Gene

KWMTBOMO05818  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006908

Annotation

PREDICTED:_low-density_lipoprotein_receptor-related_protein_2_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr10(-):10743994-10788130      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 4.181

CDS

ATGAACGTCAAATCAAGCACTATAATGTACTTACTATGGTTCGCCTTATTTATTGTGATGATTTCACAAGCCGATGCGTCAATATTGGGTTCTCATTGTCGAAGCAATGCGGACTGTAAAGTGGCCTATGCTCATTGTGACAGAGGAATGTGCATGTGTCAGCCCTATTACGCTCGCGTTGATAACTCCACCTGCTTGGAATCAACTCTACTTGGTTCAGAGTGCATGGTGGCTGAACAGTGCACGCAGAAAGTGGCTTACAGCGCATGCTTGGAAGGCGTTTGCCGTTGTACAGACGGACACCTACAATTTAGAAAACACACTTGCCTATCCCCTGCTCCGCCTGGTCACGTTTGCTACAGTAATGAACATTGTCGGTTATGGGATAAGGAAAGCCGATGCGAATTCGTGATTCTTAATCTATTCGGGAGATGCGCTTGCAATTCCTACTATAAACAAAATGGCGATAAATGTGTGCTCTCGAAGATTTCCCCCTATGCAACCGAAGCAGTGATCGCAGAACAAGATTCCGCTCTGAGTCCTATGAATGGCCCTCAAAATACGATGAATAGTAATGGCCAGACTTCCTTCAGCGCTGAGTCAGGATTTAATGAGAGAAACCAGGCTCGACCAAGCAAAACTCCCATATTTTCCGATAATGATGTTTTGAGTACAGAAGACGATAATCTATTAATGCAAGCCGTATTGAAGGTGCCAACTATAGAACCAGCCAAAAAATTACCTGTCTCTAACAGAAAAGAGGGCGAACCAAATGAGACAGTTGGTGTTAATGAAATGACTGCAAACTTGCATGCAAACGATCAGCCTGTTTACAGGGTTGTGACGCAACCAACAGTAGATAAAAAGTCTAATAAGAAGACAGGGTCCACAAAAGAAACTTCAGAAGGTAAACCGCACAAAACTGGACATCAAAAAAAATCATCTCTCAAGGATAAGCAACGCATTCGCACTGATGTCTCTGGCGACCTTGGACCTTCATCTCTAGGTATGCCTTGTATGACAGACGCACAATGCCATCTAGTGGATCCTCATACGAAATGCTTAAACAAACGATGTGATTGCGCTCATCGCACTAATTCGACATCAGCTTGTTCGGCTCGCAACAGGGGCTGCTTACCTGGAACATTTCAATGTCGGTCTACGGGCACCTGCATAAGCTGGTACTTCGTCTGTGATGGGCGTAAGGATTGTTCTGATGGATCCGATGAGAAGTGTCAAGATGGGACGGGCGAGCGGTGTCCTATGAACTCGTTCAGATGTGGGGGTCCTGGTTCGCCGTGTGTATCAAGGGCGGCCAGGTGTGATGGCACTCCACAGTGTCCCGGAGGCGAAGATGAAAGAAACTGTAAGGCGACGAGACGCAGGGGATGTCCCCGTCACACGTTCCGTTGCGGTTCTGGTGAATGTTTACCGGAGTACGAGTTTTGTAACGCTATAATATCATGCAAAGACGCTTCTGATGAACCACCACATTTATGTACAGAACAATCAAGATGGCGAGCCGCTGATTTCTGCCCTCTTCGATGTGGCAATGGCCGTTGCAGAAGCACAGCCGTAGCATGTTCAGGACGCGACGGGTGTGGAGATAACAGCGATGAAATTGCATGTTCTGTTTGTAAGTGTCCATCGCCTCAGACGCCTTGA

Protein

MNVKSSTIMYLLWFALFIVMISQADASILGSHCRSNADCKVAYAHCDRGMCMCQPYYARVDNSTCLESTLLGSECMVAEQCTQKVAYSACLEGVCRCTDGHLQFRKHTCLSPAPPGHVCYSNEHCRLWDKESRCEFVILNLFGRCACNSYYKQNGDKCVLSKISPYATEAVIAEQDSALSPMNGPQNTMNSNGQTSFSAESGFNERNQARPSKTPIFSDNDVLSTEDDNLLMQAVLKVPTIEPAKKLPVSNRKEGEPNETVGVNEMTANLHANDQPVYRVVTQPTVDKKSNKKTGSTKETSEGKPHKTGHQKKSSLKDKQRIRTDVSGDLGPSSLGMPCMTDAQCHLVDPHTKCLNKRCDCAHRTNSTSACSARNRGCLPGTFQCRSTGTCISWYFVCDGRKDCSDGSDEKCQDGTGERCPMNSFRCGGPGSPCVSRAARCDGTPQCPGGEDERNCKATRRRGCPRHTFRCGSGECLPEYEFCNAIISCKDASDEPPHLCTEQSRWRAADFCPLRCGNGRCRSTAVACSGRDGCGDNSDEIACSVCKCPSPQTP

