Gene

KWMTBOMO05845  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006959

Annotation

PREDICTED:_armadillo_segment_polarity_protein_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr10(+):12120931-12134204      View in EpiBrowser

Full name

Armadillo segment polarity protein      

Location in the cell

Cytoplasmic   Reliability : 1.708

CDS

ATGAGTTATCAAATTCCATCATCGCAAAGTCGCACAATGTCGCACAGCAGCTATGTTGCTTCTGATGTGCCAATGGCACCAAACAAAGAGCAGCAGACATTGATGTGGCAGCAAAACTCCTATTTAGTGGACTCTGGAATCAACTCTGGAGCTGCTACCCAGGTTCCATCACTAACTGGCAAGGAAGATGATGAGATGGAAGGTGACCAACTTATGTTTGACCTTGATCAGGGTTTTGCTCAGGGATTCACTCAAGAACAAGTTGATGATATGAATCAACAGCTTTCTCAAACTAGATCTCAAAGAGTCCGTGCGGCTATGTTTCCTGAAACGCTGGAGGAAGGAATTGAAATTCCATCGACACAGCTGGATCCCGCTCAACCAACTGCTGTCCAGCGTTTAGCTGAACCTTCCCAGATGTTAAAGCATGCTGTGGTGAACCTCATCAATTATCAAGATGATGCTGATTTAGCTACCAGAGCTATTCCAGAGTTGATAAAGCTACTGAATGATGAAGATCAAGTAGTAGTATCCCAAGCTGCCATGATGGTGCATCAGCTCTCTAAGAAGGAAGCATCGCGTCACGCCATTATGAACTCGCCACAAATGGTGGCTGCGTTGGTTCGCGCAATTTCCAACAGCAATGATCTAGAAACTACTAAGGGGGCAGTTGGCACCTTACACAATTTATCTCACCATCGTCAAGGTCTGCTTGCCATCTTCAAGAGTGGTGGAATTCCAGCATTAGTGAAACTACTCAGCTCTCCAGTTGAAGCTGTGCTCTTTTATGCTATTACAACACTGCATAACCTATTGTTGCATCAAGACGGTTCAAAGATGGCTGTTCGTCTAGCTGGAGGTCTACAAAAAATGGTGGCATTACTACAAAGGAACAATGTCAAGTTCCTAGCTATTGTGACTGACTGCCTTCAGATTTTGGCCTATGGGAATCAAGAATCGAAATTGATTATTCTAGCATCTCAGGGCCCAATCGAATTAGTTCGCATTATGCGTTCTTACGATTACGAAAAGTTGCTGTGGACAACTTCGAGAGTTCTTAAGGTATTATCGGTATGCTCAAGCAACAAGCCAGCTATAGTGGAAGCTGGTGGCATGCAAGCTCTGGCCATGCATCTAGGCAACCCGAGCGGCCGTCTCGTCCAGAACTGCCTTTGGACTCTGAGGAATCTGTCTGATGCTGCTACCAAAGTGGAAGGCCTGGAGGCATTGCTGCAAAGCCTCGTGCAAGTTCTAGCTTCGACTGATGTCAACATCGTGACCTGTGCTGCTGGAATTCTCTCCAACTTGACTTGCAACAACCAACGCAATAAGATGACGGTATGCCAGGTGGGCGGCGTGGACGCGCTGGTCCGCACGGTGGTGTCGGCCGGGGACCGCGAGGAGATCACGGAGCCCGCCATCTGTGCGCTGCGACACCTCACCTCCAGGCATGACGACAGTGAGATGGCGCAGAATGCAGTACGCCTGCATTATGGATTGCCGGTGATAGTGAAGCTGCTACAGCCTCCTTCTCGCTGGCCTCTAGTGAAGGCCGTCGTGGGCTTGGTACGCAACCTGGCGCTCTGCTCCGCCAACTACGCTCCGTTGCGGGAACATGGCGCCGTTCATCATCTGGTGCGCCTGCTGATGCGTGCCTACAACGACACCCAGAGACAACGCAGCTCTTCGGGCGGTGGAGCCAATACTGCTTACGCTGACGGCGTTCGTATGGAGGAGATCGTGGAAGGCGCCGTTGGAGCCTTGCATATTTTAGCCAAAGAAAGCCACAACAGACAACTTATCCGACAGCAGAACGTCATTCCGATATTCGTGCAACTGTTGTTCAATGAGATTGAAAATATTCAGCGCGTTGCCGCCGGCGTGCTCTGTGAATTGGCCGTAGAGAAAGAAGGAGCAGAAATGATCGAAGCCGAAGGGGCAACCGCTCCGCTCACTGAATTGCTGCATTCAAGAAATGAAGGGGTCGCCACGTACGCTGCAGCCGTTCTGTTCCGCATGTCCGAAGACAAGCCCCACGATTACAAGAAGAGACTCTCTATGGAATTGACTAATTCGTTGTTCCGCGACGATCACCAGATGTGGTCCAATGACCTTCCGATACAATCCGATATACAGGACATGCTCGGGCCAGAGCAGGGTTACGAGGGCCTGTATGGGACCAGACCATCCTTTCACCAACAAGGCTACGATCAAATACCGATAGATTCGATGCAGGGGCTTGAGATCGGTAGCGGTTTTGGTATGGACATGGACATTGGCGAGGCGGAAGGCGCGGGCGCGGCGTCAGCTGACCTGGCCTTCCCCGAGCCACCCCACGACAACAACAATGTGGCAGCCTGGTACGACACAGACCTTTAA

