Gene

KWMTBOMO05771

Annotation

PREDICTED:_sterol_O-acyltransferase_2_[Bombyx_mori]

Location

Bomo_Chr10(-):9643444-9661477      View in EpiBrowser

Full name

O-acyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 4.819

CDS

ATGTCAACTTCAAATACAGTTCGGCATAGAAAGAGGGCGGAGAATTATGACAGTAATCAAAAAAATATCACTAAGCAGAATGGTGATGTTGATTCAGAGTTTACGACCAGGGAGTCGCCACTGACGGTTCTTATAGACAATTCTCCACATATAAGAGCCCTGTACCATATTTTCGTAGTCATTTTGCTGATGCTGCTGTTCGACACCATGATTTATGACCTTGTGGAAAGAGGAAAAATAAATATTGGGTTAAATGTGATTATCTCCGGTTTTGGCGACATAAAAAGAGGAGCTTTACTCTGGCTGTTTGAATTCGCTGTTGTCCTTGCATTTTACCCGGCTTTAAGAATATACGCGGCGGCGAGGAAACTATTTCGCAAAAATACAGGTGTTCGTGACAGTCTATCTAAACTGGGGGTTATTGGTTTGATCGCCGTGGAAATGGTATTAATCGGGGTACCCATTGTGGACTTGGGAAGGAGACATCTAGCGTTGGCATCTTCGGCAGTTGTAACATGTGAAATGTTCAGATTCTTAATGAAAATTCATGCAGTAGCGATAGCGTGCGCTCCCTATGGTGAAAACGAGAGTCCAGCGCTACCGACCTTCAAGCATTATATTTACTTCTTATTTGCACCCACGCTCGTTTATAGAGATCATTATCCAAGAACAAAGACAATAAGGTGGGCCTTCGTACTATTTCACTTCCTCGAAGTTGCCGCAATAATTTTATACAACAGCTTCCTCTGGGAACGATTCATATTACCTTACTGGTCTGATTATGGAAGACAAAGCAAGGTGGAAGCCGGTTTGGTAGTTCGTGGAATGTTCGCTTGTGTACTTCCAGGATTTATATCATTTCTCTGCGGTTTCTACTGTGTTCTTCATGCGTGGCTAAATGCCTTCGCTGAGATGCTCAAATTTGGAGACAGATTATTTTACGAGGAATGGTGGACTACCTCTCGTTTCTCACACTACTACAGAGCATGGAATCGCGTTGTACATTCTTGGCTGAGAGACCACATTTACAAGCCACTGGCGCCACGTGCCGGTCGAGCCATTTCCACATTCATCGTATTTTTTGTTTCAGCAGTGGCCCACGAAATAATATTGGCCTTATCCTTTGGATTCTTCTACCCTGTTTTGTTAATGGAATTTGGTGTATTCGGACTGTTGATGTTACCACTCACCGCAAGCAGTGGAAGGCGTTTTCCTAATGCATTCAATTTAATAATGTGGCTCTCATTTTTCTTTGGAAACGGACTTCTCTGGAGTCTCTATTCAATGGAATACTTCGCTCGAAAAAATTGTCCACCCTCACAAAGCGACAGTTTTTTCATACCAAAATCATGGTCATGCCCGGAAGTGGTACTTAAACCGGATTGGACATTCCAAAATCCTTTAAGTGTCCTATATTGA

Protein

MSTSNTVRHRKRAENYDSNQKNITKQNGDVDSEFTTRESPLTVLIDNSPHIRALYHIFVVILLMLLFDTMIYDLVERGKINIGLNVIISGFGDIKRGALLWLFEFAVVLAFYPALRIYAAARKLFRKNTGVRDSLSKLGVIGLIAVEMVLIGVPIVDLGRRHLALASSAVVTCEMFRFLMKIHAVAIACAPYGENESPALPTFKHYIYFLFAPTLVYRDHYPRTKTIRWAFVLFHFLEVAAIILYNSFLWERFILPYWSDYGRQSKVEAGLVVRGMFACVLPGFISFLCGFYCVLHAWLNAFAEMLKFGDRLFYEEWWTTSRFSHYYRAWNRVVHSWLRDHIYKPLAPRAGRAISTFIVFFVSAVAHEIILALSFGFFYPVLLMEFGVFGLLMLPLTASSGRRFPNAFNLIMWLSFFFGNGLLWSLYSMEYFARKNCPPSQSDSFFIPKSWSCPEVVLKPDWTFQNPLSVLY

Similarity

Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Belongs to the membrane-bound acyltransferase family.

