SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05890  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA002931
Annotation
putative_Chromodomain_helicase-DNA-binding_protein_Mi-2-like_protein_[Danaus_plexippus]
Full name
Chromodomain-helicase-DNA-binding protein Mi-2 homolog      
Alternative Name
ATP-dependent helicase Mi-2
Location in the cell
Nuclear   Reliability : 4.229
 

Sequence

CDS
ATGGCATCAGATGAGGAAGTGGACGGCTCTTTTGCAGGTGATGAGGAAGTAGAGGAAGGTGAGGGTCAAAATGACAATTCCGGAGATAGTGACGAGGCTCCACCAAAGGAAGATGAAGATTATTCCCCTGAAGATGGTAGAAAAAAGAAAAAGGGAAAGAAAAGGAAAGCCAGAGGAGAAGAAAAAAAGGGAAGAAAGAAAAAGAAGAAGCGAAAGAATGAAAGTGAAGATGATGATGATTTTGGCCTCGAGATGGAAGCAGAAGGTGACAGTGATTATGCACTGAGCGCTGTCTCTTCAAGCAAGAAATCCCGTAAAGGTCGAAGTAGCAAACACAACACACCATCCACAACTACAGCATCAGACTCTGGCTCTGGTATGCCAACAGTCGAGGAGGTGTGCTCCTCGTTCGGCCTTACCGATGTTGACATACAATATGCGGATGCGGACTACGAAAACTTGACTACATACAAACTGTTTCAACAACATGTTCGTCCAATGCTCGTTAAAGAGAATCCAAAGGTGCCAGTATCAAAGTTAATGATGCTAGTAGCTGCAAAATGGCGGATGTTCTGTGAAACGAATCCACACTTAAGCACTAGTGTACCACAAAGTATGGGCTCTGAAGAGAATACAAATACTTCTGCTACTTCTGACTATGTCTCTAAGAGACCCGGACGCACACCCAAAGAAGCAAAGACTGATGAGACAATAGAGGAGCCCGAAGAAGAAGAGGAGGAAGAAGCAAGTGACGAAGGCGCTACTGTGCCGCGGAAACGTGGACGCAAGCCCAAGAATGCGACCGGCGCCGTCACGCCACGAGGCAAGCCCGGCAGGAAGCCTAAAGTACCTACACTGAAGATCAAGTTCAGCAAGAGAAAACGAACCAGCAGCGAGGAGGAACAAGAAGGCAGCGCTGTAAATTCAGATTCAGACGCCGAGTTCGAGCAGATGTTAGCTGAAGCCGAGGAAACAAAGCCTCCTGTTGCAGCTGCAGCTGACGAAGCCGCGCCACCTAAAGAAGAAGATCCTACAGCGGCGCTACCTAAAAAGAAGGCAAAGACAAAGATCGGAAACAAATCTAAAAAGAAAAGGAAGTTGAAGACGACCAGCAAGTTTCCTGATGGTGCTGAGGGAGAGCACGAACATCAGGACTATTGTGAGGTGTGTCAGCAAGGCGGCGAGATAATTCTGTGTGACACATGTCCACGGGCCTACCACCTCGTGTGCCTCGACCCCGAGCTCGAGGAGACGCCGGAGGGCCGCTGGTCGTGTCCGCACTGCGAGGCCGAGCCCGCACCCGACAATGACGACGACGATGAACATCAGGAGTTTTGCAGAATTTGTAAGGACGGCGGCGAGTTGTTATGCTGCGATTCTTGTCCTTCAGCGTATCATCGGTTCTGCTTGAATCCGCCGCTTGAAGAAATTCCCGATGGCGAGTGGAAATGTCCCAGATGCAGTTGTCCACCATTGGATGGAAAAGTGGCCAAAATTTTAACTTGGCGTTGGAAGGAACAGTCAAGCAAGTCCAAGGCTCCGCGTTCAAGAGAATTTTTTGTGAAGTGGCATGAACGATCTTATTGGCACTGCAGCTGGATATCTGAACTACAGCTCGACGTGTTCCATCCACTAATGTATCGTTACTACATGCGTAAGTCGGATCCCGAAGAACCGCCTAAACTTGAAGAGCCCCTCGATGAACGAGATAGTAGGTACAAACGACTCAAAGATAAACAACAGGATACGGAATCTAACAACGAAAAATTACTCGAAGAGAAGTATTATAGATATGGCGTCAAACCTGAGTGGCTTGTAGTACACCGTGTGATCAACCATCGCACTTCAAGAGACGGCACTACATACTTTTTAGTCAAATGGAGAGATCTCTCATACGATCAGGCCACGTGGGAATCTGAGCATGAAGACATTGCCGGACTCAAGCAAGCCATGGACTATTATCAAGACATGCGAGCGTTCATAACGTCAGAGGGTAAGACTAAAGGCTTCAAAGGTAAGAAACCAGGTCGCAAAAGTAAGAACAAAGACCTCACGGACGAAGACGACAGCAGCGCCGGCCTACAAATGCGCCCCAAGAAATACAATCCGCCGCCTGATCGTCCTACCAGTAATCTCAATAAGAAATACGAAGACCAACCACAGTTTGTGTACGAAACCGGCATGCAGCTGCATCCTTACCAGCTAGAGGGTCTCAACTGGCTTCGGTATTCCTGGGGACAAGGCATCGACACCATACTGGCTGACGAGATGGGTCTCGGTAAAACCATCCAAACCGTTACATTCCTATACTCTCTATTCAAGGAAGGCCATTCTAAAGGACCTTTCTTGGTGTCCGTGCCGCTATCCACAATCATTAATTGGGAGAGGGAATTCGAGCTATGGGCACCGGACTTGTACTGTATAACATATGTAGGTGACAAAGATTCGAGGGCTGTGATCCGAGAGAATGAACTAACATTTGATGACGGTGCTAACAGAGGTGGCAGACCTTCTAAAATCAAGTCGCAAGTGAAATTTAATGTTTTACTCACTTCCTATGAATTGATCTCAATTGACTCTACGTGCTTAGGATCTATAGATTGGGCAGTTCTCGTTGTAGACGAAGCCCACAGACTGAAGAGTAATCAGTCGAAATTTTTCAGGCTTTTGGCCGGTTATCACATCAATTATAAATTGCTTCTTACGGGTACACCACTACAGAATAACTTGGAAGAGTTGTTCCATCTTCTCAATTTCTTAAATAAAGACAAGTTCAATGATCTCGCAGCATTCCAGAATGAGTTCGCTGACGTTTCGAAAGAAGAACAGGTGAAGAGGCTCCACGAAATGCTAGGGCCTCACATGTTGCGACGTTTGAAAGCTGACGTACTGAAAAACATGCCTACTAAGTCAGAGTTCATTGTCCGTGTAGAATTATCGCCCATGCAAAAGAAATATTATAAATACATTCTAACTAGGAATTATGAAGCTTTGAACCCCAAGAGTGGAGGTCAAACTGTTTCACTACTTAACGTCATGATGGACCTGAAGAAATGTTGTAATCATCCTTATCTATTCCCAGTCGCAGCGGAGGAAGCTCCGTTAGGTCCGCACGGAAATTATGACACGCAAGCTTTGATCAAAGCTTCTGGAAAACTCGTGCTCCTATCTAAAATGTTGAAACAATTGAAAGAGCAGGGTCATAGGGTACTGATTTTCTCACAGATGACGAAAATGTTGGATATACTTGAAGACTTCTTGGAGGGTGAGGGATACAAGTATGAAAGAATTGACGGTGGTATCACGGGAACGATCCGTCAAGAAGCCATAGATAGGTTTAATGCCCCGGGAGCCCAACAGTTTGTGTTCCTCTTGTCGACAAGAGCGGGAGGTCTGGGCATCAATTTGGCGACCGCCGACACTGTTATCATTTATGATTCCGATTGGAATCCTCACAATGACATTCAAGCTTTCTCTCGAGCGCATCGTATTGGCCAAGCCAACAAAGTTATGATTTATCGTTTTGTAACACGTAACAGCGTCGAAGAAAGAGTCACCCAAGTCGCTAAACGAAAAATGATGTTAACGCATTTGGTGGTGCGACCGGGCATGGGCGGAAAGGGAGCTAACTTCACTAAGCAAGAGTTGGATGATATTCTTCGATTCGGTACTGAAGAGCTGTTCAAAGAAGAGGAAGGCAAAGAGGAGGCTATTCATTATGACGATAGAGCTGTGGGTGAATTACTCGATCGGTCTAAGGAAGGAATAGAACAGAAAGAATCTTGGGCTAATGAATATCTTAGCTCTTTCAAAGTTGCTAGTTATTCCACTAAGGAAGGCGATGGTGAAGAGGAAGTCGATACAGAAATTATAAAACAGGAAGCAGAGAATACTGATCCTGCGTACTGGATCAAACTTCTCAGGCATCACTACGAACAACATCAAGAAGATCAAGCGCGGACGCTTGGGAAAGGCAAACGTGTACGTAAACAAGTTAACTACAACGATGGAAGTGTTGCGCAGACAGAAAACAGAGAGGATTCTACTTGGCAAGAGAATGGCTCGGACTATAATTCCGATTTCTCTCAAGGTAGCGAGGATGACAAAGAAGACGACGATTTTGATGAAAAGAATGATAATGGAGATCTGCTCAGTCGCCGGAGTAAGCGTCGCCTCGAAAAGCGAGAGGAACGCGACCGACCGCTGCCTCCATTACTGGCCAGAGTCGGCGGCAACATGGAAGTTCTCGGCTTCAACGCCAGGCAGAGGAAGTCATTCCTCAATGCTATCATGCGGTACGGGATGCCACCGCAGGACGCTTTCAACTCGCAGTGGTTAGTGAGAGATCTGCGCGGGAAGTCTGAGCGCAACTTCAAGGCCTACGTGTCGTTGTTCATGCGCCATCTCTGCGAACCGGGCGCCGACAACGCGGAAACATTCGCGGACGGCGTTCCGAGGGAAGGATTATCCCGTCAGCACGTTTTGACACGAATCGGGGTAATGAGTTTGATCAGGAAAAAGGTTCAGGAATTCGAACACATCAACGGGTACTACAGCATGCCGGAACTGGTGAGAAAACCAGTTGAGCCGGTGAAAGTGTCTGGGGCGAGTGAGAGTGCCGCCCCCAGTCCCGCGCCCTCCACCGCCACACCCATCACCTCCGCAGCACCCTCGCCCGCACCCACCTTGCTGCCTCACGGACAGGCAGCCACGCCCGCCACGCCCTCTGGCTCTGACAAGGACGATAAAGAGGAAACTAAAGATGACAAATTGGAAGTTAAAGATAAACTCAAAGCAGAACCGATGGATACGGCCGATGTCAAGGAGGATAGTGCGGAAGAAAAAGAATCACAAAAAGAAGACGAGAAAGAGGCCGAAAGACGTATGTCCGTTGACGAGGAACCTCCAAAAGATGAAGATAAAACTGATGAAAAGAAAGAAGGCAAAGAGTCACCTAAAGTTAAAGACGAATTGAAGGAAGAGACCGACAAGAAAGAGGATGTAAGAAGTGAAAAGGCGGCATCTGACGTCTCTGAGAAACCAAAAGAGGAGAAGAAGGAGGACGACGACGATGACGTTGTTCTGGTTAAAGAAGAGGAAGATCTCAAAGTAGAACGTCGCAAGTTCATGTTCAATATCGCCGACGGAGGCTTTACCGAACTCCATACTCTGTGGTTGAATGAAGAGCGAGCCGCCGCGCCCGGCAGGGAATACGAAATCTGGCACCGAAGACACGACTACTGGCTGCTGGCCGGAATCGTCACGCACGGATACGGTCGCTGGCAGGACATACAGAACGACCTGCGATTCGCGATCATTAACGAGCCATTCAAGATGGACGTCGGCAAAGGAAACTTCCTCGAGATTAAGAATAAGTTTTTGGCTCGGCGTTTTAAGCTTTTAGAACAAGCGTTAGTGATCGAGGAGCAGCTCCGTAGAGCGGCATACTTGAACCTCACACAAGATCCGAACCATCCCGCAATGTCCTTGAACGCGCGGTTCGCTGAAGTCGAGTGTCTTGCTGAGTCCCACCAGCATCTCAGCAAGGAGTCCCTCGCTGGGAACAAACCAGCCAACGCGGTGTTGCACAAGGTGCTGAACCAGCTGGAAGAGCTGCTGTCGGACATGAAGTCGGACGTGTCGCGGCTGCCGGCCACGCTGGCGCGCATCCCGCCCGTCGCGCAGCGCCTGCAGATGTCGGAGCGGTCCATCCTGTCGCGCCTCGCAGCCACCGCAGGCAACCCCGTGCCCGCTGCCCAAATGCCGCAGTTCCCGACCGGCTTCCAGCCCGGCGGCACGCTCCCCGGGTTCGCGGCGTCGGCCGCGACGGCGGCTAATTTCTCCAACTTCCGACCGCAGTACTCCGTGCCCGGACAGCCTACATCATCCTCTAACTCGAATAAATCATAA
