

Exp number, first 60 AAs:

0.08422

Total prob of N-in:

0.27920

outside

1  -  153

 

 

Pi

297.646851

Theta

227.987236

Tajima's D

0.219873

CLR

0.248476

CSRT

0.426228688565572

Interpretation

Uncertain