Gene

KWMTBOMO05893

Pre Gene Modal

BGIBMGA002778

Annotation

PREDICTED:_DNA_repair_protein_RAD51_homolog_4_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr10(+):13567986-13571015      View in EpiBrowser

Full name

tRNA-splicing ligase RtcB homolog      

Location in the cell

PlasmaMembrane   Reliability : 1.217

CDS

ATGCTCAATAGAGGAATCCCAGCTAAGACGATTACAGAATTATGTGGAATAGCAGGCTCAGGTAAAACACAGTTAGCCCTACAAATAGCTATTAATTGTGCAAAAGAGACTCACAAAACAGTGTTGTATATTGACACCAAAGGGGATTTCTCAGCTCTTAGAATTCAAAAGATATTAGAAAAATGTCAATACTCTTTTAAGGAAGTTGCAGCCATAATGAGTAGAATTCACATAAGCTATATTTGGACAATGGAAGAACTGGTGAACTTGTTTAAAAACCTGAAGAATGGAGAATTAGTAATAGATAATTTGGTGTTGCTGGTCATAGACTCTTTACCTTCCCTGATGTTTCAATATCTTGGTGAAGATAATAAACTAGGTTTATCATTATTAAATTCGTTTGTGAATTATAGTCGGTTTATCTGCAAACAGCTGAATATAGGAATAATCTGTATAAACATGCAAACAAGATGGGTGGACCAGGATTTAACAGATGTGGAAGATGAAGAAAATTCCACTGCGTACAAGGACTCTTTTACAGAAAAACGGTACCGTTGCTTAGGAAGGTACTGGCAACACATACCTACATTAGTGCTTGAACTGGAAAAAATAAAAGAAAATGATAATGAAAACAACTCGGGTATAAAAATAACAGTATTACACTCTATCGATAGTGACTATGAAAACCGTCATTGTATTTTATGTGTAGGCGAGTCTGGAGTCACGTAA

Protein

MLNRGIPAKTITELCGIAGSGKTQLALQIAINCAKETHKTVLYIDTKGDFSALRIQKILEKCQYSFKEVAAIMSRIHISYIWTMEELVNLFKNLKNGELVIDNLVLLVIDSLPSLMFQYLGEDNKLGLSLLNSFVNYSRFICKQLNIGIICINMQTRWVDQDLTDVEDEENSTAYKDSFTEKRYRCLGRYWQHIPTLVLELEKIKENDNENNSGIKITVLHSIDSDYENRHCILCVGESGVT

Description

Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs.

Catalytic Activity

ATP + (ribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(ribonucleotide)(m) = (ribonucleotide)(n+m) + AMP + diphosphate.

Subunit

Catalytic component of the tRNA-splicing ligase complex.

Similarity

Belongs to the RtcB family.

Uniprot

A0A2W1BPY1   A0A2A4J5G7   A0A194QRE2   A0A2H1WZ79   S4PF69   A0A212EKR9   + More
A0A1B6HIB9   A0A088AVM4   A0A1B6FUM4   A0A2J7R7S3   A0A2A3ELZ5   A0A2Z5TRF0   A0A224XHJ1   A0A0A9Z1L7   A0A084WEP2   A0A0P4VSX3   R4FLU7   A0A1I8MAC4   A0A1I8MAB5   A0A067RCD4   A0A291S6X0   A0A0N0BHU5   A0A182YKU3   A0A1Y1LXQ1   A0A182WLL7   A0A182LXU6   A0A1B6DPW6   J9KMC4   A0A182TZ19   A0A1A9WJY9   A0A154PD57   Q16EQ5   A0A182RDL1   A0A1S4G396   A0A182JSH2   A0A026WS72   A0A182Q5R1   A0A182I1B5   A0A2P8XH69   A0A182XPB3   A0A034WK96   D6X266   A0A182V087   W5M1W8   A0A2D0QDU3   A0A1A9V205   A0A1I8Q630   A0A1S3EW35   A0A182GWR7   E2AE37   A0A182T893   A0A023EMI4   A0A2S2PX68   A0A3B1KA83   L5JSR2   A0A182PG62   A0A3Q3WV54   A0A0E9X714   A0A182NK24   A0A3Q3GUF3   U4URR5   N6TVI2   E9IWH5   G3GTU6   I3LTG9   A0A3Q1BYX0   S7MHT8   F1R474   H0X1G7   A0A1B0B5W2   A0A1A9XIR1   D6R734   G1PKN6   A0A182FH52   B5DFH5   A0A091PNZ9   A0A3Q1GRX9   A0A286Y1V6   A0A287D3P6   A0A1U7V456   A0A1U7UUP7   A0A341AD13   A0A3Q1KE85   A0A2U3V262   B0XK02   Q6NYZ3   A0A2K6USG1   A0A2Y9K7X7   A0A182KNX5   A7UU35   A0A2K5PZE1   A0A2K5D7N8   A0A1W4Z0V0   A0A0P7U808  

