Gene

KWMTBOMO05903  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002924

Annotation

scarlet_[Bombyx_mori]

Location

Bomo_Chr10(-):14087186-14120785      View in EpiBrowser

Full name

Protein scarlet      

Location in the cell

PlasmaMembrane   Reliability : 4.747

CDS

ATGGGTAAAAAAGCTGATACGACAAAGAGGAGCGCCGATAACAGCCCTGAAAAGAGTGAAAGCCCTCAACCTTTGCAGAGTACTTCATATGAGCTGTTGCCTGCAGACTTAGTCTATATAGACAGCGGCATCAAGACCAGCCCCGTCAAGTATGACTCGTTATACCCTGAAGTGGAGGAGGTGTTCGGAGTCCCACGTTCGCCTCGACCCTGCACCCTCGTGTGGAGGGATGTGACAGTGCACGTGAAACTGAAAAATGGAAGATTGAAACGACTAGTTAATAATGTGAGCGGCATAGCGAAACCTGGCACTCTTATTGCTTTGATGGGACCTAGCGGTGCTGGAAAAACTACGCTCATGTCTGCATTAGCCCATCGAAGCCCATTCGGAACAGTGATAGACGGCGAAATCATCATGAACGGTCGTCCAGTCTGCAGCTACGTGGACAGAGAAAGCGGCTACATGCATCAAGACGACATCTTCGCTGAAAACCTAACAGTTATCGAGCATCTAACGGTCATGGCTCGTCTACGCATGGATAGACGCACATCAACTGTAGCCAGGAAACGCCGGGTGAATCAGTTGATGAGGCAGTTGTCTCTCTACGAGTCTAGATTCACGAGGATAGGAGGCCTCGATGGACATAAGACCTTGTCTGGTGGAGAAAGGAAAAGGCTGGCTTTCGCTACTGAATTACTAACGGATCCGGGGCTTCTGTTTTGCGACGAGCCCACCACAGGATTAGACTCCTCGTCAGCGCTGAAGCTAGTATCACTCCTCCGAGCCAGTGCAGCCCAGGGAAAGACCGTGATATGCACTATACACCAGCCCTCCTCAGAACTGATGGCACATTTCGACAAGCTAGTCTTGTTAGCTGAAGGAAGGATCGCCTTTGCGGGAAACGCATCTGCTGCTTTGGGATTTTTCGAAAGTCTCGGCTACCACTGTCCCTTAACGTACAACCCGACGGATTACTTCATAAAAGTGTTGGCTTTAACTCCTGGCTCCGAAGCTGCGTCACGTCACGCTATCAAGAGTATATGCGACCGGTTTGCCGTCAGCGATGTCGCTAAGGAACTGGACATGGAGATTCATTTGGAGTATCATCTTATGGATAATGAGGTGGAGGACTCAAGGAGGTTAAGAGGTGACAGCTTTAGGCCACCACATTTCTACACGAAGATAATGTGGCTCGTGTACAGATACCTGCTGATGATCATCAGAGATCCGAGGGTTCAACTGGTCCGTATACTACAGAAATTGGCTATAGCTTTAACAGCTGGCGTTTGTTTCTTGGGCACGCCCCGACTAACACAAGCCGGGGTTCAAGACGTCCAAGGGGCTCTGTTCATCATCATAGCTGAGAACACGTTCAGCCCCATGTATTCAGTTCTTCACATGTTTCCTGAGGAGTTTCCGTTGTTCAACAGAGAACTTAAGGCTGGACTGTACTCCACGCCGGTCTATTATACTGCCAGAATGATCGCTTTGTTCCCAGGGCTGTTGATAGAGCCGGTGCTGTTCACTGGTGTGGTGTATTGGCTCGCCGGGCTACGGTACAGTGCCTACGCCATCGGATTGACCATATTCATCTCGATTCTGGTGCTCAACGTCGCCATAGCGTGCGGTTCGTTCTTCTCGTGCGCTTTTGGCTCGATGCCGTTGGCGATCGCCTATCTGGTGCCCTTTGACTATTCCCTAATGATGACATCCGGGATATTCATCAAATTAAGCTCTATTCCTCGCTACGTGGCGTGGATCCGCTACCTGTCCTGGCTGATGTACTCGAACGAAGCGATGTCCATAGTCCAGTGGGACGGCGTTGAGAACATCACGTGTACAAACTCGAATTCAACTGGCGTTCCTTGCGTGAGCACCGGCGACGAAGTTCTCATGCAGTACGATTTCACGAGCAGCAACCTCTGGCTGGATATATCGGCGTTGCTGCTGCTCTACATCACCTTCCATCTCCTCGCGCTGCTGGCCCTTAGATACAGAACGAGAAGAAAATGA

