Gene

KWMTBOMO05874  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002939

Annotation

PREDICTED:_15-hydroxyprostaglandin_dehydrogenase_[NAD(+)]-like_[Bombyx_mori]

Location

Bomo_Chr10(-):13078792-13086570      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.496

CDS

ATGTCGCACGAATGGAAAGATAAAGTAGTTTTTATAACCGGTGCTGCAACGGGCATCGGTGAATCTGTGGTCAGGATATTATTAGACGAAGGAGTTAAGCATATAGCGATTTTGGACATCGCGGAAGAAGCCGGACAATCGTTACAAGCTGAACTGAATTCGAAATATGGCAACAAAACGAAGTTCTACAGGTCTGACGTCACTGATGAAGAGCACTTCCTGGGAATCCTTAACGCTGTAGTTCAGGAGCAAGGCGGCATTGATGTAGTGATTAATAATGCCGCCCTCATGAACGACAGTATTGGCATTTACAAAAAAGCCATTGAGGTCAACGTGACCGCCTTAATAACAAGTACATTAAAAGCCATTGAGATAATGGGGAAGCACAGCGGTGGTAAAGGAGGTACAGTTATCAACGTTTCTTCGGTTGCCGCTTTGACGCAATCTCACGTTATGCCAATATACTTCGCAACTAAAAGCGCTGTGCTGCAGTTCAGTAATTGTATCGGTAGACCGGAACACTTTTCGAAAACCGGGGTCCGAGTACTGACAGTGTGCTTTGGTGCAACAGACACCGCGTTGTTGACCGACGAGAAACTAGGCACTTTTGATAAGTACTTAGAATCTTCATGCTTGGACCAACTAAAGAAAGGCTTCATATTCCAACGCAAAGAATCCGCAGCTCAAGGCCTCGTTGATTCTTACAAGAAAGGTGAGAGTGGCAGTACATGGCTCGTTGTAAATAACTTGCCGGTTCAAGAGATCAGCGGGTCGGTCGCCGAAGCCTATCAGATTCTTTCTCAGAATGTTTATAGACTTTAA

Protein

MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRKESAAQGLVDSYKKGESGSTWLVVNNLPVQEISGSVAEAYQILSQNVYRL

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

H9J0A3   H9J0A5   H9J0A4   A0A3G1T1B2   A0A0H4TG49   A0A212F0I1   + More
A0A212F0G8   A0A194QE27   A0A194QRC6   A0A212F0G1   A0A076FT24   A0A0F6Q4J7   A0A1L8D6X2   A0A194Q8J5   A0A3S2PLF3   A0A194QQX1   A0A0L7KWX5   H9J0A6   H9J0A8   A0A3S2LVR9   A0A2W1BM47   A0A0L7KNY8   A0A212F0F9   A0A0L7KXH6   A0A3S2NMK6   A0A0L7KNH1   A0A0N0PD11   U5KCB3   A0A2H1VGZ5   A0A2H1VH14   A0A194QFX2   A0A2A4JLC0   A0A2W1BJY5   A0A2A4K9E1   A0A2H1VGZ4   H9J0A9   Q1G151   A0A194Q851   A0A194QQW0   A0A2H1WQ20   A0A0N1IPP9   A0A194QA61   A0A2H1WWP5   A0A194QA14   A0A0H4TY65   A0A2H1W7D8   A0A2A4JMW2   A0A2A4KAR2   A0A0F6Q2Y5   A0A2A4JMY9   A0A0N1PH34   A0A0N0PDG0   A0A224XI56   Q6RUR3   A0A026WRA5   A0A1Y1MAW1   A0A069DY58   A0A0J7L0X1   A0A0N0PD56   A0A067QWG1   A0A195E5P2   A0A023F7A3   F4W475   A0A151WLU8   E2A712   A0A026WSD7   H9JQQ4   A0A310S8E6   A0A195B3G3   A0A151X250   I6QWT6   A0A0L7QT43   A0A224XI78   A0A1W4X358   K7IV86   A0A195EUB2   A0A1W4XDZ2   A0A0L7L646   A0A194R4F0   A0A151XEI7   A0A195CJP6   G8JKE8   A0A0K8S9E4   A0A2J7QGZ8   A0A088A501   A0A0A9WS12   A0A232EGH1   A0A195ET92   A0A0J7L1B2   A0A212F936   E2B6N1   E0VAP2   E9I9W8   A0A154PC81   A0A158NDP0  

Pubmed

19121390    22118469    26354079    24817326    26227816    28756777    + More
24053512    24508170    30249741    28004739    26334808    24845553    25474469    21719571    20798317    20075255    22679863    25401762    26823975    28648823    20566863    21282665    21347285   

