Silkworm Genome Informatics Database

Gene

KWMTBOMO05764

Pre Gene Modal

BGIBMGA006891

Annotation

PREDICTED:_guanylate_cyclase_32E-like_[Bombyx_mori]

Location

Bomo_Chr10(+):9537228-9571509 View in EpiBrowser

Full name

Guanylate cyclase + More
Receptor-type guanylate cyclase Gyc76C

Alternative Name

DrGC-1

Location in the cell

PlasmaMembrane Reliability : 2.136

CDS

ATGTGGCACGGCGCGCGGGTGTTGGTGCTCGCGGCGCTGGGCTTACTGGCCGGGCCTTCGCTTGCCCACAAGAAGTTCAATATCACCATTGGTTACTTACCGGCTCTTACCGGTGACTTGCGAGACAGGCAAGGACTCACAGTCTCAGGGGCACTGTCGATGGCACTTGAAGAGCTGAACAATGGAGTCGACCTGCTGCCGGATGTGGAGATTCAGTTGCAGTGGAATGACACGAAATATGACATGGTGACTTCCACCAGGCTCATCACAGAAATGAGTTGTGCAGGTGTAGCAGCCTTTTTCGGACCCGAAGGTCGCTGTGAAACCGAAGCCATAGTTGCGCAATCCAGAAACCTGCCTATGATCTCTTACAAATGCTCAGACTATCAAGTATCTAGGTTACCAAACTTTGCCCGATTAGAGCCTCCCGGCGTTCAGGCGACAAAATCGTTGATATCGTTGCTACGTTACTATAGATGGAACAAATTCTCTATATTGTATGAAGAATCTTGGATGACGGTCGCCCTGACGTTGGAGAACTATGCCAAGGACTTTAACATGACTGTAAACCATCAGAGGCCCGTCATCAATCATTTTAAATGTTGCGAAGAGAAAATGGCTTGCTGTGCACCCGGTTTCTGGTATCAGTTCATTCATGATACAAAAAACAAAACAAGAATTTACGTTTTCCTTGGGTCGACTTCTGGACTAATAGAGATGATGACCGCCATGGAGTCGCTGCAGCTATTCGCGAAGGGCGAGTACATGGTTATATTCGTGGACATGATGACGTACTCTCTTAAAGACTCTGTCAAGTATTTGTTGAAAACCGAAGATCGTGTATCGTCGACATTAATATGTCCGAATACGCCCGAATTTAAAAAGAGAGCTCAGTCGTTACTGGTGATAGTTTCATCGGAACCATCCCCGGAATATCAAGAGTTTACGGCTAAAGTCAGGAAATACAATTCTCTAGAACCATTCAATTTTCCCGATGTCTTTGGTAGCAAGTACAATAAGTTTGTATCCATTTACGCTGCGTACTTGTATGATTCGGTGAAGCTGTATGCTAAAGCTCTAGATGAAATAATCAAGGAGGAAACTCAAAAGGAGCCCTTGACGCAGGCCAAGCTAACGAATATTGTCACTAACGGAACAGCCATTGTGGCGAAGATGATTAAAAGTTCGCCATACAAAAGTGTGTCCGGTATGACGATACGTTTAGATGATCGTGCCGATTCCGAGGGAAACTTCTCCGTGCTCGCTTTCAAGCCGATAAAATTCAACGAGATTGATATAAACTGCAGTTACAGTATGATACCGGTTGCTCATTTCCAGCAAAACAGTAAAGAGTTTCCTGACTACAAACTAAATTCTCGTATACCGATCGATTGGCCTGACAGCGTGAAACCGGAGGACGAACCGTCTTGCGGTTTCAACAACGAGAAATGTCCAAGGGACGACTCGCAGATAACGTCCCTCGTTGTGGCGGGAACGTTAGCGGTGACTTTGTTTTGTACGTTGGTCGTCACGATCAGCATATACCGAAAATGGAAGATCGAACAAGAAATAGAAGGTTTGCTTTGGAAAATAGACGCACAGGAAGTTACCGGATATTCCGACAACGGCCTCGTGTGCTCGCCCAGTAAGTTGAGCCTAGCGAGCGGTATATCATACGAAATGTGCCCACAAATATTCACCACGACGGCGCAATACAGAGGGAATTTAGTCAGAATAAAAAAATTGAAGTTTTCTAAAAAGAAGGATATATCTCGGGACATAATGAAAGAGATGCGGCTGCTGCGCGAGCTGCGTCACGACAATCTCAACTCGTTCATCGGCGCCGTCGTGGAGCCGATGCGCGTGCTCATCCTCACCGACTACTGTGCCAAGGGGAGCTTGTATGATATAATAGAAAACGAAGATATCAAATTGGATCAAATGTTCATATCTTCGCTTATTCACGATCTCATTAAGGGTATGATCTTCATTCATTCATCGCCTTTAATATTTCACGGAAATCTCAAATCCTCGAATTGTGTAGTTACATCAAGATGGATGTTACAAGTAGCTGATTTTGGTCTCCACGAGTTGAGATATTGGGCTGAAAACGAGTTTATTGGAGAACATCAATATTATAGAGGTTTGCTTTGGAAATCGCCAGAGTTGTTGAGAGGATTAAACAACCCGAATGGCATCGTGGGCGGAACGCAAAAAGGCGACGTCTATGCGTTTGGGATTATTCTATACGAAGTGATAGCGAGAAAAGGCCCTTTTGGAAATGTCGCAATGGAGCCCAAAGATATAATAGACCGCTTGAAGCGGCCGAAGTTGGACGGCGAAGAGTTGTTTCGCCCGGACACGAGCAGCATCGACGGCGGCATCGACGACTACATTGTGTCGTGCATGAAGGACTGCTGGGCAGAAGATCCCAACACGAGACCTGACTTTCCTACGATTAGAACCAGACTAAAGAAGATGAAATCAGGACAATCAAAAAATATAATGGATCAAATGATGGACATCATGGAGAAATACGCTAATAATTTAGAAGAACTAGTCAATGAAAGAACGAGGCTATTGTACGAGGAGAAACAGAAAACCGAAGACTTATTACACAGAATGCTGCCAAAGTCAGTAGCTAGGAGGCTGACGTCCGGGGAGGGGGTTGAACCGGAATCGTTTGACTCGGTGACGATTTACTTCAGCGATATCGTCGGCTTCACGGCCATGTCCGCCGAGAGCACGCCGCTAGAGGTCGTCAACTTTCTCAACGATCTGTATACGGTATTCGACAGGATAATAAGGGGCTACGAAGTGTACAAAGTGGAGACCATAGGTGACGCGTATATGGTGGTATCCGGCCTTCCCATTCGAAATGACGATCGCCACGTTGGTGAGATAGCGTCGATGGCGCTCGAGCTCTTGAACGCCGCTAAAAGTCACAAAATTTCACATCGACCGAAGGAAACTCTCAAACTACGGATTGGAATTCATACGGGAGCTGTGGTGGCGGGCGTGGTCGGCCTCACGATGCCGCGCTACTGCCTGTTCGGGGACACCGTGAACACCGCGTCGCGCATGGAGTCCAACGGGGAACCGCTCCGGATCCACATATCGCCGAGCTGCAAGCAAGCGCTCGACAAGATAGGCGGCTACGTCGTCGAGCCCAGGGGCACGATATCGATCAAAGGAAAAGGACAGCTCCAAACTTATTGGCTCGTGAGCGCTACCGAAAAAGCGATTCAGAAGAGGCCCGTGGAAGAGGAGGAGCGGCCTCTGTTCCGCCGGCCCAGGAGGAGTCCGCGGCTCACGGACTCGCGACACCCATCAGTCACAGGAGTCATAGGCGGGGCGGTCCGACAGAGAGTATCGAGCCTAGCGCGGAACAGCGTGGAGCCCATCGTCGACAGCTTCAACCGCGGCTCGCGCGCGTCCCTGCCCGCACCCGTCTCGTACTCGCCCGTGCGGAGACGGTCGCGCACGGACTACGGTCAGAGGATCAGGAACGCGCTGAGTTCGATCGCGTCGTCGACGGCGTGCGAGCGTGCGCGCTCCTTGGACGTGTTCCCGGGCGAGCACGGCGCGCCCGCCGGACCGGCCGTCTCCACAGTCTCCGGCGAGCGCGTGTTCAACGGGAACGCGCTCCCGGACGAGCCGCCGCCCCCCGAGGAGAGCCCGCTCCTGCGCAAGTGCAGCCTGTACAACCGCCTCGACCTGCCGCGCCGCAAGGTGCACGACTCGAGCTACATCGAGTCGTACAAGCGGTCCCGGTCGCTCGAGAACGTGGGCGACGACAAGTCGGACCGCAAGCCGGCGCGGCTCGCCATCCGCTCGTGGCTGCTCGACATATTCGGCGGCGCCGCCCGCGGCAGCAGCGCCTCCCTGCGCCGCGCCGCCCCGCTCCTCGACCGGGAGTCCGCCGTCTGA