Uniprot

A0A2W1BW65   S4P9C9   A0A3S2P6V8   A0A194RAX9   A0A212EPX6   A0A194Q9Y6   + More
A0A2A4J8V3   A0A088M9W8   Q16VD9   A0A1S4FMT5   A0A1L8DYB9   A0A182GZS2   A0A1Q3FFX6   B0W793   A0A1L8DY91   W5JGG4   A0A182FW57   A0A182RGI8   A0A182Y200   A0A2M4ASP9   A0A2M4ASL6   A0A2T7PBB2   A0A084WHI5   A0A151IE62   A0A182W9C7   A0A182W9C8   A0A1C7CZL9   Q7Q023   A0A151JT95   Q7PVB3   F4WYN6   A0A2C9JQ08   A0A0L8GFZ3   A0A158NM55   A0A182QNI7   A0A0N0BCH6   A0A195BYR4   A0A151J788   A0A182JE51   A0A2C9JQ14   A0A151J746   A0A182HPV9   K7J0T3   A0A0L7QUM8   A0A0P5PLE1   A0A0P5H8I4   A0A182Y201   A0A164LT80   A0A0P5AW97   A0A0N7ZZL4   A0A0P5MEY3   A0A0P6JPL4   A0A0P6FTQ8   A0A0P5LDB1   A0A151XJJ2   A0A0P5YJ25   A0A182P1Q9   A0A182RGI7   E9FTT9   A0A151WY05   A0A088AEE0   A0A154PRU1   U5EVL3   E9I9X4   A0A1B0CEP5   A0A067RMR2   R7U2P3   A0A151JT65   A0A210R6J1   A0A310SGG1   A0A2J7PJJ2   A0A026WFZ2   F4X0Z0   A0A2J7PJH8   A0A0C9R664   A0A0L0CL69   V4AWR7   A0A3B0K7K6   B4GMZ2   K1QXX4   Q294K6   A0A0R3NRP5   A0A0K8UW11   A0A034WBI5   A7RG44   A0A0A1XL59   A0A151J750   B4K7J6   D0QWL7   A0A1I8QAI7   A0A1A9W6X0   E2C2T4   A0A1D1VRD0   A0A0V0YD85   B3RQI5   A0A2P8XQ87   A0A151IEB2  

Pubmed

28756777    23622113    26354079    22118469    26385554    17510324    + More
26483478    20920257    23761445    25244985    24438588    20966253    12364791    14747013    17210077    21719571    15562597    21347285    20075255    21292972    21282665    24845553    23254933    28812685    24508170    26108605    17994087    22992520    15632085    25348373    17615350    25830018    19859648    20798317    27649274    18719581    29403074   

EMBL

KZ149900    PZC78581.1    GAIX01003804    JAA88756.1    RSAL01000269    RVE43206.1    + More
KQ460398    KPJ15008.1    AGBW02013372    OWR43511.1    KQ459302    KPJ01805.1    NWSH01002617    PCG67842.1    KJ579225    AIN34701.1    CH477596    EAT38531.1    GFDF01002641    JAV11443.1    JXUM01002144    GFDL01008604    JAV26441.1    DS231852    EDS37698.1    GFDF01002722    JAV11362.1    ADMH02001285    ETN63181.1    GGFK01010488    MBW43809.1    GGFK01010453    MBW43774.1    PZQS01000005    PVD30707.1    ATLV01023839    KE525347    KFB49679.1    KQ977890    KYM99003.1    AAAB01008986    EAA00115.4    KQ981960    KYN31901.1    EAA00116.4    GL888455    EGI60671.1    KQ421946    KOF75932.1    ADTU01020290    AXCN02001822    KQ435908    KOX68962.1    KQ976395    KYM93071.1    KQ979737    KYN19378.1    KYN19382.1    APCN01003282    KQ414734    KOC62330.1    GDIQ01128938    JAL22788.1    GDIQ01233596    JAK18129.1    LRGB01003123    KZS04408.1    GDIP01193228    JAJ30174.1    GDIP01197025    JAJ26377.1    GDIQ01180524    JAK71201.1    GDIQ01013049    JAN81688.1    GDIQ01054312    JAN40425.1    GDIQ01181823    JAK69902.1    KQ982060    KYQ60574.1    GDIP01058796    JAM44919.1    GL732524    EFX89584.1    KQ982655    KYQ52764.1    KQ435012    KZC13830.1    GANO01001811    JAB58060.1    GL761847    EFZ22627.1    AJWK01009053    AJWK01009054    AJWK01009055    KK852575    KDR21005.1    AMQN01009626    KB305828    ELU00615.1    KYN31902.1    NEDP02000161    OWF56544.1    KQ770367    OAD52650.1    NEVH01024947    PNF16494.1    KK107238    EZA54858.1    GL888508    EGI59883.1    PNF16496.1    GBYB01008272    JAG78039.1    JRES01000335    KNC32204.1    KB200330    ESP01933.1    OUUW01000008    SPP84050.1    CH479185    EDW38216.1    JH818012    EKC38513.1    CM000070    EAL28962.1    KRT01206.1    GDHF01021558    JAI30756.1    GAKP01007814    JAC51138.1    DS469509    EDO49468.1    GBXI01002672    JAD11620.1    KYN19379.1    CH933806    EDW15340.1    FJ821033    ACN94716.1    GL452203    EFN77769.1    BDGG01000008    GAV02743.1    JYDU01000024    KRX98117.1    DS985243    EDV27251.1    PYGN01001545    PSN34160.1    KYM99004.1   

