Gene

KWMTBOMO05804

Pre Gene Modal

BGIBMGA006912

Annotation

PREDICTED:_pleckstrin_homology_domain-containing_family_A_member_3-like_[Amyelois_transitella]

Location

Bomo_Chr10(-):10457923-10460040      View in EpiBrowser

Full name

Pleckstrin homology domain-containing family A member 3      

Alternative Name

Phosphatidylinositol-four-phosphate adapter protein 1

Location in the cell

Cytoplasmic   Reliability : 1.107 Extracellular   Reliability : 1.438 Nuclear   Reliability : 1.542

CDS

ATGGAGGGAGTTTTATGGAAATGGACAAATTATTGGAACGGATGGCAGACAAGATGGTTTGTGTTAGAGAATGGTATACTTTCTTATTATAAATCACAAGATGAAGTAGTTCAGGGATGTAAAGGATCAGTGAAAGTATCTGTTTGTCAAATAAATGTTAATACTATTGACAACACAAGATTGGATCTAGTGATACCAGGTCAACAGCATATGTACTTAAGGGCACCTTCTCCTCAAGATAGACAAAAATGGCTTGTGGCATTAGGAAGTGCCAAGGCATGTGTTGACGCACAAGATATAAAAGGTATAATCTTCGAGGATACAAATACTTTGAGTCATAAAAAATCTGAATTGCGTTTGTATTGTGATCTCATGATGCAGCAAGTTCATGCAGTGAAAAGTGCGGCAAATGCAGATACTGGTCCTGAATTACAGACTATTAATGATGCAACAAGTTTACTCACAGCAACGTGTGATACATTCATCAGAACGCTGGAAGATATAATGAAGCTTGCACCTCCAGGAGCTCCACCAACCACTCCATATGAAATGCCCATACCCAATTTAATAATCACAAAAAACAACTCTTCAAATAAAATGCCTAGACAATCACTAAGTAGAACTTTATCACAAGAGAATAGATGA

Protein

MEGVLWKWTNYWNGWQTRWFVLENGILSYYKSQDEVVQGCKGSVKVSVCQINVNTIDNTRLDLVIPGQQHMYLRAPSPQDRQKWLVALGSAKACVDAQDIKGIIFEDTNTLSHKKSELRLYCDLMMQQVHAVKSAANADTGPELQTINDATSLLTATCDTFIRTLEDIMKLAPPGAPPTTPYEMPIPNLIITKNNSSNKMPRQSLSRTLSQENR

Description

Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P) (By similarity).

Subunit

Interacts with GTP-bound ARF1.

Keywords

Complete proteome   Golgi apparatus   Lipid-binding   Membrane   Phosphoprotein   Reference proteome  

Feature

chain  Pleckstrin homology domain-containing family A member 3

Uniprot

H9JBL7   A0A2A4IVJ0   A0A2W1BY25   A0A2H1VKF6   A0A1E1WT83   A0A212EUT5   + More
S4PD53   A0A194QQR2   A0A194Q8B3   A0A0L7KYP4   A0A1Y1LYT4   A0A2P8Z6X4   A0A1W4WKR8   A0A2J7QTV7   A0A1B6MNV8   D6X1N8   A0A224XXZ3   A0A069DQR0   A0A0P4VJJ5   T1HTM9   A0A0V0G811   R4FKC3   A0A1B6C3E3   A0A1B6JPW5   N6UNY2   A0A3R7LZ98   E0V9Z6   E9G4D9   A0A0P5EAB2   A0A164ZA61   A0A0P6GVB3   A0A0P6AXC7   A0A023GFR4   A0A2I0UM07   A0A3Q0JE50   A0A1D2N572   A0A146L3F6   K7F4B6   A0A218V0C3   A0A2K6FU15   G1SP17   A0A0Q3X8C4   F7IGZ9   G3SY28   A0A2K5YAD8   A0A2K5PTM2   A0A1U7TKM7   Q5ZL31   A0A0P6J473   F6VUN2   A0A2Y9DIW1   A0A3L7HG67   F1P131   I3M7E9   A0A3L8SEV1   A0A2K5EG19   G3W995   H0WLC5   H9FYR4   H9ZCM1   A0A2K6U5Y6   V5IEA7   G7N8F0   A0A2K6JNM2   A0A2K6R2F2   H0V1Y4   A0A2K6ECE1   A0A0D9RNY0   A0A096N3X0   G7PKY0   H9FYR3   H9ZCM0   Q5XIC5   A0A151LZS0   A0A1U7SF69   A0A151LZV7   A0A1U7SQ72   A0A2K5N1S9   A0A1S3H6Z8   A0A3Q7ME12   L5K076   K9IIZ4   W5MGT8   A0A2U3W6L4   A0A2Y9I483   A0A2U3XP99   A0A2Y9IU98   M3XVM0   A0A226EX66   A0A1W7RER3   M3X8M4   A0A3Q7V7X7   E9PSY1   Q9ERS4   K1PRP9   H3A7R1   F6T027   A0A0P4WR52   A0A2Y9MTY7   A0A250YF06  

