SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05767  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA006927
Annotation
PREDICTED:_uncharacterized_protein_LOC101745993_[Bombyx_mori]
Location
Bomo_Chr10(-):9619846-9626947      View in EpiBrowser
Full name
Guanylate cyclase      
Transcription factor
bHLH
Location in the cell
Nuclear   Reliability : 3.949
 

Sequence

CDS
ATGGAAAATACTAATAAGCGTACTCCAAGTCGTTGTCGAGAATGGGAAAAACAAAGGCGCAATAAATTTAACGATGCCATATCAAAATTAGGAGAAGCAGTTAAAGCAGTGAATAAAGCCAAGGATCCTAGAAGTACAGAAAATGAAAATGTACAGTATCCAAAAATTGAAATTGTTCAACAAGCAATTTTGTGTCTAACTAATTGTACTCAAGAACGAACACAACTCAAAGCAGAGATATTAGCTTTACAAGTCAAGTTGGAAAGTGCAACTTCGATCAAAGGCGACAGTAAGGACGCTTGCGCCCAAGTGCTTATTCAAGGAGAGAAAAGAGATGTGTCCACTCAGGTCTTCATTGGTGTTAAAAAGAAAGGAAAAAATAGCAAATATGTAAAATTATTAATGTTGCAAAAGTCAAAAAAACATACAAAGAATGAAAAGTTTTTGACCGCCACAACAACTACTGAATCAAGATCTCTACCTAAGCAAATTTTAAAAGAACAGAAGATCTTACCAAAAATAAAGCCTGCATTAAAAGCTCCAGACAACACCATTGTGGTTCTACCCGCAGCACCGTATATTTTTCCTCAGAGGCAATTGCTGTTTCCATCAATAGCACCCGCATTTGTTGTCGTAAACCCAAACATTCCGTCAACGAACAAGCCATCAGTACCGGTGGTTACCAGACACAACAGCGACATTACAAAAACAACAATGGTAAACATTTTACCGATATCCGCGTATTCACGTCCTTTGTCTGCGAAAAATAAAAAAAGTATTGTCAAATTAAAAAATAACAATAATAAACGGAATATTAAAAAAAACAGACCTGTAGAAGTGTCTAAAGCTTCTACTGATAAAGATCAACCTAAAACTAATGAAATGAAAACGCTATCTGACCATAAACCAGACAATGTAGAATTAGAAGCATTAACATCTACTGAGAATATATCTCAGAAAGTAGCGAATAATTGTGAACTCGCAAAACCATTGGGTGATGATATTCAAAGTCATAGTCTAACACTAAATGAAAATACTGAAAAACCTAATTGCCCTAATCTAACAACAAAACAAGCAAGCCCTGCATCTACCCCAACTACAACTTCTCTTAAAGAGACGGTAACACAAGCGAATATTGATTCAATTGTAACAACAGATAAATCAATAGAATCGAAAACGAACACGGAACCCGTTAATGATACTAGTATTGTAAACATCGAAGTTCCCGAAAAATCGACTACAAAAGGAGACAAAGAAAGTAAATTGCCAAATATACTAGAAACTTCGTTGTGCGATGGAACTGTCGACGGCGGTAACGCTAGATTGGAACTGGCCGAAGAATTACTCGCCGCATCACCCACGGCCGCGTTCTTAATGTCTTTCCCGTTAGTAAGCGGTAATAGGGCAGACAGTCCCGCTGAAGATGCTCAAAGTTCCGTACCTATTGCTCCCAAAGAAAACAATCAGAGACGTCGAGAACCAATACAGGAGCCTAGTACGTTTTTCGACAAGCACAACGTAAATCTTAACAAAATCAAGCCAAACAATAAAGCGACCATATGCGAACAAGAAGTAAAGCAAAAACCAAATCCAGCAATCAAAGAGCTCCAACCCCCTAAAACAACTAATATAGCAGTATCGACGGCAAACAACGAAAACCCTTTCTTAAATTTAAGTGTCCCATCCATAGTTTCGACTAATTACACACCAGCCGACCCGACATTTGGAATAGAATTTGATTGTAATATGAATAAAACATTACCAAATCAAACGACGACTTACAGTAACAACTTATTCTATAAGGGGGATCCCTTTAGTTCCGTAAAAAATGCTATTTACAGCACAAGCACAATAACTTCCACGCACGAATTTAATAGCCTCGGTCTTTATCCTTGTGCCATGGAAAAGTACACTTCGAAAAGTAAATCCGACTTCTCGAATGTAGACGAAAACCTCATGAAATTGGGCTCTGCAAGACTAACTTACGATATTGACCTGGGTTGGTCACATAAAGGCCTTGATTTCGTTAACTGCACAACCAATAACGCTACGTTCAGTAAGGACATACTAACAACAGTTTCGGCGCCTTGTTCGACGACGTACAATCCGTTTAATCCAGAATTCCATATCCCATTGGTGTCGAATGCAAAAGAAAACATAACAAACAAGGGAAGTTCCTTTGTAGATACAATTAGCAGCCTTTACTCGCAACCCACGAATTTATGGACAGAAGAATCGCCGTTTTACTCAAACAATGGTGGAACTAAATCCTTAAATTGCAAACCACAGTACTTGCCTACAGATCCATTACAAACCATTCCGAATGCTAAAGTTAATGAACCGAAAATTTACGACACGAAAGTTGGAGAGGCGATTGTTAATAGTAATAGTGTCAAGCCCATTTTAGGAGTAAATTTGCCGGAGAAATATACGAAGAAATCGCCTAGCAAAATGCACATCAATTGGATGACATCTGAAATAAGACCAATGCAAAATTATAATCATACGGCTGAGACGAAGGACATTCAAAGAACGGCTTACAATCAGTTGGATCAAAAACCAACATATAATCACACAAATAATAACACGAAAAAGCATGATTATCACGATGGCAATTATTTTCCCATTACAATGCCTAATTTCCCCGCTCAAACAACTCAAGAAGAATTTCAAATATGGCCTTCAGCAAGACCCCTCGGTACGACTGAAATCAGTATAGATCCTCCGCCCATTAATTTGCCGACATTAGTGGGTGACCTAGCTCTTGGTCCTCATGAAAAAAAGAAGAATATGGAGGCCATAAATAAATTGCAGCCACAGAGTGACATGCAAAACTGTGGGAATTTCTTATCTGTAACTCAACTCATGAACCGCTCTAACGAAAACATGAATACCCGCTATCAGCCACCGATATTTGAGCCGTCAAAAACGGTGAAACAATTTCCGATTCGATCAAACGATCAAAATTTATCACATTTCAGTAGTGAAAATCGTAAAAATGCCGCGGCCAGAATAGAAAACCAATTGCCCCAGCACGGTTACGGTTTTAATGATCACAAAATAGTGAATTCTTACGAGAATAATAACATGGTATCGTATACACAAACAAAACCCAAGGCAAACAAAAATGAAAAAAGCAAATCACAAAAAAACAATTATTCAGCCGAAGCCTTACTCAGGGGTGGGAGCTGTAATCAGAAAATTCAGGACATTAGTAGTGCTAAATACATGCCATCCTCTCAAAAATATAACGAGTTTAATTCGACCGTAGAAACTGGTGTAGCACAAGTGTCTCACTTCCCGCCGATCTTAGATTACACGGAGAATACGTACCAACAACAATTCCCTGGCACTAATCTATACAACGCTACAACGAACACAATCTCGAACTCTTTCTACAGCAACTTCATGCAGAATAGCGGCAACCTCATGACTGGGAATTACGCAAGTGGCCCTTTTCCCGGTGATTTTATTGACTACAACCAACCTACAGAGTGTCACAATTACACAAGTCATAAATACGAAGATCTGAAAATGAGAAACAGTTCGAATTATCAACAAGAAAAACTGCCGTCAAATTACAAGACTTCCAGGAGGGAATCGGCTACGAAACATAAGCTAGAATGTTCTAAAAAAGAGACCAGTAAAAAATTTCAAAGTAAAAGAACCAAACTCAATACTGAAACGGAAGAATGGAATGATTCCTCTCATTTATTGTGGCAGAATAGAAATTCCAACAAAAGACATGCGAATTTAATGCCCGAAGAACTTCCATTTACAAACTATGTGAGTAATCAGATGGCTTCCCAGTATCAATCAGAGTTCCTAAATAGTCATCTTGTTACTTCGAACGTTCAAACCATGGGGCATAATGTGGACAGAACTTTAGCCAGTTTTTCGGGAACATCTCGGGCCAATTTCAATCTCAGCACTATATTCCCTGAAATAACCATGAAGGTCCAGTCGTGA
Protein
MENTNKRTPSRCREWEKQRRNKFNDAISKLGEAVKAVNKAKDPRSTENENVQYPKIEIVQQAILCLTNCTQERTQLKAEILALQVKLESATSIKGDSKDACAQVLIQGEKRDVSTQVFIGVKKKGKNSKYVKLLMLQKSKKHTKNEKFLTATTTTESRSLPKQILKEQKILPKIKPALKAPDNTIVVLPAAPYIFPQRQLLFPSIAPAFVVVNPNIPSTNKPSVPVVTRHNSDITKTTMVNILPISAYSRPLSAKNKKSIVKLKNNNNKRNIKKNRPVEVSKASTDKDQPKTNEMKTLSDHKPDNVELEALTSTENISQKVANNCELAKPLGDDIQSHSLTLNENTEKPNCPNLTTKQASPASTPTTTSLKETVTQANIDSIVTTDKSIESKTNTEPVNDTSIVNIEVPEKSTTKGDKESKLPNILETSLCDGTVDGGNARLELAEELLAASPTAAFLMSFPLVSGNRADSPAEDAQSSVPIAPKENNQRRREPIQEPSTFFDKHNVNLNKIKPNNKATICEQEVKQKPNPAIKELQPPKTTNIAVSTANNENPFLNLSVPSIVSTNYTPADPTFGIEFDCNMNKTLPNQTTTYSNNLFYKGDPFSSVKNAIYSTSTITSTHEFNSLGLYPCAMEKYTSKSKSDFSNVDENLMKLGSARLTYDIDLGWSHKGLDFVNCTTNNATFSKDILTTVSAPCSTTYNPFNPEFHIPLVSNAKENITNKGSSFVDTISSLYSQPTNLWTEESPFYSNNGGTKSLNCKPQYLPTDPLQTIPNAKVNEPKIYDTKVGEAIVNSNSVKPILGVNLPEKYTKKSPSKMHINWMTSEIRPMQNYNHTAETKDIQRTAYNQLDQKPTYNHTNNNTKKHDYHDGNYFPITMPNFPAQTTQEEFQIWPSARPLGTTEISIDPPPINLPTLVGDLALGPHEKKKNMEAINKLQPQSDMQNCGNFLSVTQLMNRSNENMNTRYQPPIFEPSKTVKQFPIRSNDQNLSHFSSENRKNAAARIENQLPQHGYGFNDHKIVNSYENNNMVSYTQTKPKANKNEKSKSQKNNYSAEALLRGGSCNQKIQDISSAKYMPSSQKYNEFNSTVETGVAQVSHFPPILDYTENTYQQQFPGTNLYNATTNTISNSFYSNFMQNSGNLMTGNYASGPFPGDFIDYNQPTECHNYTSHKYEDLKMRNSSNYQQEKLPSNYKTSRRESATKHKLECSKKETSKKFQSKRTKLNTETEEWNDSSHLLWQNRNSNKRHANLMPEELPFTNYVSNQMASQYQSEFLNSHLVTSNVQTMGHNVDRTLASFSGTSRANFNLSTIFPEITMKVQS

