Gene

KWMTBOMO05788

Pre Gene Modal

BGIBMGA006933

Annotation

PREDICTED:_rRNA_methyltransferase_3?_mitochondrial_[Amyelois_transitella]

Location

Bomo_Chr10(+):10022256-10027883      View in EpiBrowser

Full name

rRNA methyltransferase 3, mitochondrial      

Alternative Name

16S rRNA (guanosine(1370)-2'-O)-methyltransferase
16S rRNA [Gm1370] 2'-O-methyltransferase
RNA methyltransferase-like protein 1

Location in the cell

Cytoplasmic   Reliability : 1.32 Mitochondrial   Reliability : 1.59 Nuclear   Reliability : 1.58

CDS

ATGTGCAACAGATCGTACGCTAGATGGGTTCACAGAAAACCGGCCAAAGTGTTACTTCCTTACGAAAATACAAAAGTAGATTTAAAGAAGGAGAAGATCATTGATTTGGATCCAAGTACAATGAAAAATAATCAAACTGAAGGATTCCCGAAGTCTTCCGTTATAAATTCAGAACTGAAAGAACCCTCGCCTAAATTTTCAAAAGAAAAATGTAAAGAAATAACAGAGCAAAGACAAGATAAAATTAAAAGACGCGAATTCTATTTGAACCAGCAGAAAGTTTTTAATGAAAATAATGAAATAATGTATGAAAAGTTGAAGGGAAATGATGGTCGCGTTAGCACACTTTTAGTAAAATCAAAGTCTAAAAAAGATAGAGCTCGCTCTGGATTGTCATTAGTTGAAGGCTGGAGATTGATTGCTGATGGTCTTCAAGCTGATTGTAAACTTAAATACATCATATTCAGCCGGCTTGATGATTTATATAAGATACGGCCATTCTTACCAACTGTTGGAGTGAAAATTTATAAAATACCATATAAAGATATAGAAATGTGGTCAGATGTTGAAACTTCACCTGGAATTTTTGGTATATTTGAAACACCAACTCCTGGGAATATTAAAAAAAAATCTAATACAATACCATTGAATTTTATCTGTGATAATATTCGTGTTCCTGGTAATTTAGGTGCTATATTGCGTGCTGCTATGGGTGTTGGGTGTGAAAAAGTACTACTGACTAAAGGTTGCGTAGACTTATGGGATCCAAAAGTTATAAGGAGCGCTGCAGGGGCACATTTTCGAGTACCCATCTATCCATCAATAGAATGGAATGAAATGCCTGAACATACAAGACCAGAATCAGCGATTTTCATAGCTGACAGTAATCCAAAGAATACAGTTGAAGATAGCCATGATTCTCTGGCTTCAACTATACCTGTTTTGCCATACTATGGTGTTGATTATTCTACTTTTAGCCATAGCACTTTAATTATAGGAGGTGAAACGGAAGGTATTAGTGAGGATAGTTATAAGTTTGCTTCTAGTCGAAATGGACTGAGACTGAATATTCCCCTTATAGAAGGCGTAGACAGTCTGAACACTGGTATGGCGACAGCTGTAATTGCATGCGAAATAAAAAAACAATTCGTTCAAGCGTGGAGCAAAATGAAAAATGAAAAGGTTGAAGCAGAACTTAACACATAA

Protein

MCNRSYARWVHRKPAKVLLPYENTKVDLKKEKIIDLDPSTMKNNQTEGFPKSSVINSELKEPSPKFSKEKCKEITEQRQDKIKRREFYLNQQKVFNENNEIMYEKLKGNDGRVSTLLVKSKSKKDRARSGLSLVEGWRLIADGLQADCKLKYIIFSRLDDLYKIRPFLPTVGVKIYKIPYKDIEMWSDVETSPGIFGIFETPTPGNIKKKSNTIPLNFICDNIRVPGNLGAILRAAMGVGCEKVLLTKGCVDLWDPKVIRSAAGAHFRVPIYPSIEWNEMPEHTRPESAIFIADSNPKNTVEDSHDSLASTIPVLPYYGVDYSTFSHSTLIIGGETEGISEDSYKFASSRNGLRLNIPLIEGVDSLNTGMATAVIACEIKKQFVQAWSKMKNEKVEAELNT

Description

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Catalytic Activity

guanosine(1370) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(1370) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine

Similarity

Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

Keywords

Complete proteome   Methyltransferase   Mitochondrion   Polymorphism   Reference proteome   rRNA processing   S-adenosyl-L-methionine   Transferase   Transit peptide  

Feature

chain  rRNA methyltransferase 3, mitochondrial
sequence variant  In dbSNP:rs2273454.