Protein
MASDEEVDGSFAGDEEVEEGEGQNDNSGDSDEAPPKEDEDYSPEDGRKKKKGKKRKARGEEKKGRKKKKKRKNESEDDDDFGLEMEAEGDSDYALSAVSSSKKSRKGRSSKHNTPSTTTASDSGSGMPTVEEVCSSFGLTDVDIQYADADYENLTTYKLFQQHVRPMLVKENPKVPVSKLMMLVAAKWRMFCETNPHLSTSVPQSMGSEENTNTSATSDYVSKRPGRTPKEAKTDETIEEPEEEEEEEASDEGATVPRKRGRKPKNATGAVTPRGKPGRKPKVPTLKIKFSKRKRTSSEEEQEGSAVNSDSDAEFEQMLAEAEETKPPVAAAADEAAPPKEEDPTAALPKKKAKTKIGNKSKKKRKLKTTSKFPDGAEGEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEETPEGRWSCPHCEAEPAPDNDDDDEHQEFCRICKDGGELLCCDSCPSAYHRFCLNPPLEEIPDGEWKCPRCSCPPLDGKVAKILTWRWKEQSSKSKAPRSREFFVKWHERSYWHCSWISELQLDVFHPLMYRYYMRKSDPEEPPKLEEPLDERDSRYKRLKDKQQDTESNNEKLLEEKYYRYGVKPEWLVVHRVINHRTSRDGTTYFLVKWRDLSYDQATWESEHEDIAGLKQAMDYYQDMRAFITSEGKTKGFKGKKPGRKSKNKDLTDEDDSSAGLQMRPKKYNPPPDRPTSNLNKKYEDQPQFVYETGMQLHPYQLEGLNWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLFKEGHSKGPFLVSVPLSTIINWEREFELWAPDLYCITYVGDKDSRAVIRENELTFDDGANRGGRPSKIKSQVKFNVLLTSYELISIDSTCLGSIDWAVLVVDEAHRLKSNQSKFFRLLAGYHINYKLLLTGTPLQNNLEELFHLLNFLNKDKFNDLAAFQNEFADVSKEEQVKRLHEMLGPHMLRRLKADVLKNMPTKSEFIVRVELSPMQKKYYKYILTRNYEALNPKSGGQTVSLLNVMMDLKKCCNHPYLFPVAAEEAPLGPHGNYDTQALIKASGKLVLLSKMLKQLKEQGHRVLIFSQMTKMLDILEDFLEGEGYKYERIDGGITGTIRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFGTEELFKEEEGKEEAIHYDDRAVGELLDRSKEGIEQKESWANEYLSSFKVASYSTKEGDGEEEVDTEIIKQEAENTDPAYWIKLLRHHYEQHQEDQARTLGKGKRVRKQVNYNDGSVAQTENREDSTWQENGSDYNSDFSQGSEDDKEDDDFDEKNDNGDLLSRRSKRRLEKREERDRPLPPLLARVGGNMEVLGFNARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEPGADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHINGYYSMPELVRKPVEPVKVSGASESAAPSPAPSTATPITSAAPSPAPTLLPHGQAATPATPSGSDKDDKEETKDDKLEVKDKLKAEPMDTADVKEDSAEEKESQKEDEKEAERRMSVDEEPPKDEDKTDEKKEGKESPKVKDELKEETDKKEDVRSEKAASDVSEKPKEEKKEDDDDDVVLVKEEEDLKVERRKFMFNIADGGFTELHTLWLNEERAAAPGREYEIWHRRHDYWLLAGIVTHGYGRWQDIQNDLRFAIINEPFKMDVGKGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNLTQDPNHPAMSLNARFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKSDVSRLPATLARIPPVAQRLQMSERSILSRLAATAGNPVPAAQMPQFPTGFQPGGTLPGFAASAATAANFSNFRPQYSVPGQPTSSSNSNKS