EMBL

BABH01019200    BABH01019208    BABH01019201    BABH01019202    MG846919    AXY94771.1    + More
KP899548    AKQ06147.1    AGBW02011082    OWR47240.1    OWR47239.1    KQ459302    KPJ01716.1    KQ461175    KPJ07894.1    OWR47236.1    KF960797    AII21999.1    KP237895    AKD01748.1    GEYN01000012    JAV02117.1    KPJ01719.1    RSAL01000003    RVE54802.1    KPJ07892.1    JTDY01004799    KOB67737.1    BABH01019209    BABH01019210    RVE54801.1    KZ149998    PZC75361.1    JTDY01007982    KOB64820.1    OWR47238.1    KOB67739.1    RVE54803.1    JTDY01007968    KOB64832.1    KQ460366    KPJ15584.1    KC007341    AGQ45606.1    ODYU01002522    SOQ40120.1    SOQ40118.1    KQ459249    KPJ02346.1    NWSH01001071    PCG72771.1    PZC75359.1    NWSH01000014    PCG80831.1    SOQ40119.1    BABH01019219    DQ512730    ABF59817.1    KPJ01717.1    KPJ07893.1    ODYU01010208    SOQ55170.1    KPJ15603.1    KPJ02362.1    ODYU01011579    SOQ57407.1    KPJ02363.1    KP899552    AKQ06151.1    ODYU01006680    SOQ48742.1    PCG72773.1    PCG80830.1    KP237897    AKD01750.1    PCG72772.1    KPJ15583.1    KPJ15602.1    GFTR01004259    JAW12167.1    AY491503    AAR84629.1    KK107119    QOIP01000009    EZA58570.1    RLU18591.1    GEZM01036109    GEZM01036108    JAV82969.1    GBGD01002580    JAC86309.1    LBMM01001364    KMQ96442.1    KPJ15601.1    KK852879    KDR14474.1    KQ979609    KYN20169.1    GBBI01001633    JAC17079.1    GL887491    EGI71071.1    KQ982944    KYQ48859.1    GL437252    EFN70744.1    EZA58571.1    RLU18590.1    BABH01012284    BABH01012285    KQ771134    OAD52541.1    KQ976625    KYM79033.1    KQ982585    KYQ54300.1    JQ398675    AFM38190.1    KQ414755    KOC61724.1    GFTR01004241    JAW12185.1    AAZX01008191    KQ981979    KYN31469.1    JTDY01002703    KOB70885.1    KQ460779    KPJ12399.1    KQ982254    KYQ58773.1    KQ977642    KYN00938.1    JP593077    AER92462.1    GBRD01015928    JAG49898.1    NEVH01014359    PNF27833.1    GBHO01034331    GDHC01017826    JAG09273.1    JAQ00803.1    NNAY01004765    OXU17447.1    KYN31470.1    KMQ96441.1    AGBW02009651    OWR50237.1    GL446000    EFN88615.1    DS235012    EEB10448.1    GL761846    EFZ22664.1    KQ434870    KZC09506.1    ADTU01012731   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000283053    UP000037510    + More
UP000218220    UP000053097    UP000279307    UP000036403    UP000027135    UP000078492    UP000007755    UP000075809    UP000000311    UP000078540    UP000053825    UP000192223    UP000002358    UP000078541    UP000078542    UP000235965    UP000005203    UP000215335    UP000008237    UP000009046    UP000076502    UP000005205   

PRIDE

H9J0A3    H9J0A5    H9J0A4    H9J0A6    H9J0A8    H9J0A9    + More
Q1G151    H9JQQ4   

Pfam

PF00106   adh_short        + More
PF10545   MADF_DNA_bdg

Interpro

IPR002347   SDR_fam        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR020904   Sc_DH/Rdtase_CS       
IPR006578   MADF-dom       

SUPFAM

SSF51735   SSF51735       

ProteinModelPortal

H9J0A3   H9J0A5   H9J0A4   A0A3G1T1B2   A0A0H4TG49   A0A212F0I1   + More
A0A212F0G8   A0A194QE27   A0A194QRC6   A0A212F0G1   A0A076FT24   A0A0F6Q4J7   A0A1L8D6X2   A0A194Q8J5   A0A3S2PLF3   A0A194QQX1   A0A0L7KWX5   H9J0A6   H9J0A8   A0A3S2LVR9   A0A2W1BM47   A0A0L7KNY8   A0A212F0F9   A0A0L7KXH6   A0A3S2NMK6   A0A0L7KNH1   A0A0N0PD11   U5KCB3   A0A2H1VGZ5   A0A2H1VH14   A0A194QFX2   A0A2A4JLC0   A0A2W1BJY5   A0A2A4K9E1   A0A2H1VGZ4   H9J0A9   Q1G151   A0A194Q851   A0A194QQW0   A0A2H1WQ20   A0A0N1IPP9   A0A194QA61   A0A2H1WWP5   A0A194QA14   A0A0H4TY65   A0A2H1W7D8   A0A2A4JMW2   A0A2A4KAR2   A0A0F6Q2Y5   A0A2A4JMY9   A0A0N1PH34   A0A0N0PDG0   A0A224XI56   Q6RUR3   A0A026WRA5   A0A1Y1MAW1   A0A069DY58   A0A0J7L0X1   A0A0N0PD56   A0A067QWG1   A0A195E5P2   A0A023F7A3   F4W475   A0A151WLU8   E2A712   A0A026WSD7   H9JQQ4   A0A310S8E6   A0A195B3G3   A0A151X250   I6QWT6   A0A0L7QT43   A0A224XI78   A0A1W4X358   K7IV86   A0A195EUB2   A0A1W4XDZ2   A0A0L7L646   A0A194R4F0   A0A151XEI7   A0A195CJP6   G8JKE8   A0A0K8S9E4   A0A2J7QGZ8   A0A088A501   A0A0A9WS12   A0A232EGH1   A0A195ET92   A0A0J7L1B2   A0A212F936   E2B6N1   E0VAP2   E9I9W8   A0A154PC81   A0A158NDP0  

PDB

2GDZ     E-value=4.84231e-26,     Score=291

KEGG

101746224    K00069 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] | (RefSeq) 15-hydroxyprostaglandin

GO

GO:0016491   GO:0004022   GO:0016404  

Length:

273

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.75598

Exp number, first 60 AAs:

1.49556

Total prob of N-in:

0.15443

outside

1  -  273

 

 

Pi

182.331363

Theta

170.838367

Tajima's D

0.533114

CLR

0.444464

CSRT

0.518574071296435

Interpretation

Uncertain