Summary

Catalytic Activity
GTP = 3',5'-cyclic GMP + diphosphate
Similarity
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Uniprot
H9JBN2   A0A2H1V4Y4   A0A2W1C349   A0A0L7LLL6   A0A194RCK0   A0A2A4J7I4   + More
A0A212EPV3   A0A194Q8E4  
EC Number
4.6.1.2
Pubmed
19121390    28756777    26227816    26354079    22118469   
EMBL
BABH01024397    BABH01024398    ODYU01000666    SOQ35836.1    KZ149900    PZC78583.1    + More
JTDY01000682    KOB76239.1    KQ460398    KPJ15010.1    NWSH01002617    PCG67839.1    AGBW02013372    OWR43509.1    KQ459302    KPJ01807.1   
Proteomes
UP000005204    UP000037510    UP000053240    UP000218220    UP000007151    UP000053268    + More
PRIDE
H9JBN2   
Pfam
PF00010   HLH        + More
PF01094   ANF_receptor
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc
Interpro
IPR036638   HLH_DNA-bd_sf        + More
IPR011598   bHLH_dom       
IPR029787   Nucleotide_cyclase       
IPR000719   Prot_kinase_dom       
IPR011009   Kinase-like_dom_sf       
IPR018297   A/G_cyclase_CS       
IPR028082   Peripla_BP_I       
IPR001054   A/G_cyclase       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR001828   ANF_lig-bd_rcpt       
SUPFAM
SSF47459   SSF47459        + More
SSF56112   SSF56112       
SSF55073   SSF55073       
SSF53822   SSF53822       
Gene 3D
4.10.280.10     3.30.70.1230    
CDD
cd00083  HLH
ProteinModelPortal
H9JBN2   A0A2H1V4Y4   A0A2W1C349   A0A0L7LLL6   A0A194RCK0   A0A2A4J7I4   + More
A0A212EPV3   A0A194Q8E4  

Ontologies

KEGG
101745993    no KO assigned | (RefSeq) uncharacterized LOC101745993
GO
GO:0046983   GO:0004383   GO:0035556   GO:0004672   GO:0016021   GO:0005524   GO:0006468   GO:0009190   GO:0016849   GO:0004568   GO:0006032   GO:0006541   GO:0016812   GO:0016597  

Topology

Length:
1322
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.01327
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00068
outside
1  -  1322
 
 

Population Genetic Test Statistics

Pi
240.406269
Theta
20.061589
Tajima's D
0.163294
CLR
0.761887
CSRT
0.414879256037198
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
23174119 -.YLPTQDEINEHSDICERR.- 100.00 0.005
23174119 -.IEPPVNKNIPEFFRIMAR.- 100.00 0.005
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