Protein

MSYQIPSSQSRTMSHSSYVASDVPMAPNKEQQTLMWQQNSYLVDSGINSGAATQVPSLTGKEDDEMEGDQLMFDLDQGFAQGFTQEQVDDMNQQLSQTRSQRVRAAMFPETLEEGIEIPSTQLDPAQPTAVQRLAEPSQMLKHAVVNLINYQDDADLATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLETTKGAVGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVEAVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVALLQRNNVKFLAIVTDCLQILAYGNQESKLIILASQGPIELVRIMRSYDYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALAMHLGNPSGRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQVLASTDVNIVTCAAGILSNLTCNNQRNKMTVCQVGGVDALVRTVVSAGDREEITEPAICALRHLTSRHDDSEMAQNAVRLHYGLPVIVKLLQPPSRWPLVKAVVGLVRNLALCSANYAPLREHGAVHHLVRLLMRAYNDTQRQRSSSGGGANTAYADGVRMEEIVEGAVGALHILAKESHNRQLIRQQNVIPIFVQLLFNEIENIQRVAAGVLCELAVEKEGAEMIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPHDYKKRLSMELTNSLFRDDHQMWSNDLPIQSDIQDMLGPEQGYEGLYGTRPSFHQQGYDQIPIDSMQGLEIGSGFGMDMDIGEAEGAGAASADLAFPEPPHDNNNVAAWYDTDL

Description

Isoform neural may associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Isoform cytoplasmic accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis.
May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis (By similarity).

Subunit

Interacts with Mer and Moe at the adherens junction (PubMed:8666669). Interacts with Inx2 (PubMed:15047872). Interacts with alpha-Cat (PubMed:25653389). Interacts with Myo31DF (PubMed:16598259, PubMed:22491943).
Interacts with Mer and Moe at the adherens junction.

Similarity

Belongs to the beta-catenin family.

Keywords

Alternative splicing   Cell adhesion   Cell junction   Cell membrane   Complete proteome   Cytoplasm   Developmental protein   Membrane   Phosphoprotein   Reference proteome   Repeat   Segmentation polarity protein   Wnt signaling pathway  

Feature

chain  Armadillo segment polarity protein
splice variant  In isoform Neural.