Protein

MGKKADTTKRSADNSPEKSESPQPLQSTSYELLPADLVYIDSGIKTSPVKYDSLYPEVEEVFGVPRSPRPCTLVWRDVTVHVKLKNGRLKRLVNNVSGIAKPGTLIALMGPSGAGKTTLMSALAHRSPFGTVIDGEIIMNGRPVCSYVDRESGYMHQDDIFAENLTVIEHLTVMARLRMDRRTSTVARKRRVNQLMRQLSLYESRFTRIGGLDGHKTLSGGERKRLAFATELLTDPGLLFCDEPTTGLDSSSALKLVSLLRASAAQGKTVICTIHQPSSELMAHFDKLVLLAEGRIAFAGNASAALGFFESLGYHCPLTYNPTDYFIKVLALTPGSEAASRHAIKSICDRFAVSDVAKELDMEIHLEYHLMDNEVEDSRRLRGDSFRPPHFYTKIMWLVYRYLLMIIRDPRVQLVRILQKLAIALTAGVCFLGTPRLTQAGVQDVQGALFIIIAENTFSPMYSVLHMFPEEFPLFNRELKAGLYSTPVYYTARMIALFPGLLIEPVLFTGVVYWLAGLRYSAYAIGLTIFISILVLNVAIACGSFFSCAFGSMPLAIAYLVPFDYSLMMTSGIFIKLSSIPRYVAWIRYLSWLMYSNEAMSIVQWDGVENITCTNSNSTGVPCVSTGDEVLMQYDFTSSNLWLDISALLLLYITFHLLALLALRYRTRRK

Description

Part of a membrane-spanning permease system necessary for the transport of pigment precursors into pigment cells responsible for eye color. Scarlet and white complex transports a metabolic intermediate (such as 3-hydroxy kynurenine) from the cytoplasm into the pigment granules.

Subunit

Heterodimer of scarlet with white.

Similarity

Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.

Keywords

ATP-binding   Complete proteome   Membrane   Nucleotide-binding   Pigment   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Protein scarlet

Uniprot

F1SZW3   M1G5M9   M1G4Y3   A0A2H1VY39   A0A194Q9K4   A0A212F0I6   + More
A0A1C8V5Z9   A0A194QQY5   A0A336MKY5   A0A336L180   A0A0K0LSP5   A0A067RB62   B0WJT2   A0A0C9Q8V2   J9HTX2   A0A2Z5ZBK5   A0A1S4G5D4   B4L9J1   B4MMH4   A0A182Y7S7   A0A182K3F5   A0A0A1WMB2   B4LI52   A0A182QPW2   A0A0M5J0V5   B3M4H8   B4J0W2   A0A182FMA6   A0A182LY19   A0A182R9H5   A0A0M4EJ42   A0A182PNR9   A0A182W4J2   A0A182MZI6   W5JKY4   A0A0K8WJK6   A0A034W8J1   B4PKE0   B4QMU2   A0A2H4TES7   A0A1W4WEG5   A0A1W4UTM6   S5M3P7   B3NHZ3   P45843   B4HJN9   A0A1A9W3A0   A0A3B0JYH6   Q29EH9   B4H215   A0A182XE05   A0A182HGL8   A0A182USM0   A0A1I8MRT6   W8B3S8   W8C232   A0A288W7L2   A0A1A9UIG1   Q867Z8   A0A1B0A6Z1   A0A1B0B6N3   A0A1A9YSS0   Q7QFI6   A0A084VJE8   A0A0L0C1S9   A0A182JB74   A0A1B0ESG4   A0A1W4WFG3   A0A0K8U6H0   A0A3B0K1A8   U4UAU9   A0A2Z5TXK4   A0A158NHH1   A0A182HAN7   A0A1B0FJY0   A0A2M4CP41   A0A1B6DWZ9   A0A1W4WFR4   A0A3Q0IQI1   A0A3R5YN91   A0A026WEA3   A0A2P2I4T6   A0A154P0I7   A0A1W4WFG8   A0A087ZW43   A0A0M9A894   E9G786   A0A3B0KMP7   A0A1W4W3X7   E0VCR4   A0A2Z6DUK0   A0A0P4XA18   A0A1B6CHQ0   A0A1B6GRU4   A0A164K8J4   A0A151XFE2   A0A1B0D1T3  