Uniprot

H9JBN8   A0A2H1WH01   A0A2W1BU26   A0A2A4K1Y3   A0A194QR51   A0A194Q8C8   + More
A0A212ERF7   D6X2Y6   A0A1W4WHU2   A0A1Y1KQI7   U4U3K9   N6TNN1   A0A0L7R8P4   A0A1B6CM55   F4W7H4   A0A067RQB2   E1ZZY5   A0A2J7RJ38   A0A151X8J6   E9IJ65   A0A026WJV7   A0A195ATY9   A0A195ELY6   A0A151INS2   A0A158NPS2   A0A2J7RJ39   A0A151JTG5   A0A232F193   A0A087ZXK9   K7IT61   A0A0N0BL22   A0A2A3ECC3   A0A154P1J1   E2BZ53   A0A1B6KI39   A0A1B6GBI5   A0A2I4CHT0   A0A1B6J9J2   A0A1B6HTE6   A0A2T7PH74   A0A0K8SP73   A0A0A9Z9Q4   W4YB11   A0A3Q4HYM3   D3ZQG0   A0A3Q0RJQ5   A0A3Q1JNM9   A0A3B4EU87   I3K5Z8   A0A3Q2X858   A0A3Q3B8N0   A0A3B4GL48   A0A224XHB6   A0A1U7Q9X6   G3HTH0   A0A3P9BKB0   A0A3P8NV76   A0A0L0CRG9   A0A2K5LTN3   A0A1A7XHH6   A0A3N0YXM8   I0FT14   A0A2K5VTB9   G1SH27   A0A2G8L9L8   A0A2S2R1Q2   A0A2G9QLM0   A0A3B3BDN5   A0A3P9I033   A0A096P290   G7NHK1   A0A1I8MBH3   A0A091HUW2   A0A3Q2DB02   A0A0S3NUJ1   H9ZAR1   F6SS11   G3RHL5   Q9HC36   A0A3B3I5A0   A0A2J8SNN1   E1BBM0   A0A2K6C2D0   A0A2K5YXB0   H3AEL4   Q5ND52   A0A0D9RP36   L8J387   A0A0S7I225   G2HEA0   A0A3S2MR10   K7CMU7   A0A315VFE0   A0A2I3G0F4  

EC Number

2.1.1.-

Pubmed

19121390    28756777    26354079    22118469    18362917    19820115    + More
28004739    23537049    21719571    24845553    20798317    21282665    24508170    21347285    28648823    20075255    26823975    25401762    25186727    15057822    15632090    21804562    26108605    25319552    21993624    29023486    29451363    17554307    22002653    25315136    26514418    18464734    22398555    14702039    15489334    12296377    21269460    24036117    25074936    24275569    25009282    25944712    19393038    9215903    16141072    19468303    22751099    21484476    16136131    29703783   

EMBL

BABH01024429    ODYU01008616    SOQ52350.1    KZ149900    PZC78568.1    NWSH01000259    + More
PCG77938.1    KQ461175    KPJ07824.1    KQ459302    KPJ01792.1    AGBW02013046    OWR44049.1    KQ971372    EFA10621.1    GEZM01076738    JAV63682.1    KB631879    ERL86898.1    APGK01028401    KB740686    ENN79583.1    KQ414631    KOC67252.1    GEDC01022786    GEDC01007726    JAS14512.1    JAS29572.1    GL887844    EGI69847.1    KK852530    KDR21934.1    GL435531    EFN73257.1    NEVH01003008    PNF40843.1    KQ982409    KYQ56697.1    GL763704    EFZ19388.1    KK107182    EZA55946.1    KQ976745    KYM75449.1    KQ978730    KYN28937.1    KQ976914    KYN07122.1    ADTU01022721    PNF40844.1    KQ982014    KYN30667.1    NNAY01001293    OXU24464.1    AAZX01003295    KQ435689    KOX81264.1    KZ288288    PBC29340.1    KQ434796    KZC05692.1    GL451563    EFN79022.1    GEBQ01029153    JAT10824.1    GECZ01010116    JAS59653.1    GECU01011829    JAS95877.1    GECU01029766    JAS77940.1    PZQS01000004    PVD32775.1    GBRD01011204    GDHC01018453    GDHC01004705    GDHC01000320    JAG54620.1    JAQ00176.1    JAQ13924.1    JAQ18309.1    GBHO01003009    GBHO01003008    GBHO01003007    JAG40595.1    JAG40596.1    JAG40597.1    AAGJ04174674    AABR07072152    CH473948    EDM05258.1    AERX01004941    GFTR01004540    JAW11886.1    JH000697    EGV96742.1    JRES01000005    KNC34960.1    HADW01016117    SBP17517.1    RJVU01019434    ROL50841.1    JV047519    JV636251    AFI37590.1    AFJ71591.1    AQIA01025933    AQIA01025934    AAGW02049788    MRZV01000159    PIK56934.1    GGMS01014758    MBY83961.1    KV951516    PIO16518.1    AHZZ02009454    JU335253    CM001268    AFE79006.1    EHH24321.1    KL217847    KFO99746.1    AB984680    BAT46542.1    JU476223    AFH33027.1    CABD030102904    AK001443    AK222900    AF177344    CH471108    BC011550    BC050614    NDHI03003557    PNJ22376.1    AFYH01129304    AK014739    AK147805    AL591129    BC038288    BC090975    BC115622    BC115623    AQIB01154248    JH880403    ELR61877.1    GBYX01435773    JAO45562.1    AK305064    BAK62058.1    CM012449    RVE65058.1    AACZ04062744    GABC01007257    GABF01008854    GABD01006418    GABE01010991    NBAG03000449    JAA04081.1    JAA13291.1    JAA26682.1    JAA33748.1    PNI23264.1    NHOQ01001816    PWA22116.1    ADFV01123831    ADFV01123832    ADFV01123833   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000007266    + More
UP000192223    UP000030742    UP000019118    UP000053825    UP000007755    UP000027135    UP000000311    UP000235965    UP000075809    UP000053097    UP000078540    UP000078492    UP000078542    UP000005205    UP000078541    UP000215335    UP000005203    UP000002358    UP000053105    UP000242457    UP000076502    UP000008237    UP000192220    UP000245119    UP000007110    UP000261580    UP000002494    UP000261340    UP000265040    UP000261460    UP000005207    UP000264840    UP000264800    UP000189706    UP000001075    UP000265160    UP000265100    UP000037069    UP000233060    UP000233100    UP000001811    UP000230750    UP000261560    UP000265200    UP000028761    UP000095301    UP000054308    UP000265020    UP000002279    UP000001519    UP000005640    UP000001038    UP000009136    UP000233120    UP000233140    UP000008672    UP000000589    UP000029965    UP000002277    UP000001073   