Uniprot

H9JBR4   A0A2H1WLR9   A0A3S2NML4   X2L6G3   A0A194QE46   A0A212F6N0   + More
A0A194QQU0   E2B7R3   A0A1L8DMB5   E2BXN9   E2AZN9   A0A0C9RQG9   A0A0L0C373   A0A0A1WGQ3   A0A026WDG5   A0A3B0KVR9   A0A1I8PYB0   A0A1I8PYE2   W8ASL5   A0A1W4VSQ9   B4M333   K7J6I5   M9PGG4   B3P8S9   P18824   A0A034VUY2   A0A0K8U2B4   B3MXH2   B4N1V6   A0A158ND49   B4JWY3   A0A3L8E4M5   A0A2A3E2T1   A0A088ASV7   A0A232EPB5   T1PFC0   A0A151X3X9   A0A195DUF5   F4X7D1   A0A195BNB7   A0A195F7X9   A0A0M4EUK6   Q02453   A0A151I8E6   A0A0M4ESV3   T1HHR2   A0A023F5L4   A0A1Y1NCG6   A0A069DWH2   A0A154PF68   A0A0T6AU15   A0A1B0DKX3   A0A0L7R6W9   A0A146L5T1   D3TLQ8   A0A336M2A0   Q29I35   Q76CZ7   A0A2J7QDQ0   D6X202   A0A1A9VD85   A0A067QTQ8   Q7QHW5   E0V8W8   A0A1B6C185   A0A2M4A3U4   A0A2M3Z1N7   A0A2M4BDL7   A0A2M4A3V6   Q17GS9   A0A2M4CUX6   A0A2M4A3R4   A0A2M4A3L0   E0V8X0   A0A182FIY5   A0A0C9RCC0   A0A0A1X9P9   A0A0K8V7Z9   A0A1I8PYE7   W8BQR6   A0A182U3Z2   A0A182P393   A0A0K8W0W9   A0A182Y567   A0A1L8DLC2   A0A088AVH5   A0A182GGV2   A0A0P6IJT4   U5EXF9   A0A1J1J1N0   A0A067QU74   A0A182RHI9   B0WHS4   A0A182W5J9   A0A084VLT8   A0A182GBL0   A0A1Q3FFC2   P18824-2   A0A1W4VS30   A0A3B0K6X4  

Pubmed

19121390    25038464    26354079    22118469    20798317    26108605    + More
25830018    24508170    24495485    17994087    18057021    20075255    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    2707602    9635189    10731137    12537569    7529201    8666669    11927557    15047872    16598259    18327897    22491943    25653389    25348373    21347285    30249741    28648823    21719571    8483160    25474469    28004739    26334808    26823975    20353571    15632085    18362917    19820115    24845553    12364791    20566863    17510324    25244985    26483478    24438588   

