Gene

KWMTBOMO05772  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008205

Annotation

cationic_peptide_CP8_precursor_[Bombyx_mandarina]

Location

Bomo_Chr10(-):9667888-9669937      View in EpiBrowser

Full name

Fungal protease inhibitor-1      

Location in the cell

Extracellular   Reliability : 4.529

CDS

ATGAAAACGTTGATTTTTATAATGCTGGTGGCATGCGTTGCGTCAGCAGCGTACGGTGCTTTGGTATGTGGTACAGACTACTGTGAAAAAAATCCATGCATACAGCCACCACTTGTTTGCCCTAAGAACACTGAGCATCGCGCCAGACACGCTGGAAAGTGTGCTTGTTGTCCCGCTTGTGTAACTTTACTTGGTGAAGGTGCAACTTGCAAGATTTATTCGAAGGAACTAGGCGAAACCCCCTCCGCTGTGTGTAAGGAGCCTCTCAAATGCATCAAAAGAGTTTGCACTAAGCTTGTGTAG

Protein

MKTLIFIMLVACVASAAYGALVCGTDYCEKNPCIQPPLVCPKNTEHRARHAGKCACCPACVTLLGEGATCKIYSKELGETPSAVCKEPLKCIKRVCTKLV

Description

Inhibits proteases from the fungi A.oryzae and R.oryzae, trypsin and chymotrypsin. Does not inhibit protease from the bacterium B.licheniformis or papain.

Similarity

Belongs to the membrane-bound acyltransferase family.

Keywords

3D-structure   Direct protein sequencing   Disulfide bond   Protease inhibitor   Serine protease inhibitor   Signal  

Feature

chain  Fungal protease inhibitor-1

Uniprot

H9JFA8   A1YRL7   Q66PK1   Q6TUD0   S4PJ47   I4DMF2   + More
A0A0N9R053   A0A194RBM1   A0A212EPU4   A0A0K0QRM6   B0JFB8   A0A1E1WEG6   D9MNH4   A0A194Q9Y6   A4LA63   I4DL56   A0A3S2LS50   A0A2H1X195   A0A0K1D8Y0   S5MFH9   A0A2P8XCQ4   N6U8R7   A0A2D0PBQ9   A0A067RGE8   U4U9G4   T1KVP9   A0A1W4WP31   A0A2P8Y9G2   A0A2P8Y9H1  

Pubmed

19121390    23622113    22651552    26354079    22118469    14505696    + More
19263521    20519517    19162182    25977780    23851222    29403074    23537049    24845553   

EMBL

BABH01041601    EF126182    ABL76064.1    AY655143    AAU08172.1    AY387408    + More
AAQ96281.1    GAIX01002767    JAA89793.1    AK402470    BAM19092.1    KR270485    ALH21153.1    KQ460398    KPJ15007.1    AGBW02013372    OWR43513.1    KP713776    AKR15718.1    AM939570    EU375895    CAP74000.1    GDQN01005698    GDQN01001000    JAT85356.1    JAT90054.1    HM448399    ADI87454.1    KQ459302    KPJ01805.1    EF467286    ABO60878.1    AK402024    BAM18646.1    RSAL01000269    RVE43204.1    ODYU01012660    SOQ59089.1    KP792965    AKT09041.1    KC480132    AGR53495.1    PYGN01002990    PSN29770.1    APGK01035488    APGK01035489    APGK01035490    APGK01035491    KB740925    ENN78055.1    HAHE01000092    SNX33522.1    KK852655    KDR19286.1    KB631924    ERL87251.1    CAEY01000613    PYGN01000780    PSN40890.1    PSN40898.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000053268    UP000283053    UP000245037    + More
UP000019118    UP000027135    UP000030742    UP000015104    UP000192223   

PRIDE

H9JFA8    Q66PK1    Q6TUD0   

Pfam

PF12190   amfpi-1        + More
PF03062   MBOAT
PF00002   7tm_2

Interpro

IPR021066   Prot_inhib_I83_AmFPI-1        + More
IPR014371   Oat_ACAT_DAG_ARE       
IPR004299   MBOAT_fam       
IPR017981   GPCR_2-like       
IPR000832   GPCR_2_secretin-like       

ProteinModelPortal

H9JFA8   A1YRL7   Q66PK1   Q6TUD0   S4PJ47   I4DMF2   + More
A0A0N9R053   A0A194RBM1   A0A212EPU4   A0A0K0QRM6   B0JFB8   A0A1E1WEG6   D9MNH4   A0A194Q9Y6   A4LA63   I4DL56   A0A3S2LS50   A0A2H1X195   A0A0K1D8Y0   S5MFH9   A0A2P8XCQ4   N6U8R7   A0A2D0PBQ9   A0A067RGE8   U4U9G4   T1KVP9   A0A1W4WP31   A0A2P8Y9G2   A0A2P8Y9H1  

PDB

3BT4     E-value=1.95563e-15,     Score=194

KEGG

692636    no KO assigned | (RefSeq) CP8; cationic peptide CP8

GO

GO:0008233   GO:0004867   GO:0016021   GO:0008374   GO:0004930   GO:0007166  

PANTHER

PTHR10408  

SignalP

Position:   1 - 19,         Likelihood:  0.999741

 

 

Length:

100

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.23008

Exp number, first 60 AAs:

18.22664

Total prob of N-in:

0.07542

POSSIBLE N-term signal

sequence

outside

1  -  3

TMhelix

4  -  23

inside

24  -  100

 

 

Pi

202.089201

Theta

212.930919

Tajima's D

-0.635442

CLR

0.005638

CSRT

0.212089395530223

Interpretation

Uncertain