Gene

KWMTBOMO05904

Pre Gene Modal

BGIBMGA002922

Annotation

ATP_dependent_transmembrane_transporter_protein_[Bombyx_mori]

Location

Bomo_Chr10(-):14143763-14146195      View in EpiBrowser

Full name

Protein white      

Location in the cell

PlasmaMembrane   Reliability : 3.933

CDS

ATGAGAGAGAAACGCGCGATCAGTACGAGGCTTTGTGGCGGACTGCCGGCGCAGCAGCCCGGCGTCACCTGCGATAACGCGGCCGCGCGTTGGCTCCTGATTGGCGCGCGCACGCATCACCTGATTCTTGCGCGCAGGTCCGTCCCACCGTACTTAAGTTGGATATCGTATCTATCCTGGTTCCACTACGGCAACGAAGCGCTTCTCATCAACCAGTGGGCCGGCGTGGAGACTATCGCCTGCACAAGGGAGAACTTCACCTGTCCAGCTTCGGGACAGGTCGTACTGGAGACGCTTAGCTTTTCACAGGACGATTTCGCGATGGACGTGGTGAACATGATCTTGTTATTCGTCGGCTTCAGATTTCTGGCGTACCTCGCCCTGCTGTGGAGGACGCGCAGGGCCAAGTGA

Protein

MREKRAISTRLCGGLPAQQPGVTCDNAAARWLLIGARTHHLILARRSVPPYLSWISYLSWFHYGNEALLINQWAGVETIACTRENFTCPASGQVVLETLSFSQDDFAMDVVNMILLFVGFRFLAYLALLWRTRRAK

Description

Part of a membrane-spanning permease system necessary for the transport of pigment precursors into pigment cells responsible for eye color. White dimerize with brown for the transport of guanine. Scarlet and white complex transports a metabolic intermediate (such as 3-hydroxy kynurenine) from the cytoplasm into the pigment granules.

Subunit

Heterodimer of white with either brown or scarlet.

Similarity

Belongs to the PI3/PI4-kinase family.
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.

Keywords

ATP-binding   Complete proteome   Membrane   Nucleotide-binding   Pigment   Reference proteome   Transmembrane   Transmembrane helix   Transport   Glycoprotein  

Feature

chain  Protein white

Uniprot

Q9NH94   H9J087   B7XCV5   B3GQX5   A0A212F0E3   A0A0C5PTD7   + More
A0A194Q3I4   A0A194QRF1   A0A3R5WTC8   T1GGV8   A0A026WBC3   A0A3L8DP96   F4WVN8   A0A195D4B1   A0A151XF99   B4GYI5   A0A195FWS3   A0A158NHH2   A0A195AUR0   A0A2Z5ZBX4   A0A195E2Y4   A0A0L7QVP7   A0A0C9PHK2   A0A1B0CB12   A0A0C9QIB5   A0A0Q9W770   B4MG61   A0A0M4ETI1   A0A2S0X9Z2   A0A232FDM6   B4R3U7   Q60FC5   A0A158V6Z1   A0A1W4VF76   A0A1B0YWI7   B4L879   A0A3B0KIY5   A0A3B0KPD8   A0A0M9A9I2   B5DLT3   A0A0R3NZL1   P10090   B3NTX4   B3MWF6   A0A0R1EA29   A8E1U1   B4Q0V6   Q2LD54   A0A346A6M2   Q94960   Q8IS30   B4JJE3   W8AX98   A0A034VCM1   Q17320   A0A0K8VYU6   O77423   A0A0K8W6U9   B4NDV8   A0A1I8P5B8   Q8WRR1   Q8WRF2   A0A067RAU0   Q9BH97   E2C2K3   A0A1I8MED8   T1PA82   A0A087ZW42   A0A1A9W968   A0A1B0G2T2   A0A1A9XVI0   A0A1B0B3W9   A0A1A9V0K8   A0A1B0A8G3   A0A0J7KSS0  