EC Number

6.5.1.3

Pubmed

28756777    26354079    23622113    22118469    26760975    25401762    + More
26823975    24438588    27129103    25315136    24845553    28992199    25244985    28004739    17510324    24508170    29403074    25348373    18362917    19820115    26483478    20798317    24945155    25329095    23258410    25613341    23537049    21282665    21804562    30723633    23594743    21993624    15489334    15057822    15632090    20966253    12364791   

EMBL

KZ149998    PZC75377.1    NWSH01003113    PCG66918.1    KQ461175    KPJ07909.1    + More
ODYU01012212    SOQ58400.1    GAIX01006735    JAA85825.1    AGBW02014216    OWR42081.1    GECU01033317    JAS74389.1    GECZ01015881    JAS53888.1    NEVH01006727    PNF36887.1    KZ288220    PBC32189.1    FX985803    BBA93690.1    GFTR01004471    JAW11955.1    GBHO01004477    GDHC01017963    JAG39127.1    JAQ00666.1    ATLV01023241    KE525341    KFB48686.1    GDKW01000320    JAI56275.1    GAHY01001984    JAA75526.1    KK852556    KDR21422.1    MF433008    ATL75359.1    KQ435745    KOX76598.1    GEZM01047394    JAV76855.1    AXCM01000789    GEDC01009576    JAS27722.1    ABLF02034685    KQ434874    KZC09727.1    CH478615    EAT32714.1    KK107119    EZA58516.1    AXCN02000497    APCN01000049    PYGN01002141    PSN31350.1    GAKP01003858    JAC55094.1    KQ971371    EFA10219.1    AHAT01005635    JXUM01019817    KQ560556    KXJ81902.1    GL438827    EFN68270.1    GAPW01003061    JAC10537.1    GGMS01000780    MBY69983.1    KB031150    ELK01786.1    GBXM01010045    JAH98532.1    KB632334    ERL92770.1    APGK01058789    KB741292    ENN70302.1    GL766526    EFZ15082.1    JH000022    EGV94391.1    AEMK02000080    DQIR01126082    DQIR01183451    HDA81558.1    KE161458    EPQ03939.1    CU929413    AAQR03133417    AAQR03133418    AAQR03133419    AAQR03133420    JXJN01008888    HM124772    ADF97633.1    AAPE02043925    AC095947    BC169062    CH473948    AAI69062.1    EDM05454.1    KK662987    KFQ09385.1    AAKN02033115    AGTP01050539    DS233663    EDS31033.1    BC066407    AAH66407.1    AAAB01008960    EDO63813.1    JARO02007639    KPP63726.1   

Proteomes

UP000218220    UP000053240    UP000007151    UP000005203    UP000235965    UP000242457    + More
UP000030765    UP000095301    UP000027135    UP000053105    UP000076408    UP000075920    UP000075883    UP000007819    UP000075902    UP000091820    UP000076502    UP000008820    UP000075900    UP000075881    UP000053097    UP000075886    UP000075840    UP000245037    UP000076407    UP000007266    UP000075903    UP000018468    UP000221080    UP000078200    UP000095300    UP000081671    UP000069940    UP000249989    UP000000311    UP000075901    UP000018467    UP000010552    UP000075885    UP000261620    UP000075884    UP000261660    UP000030742    UP000019118    UP000001075    UP000008227    UP000257160    UP000000437    UP000005225    UP000092460    UP000092443    UP000001074    UP000069272    UP000002494    UP000257200    UP000005447    UP000005215    UP000189704    UP000252040    UP000265040    UP000245320    UP000002320    UP000233220    UP000248482    UP000075882    UP000007062    UP000233040    UP000233020    UP000192224    UP000034805   

