Gene

KWMTBOMO05913

Annotation

PREDICTED:_23_kDa_integral_membrane_protein-like_[Bombyx_mori]

Location

Bomo_Chr10(-):14303287-14314125      View in EpiBrowser

Full name

Tetraspanin      

Location in the cell

PlasmaMembrane   Reliability : 4.951

CDS

ATGATTACGACTATGTTTATTATAATATCCGGTTTGATGGTAGTGATGGGAATATCAGTCTACTCTCACTACCATAGTTTTTCGTTTTTCTACGAAAGCGCCAAGACTGGAAGGTTCTTAACTCCATCAGTGCTGTGCATTTTCTTGGGTCTTGCAATGTTCATAGTTTCCTTCTTTGGATTCTTCGGTAGTTTGAAACAGAGCACTTGCATGGTTAACTTGTACGCTTTCGTTCTCGCTTTGATCCTGCTAATAAAATTGACCATTGTGATTCTCGCTTTCACGATGGACACGAATCTAATCATGAAGTACGTGGACATCCCGGTGTGGGACTACGTAAATGATCCCGAGATTAGTGACGAAATTGACAGCCTACAGACTTCGCTCGGCTGCTGCGGAAGCAATTCCTATATGGATTATGTGGGAATGGAATTCACAGAGAAACACTCTACTGTCGTTGTGTCTAAAGAGGTTGACGGGGATCTGGTTACGTTGGTGATACCCAGTAGTTGCTGCGTCAGCAACGGCGATGCTTTCTGCACGAGGATGTACTCGACCAGTTGCAAAACTGCATTGGTCAATTTATTGGCGCAAAATGCAATCGTGATCGGTGTACTTGGCGTCTCGGTGATGTTTATTCAGTTACTGGGCATCGTATTCGCTCTACTTTTGGCACGTTGCATTCGTAAAATGAAAAGCGAGAGGGCGCTGATGGCTTGGAAGATTCGAGAACAAATGATAATGGCGCGAGCGGCAGAAGAATCAGCGAAAGATAATACATTAAACATCGGACACAATGAAATTAGTGTAGCATAA

Protein

MITTMFIIISGLMVVMGISVYSHYHSFSFFYESAKTGRFLTPSVLCIFLGLAMFIVSFFGFFGSLKQSTCMVNLYAFVLALILLIKLTIVILAFTMDTNLIMKYVDIPVWDYVNDPEISDEIDSLQTSLGCCGSNSYMDYVGMEFTEKHSTVVVSKEVDGDLVTLVIPSSCCVSNGDAFCTRMYSTSCKTALVNLLAQNAIVIGVLGVSVMFIQLLGIVFALLLARCIRKMKSERALMAWKIREQMIMARAAEESAKDNTLNIGHNEISVA

Similarity

Belongs to the tetraspanin (TM4SF) family.

Uniprot

A0A194Q521   A0A194QR05   A0A3S2NMI8   A0A1E1W056   A0A3G2CHU8   A0A3G2CHU0   + More
A0A2A4J588   A0A2A4ITT0   A0A2A4ITP8   A0A2H1WHE4   A0A1E1WLS7   S4NX85   A0A3S2PLD7   A0A194QQZ4   A0A194Q9L4   A0A2A4IVI7   A0A2A4J4A5   A0A212F0E7   A0A3S2KXX3   A0A2H1WHE8   A0A2J7QZJ0   H9J085   A0A151XJT2   A0A1B6KDN1   A0A2A3E8D0   A0A1B6MCQ8   A0A088AJF6   Q9NB09   J3JUM3   Q16LT3   A0A1B6HCW8   A0A1B6HHR4   A0A1Q3FKK5   A0A0A1X025   A0A1L8DJV1   A0A1L8DK41   A0A1L8DJK5   A0A023ENQ5   A0A1L8DKC0   A0A1B0D6J3   A0A023EMK4   A0A182IPX2   A0A023EPW8   A0A023ESE8   A0A1B6E2I7   A0A182H2Z1   A0A1B6GIS6   V9IM52   A0A0K8VE31   A0A0K8W976   A0A023EMJ0   B0W1E6   A0A232FCT9   B4M9P6   A0A1B6FPI6   A0A0K8TPC7   A0A034W8M1   B4Q7A9   W5J4K8   B4N099   B4HYS5   B4GJ35   Q29JV1   B4KEY5   D6X0E2   A0A158NJN4   A0A1B0B299   A0A1W4VMH2   B4NXJ4   Q9VLH0   A0A195B5J4   A0A1A9Y1P2   A0A1A9W2K0   B4JP51   A0A1I8PAW6   A0A3B0K795   A0A1L8EAQ7   F4WCE0   A0A182RK40   A0A1L8EF34   B3MM84   W8AVJ1   A0A067QFC7   A0A182WFF0   U5EP47   A0A3L8DCY1   A0A182LRX5   A0A0L7QP86   A0A1B0CUZ7   B3N7U7   A0A1Y1K6D0   A0A336LVF9   K7IWU1   C3UTC3   A0A195EKQ3   A0A154PIE1   H3BFF8   E9J782   A0A1B0AAL1  