PRIDE

H9JBN8    D3ZQG0    G3HTH0    Q9HC36    Q5ND52   

Pfam

PF00588   SpoU_methylase        + More
PF08032   SpoU_sub_bind

Interpro

IPR029064   L30e-like        + More
IPR029028   Alpha/beta_knot_MTases       
IPR001537   SpoU_MeTrfase       
IPR029026   tRNA_m1G_MTases_N       
IPR013123   SpoU_subst-bd       

SUPFAM

SSF55315   SSF55315        + More
SSF75217   SSF75217       

Gene 3D

3.40.1280.10     3.30.1330.30    

ProteinModelPortal

H9JBN8   A0A2H1WH01   A0A2W1BU26   A0A2A4K1Y3   A0A194QR51   A0A194Q8C8   + More
A0A212ERF7   D6X2Y6   A0A1W4WHU2   A0A1Y1KQI7   U4U3K9   N6TNN1   A0A0L7R8P4   A0A1B6CM55   F4W7H4   A0A067RQB2   E1ZZY5   A0A2J7RJ38   A0A151X8J6   E9IJ65   A0A026WJV7   A0A195ATY9   A0A195ELY6   A0A151INS2   A0A158NPS2   A0A2J7RJ39   A0A151JTG5   A0A232F193   A0A087ZXK9   K7IT61   A0A0N0BL22   A0A2A3ECC3   A0A154P1J1   E2BZ53   A0A1B6KI39   A0A1B6GBI5   A0A2I4CHT0   A0A1B6J9J2   A0A1B6HTE6   A0A2T7PH74   A0A0K8SP73   A0A0A9Z9Q4   W4YB11   A0A3Q4HYM3   D3ZQG0   A0A3Q0RJQ5   A0A3Q1JNM9   A0A3B4EU87   I3K5Z8   A0A3Q2X858   A0A3Q3B8N0   A0A3B4GL48   A0A224XHB6   A0A1U7Q9X6   G3HTH0   A0A3P9BKB0   A0A3P8NV76   A0A0L0CRG9   A0A2K5LTN3   A0A1A7XHH6   A0A3N0YXM8   I0FT14   A0A2K5VTB9   G1SH27   A0A2G8L9L8   A0A2S2R1Q2   A0A2G9QLM0   A0A3B3BDN5   A0A3P9I033   A0A096P290   G7NHK1   A0A1I8MBH3   A0A091HUW2   A0A3Q2DB02   A0A0S3NUJ1   H9ZAR1   F6SS11   G3RHL5   Q9HC36   A0A3B3I5A0   A0A2J8SNN1   E1BBM0   A0A2K6C2D0   A0A2K5YXB0   H3AEL4   Q5ND52   A0A0D9RP36   L8J387   A0A0S7I225   G2HEA0   A0A3S2MR10   K7CMU7   A0A315VFE0   A0A2I3G0F4  

PDB

4X3M     E-value=7.29014e-18,     Score=222

KEGG

778475    K20095 16S rRNA (guanosine(1370)-2'-O)-methyltransferase [EC:2.1.1.-] | (RefSeq) RNA methyltransfera

GO

GO:0008173   GO:0003723   GO:0006396   GO:0005739   GO:0008168   GO:0000451   GO:0070039   GO:0005759   GO:0000160   GO:0005216   GO:0006811   GO:0006541   GO:0016812   GO:0016597  

Subcellular location

Mitochondrion  

Length:

401

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0207

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04806

outside

1  -  401

 

 

Pi

186.587107

Theta

184.186808

Tajima's D

0.843529

CLR

0.012806

CSRT

0.620318984050797

Interpretation

Uncertain