Pubmed

19121390    28756777    22118469    23622113    26354079    26227816    + More
28004739    29403074    18362917    19820115    26334808    27129103    23537049    20566863    21292972    27289101    26823975    17381049    21993624    25243066    15642098    17495919    29704459    15592404    30282656    21709235    25319552    25765539    22002653    25362486    17431167    15489334    22293439    26383154    23258410    26358130    17975172    15057822    11001876    22992520    9215903    19892987    28087693   

EMBL

BABH01024462    NWSH01006085    PCG63679.1    KZ149900    PZC78555.1    ODYU01003034    + More
SOQ41303.1    GDQN01000801    JAT90253.1    AGBW02012322    OWR45214.1    GAIX01003801    JAA88759.1    KQ461175    KPJ07837.1    KQ459302    KPJ01777.1    JTDY01004344    KOB68270.1    GEZM01044355    GEZM01044354    JAV78281.1    PYGN01000169    PSN52246.1    NEVH01011193    PNF32017.1    GEBQ01002384    JAT37593.1    KQ971370    EFA09354.1    GFTR01003525    JAW12901.1    GBGD01002917    JAC85972.1    GDKW01002224    JAI54371.1    ACPB03018756    GECL01002079    JAP04045.1    GAHY01001918    JAA75592.1    GEDC01029538    JAS07760.1    GECU01006408    JAT01299.1    APGK01002936    APGK01011044    KB738380    KB735037    KB630790    KB631809    ENN82629.1    ENN83460.1    ERL83871.1    ERL86338.1    QCYY01002823    ROT67298.1    DS235001    EEB10202.1    GL732532    EFX85278.1    GDIP01144404    JAJ78998.1    LRGB01000763    KZS16115.1    GDIQ01028722    JAN66015.1    GDIP01023363    JAM80352.1    GBBM01002512    JAC32906.1    KZ505689    PKU47081.1    LJIJ01000210    ODN00381.1    GDHC01017329    JAQ01300.1    AGCU01060209    MUZQ01000078    OWK59474.1    AAGW02003912    AAGW02003913    LMAW01000225    KQL59986.1    GAMT01000717    GAMS01009944    GAMR01005377    GAMQ01000869    GAMP01009460    JAB11144.1    JAB13192.1    JAB28555.1    JAB40982.1    JAB43295.1    AJ719903    CAG31562.1    GEBF01006394    JAN97238.1    RAZU01000230    RLQ64948.1    AADN05000350    AGTP01035640    QUSF01000024    RLW00951.1    AEFK01112676    AAQR03082689    AAQR03082690    AAQR03082691    AAQR03082692    AAQR03082693    JU336020    JV047993    AFE79773.1    AFI38064.1    JU476883    AFH33687.1    GANP01010517    JAB73951.1    CM001264    EHH21500.1    AAKN02005538    AQIB01009854    AHZZ02004181    AQIA01015137    CM001287    EHH54989.1    JSUE03009180    JSUE03009181    JU336019    JV043176    AFE79772.1    AFI33247.1    JU476882    AFH33686.1    BC083759    AAH83759.1    AKHW03006853    KYO17775.1    KYO17776.1    KB031068    ELK04747.1    GABZ01007198    JAA46327.1    AHAT01020123    AEYP01071568    AEYP01071569    AEYP01071570    LNIX01000001    OXA62182.1    GDAY02001798    JAV49634.1    AANG04001482    AABR07052585    AF286163    BC031110    JH819082    EKC21514.1    AFYH01244772    AFYH01244773    AFYH01244774    AFYH01244775    AFYH01244776    GDRN01045263    JAI66876.1    GFFW01002632    JAV42156.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000037510    + More
UP000245037    UP000192223    UP000235965    UP000007266    UP000015103    UP000019118    UP000030742    UP000283509    UP000009046    UP000000305    UP000076858    UP000079169    UP000094527    UP000007267    UP000197619    UP000233160    UP000001811    UP000051836    UP000008225    UP000007646    UP000233140    UP000233040    UP000189704    UP000002280    UP000248480    UP000273346    UP000000539    UP000005215    UP000276834    UP000233020    UP000007648    UP000005225    UP000233220    UP000233180    UP000233200    UP000005447    UP000233120    UP000029965    UP000028761    UP000009130    UP000233100    UP000006718    UP000050525    UP000189705    UP000233060    UP000085678    UP000286641    UP000010552    UP000018468    UP000245340    UP000248481    UP000245341    UP000248482    UP000000715    UP000198287    UP000011712    UP000286642    UP000002494    UP000000589    UP000005408    UP000008672    UP000002281    UP000248483   