Pubmed

26354079    22118469    28053351    25555987    24845553    17510324    + More
17994087    25244985    25830018    20920257    23761445    25348373    17550304    22936249    29121518    8544833    10731132    12537572    2503416    11294610    15632085    25315136    24495485    12364791    24438588    26108605    23537049    21347285    26483478    24508170    21292972    20566863   

EMBL

AB588821    BAK08373.1    JQ687130    AFZ40747.1    JQ687131    AFZ40748.1    + More
ODYU01005100    SOQ45636.1    KQ459472    KPJ00091.1    AGBW02011105    OWR47211.1    KU754478    ANW09740.1    KQ461175    KPJ07918.1    UFQS01001252    UFQT01001252    SSX09936.1    SSX29659.1    UFQS01001616    UFQT01001616    SSX11618.1    SSX31185.1    KP120763    AJD07060.1    KK852575    KDR20988.1    DS231964    EDS29449.1    GBYB01010698    JAG80465.1    CH478356    EJY58108.1    LC368082    BBC77941.1    CH933816    EDW17366.1    CH963847    EDW73319.1    GBXI01014305    JAC99986.1    CH940647    EDW68596.1    AXCN02001274    CP012525    ALC43574.1    CH902618    EDV40472.1    CH916366    EDV95783.1    AXCM01002858    ALC43988.1    ADMH02001140    ETN63958.1    GDHF01000973    JAI51341.1    GAKP01008864    JAC50088.1    CM000159    EDW94838.1    CM000363    CM002912    EDX10734.1    KMZ00060.1    KY849652    ATY74530.1    BT150167    AGR42668.1    CH954178    EDV52079.1    U39739    AE014296    BT010208    BT011131    X76201    CH480815    EDW41766.1    OUUW01000012    SPP87104.1    CH379070    EAL30082.3    CH479203    EDW30367.1    APCN01005672    GAMC01010760    JAB95795.1    GAMC01010761    JAB95794.1    KX880378    ARS88259.1    AY172185    AY172186    AAO65145.1    JXJN01009178    AAAB01008846    EAA06599.4    ATLV01013553    KE524867    KFB38092.1    JRES01000997    KNC26260.1    AJWK01005203    GDHF01030082    GDHF01007181    JAI22232.1    JAI45133.1    SPP87103.1    KB632220    ERL90182.1    LC322271    BBB02494.1    ADTU01015823    ADTU01015824    JXUM01123025    KQ566670    KXJ69920.1    CCAG010018840    GGFL01002912    MBW67090.1    GEDC01007108    JAS30190.1    MH172522    QAA95929.1    KK107293    EZA53359.1    IACF01003431    LAB69047.1    KQ434792    KZC05435.1    KQ435713    KOX79247.1    GL732534    EFX84423.1    SPP87106.1    DS235063    EEB11170.1    LC380914    BBD76029.1    GDIP01246055    JAI77346.1    GEDC01024302    JAS12996.1    GECZ01004613    JAS65156.1    LRGB01003372    KZS03048.1    KQ982194    KYQ59055.1    AJVK01022322   

Proteomes

UP000053268    UP000007151    UP000053240    UP000027135    UP000002320    UP000008820    + More
UP000009192    UP000007798    UP000076408    UP000075881    UP000008792    UP000075886    UP000092553    UP000007801    UP000001070    UP000069272    UP000075883    UP000075900    UP000075885    UP000075920    UP000075884    UP000000673    UP000002282    UP000000304    UP000192223    UP000192221    UP000008711    UP000000803    UP000001292    UP000091820    UP000268350    UP000001819    UP000008744    UP000076407    UP000075840    UP000075903    UP000095301    UP000078200    UP000092445    UP000092460    UP000092443    UP000007062    UP000030765    UP000037069    UP000075880    UP000092461    UP000030742    UP000005205    UP000069940    UP000249989    UP000092444    UP000079169    UP000053097    UP000076502    UP000005203    UP000053105    UP000000305    UP000009046    UP000076858    UP000075809    UP000092462   