Summary

Description
Vital role in development. Protein binds to a portion of Hunchback (HB) protein that is critical for repression of bithorax complex (BXC) genes. May also function in polycomb group (PcG) repression of Hox genes.
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Similarity
Belongs to the SNF2/RAD54 helicase family.
Keywords
ATP-binding   Complete proteome   DNA-binding   Helicase   Hydrolase   Metal-binding   Nucleotide-binding   Nucleus   Phosphoprotein   Reference proteome   Repeat   Repressor   Transcription   Transcription regulation   Zinc   Zinc-finger  
Feature
chain  Chromodomain-helicase-DNA-binding protein Mi-2 homolog
EC Number
3.6.4.12
EMBL
BABH01019165    RSAL01000003    RVE54788.1    KZ149998    PZC75373.1    ODYU01012212    + More
SOQ58397.1    AGBW02014216    OWR42084.1    KQ459302    KPJ01702.1    KQ461175    KPJ07906.1    JTDY01001200    KOB74563.1    JR037514    AEY57807.1    JR037513    AEY57806.1    GFDF01008377    JAV05707.1    ADTU01022755    ADTU01022756    KZ288266    PBC30200.1    KQ976745    KYM75478.1    KQ982014    KYN30630.1    KK107021    EZA62353.1    KQ980487    KYN15917.1    KQ971371    KYB25528.1    EFA09958.2    AJVK01022228    AJVK01022229    GL438838    EFN68184.1    DS235872    EEB19526.1    KQ435718    KOX78964.1    KQ982409    KYQ56728.1    QOIP01000011    RLU16965.1    FX985691    BBA84429.1    AAZX01007436    GEZM01063288    JAV69134.1    GL451091    EFN80104.1    NNAY01002375    OXU21421.1    GBXI01011944    JAD02348.1    GANO01000498    JAB59373.1    KT369802    AML25531.1    KQ978456    KYM93900.1    DS231882    EDS42896.1    GFDL01014997    JAV20048.1    CP012525    ALC44637.1    GFDL01014960    JAV20085.1    CH902618    EDV41087.2    GEDC01009872    JAS27426.1    CH940647    EDW70829.2    GBHO01023193    GBRD01001266    JAG20411.1    JAG64555.1    CH954178    EDV52426.2    CM000159    EDW95263.1    KRK02335.1    GEDC01008033    JAS29265.1    GBRD01001268    JAG64553.1    GEDC01012984    JAS24314.1    CH916366    EDV97502.1    GBHO01023191    GBRD01001269    JAG20413.1    JAG64552.1    CM002912    KMZ00632.1    CH379069    EDY73831.2    KRT08345.1    GBRD01001270    GDHC01006982    JAG64551.1    JAQ11647.1    GDHC01018196    JAQ00433.1    AE014296    AGB94771.1    ACZ94747.1    AAX52739.1    AF119716    AY113368    OUUW01000002    SPP77262.1    CVRI01000048    CRK98590.1    ABLF02034500   
Pfam
PF08073   CHDNT        + More
PF00176   SNF2_N
PF06465   DUF1087
PF08074   CHDCT2
PF00385   Chromo
PF00628   PHD
PF06461   DUF1086
PF00271   Helicase_C
PF17976   zf-RING_12
PF17978   zf-RING_14
PF00240   ubiquitin
Interpro
IPR038718   SNF2-like_sf        + More
IPR027417   P-loop_NTPase       
IPR000330   SNF2_N       
IPR019787   Znf_PHD-finger       
IPR001650   Helicase_C       
IPR000953   Chromo/chromo_shadow_dom       
IPR012958   CHD_N       
IPR014001   Helicase_ATP-bd       
IPR002464   DNA/RNA_helicase_DEAH_CS       
IPR012957   CHD_C2       
IPR023780   Chromo_domain       
IPR009462   DUF1086       
IPR016197   Chromo-like_dom_sf       
IPR001965   Znf_PHD       
IPR013083   Znf_RING/FYVE/PHD       
IPR011011   Znf_FYVE_PHD       
IPR009463   DUF1087       
IPR036427   Bromodomain-like_sf       
IPR028727   CHD5       
IPR019786   Zinc_finger_PHD-type_CS       
IPR028725   CHD4       
IPR041565   Parkin_Znf-RING       
IPR000626   Ubiquitin_dom       
IPR041170   Znf-RING_14       
IPR003977   Parkin       
IPR002867   IBR_dom       
IPR001841   Znf_RING       
IPR029071   Ubiquitin-like_domsf       
SUPFAM
SSF54160   SSF54160        + More
SSF52540   SSF52540       
SSF57903   SSF57903       
SSF54236   SSF54236       
Gene 3D
PDB
3MWY     E-value=7.05613e-126,     Score=1160

Ontologies

Topology

Subcellular location
Nucleus  
Length:
1969
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.07905
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00000
outside
1  -  1969
 
 

Population Genetic Test Statistics

Pi
206.723246
Theta
167.04444
Tajima's D
0.576256
CLR
0.244891
CSRT
0.532623368831558
Interpretation
Uncertain
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