Pubmed

26354079    23622113    22118469    19121390    11122467    22516182    + More
23537049    17510324    25830018    24945155    26483478    28648823    17994087    26369729    25348373    22936249    20920257    23761445    15632085    18362917    19820115    21347285    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    21719571    24495485    24845553    30249741    28004739    20075255    19364528    9215903    21282665   

EMBL

KQ459472    KPJ00100.1    KQ461175    KPJ07927.1    RSAL01000003    RVE54771.1    + More
GDQN01010732    GDQN01001235    JAT80322.1    JAT89819.1    MH514008    AYM54688.1    MH514007    AYM54687.1    NWSH01003126    PCG66906.1    NWSH01008489    PCG62543.1    PCG62542.1    ODYU01008695    SOQ52489.1    GDQN01003094    GDQN01001375    JAT87960.1    JAT89679.1    GAIX01012262    JAA80298.1    RVE54770.1    KPJ07928.1    KPJ00101.1    NWSH01007000    PCG63160.1    PCG66905.1    AGBW02011105    OWR47202.1    RSAL01000945    RVE41032.1    SOQ52488.1    NEVH01009069    PNF34006.1    BABH01019090    KQ982052    KYQ60664.1    GEBQ01030408    JAT09569.1    KZ288349    PBC27439.1    GEBQ01006270    JAT33707.1    AF274022    AAF90148.1    APGK01003084    APGK01003085    APGK01018485    APGK01018486    APGK01018487    BT126938    KB740076    KB735111    KB631643    AEE61900.1    ENN81658.1    ENN83444.1    ERL84920.1    CH477891    CH477347    EAT35294.1    EAT42969.1    GECU01035122    GECU01005586    JAS72584.1    JAT02121.1    GECU01033473    JAS74233.1    GFDL01007003    JAV28042.1    GBXI01011327    GBXI01009628    JAD02965.1    JAD04664.1    GFDF01007437    JAV06647.1    GFDF01007246    JAV06838.1    GFDF01007436    JAV06648.1    GAPW01003028    JAC10570.1    GFDF01007259    JAV06825.1    AJVK01003649    GAPW01003030    JAC10568.1    GAPW01003029    JAC10569.1    GAPW01001917    JAC11681.1    GEDC01031511    GEDC01024465    GEDC01019324    GEDC01018344    GEDC01005153    GEDC01000862    JAS05787.1    JAS12833.1    JAS17974.1    JAS18954.1    JAS32145.1    JAS36436.1    JXUM01106293    JXUM01106294    KQ565042    KXJ71418.1    GECZ01007431    JAS62338.1    JR052937    AEY61822.1    GDHF01015183    JAI37131.1    GDHF01006425    GDHF01004904    JAI45889.1    JAI47410.1    GAPW01003045    JAC10553.1    DS231821    EDS45016.1    NNAY01000426    OXU28495.1    CH940654    EDW57922.1    GECZ01017644    JAS52125.1    GDAI01001361    JAI16242.1    GAKP01007898    GAKP01007897    JAC51054.1    CM000361    CM002910    EDX04303.1    KMY89177.1    ADMH02002210    ETN57790.1    CH963920    EDW77512.1    CH480818    EDW52205.1    CH479184    EDW37349.1    CH379062    EAL32860.1    CH933807    EDW11954.1    KQ971372    EFA09586.1    ADTU01001951    JXJN01007521    CM000157    EDW88585.1    AE014134    AF274012    AY122216    AAF52720.1    AAF90138.1    AAM52728.1    KQ976582    KYM79783.1    CH916372    EDV99476.1    OUUW01000006    SPP81516.1    GFDG01002972    JAV15827.1    GL888070    EGI68120.1    GFDG01001477    JAV17322.1    CH902620    EDV31844.2    GAMC01017840    GAMC01017837    JAB88718.1    KK853603    KDR06365.1    GANO01000316    JAB59555.1    QOIP01000009    RLU18214.1    AXCM01001804    KQ414821    KOC60442.1    AJWK01029905    AJWK01029906    CH954177    EDV58308.1    GEZM01091224    GEZM01091222    JAV57012.1    UFQT01000215    SSX21810.1    AAZX01000576    FJ654711    ACP18832.1    KQ978739    KYN28818.1    KQ434924    KZC11625.1    AFYH01022117    GL768424    EFZ11326.1   

