Gene

KWMTBOMO05792

Annotation

PREDICTED:_transmembrane_protein_17-like_[Amyelois_transitella]

Location

Bomo_Chr10(+):10161056-10162157      View in EpiBrowser

Full name

Transmembrane protein 17B       + More
Transmembrane protein 17      

Location in the cell

PlasmaMembrane   Reliability : 3.479

CDS

ATGAAGTTTGATCAACTTAGCCACCTGACAAAATACTTATCAGCTACAGTTTTTTTGCTACTATCTGGAATAGAAATTGTACGATTGTACCTTGGTAGATATGGAAATTTGTCTTGCAGAGTTCCAGAATTAGCTGTATTCCTCATGTTGACAATTTTAATGCAAATGCCACTAGTTAGCTTCTTCCTTTTTCATCCATATTTGCTGAGTACACCAACAGAAATAACGCTGCATGCTATGTTTTGGATGACTACTATTATTGAGATTGTGTACGGGTTTAGAGCATTAAAACAAGCTTCTTCTCTAGCTAAAAGCATTTACCTGTCCACAACTCAGAATCAGTGA

Protein

MKFDQLSHLTKYLSATVFLLLSGIEIVRLYLGRYGNLSCRVPELAVFLMLTILMQMPLVSFFLFHPYLLSTPTEITLHAMFWMTTIIEIVYGFRALKQASSLAKSIYLSTTQNQ

Description

Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).

Subunit

Part of the tectonic-like complex (also named B9 complex).

Similarity

Belongs to the TMEM17 family.

Keywords

Cell membrane   Cell projection   Cilium   Complete proteome   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Transmembrane protein 17B

Uniprot

A0A2H1WH09   S4PG27   W4YUN2   A0A3Q3KRW7   A5D6V4   A0A1A7XGV2   + More
A0A1A7YWZ3   A0A0P7UHE5   A0A3Q2CB98   A0A1W4Z510   A0A2J7Q894   A0A3Q0SPR2   E0W0I0   A0A3P9CM18   A0A3Q4HAI6   A0A3P8NM58   A0A3B4H0K9   A0A3Q3BSX2   I3JWC7   A0A1B6CYK2   A0A3Q3JHY9   A0A2A3E9I7   A0A3Q1J2Y8   A0A267G9J1   A7SAJ8   A0A3Q3EBU9   C1C4N8   A0A2G9REA2   A0A093RBM7   A0A0L8FNL4   A0A3B4XD07   A0A3B4VD05   A0A0L8FNP4   A0A267FQM5   A0A0N0BC31   A0A0L7R6W0   A0A183QJ43   A0A3P9KHC8   A0A3Q2ZE67   G4VHQ1   A0A0F8AQ26   A0A267GWU3   V9LIH1   A0A0K2U623   A0A095A273   A0A1V4IFI8   G3PB05   G3PA66   A0A1A8SB05   A0A1A8DHF3   A0A1A8EUN8   A0A1A8JL64   A0A1A8ULK4   A0A1A8NET5   A0A1A8NDT8   A0A1A8CMF5   A0A091QFJ0   A0A091HM53   A0A3P9JTI2   H2MPJ7   H0YVH1   G3WMS7   A0A218UI63   C3YCS9   A0A093IVV9   H0YVH2   A0A3Q1BPJ9   A0A2I4AZZ2   A0A3Q1FZU6   A0A3L8SR47   A0A3B4ZKB1   A0A3P8SQT8   A0A091FR51   G1N0B1   A0A1U7RPW8   A0A3P8WHV9   A0A3B1K9A1   A0A3Q1GQ30   A0A2I0LT41   A0A0E9WXH6   A0A3Q1BTW8   A0A3P8SVP9   A0A091E9J2   A0A3M0K3S0   A0A2G8K990   E1BY51   A0A2P4SVV4   A0A2D0SCL2   A0A091WD82   A0A2D4NMQ0   K7G340   A0A3P8XDB2   A0A226N553   A0A091KH45   A0A226PRX2   A0A3B4CF32   K1QD50   A0A1S3KPQ0  

Pubmed

23622113    23594743    20566863    25186727    17615350    17554307    + More
22253936    25835551    24402279    22246508    20360741    21709235    18563158    30282656    20838655    24487278    25329095    23371554    25613341    29023486    15592404    17381049    25069045    24621616    22992520   