Uniprot

H9JBL3   A0A2A4JS82   A0A194QS91   A0A194Q8B1   A0A212F110   A0A0L7LLJ7   + More
A0A158NPH2   A0A195E658   A0A151WR70   A0A026WH94   A0A195EUY8   K7IZ30   A0A0C9RG06   A0A195BA34   E2C919   E2ACT5   F4WNZ7   A0A195CP09   A0A067RA40   A0A1B6DKZ2   A0A0N0BJK5   A0A310S979   A0A2S2PS21   A0A087ZWI8   A0A2S2QTF5   X1WJM5   A0A154P0J9   A0A0A1XA81   A0A182Q8N0   A0A1J1ITD7   A0A0L0CR37   A0A0L7QVK5  

Pubmed

19121390    26354079    22118469    26227816    21347285    24508170    + More
20075255    20798317    21719571    24845553    25830018    26108605   

EMBL

BABH01024481    BABH01024482    NWSH01000730    PCG74548.1    KQ461175    KPJ07850.1    + More
KQ459302    KPJ01763.1    AGBW02011011    OWR47391.1    JTDY01000658    KOB76300.1    ADTU01022544    ADTU01022545    KQ979608    KYN20334.1    KQ982807    KYQ50399.1    KK107207    EZA55432.1    KQ981965    KYN31707.1    GBYB01007260    JAG77027.1    KQ976542    KYM81090.1    GL453768    EFN75555.1    GL438582    EFN68733.1    GL888243    EGI63928.1    KQ977574    KYN01844.1    KK852824    KDR15449.1    GEDC01010976    JAS26322.1    KQ435713    KOX79262.1    KQ763441    OAD55110.1    GGMR01019509    MBY32128.1    GGMS01011209    MBY80412.1    ABLF02017102    KQ434792    KZC05445.1    GBXI01006652    JAD07640.1    AXCN02000398    CVRI01000059    CRL03471.1    JRES01000036    KNC34711.1    KQ414727    KOC62589.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000005205    UP000078492    UP000075809    UP000053097    UP000078541    UP000002358    UP000078540    UP000008237    UP000000311    UP000007755    UP000078542    UP000027135    UP000053105    UP000005203    UP000007819    UP000076502    UP000075886    UP000183832    UP000037069    UP000053825   

PRIDE

H9JBL3   

Pfam

PF02995   DUF229        + More
PF00057   Ldl_recept_a
PF01683   EB

Interpro

IPR023415   LDLR_class-A_CS        + More
IPR017850   Alkaline_phosphatase_core_sf       
IPR004245   DUF229       
IPR002172   LDrepeatLR_classA_rpt       
IPR036055   LDL_receptor-like_sf       
IPR006149   EB_dom       

SUPFAM

SSF53649   SSF53649        + More
SSF57424   SSF57424       

Gene 3D

3.40.720.10     4.10.400.10    

CDD

cd00112  LDLa
cd16021  ALP_like

ProteinModelPortal

H9JBL3   A0A2A4JS82   A0A194QS91   A0A194Q8B1   A0A212F110   A0A0L7LLJ7   + More
A0A158NPH2   A0A195E658   A0A151WR70   A0A026WH94   A0A195EUY8   K7IZ30   A0A0C9RG06   A0A195BA34   E2C919   E2ACT5   F4WNZ7   A0A195CP09   A0A067RA40   A0A1B6DKZ2   A0A0N0BJK5   A0A310S979   A0A2S2PS21   A0A087ZWI8   A0A2S2QTF5   X1WJM5   A0A154P0J9   A0A0A1XA81   A0A182Q8N0   A0A1J1ITD7   A0A0L0CR37   A0A0L7QVK5  

PDB

3M0C     E-value=1.14669e-16,     Score=213

KEGG

101742529    no KO assigned | (RefSeq) low-density lipoprotein receptor-related protein 2

GO

GO:0003824   GO:0016021   GO:0005515   GO:0008152   GO:0004190   GO:0006508   GO:0015074   GO:0005216   GO:0006811   GO:0006541   GO:0016812   GO:0016597  

PANTHER

PTHR10974  

SignalP

Position:   1 - 26,         Likelihood:  0.998778

 

 

Length:

554

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.96415

Exp number, first 60 AAs:

18.96399

Total prob of N-in:

0.94332

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  24

outside

25  -  554

 

 

Pi

162.135056

Theta

160.029072

Tajima's D

0.252782

CLR

0.712795

CSRT

0.444827758612069

Interpretation

Uncertain