PRIDE

G3GTU6    I3LTG9   

Pfam

PF08423   Rad51        + More
PF05971   Methyltransf_10
PF01139   RtcB

Interpro

IPR027417   P-loop_NTPase        + More
IPR020588   RecA_ATP-bd       
IPR013632   DNA_recomb/repair_Rad51_C       
IPR016467   DNA_recomb/repair_RecA-like       
IPR003593   AAA+_ATPase       
IPR018247   EF_Hand_1_Ca_BS       
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR017182   METTL16/PsiM       
IPR010286   METTL16/RlmF       
IPR029063   SAM-dependent_MTases       
IPR027513   RtcB_euk       
IPR036025   RtcB-like_sf       
IPR001233   RtcB       
IPR033925   Rad51_DMC1_RadA       
IPR010995   DNA_repair_Rad51/TF_NusA_a-hlx       

SUPFAM

SSF52540   SSF52540        + More
SSF47473   SSF47473       
SSF53335   SSF53335       
SSF103365   SSF103365       
SSF47794   SSF47794       

Gene 3D

3.90.1860.10    

CDD

cd01123  Rad51_DMC1_radA

ProteinModelPortal

A0A2W1BPY1   A0A2A4J5G7   A0A194QRE2   A0A2H1WZ79   S4PF69   A0A212EKR9   + More
A0A1B6HIB9   A0A088AVM4   A0A1B6FUM4   A0A2J7R7S3   A0A2A3ELZ5   A0A2Z5TRF0   A0A224XHJ1   A0A0A9Z1L7   A0A084WEP2   A0A0P4VSX3   R4FLU7   A0A1I8MAC4   A0A1I8MAB5   A0A067RCD4   A0A291S6X0   A0A0N0BHU5   A0A182YKU3   A0A1Y1LXQ1   A0A182WLL7   A0A182LXU6   A0A1B6DPW6   J9KMC4   A0A182TZ19   A0A1A9WJY9   A0A154PD57   Q16EQ5   A0A182RDL1   A0A1S4G396   A0A182JSH2   A0A026WS72   A0A182Q5R1   A0A182I1B5   A0A2P8XH69   A0A182XPB3   A0A034WK96   D6X266   A0A182V087   W5M1W8   A0A2D0QDU3   A0A1A9V205   A0A1I8Q630   A0A1S3EW35   A0A182GWR7   E2AE37   A0A182T893   A0A023EMI4   A0A2S2PX68   A0A3B1KA83   L5JSR2   A0A182PG62   A0A3Q3WV54   A0A0E9X714   A0A182NK24   A0A3Q3GUF3   U4URR5   N6TVI2   E9IWH5   G3GTU6   I3LTG9   A0A3Q1BYX0   S7MHT8   F1R474   H0X1G7   A0A1B0B5W2   A0A1A9XIR1   D6R734   G1PKN6   A0A182FH52   B5DFH5   A0A091PNZ9   A0A3Q1GRX9   A0A286Y1V6   A0A287D3P6   A0A1U7V456   A0A1U7UUP7   A0A341AD13   A0A3Q1KE85   A0A2U3V262   B0XK02   Q6NYZ3   A0A2K6USG1   A0A2Y9K7X7   A0A182KNX5   A7UU35   A0A2K5PZE1   A0A2K5D7N8   A0A1W4Z0V0   A0A0P7U808  

PDB

2ZUD     E-value=0.000223622,     Score=103

KEGG

101744594    K10871 RAD51-like protein 3 | (RefSeq) DNA repair protein RAD51 homolog 4

PATHWAY

03440    Homologous recombination - Bombyx mori (domestic silkworm)

GO

GO:0008094   GO:0003677   GO:0006281   GO:0005524   GO:0003697   GO:0000784   GO:0005657   GO:0000723   GO:0000724   GO:0033063   GO:0005509   GO:0005813   GO:0000400   GO:0042148   GO:0043015   GO:0036297   GO:0051726   GO:0008168   GO:0072669   GO:0006388   GO:0046872   GO:0003972   GO:0005634   GO:0006355   GO:0016818   GO:0003676   GO:0008026   GO:0016597  

PANTHER

PTHR13393   PTHR11118  

Length:

242

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.41155

Exp number, first 60 AAs:

0.0039

Total prob of N-in:

0.07958

outside

1  -  242

 

 

Pi

51.029053

Theta

69.389926

Tajima's D

0.20767

CLR

11.47021

CSRT

0.424428778561072

Interpretation

Uncertain