EMBL

ODYU01008616    SOQ52353.1    GAIX01000889    JAA91671.1    AAGJ04109445    CR376836    + More
BC139898    HADW01015654    SBP17054.1    HADX01012233    SBP34465.1    JARO02002058    KPP73661.1    NEVH01016967    PNF24795.1    DS235860    EEB19136.1    AERX01017332    GEDC01018736    JAS18562.1    KZ288312    PBC28380.1    NIVC01000497    PAA82064.1    DS469609    EDO39291.1    BT081817    ACO51948.1    KV945941    PIO26095.1    KL438278    KFW93472.1    KQ428349    KOF66257.1    KOF66258.1    NIVC01000844    PAA76071.1    KQ435936    KOX68312.1    KQ414646    KOC66610.1    HE601627    CCD79914.1    KQ041504    KKF26140.1    NIVC01000137    PAA89797.1    JW880627    AFP13144.1    HACA01016368    CDW33729.1    KL251840    KGB41365.1    LSYS01009753    OPJ58761.1    HAEI01012350    SBS14819.1    HAEA01005290    SBQ33770.1    HAEB01003042    HAEC01009121    SBQ49569.1    HAEE01000835    SBR20851.1    HAEJ01007740    SBS48197.1    HAEH01001667    SBR67359.1    HAEF01016843    HAEG01002428    SBR67245.1    HADZ01016302    SBP80243.1    KK696090    KFQ24445.1    KL217608    KFO96936.1    ABQF01039080    AEFK01030854    MUZQ01000304    OWK53100.1    GG666502    EEN61880.1    KK568423    KFW05808.1    ABQF01039078    ABQF01039079    QUSF01000008    RLW07000.1    KL447392    KFO72980.1    AKCR02000106    PKK20593.1    GBXM01013716    JAH94861.1    KK718162    KFO54723.1    QRBI01000119    RMC07826.1    MRZV01000769    PIK44581.1    AADN02036245    PPHD01020148    POI28252.1    KL410781    KFQ99600.1    IACN01015038    IACN01015039    LAB47011.1    AGCU01025754    MCFN01000205    OXB62618.1    KK743354    KFP39427.1    AWGT02000021    OXB82836.1    JH816849    EKC28999.1   

Proteomes

UP000007110    UP000261640    UP000000437    UP000034805    UP000265020    UP000192224    + More
UP000235965    UP000261340    UP000009046    UP000265160    UP000261580    UP000265100    UP000261460    UP000264840    UP000005207    UP000261600    UP000242457    UP000265040    UP000215902    UP000001593    UP000261660    UP000053454    UP000261360    UP000261420    UP000053105    UP000053825    UP000050792    UP000265180    UP000264800    UP000008854    UP000190648    UP000007635    UP000054308    UP000265200    UP000001038    UP000007754    UP000007648    UP000197619    UP000001554    UP000257160    UP000192220    UP000257200    UP000276834    UP000261400    UP000265080    UP000053760    UP000001645    UP000189705    UP000265120    UP000018467    UP000053872    UP000052976    UP000269221    UP000230750    UP000000539    UP000221080    UP000053283    UP000007267    UP000265140    UP000198323    UP000198419    UP000261440    UP000005408    UP000087266   

Pfam

PF09799   Transmemb_17

Interpro

IPR019184   Uncharacterised_TM-17       

ProteinModelPortal

A0A2H1WH09   S4PG27   W4YUN2   A0A3Q3KRW7   A5D6V4   A0A1A7XGV2   + More
A0A1A7YWZ3   A0A0P7UHE5   A0A3Q2CB98   A0A1W4Z510   A0A2J7Q894   A0A3Q0SPR2   E0W0I0   A0A3P9CM18   A0A3Q4HAI6   A0A3P8NM58   A0A3B4H0K9   A0A3Q3BSX2   I3JWC7   A0A1B6CYK2   A0A3Q3JHY9   A0A2A3E9I7   A0A3Q1J2Y8   A0A267G9J1   A7SAJ8   A0A3Q3EBU9   C1C4N8   A0A2G9REA2   A0A093RBM7   A0A0L8FNL4   A0A3B4XD07   A0A3B4VD05   A0A0L8FNP4   A0A267FQM5   A0A0N0BC31   A0A0L7R6W0   A0A183QJ43   A0A3P9KHC8   A0A3Q2ZE67   G4VHQ1   A0A0F8AQ26   A0A267GWU3   V9LIH1   A0A0K2U623   A0A095A273   A0A1V4IFI8   G3PB05   G3PA66   A0A1A8SB05   A0A1A8DHF3   A0A1A8EUN8   A0A1A8JL64   A0A1A8ULK4   A0A1A8NET5   A0A1A8NDT8   A0A1A8CMF5   A0A091QFJ0   A0A091HM53   A0A3P9JTI2   H2MPJ7   H0YVH1   G3WMS7   A0A218UI63   C3YCS9   A0A093IVV9   H0YVH2   A0A3Q1BPJ9   A0A2I4AZZ2   A0A3Q1FZU6   A0A3L8SR47   A0A3B4ZKB1   A0A3P8SQT8   A0A091FR51   G1N0B1   A0A1U7RPW8   A0A3P8WHV9   A0A3B1K9A1   A0A3Q1GQ30   A0A2I0LT41   A0A0E9WXH6   A0A3Q1BTW8   A0A3P8SVP9   A0A091E9J2   A0A3M0K3S0   A0A2G8K990   E1BY51   A0A2P4SVV4   A0A2D0SCL2   A0A091WD82   A0A2D4NMQ0   K7G340   A0A3P8XDB2   A0A226N553   A0A091KH45   A0A226PRX2   A0A3B4CF32   K1QD50   A0A1S3KPQ0  

KEGG

101740715    K19384 transmembrane protein 17 | (RefSeq) transmembrane protein 17-like

GO

GO:0016021   GO:1905515   GO:0035869   GO:0007224   GO:0036038   GO:0060271   GO:0060170  

PANTHER

PTHR13531  

Subcellular location

   Localizes to the transition zone of primary cilia.   With evidence from 1 publications.

Length:

114

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

61.54093

Exp number, first 60 AAs:

37.03097

Total prob of N-in:

0.03072

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  32

inside

33  -  43

TMhelix

44  -  64

outside

65  -  78

TMhelix

79  -  96

inside

97  -  114

 

 

Pi

221.54506

Theta

195.993174

Tajima's D

0.410332

CLR

105.044418

CSRT

0.483225838708065

Interpretation

Uncertain