Pubmed

11016828    19121390    18996197    22118469    25636859    26354079    + More
24508170    30249741    21719571    17994087    21347285    29654886    28648823    15705502    15632085    2109311    6084717    11156992    10731132    12537572    10731137    2503416    11294610    17550304    15972463    29187976    8601488    8889526    25830018    24495485    25348373    8533095    9359576    18362917    19820115    24845553    11238408    20798317    25315136   

EMBL

AF229609    AAF61569.1    BABH01019098    BABH01019099    BABH01019100    BABH01019101    + More
BABH01019102    BABH01019103    BABH01019104    BABH01019105    AB445460    BAH03523.1    EU722903    ACD99701.1    AGBW02011105    OWR47210.1    KM667971    AJQ21779.1    KQ459472    KPJ00092.1    KQ461175    KPJ07919.1    MH172526    QAA95933.1    CAQQ02175586    CAQQ02175587    KK107293    EZA53360.1    QOIP01000005    RLU22270.1    GL888393    EGI61708.1    KQ976870    KYN07740.1    KQ982194    KYQ59053.1    CH479197    EDW27841.1    KQ981208    KYN44888.1    ADTU01015824    KQ976737    KYM75916.1    LC368084    BBC77943.1    KQ979763    KYN19244.1    KQ414727    KOC62606.1    GBYB01000323    JAG70090.1    AJWK01004725    AJWK01004726    AJWK01004727    AJWK01004728    GBYB01000322    JAG70089.1    CH940672    KRF77745.1    EDW57384.1    CP012528    ALC48197.1    MH105806    AWC08636.1    NNAY01000361    OXU28894.1    CM000366    EDX16959.1    AB191788    BAD54748.1    KF828804    AIN44121.1    KU376474    ANO53447.1    CH933814    EDW05654.1    OUUW01000015    SPP88490.1    SPP88489.1    KQ435713    KOX79246.1    CH379064    EDY72595.1    KRT06475.1    X51749    X02974    AB028139    AE014298    AL133506    X76202    CH954180    EDV45682.1    CH902625    EDV34941.1    CM000162    KRK06073.1    AM887687    CAP09074.1    EDX01323.1    DQ335250    ABC69732.1    MF908522    AXK92644.1    U64875    AAB06578.1    AH012033    GBXI01016111    AAN38825.1    JAC98180.1    CH916370    EDV99695.1    GAMC01015788    JAB90767.1    GAKP01017893    GAKP01017891    JAC41061.1    X89933    GDHF01008584    JAI43730.1    U97104    AAC61893.1    GDHF01033402    GDHF01005555    JAI18912.1    JAI46759.1    CH964239    EDW81927.1    AF422804    AAL56571.1    AH011253    AF442746    KQ971372    AAL40947.1    EFA09849.1    KK852575    KDR20987.1    AF318275    AF318276    AAK21872.1    GL452135    EFN77859.1    KA645686    AFP60315.1    CCAG010008024    JXJN01008099    LBMM01003652    KMQ93279.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000015102    UP000053097    + More
UP000279307    UP000007755    UP000078542    UP000075809    UP000008744    UP000078541    UP000005205    UP000078540    UP000078492    UP000053825    UP000092461    UP000008792    UP000092553    UP000215335    UP000000304    UP000192221    UP000009192    UP000268350    UP000053105    UP000001819    UP000000803    UP000008711    UP000007801    UP000002282    UP000001070    UP000007798    UP000095300    UP000007266    UP000027135    UP000008237    UP000095301    UP000005203    UP000091820    UP000092444    UP000092443    UP000092460    UP000078200    UP000092445    UP000036403   

PRIDE

Q9NH94    H9J087    B7XCV5    B3GQX5    P10090    Q17320    + More

Pfam

PF01061   ABC2_membrane        + More
PF00005   ABC_tran
PF00613   PI3Ka
PF00454   PI3_PI4_kinase
PF00794   PI3K_rbd
PF00792   PI3K_C2
PF02192   PI3K_p85B
PF13193   AMP-binding_C