EMBL

BABH01024557    BABH01024558    ODYU01009524    SOQ54020.1    RSAL01000003    RVE54822.1    + More
KJ206237    AHN95656.1    KQ459302    KPJ01736.1    AGBW02010000    OWR49369.1    KQ461175    KPJ07873.1    GL446201    EFN88276.1    GFDF01006569    JAV07515.1    GL451281    EFN79557.1    GL444275    EFN61098.1    GBYB01010740    JAG80507.1    JRES01001065    KNC25859.1    GBXI01016225    JAC98066.1    KK107260    EZA54105.1    OUUW01000042    SPP89966.1    GAMC01014690    JAB91865.1    CH940651    EDW65208.1    KRF82078.1    KRF82079.1    AE014298    AGB94995.1    CH954183    EDV45534.1    KQS26004.1    KQS26006.1    KQS26007.1    X54468    AF001213    AL021106    AL021086    AY118525    GAKP01012733    JAC46219.1    GDHF01031839    GDHF01013604    GDHF01010197    GDHF01000012    JAI20475.1    JAI38710.1    JAI42117.1    JAI52302.1    CH902630    EDV38437.1    CH963925    EDW78345.1    KRF98857.1    ADTU01012387    CH916376    EDV95259.1    QOIP01000001    RLU27641.1    KZ288418    PBC26015.1    NNAY01002985    OXU20172.1    KA646865    AFP61494.1    KQ982554    KYQ55126.1    KQ980341    KYN16392.1    GL888828    EGI57743.1    KQ976438    KYM86857.1    KQ981744    KYN36486.1    CP012528    ALC49451.1    L04874    KQ978377    KYM94561.1    ALC49452.1    ACPB03000442    GBBI01002258    JAC16454.1    GEZM01006917    JAV95573.1    GBGD01000511    JAC88378.1    KQ434890    KZC10491.1    LJIG01022843    KRT78429.1    AJVK01006519    KQ414646    KOC66593.1    GDHC01016122    JAQ02507.1    CCAG010022197    EZ422360    ADD18636.1    UFQT01000445    SSX24365.1    CH379064    AB109212    BAD00045.1    NEVH01015817    PNF26703.1    KQ971371    EFA10737.2    KK852946    KDR13423.1    AAAB01008811    DS234986    EEB09824.1    GEDC01030303    GEDC01005515    JAS06995.1    JAS31783.1    GGFK01002071    MBW35392.1    GGFM01001675    MBW22426.1    GGFJ01002009    MBW51150.1    GGFK01002089    MBW35410.1    CH477256    EAT45858.1    GGFL01004460    MBW68638.1    GGFK01002078    MBW35399.1    GGFK01002072    MBW35393.1    EEB09826.1    GBYB01010742    JAG80509.1    GBXI01006263    JAD08029.1    GDHF01017257    GDHF01010333    GDHF01006251    JAI35057.1    JAI41981.1    JAI46063.1    GAMC01014691    JAB91864.1    GDHF01021598    GDHF01019605    GDHF01007595    JAI30716.1    JAI32709.1    JAI44719.1    GFDF01006828    JAV07256.1    JXUM01062538    JXUM01062539    JXUM01062540    JXUM01062541    JXUM01062542    KQ562204    KXJ76424.1    GDIQ01003271    JAN91466.1    GANO01000970    JAB58901.1    CVRI01000063    CRL04769.1    KDR13424.1    DS231939    EDS27941.1    ATLV01014553    ATLV01014554    KE524974    KFB38932.1    JXUM01052918    KQ561755    KXJ77622.1    GFDL01008843    JAV26202.1    SPP89967.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000007151    UP000053240    UP000008237    + More
UP000000311    UP000037069    UP000053097    UP000268350    UP000095300    UP000192221    UP000008792    UP000002358    UP000000803    UP000008711    UP000007801    UP000007798    UP000005205    UP000001070    UP000279307    UP000242457    UP000005203    UP000215335    UP000075809    UP000078492    UP000007755    UP000078540    UP000078541    UP000092553    UP000095301    UP000078542    UP000015103    UP000076502    UP000092462    UP000053825    UP000092444    UP000001819    UP000235965    UP000007266    UP000078200    UP000027135    UP000007062    UP000009046    UP000008820    UP000069272    UP000075902    UP000075885    UP000076408    UP000069940    UP000249989    UP000183832    UP000075900    UP000002320    UP000075920    UP000030765   

PRIDE

H9JBR4    M9PGG4    P18824    Q02453    Q29I35    Q7QHW5    + More
Q17GS9   

Pfam

PF00514   Arm        + More
PF15917   PIEZO
PF12166   Piezo_RRas_bdg

Interpro

IPR016024   ARM-type_fold        + More
IPR011989   ARM-like       
IPR000225   Armadillo       
IPR013284   Beta-catenin       
IPR027272   Piezo       
IPR031334   Piezo_RRas-bd_dom       
IPR031805   Piezo_dom       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