PRIDE

H9JBL7    E9PSY1    Q9ERS4   

Pfam

PF00169   PH        + More
PF08718   GLTP

Interpro

IPR000648   Oxysterol-bd        + More
IPR001849   PH_domain       
IPR011993   PH-like_dom_sf       
IPR036497   GLTP_sf       
IPR014830   Glycolipid_transfer_prot_dom       

SUPFAM

SSF110004   SSF110004       

Gene 3D

2.30.29.30     1.10.3520.10    

ProteinModelPortal

H9JBL7   A0A2A4IVJ0   A0A2W1BY25   A0A2H1VKF6   A0A1E1WT83   A0A212EUT5   + More
S4PD53   A0A194QQR2   A0A194Q8B3   A0A0L7KYP4   A0A1Y1LYT4   A0A2P8Z6X4   A0A1W4WKR8   A0A2J7QTV7   A0A1B6MNV8   D6X1N8   A0A224XXZ3   A0A069DQR0   A0A0P4VJJ5   T1HTM9   A0A0V0G811   R4FKC3   A0A1B6C3E3   A0A1B6JPW5   N6UNY2   A0A3R7LZ98   E0V9Z6   E9G4D9   A0A0P5EAB2   A0A164ZA61   A0A0P6GVB3   A0A0P6AXC7   A0A023GFR4   A0A2I0UM07   A0A3Q0JE50   A0A1D2N572   A0A146L3F6   K7F4B6   A0A218V0C3   A0A2K6FU15   G1SP17   A0A0Q3X8C4   F7IGZ9   G3SY28   A0A2K5YAD8   A0A2K5PTM2   A0A1U7TKM7   Q5ZL31   A0A0P6J473   F6VUN2   A0A2Y9DIW1   A0A3L7HG67   F1P131   I3M7E9   A0A3L8SEV1   A0A2K5EG19   G3W995   H0WLC5   H9FYR4   H9ZCM1   A0A2K6U5Y6   V5IEA7   G7N8F0   A0A2K6JNM2   A0A2K6R2F2   H0V1Y4   A0A2K6ECE1   A0A0D9RNY0   A0A096N3X0   G7PKY0   H9FYR3   H9ZCM0   Q5XIC5   A0A151LZS0   A0A1U7SF69   A0A151LZV7   A0A1U7SQ72   A0A2K5N1S9   A0A1S3H6Z8   A0A3Q7ME12   L5K076   K9IIZ4   W5MGT8   A0A2U3W6L4   A0A2Y9I483   A0A2U3XP99   A0A2Y9IU98   M3XVM0   A0A226EX66   A0A1W7RER3   M3X8M4   A0A3Q7V7X7   E9PSY1   Q9ERS4   K1PRP9   H3A7R1   F6T027   A0A0P4WR52   A0A2Y9MTY7   A0A250YF06  

PDB

2MDX     E-value=6.97865e-36,     Score=374

KEGG

101741140    K08051 pleckstrin homology domain containing family A member 8 | (RefSeq) pleckstrin homology domain

GO

GO:0016740   GO:0005794   GO:0070273   GO:0008289   GO:0035621   GO:1902387   GO:1902388   GO:0120009   GO:0005829   GO:0035627   GO:0005737   GO:0120013   GO:0016020  

PANTHER

PTHR10972  

Subcellular location

  

Length:

214

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00412

Exp number, first 60 AAs:

0.0037

Total prob of N-in:

0.09850

outside

1  -  214

 

 

Pi

29.704974

Theta

48.265666

Tajima's D

-1.482583

CLR

0.845113

CSRT

0.0620968951552422

Interpretation

Uncertain