PRIDE

F1SZW3    M1G5M9    M1G4Y3    S5M3P7    P45843   

Pfam

PF01061   ABC2_membrane        + More
PF00005   ABC_tran

Interpro

IPR003593   AAA+_ATPase        + More
IPR013525   ABC_2_trans       
IPR027417   P-loop_NTPase       
IPR003439   ABC_transporter-like       
IPR017871   ABC_transporter_CS       
IPR005284   Pigment_permease/Abcg       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

F1SZW3   M1G5M9   M1G4Y3   A0A2H1VY39   A0A194Q9K4   A0A212F0I6   + More
A0A1C8V5Z9   A0A194QQY5   A0A336MKY5   A0A336L180   A0A0K0LSP5   A0A067RB62   B0WJT2   A0A0C9Q8V2   J9HTX2   A0A2Z5ZBK5   A0A1S4G5D4   B4L9J1   B4MMH4   A0A182Y7S7   A0A182K3F5   A0A0A1WMB2   B4LI52   A0A182QPW2   A0A0M5J0V5   B3M4H8   B4J0W2   A0A182FMA6   A0A182LY19   A0A182R9H5   A0A0M4EJ42   A0A182PNR9   A0A182W4J2   A0A182MZI6   W5JKY4   A0A0K8WJK6   A0A034W8J1   B4PKE0   B4QMU2   A0A2H4TES7   A0A1W4WEG5   A0A1W4UTM6   S5M3P7   B3NHZ3   P45843   B4HJN9   A0A1A9W3A0   A0A3B0JYH6   Q29EH9   B4H215   A0A182XE05   A0A182HGL8   A0A182USM0   A0A1I8MRT6   W8B3S8   W8C232   A0A288W7L2   A0A1A9UIG1   Q867Z8   A0A1B0A6Z1   A0A1B0B6N3   A0A1A9YSS0   Q7QFI6   A0A084VJE8   A0A0L0C1S9   A0A182JB74   A0A1B0ESG4   A0A1W4WFG3   A0A0K8U6H0   A0A3B0K1A8   U4UAU9   A0A2Z5TXK4   A0A158NHH1   A0A182HAN7   A0A1B0FJY0   A0A2M4CP41   A0A1B6DWZ9   A0A1W4WFR4   A0A3Q0IQI1   A0A3R5YN91   A0A026WEA3   A0A2P2I4T6   A0A154P0I7   A0A1W4WFG8   A0A087ZW43   A0A0M9A894   E9G786   A0A3B0KMP7   A0A1W4W3X7   E0VCR4   A0A2Z6DUK0   A0A0P4XA18   A0A1B6CHQ0   A0A1B6GRU4   A0A164K8J4   A0A151XFE2   A0A1B0D1T3  

PDB

6FFC     E-value=5.22793e-73,     Score=700

KEGG

100862765    K21396 ATP-binding cassette, subfamily G (WHITE), eye pigment precursor transporter | (RefSeq) -w-2,

GO

GO:0005524   GO:0016021   GO:0016887   GO:0015842   GO:0005275   GO:0098793   GO:0006727   GO:0006856   GO:0090740   GO:0055085   GO:0031409   GO:0042626   GO:0005886   GO:0015416   GO:0016020   GO:0016765   GO:0005634   GO:0006355   GO:0016818   GO:0003676   GO:0008026   GO:0016597  

Subcellular location

Membrane  
Cytoplasmic granule membrane  

Length:

670

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

125.68993

Exp number, first 60 AAs:

0

Total prob of N-in:

0.48559

outside

1  -  411

TMhelix

412  -  434

inside

435  -  446

TMhelix

447  -  469

outside

470  -  493

TMhelix

494  -  516

inside

517  -  522

TMhelix

523  -  545

outside

546  -  554

TMhelix

555  -  577

inside

578  -  583

TMhelix

584  -  603

outside

604  -  640

TMhelix

641  -  663

inside

664  -  670

 

 

Pi

182.208982

Theta

162.571229

Tajima's D

0.430754

CLR

0.442491

CSRT

0.500074996250187

Interpretation

Uncertain