H9JBR4   A0A2H1WLR9   A0A3S2NML4   X2L6G3   A0A194QE46   A0A212F6N0   + More
A0A194QQU0   E2B7R3   A0A1L8DMB5   E2BXN9   E2AZN9   A0A0C9RQG9   A0A0L0C373   A0A0A1WGQ3   A0A026WDG5   A0A3B0KVR9   A0A1I8PYB0   A0A1I8PYE2   W8ASL5   A0A1W4VSQ9   B4M333   K7J6I5   M9PGG4   B3P8S9   P18824   A0A034VUY2   A0A0K8U2B4   B3MXH2   B4N1V6   A0A158ND49   B4JWY3   A0A3L8E4M5   A0A2A3E2T1   A0A088ASV7   A0A232EPB5   T1PFC0   A0A151X3X9   A0A195DUF5   F4X7D1   A0A195BNB7   A0A195F7X9   A0A0M4EUK6   Q02453   A0A151I8E6   A0A0M4ESV3   T1HHR2   A0A023F5L4   A0A1Y1NCG6   A0A069DWH2   A0A154PF68   A0A0T6AU15   A0A1B0DKX3   A0A0L7R6W9   A0A146L5T1   D3TLQ8   A0A336M2A0   Q29I35   Q76CZ7   A0A2J7QDQ0   D6X202   A0A1A9VD85   A0A067QTQ8   Q7QHW5   E0V8W8   A0A1B6C185   A0A2M4A3U4   A0A2M3Z1N7   A0A2M4BDL7   A0A2M4A3V6   Q17GS9   A0A2M4CUX6   A0A2M4A3R4   A0A2M4A3L0   E0V8X0   A0A182FIY5   A0A0C9RCC0   A0A0A1X9P9   A0A0K8V7Z9   A0A1I8PYE7   W8BQR6   A0A182U3Z2   A0A182P393   A0A0K8W0W9   A0A182Y567   A0A1L8DLC2   A0A088AVH5   A0A182GGV2   A0A0P6IJT4   U5EXF9   A0A1J1J1N0   A0A067QU74   A0A182RHI9   B0WHS4   A0A182W5J9   A0A084VLT8   A0A182GBL0   A0A1Q3FFC2   P18824-2   A0A1W4VS30   A0A3B0K6X4  

PDB

2Z6G     E-value=0,     Score=2599

KEGG

101744450    K02105 catenin beta 1 | (RefSeq) armadillo segment polarity protein

PATHWAY

04310    Wnt signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0045296   GO:0007155   GO:0007616   GO:0045186   GO:0019900   GO:0030424   GO:0035147   GO:0035153   GO:0005915   GO:0030139   GO:0090254   GO:0035019   GO:0048526   GO:0060914   GO:0046530   GO:0007391   GO:1990907   GO:0007370   GO:0048477   GO:0045944   GO:0072659   GO:0046667   GO:0003713   GO:0014019   GO:0008134   GO:0000122   GO:0001709   GO:0007367   GO:0060070   GO:0060232   GO:0071896   GO:0016324   GO:0016342   GO:0035293   GO:0008587   GO:0098609   GO:0007472   GO:0005912   GO:0007399   GO:0000902   GO:0001745   GO:0005886   GO:0048754   GO:0035017   GO:0045893   GO:0014017   GO:0005829   GO:0005654   GO:0007507   GO:0005634   GO:0005737   GO:0016055   GO:0045294   GO:0019903   GO:0005913   GO:0035257   GO:0016021   GO:0008381   GO:0005515   GO:0005488   GO:0004871   GO:0008270   GO:0051287   GO:0005216   GO:0006811   GO:0006541   GO:0016812   GO:0016597  

PANTHER

PTHR13167  

Subcellular location

Cytoplasm  
Cell membrane  
Cell junction  
Adherens junction  

Length:

792

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0664099999999999

Exp number, first 60 AAs:

0.00017

Total prob of N-in:

0.00133

outside

1  -  792

 

 

Pi

255.040805

Theta

186.891032

Tajima's D

1.034109

CLR

0.118261

CSRT

0.666516674166292

Interpretation

Uncertain