Interpro

IPR027417   P-loop_NTPase        + More
IPR003439   ABC_transporter-like       
IPR017871   ABC_transporter_CS       
IPR013525   ABC_2_trans       
IPR005284   Pigment_permease/Abcg       
IPR003593   AAA+_ATPase       
IPR000341   PI3K_Ras-bd_dom       
IPR042236   PI3K_accessory_sf       
IPR002420   PI3K_C2_dom       
IPR011009   Kinase-like_dom_sf       
IPR000403   PI3/4_kinase_cat_dom       
IPR018936   PI3/4_kinase_CS       
IPR003113   PI3K_adapt-bd_dom       
IPR029071   Ubiquitin-like_domsf       
IPR036940   PI3/4_kinase_cat_sf       
IPR015433   PI_Kinase       
IPR016024   ARM-type_fold       
IPR035892   C2_domain_sf       
IPR001263   PI3K_accessory_dom       
IPR025110   AMP-bd_C       

SUPFAM

SSF52540   SSF52540        + More
SSF54236   SSF54236       
SSF48371   SSF48371       
SSF56112   SSF56112       

Gene 3D

1.10.1070.11     1.25.40.70     2.60.40.150    

ProteinModelPortal

Q9NH94   H9J087   B7XCV5   B3GQX5   A0A212F0E3   A0A0C5PTD7   + More
A0A194Q3I4   A0A194QRF1   A0A3R5WTC8   T1GGV8   A0A026WBC3   A0A3L8DP96   F4WVN8   A0A195D4B1   A0A151XF99   B4GYI5   A0A195FWS3   A0A158NHH2   A0A195AUR0   A0A2Z5ZBX4   A0A195E2Y4   A0A0L7QVP7   A0A0C9PHK2   A0A1B0CB12   A0A0C9QIB5   A0A0Q9W770   B4MG61   A0A0M4ETI1   A0A2S0X9Z2   A0A232FDM6   B4R3U7   Q60FC5   A0A158V6Z1   A0A1W4VF76   A0A1B0YWI7   B4L879   A0A3B0KIY5   A0A3B0KPD8   A0A0M9A9I2   B5DLT3   A0A0R3NZL1   P10090   B3NTX4   B3MWF6   A0A0R1EA29   A8E1U1   B4Q0V6   Q2LD54   A0A346A6M2   Q94960   Q8IS30   B4JJE3   W8AX98   A0A034VCM1   Q17320   A0A0K8VYU6   O77423   A0A0K8W6U9   B4NDV8   A0A1I8P5B8   Q8WRR1   Q8WRF2   A0A067RAU0   Q9BH97   E2C2K3   A0A1I8MED8   T1PA82   A0A087ZW42   A0A1A9W968   A0A1B0G2T2   A0A1A9XVI0   A0A1B0B3W9   A0A1A9V0K8   A0A1B0A8G3   A0A0J7KSS0  

KEGG

692586    K21396 ATP-binding cassette, subfamily G (WHITE), eye pigment precursor transporter | (RefSeq) wh3,

GO

GO:0005524   GO:0055085   GO:0016021   GO:0016887   GO:0046854   GO:0016301   GO:0048015   GO:0008558   GO:1905948   GO:0007613   GO:0015842   GO:0042401   GO:0051615   GO:0031410   GO:0005275   GO:0008049   GO:0048072   GO:0042441   GO:0005395   GO:0070731   GO:0042332   GO:0098793   GO:0031409   GO:0006727   GO:0006856   GO:0090740   GO:0048770   GO:0042626   GO:0005886  

PANTHER

PTHR10048  

Subcellular location

Membrane  
Cytoplasmic granule membrane  

Length:

136

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

35.88819

Exp number, first 60 AAs:

10.5983

Total prob of N-in:

0.79650

POSSIBLE N-term signal

sequence

outside

1  -  107

TMhelix

108  -  130

inside

131  -  136

 

 

Pi

239.316235

Theta

178.562763

Tajima's D

0.911509

CLR

0

CSRT

0.633168341582921

Interpretation

Uncertain