Proteomes

UP000053268    UP000053240    UP000283053    UP000218220    UP000007151    UP000235965    + More
UP000005204    UP000075809    UP000242457    UP000005203    UP000019118    UP000030742    UP000008820    UP000092462    UP000075880    UP000069940    UP000249989    UP000002320    UP000215335    UP000008792    UP000000304    UP000000673    UP000007798    UP000001292    UP000008744    UP000001819    UP000009192    UP000007266    UP000005205    UP000092460    UP000192221    UP000002282    UP000000803    UP000078540    UP000092443    UP000091820    UP000001070    UP000095300    UP000268350    UP000007755    UP000075900    UP000007801    UP000027135    UP000075920    UP000279307    UP000075883    UP000053825    UP000092461    UP000008711    UP000002358    UP000078492    UP000076502    UP000008672    UP000092445   

PRIDE

H9J085    Q9VLH0   

Pfam

PF00335   Tetraspanin        + More
PF04218   CENP-B_N
PF14698   ASL_C2
PF00206   Lyase_1

Interpro

IPR018499   Tetraspanin/Peripherin        + More
IPR000301   Tetraspanin       
IPR008952   Tetraspanin_EC2_sf       
IPR018503   Tetraspanin_CS       
IPR007889   HTH_Psq       
IPR009057   Homeobox-like_sf       
IPR000048   IQ_motif_EF-hand-BS       
IPR009049   Argininosuccinate_lyase       
IPR022761   Fumarate_lyase_N       
IPR020557   Fumarate_lyase_CS       
IPR000362   Fumarate_lyase_fam       
IPR024083   Fumarase/histidase_N       
IPR029419   Arg_succ_lyase_C       
IPR008948   L-Aspartase-like       

SUPFAM

SSF48652   SSF48652        + More
SSF46689   SSF46689       
SSF48557   SSF48557       

Gene 3D

1.10.1450.10     1.10.275.10    

CDD

cd01359  Argininosuccinate_lyase

ProteinModelPortal

A0A194Q521   A0A194QR05   A0A3S2NMI8   A0A1E1W056   A0A3G2CHU8   A0A3G2CHU0   + More
A0A2A4J588   A0A2A4ITT0   A0A2A4ITP8   A0A2H1WHE4   A0A1E1WLS7   S4NX85   A0A3S2PLD7   A0A194QQZ4   A0A194Q9L4   A0A2A4IVI7   A0A2A4J4A5   A0A212F0E7   A0A3S2KXX3   A0A2H1WHE8   A0A2J7QZJ0   H9J085   A0A151XJT2   A0A1B6KDN1   A0A2A3E8D0   A0A1B6MCQ8   A0A088AJF6   Q9NB09   J3JUM3   Q16LT3   A0A1B6HCW8   A0A1B6HHR4   A0A1Q3FKK5   A0A0A1X025   A0A1L8DJV1   A0A1L8DK41   A0A1L8DJK5   A0A023ENQ5   A0A1L8DKC0   A0A1B0D6J3   A0A023EMK4   A0A182IPX2   A0A023EPW8   A0A023ESE8   A0A1B6E2I7   A0A182H2Z1   A0A1B6GIS6   V9IM52   A0A0K8VE31   A0A0K8W976   A0A023EMJ0   B0W1E6   A0A232FCT9   B4M9P6   A0A1B6FPI6   A0A0K8TPC7   A0A034W8M1   B4Q7A9   W5J4K8   B4N099   B4HYS5   B4GJ35   Q29JV1   B4KEY5   D6X0E2   A0A158NJN4   A0A1B0B299   A0A1W4VMH2   B4NXJ4   Q9VLH0   A0A195B5J4   A0A1A9Y1P2   A0A1A9W2K0   B4JP51   A0A1I8PAW6   A0A3B0K795   A0A1L8EAQ7   F4WCE0   A0A182RK40   A0A1L8EF34   B3MM84   W8AVJ1   A0A067QFC7   A0A182WFF0   U5EP47   A0A3L8DCY1   A0A182LRX5   A0A0L7QP86   A0A1B0CUZ7   B3N7U7   A0A1Y1K6D0   A0A336LVF9   K7IWU1   C3UTC3   A0A195EKQ3   A0A154PIE1   H3BFF8   E9J782   A0A1B0AAL1  

PDB

5TCX     E-value=0.0900706,     Score=81

KEGG

101736115    no KO assigned | (RefSeq) 23 kDa integral membrane protein-like

GO

GO:0016021   GO:0003677   GO:0005887   GO:0008168   GO:0004056   GO:0042450   GO:0005515   GO:0005488   GO:0016765   GO:0005634   GO:0006355   GO:0016818   GO:0003676   GO:0008026   GO:0016597  

PANTHER

PTHR43814  

Subcellular location

Membrane  

Length:

271

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

90.10589

Exp number, first 60 AAs:

42.30299

Total prob of N-in:

0.98981

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  24

outside

25  -  38

TMhelix

39  -  61

inside

62  -  73

TMhelix

74  -  96

outside

97  -  200

TMhelix

201  -  223

inside

224  -  271

 

 

Pi

202.501679

Theta

158.274809

Tajima's D

0.823313

CLR

0.485416

CSRT

0.605019749012549

Interpretation

Uncertain