Proteomes

UP000283053    UP000053240    UP000007151    UP000053268    UP000218220    UP000008820    + More
UP000069940    UP000002320    UP000000673    UP000069272    UP000075900    UP000076408    UP000245119    UP000030765    UP000078542    UP000075920    UP000075882    UP000007062    UP000078541    UP000007755    UP000076420    UP000053454    UP000005205    UP000075886    UP000053105    UP000078540    UP000078492    UP000075880    UP000075840    UP000002358    UP000053825    UP000076858    UP000075809    UP000075885    UP000000305    UP000005203    UP000076502    UP000092461    UP000027135    UP000014760    UP000242188    UP000235965    UP000053097    UP000037069    UP000030746    UP000268350    UP000008744    UP000005408    UP000001819    UP000001593    UP000009192    UP000095300    UP000091820    UP000008237    UP000186922    UP000054815    UP000009022    UP000245037   

Pfam

PF03062   MBOAT        + More
PF12190   amfpi-1
PF00083   Sugar_tr

Interpro

IPR004299   MBOAT_fam        + More
IPR014371   Oat_ACAT_DAG_ARE       
IPR021066   Prot_inhib_I83_AmFPI-1       
IPR005828   MFS_sugar_transport-like       
IPR020846   MFS_dom       
IPR005829   Sugar_transporter_CS       
IPR036259   MFS_trans_sf       
IPR030687   Sterol_acyltranf_meta       

SUPFAM

SSF103473   SSF103473       

CDD

cd06174  MFS

ProteinModelPortal

A0A2W1BW65   S4P9C9   A0A3S2P6V8   A0A194RAX9   A0A212EPX6   A0A194Q9Y6   + More
A0A2A4J8V3   A0A088M9W8   Q16VD9   A0A1S4FMT5   A0A1L8DYB9   A0A182GZS2   A0A1Q3FFX6   B0W793   A0A1L8DY91   W5JGG4   A0A182FW57   A0A182RGI8   A0A182Y200   A0A2M4ASP9   A0A2M4ASL6   A0A2T7PBB2   A0A084WHI5   A0A151IE62   A0A182W9C7   A0A182W9C8   A0A1C7CZL9   Q7Q023   A0A151JT95   Q7PVB3   F4WYN6   A0A2C9JQ08   A0A0L8GFZ3   A0A158NM55   A0A182QNI7   A0A0N0BCH6   A0A195BYR4   A0A151J788   A0A182JE51   A0A2C9JQ14   A0A151J746   A0A182HPV9   K7J0T3   A0A0L7QUM8   A0A0P5PLE1   A0A0P5H8I4   A0A182Y201   A0A164LT80   A0A0P5AW97   A0A0N7ZZL4   A0A0P5MEY3   A0A0P6JPL4   A0A0P6FTQ8   A0A0P5LDB1   A0A151XJJ2   A0A0P5YJ25   A0A182P1Q9   A0A182RGI7   E9FTT9   A0A151WY05   A0A088AEE0   A0A154PRU1   U5EVL3   E9I9X4   A0A1B0CEP5   A0A067RMR2   R7U2P3   A0A151JT65   A0A210R6J1   A0A310SGG1   A0A2J7PJJ2   A0A026WFZ2   F4X0Z0   A0A2J7PJH8   A0A0C9R664   A0A0L0CL69   V4AWR7   A0A3B0K7K6   B4GMZ2   K1QXX4   Q294K6   A0A0R3NRP5   A0A0K8UW11   A0A034WBI5   A7RG44   A0A0A1XL59   A0A151J750   B4K7J6   D0QWL7   A0A1I8QAI7   A0A1A9W6X0   E2C2T4   A0A1D1VRD0   A0A0V0YD85   B3RQI5   A0A2P8XQ87   A0A151IEB2  

KEGG

101740142    K00637 sterol O-acyltransferase [EC:2.3.1.26] | (RefSeq) sterol O-acyltransferase 2

PATHWAY

00100    Steroid biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0005789   GO:0016021   GO:0008374   GO:0016746   GO:0022857   GO:0008203   GO:0034736   GO:0042632   GO:0034435   GO:0006468   GO:0005524   GO:0009190   GO:0016849   GO:0004568   GO:0006032   GO:0006541   GO:0016812   GO:0016597  

PANTHER

PTHR10408  

Subcellular location

Endoplasmic reticulum membrane  

Length:

472

Number of predicted TMHs:

8

Exp number of AAs in TMHs:

177.34855

Exp number, first 60 AAs:

7.81988

Total prob of N-in:

0.98568

inside

1  -  52

TMhelix

53  -  75

outside

76  -  98

TMhelix

99  -  121

inside

122  -  133

TMhelix

134  -  156

outside

157  -  226

TMhelix

227  -  249

inside

250  -  269

TMhelix

270  -  292

outside

293  -  352

TMhelix

353  -  375

inside

376  -  376

TMhelix

377  -  399

outside

400  -  408

TMhelix

409  -  428

inside

429  -  472

 

 

Pi

228.22162

Theta

175.116113

Tajima's D

1.035675

CLR

0.079662

CSRT

0.666316684165792

Interpretation

Uncertain