Protein

MWHGARVLVLAALGLLAGPSLAHKKFNITIGYLPALTGDLRDRQGLTVSGALSMALEELNNGVDLLPDVEIQLQWNDTKYDMVTSTRLITEMSCAGVAAFFGPEGRCETEAIVAQSRNLPMISYKCSDYQVSRLPNFARLEPPGVQATKSLISLLRYYRWNKFSILYEESWMTVALTLENYAKDFNMTVNHQRPVINHFKCCEEKMACCAPGFWYQFIHDTKNKTRIYVFLGSTSGLIEMMTAMESLQLFAKGEYMVIFVDMMTYSLKDSVKYLLKTEDRVSSTLICPNTPEFKKRAQSLLVIVSSEPSPEYQEFTAKVRKYNSLEPFNFPDVFGSKYNKFVSIYAAYLYDSVKLYAKALDEIIKEETQKEPLTQAKLTNIVTNGTAIVAKMIKSSPYKSVSGMTIRLDDRADSEGNFSVLAFKPIKFNEIDINCSYSMIPVAHFQQNSKEFPDYKLNSRIPIDWPDSVKPEDEPSCGFNNEKCPRDDSQITSLVVAGTLAVTLFCTLVVTISIYRKWKIEQEIEGLLWKIDAQEVTGYSDNGLVCSPSKLSLASGISYEMCPQIFTTTAQYRGNLVRIKKLKFSKKKDISRDIMKEMRLLRELRHDNLNSFIGAVVEPMRVLILTDYCAKGSLYDIIENEDIKLDQMFISSLIHDLIKGMIFIHSSPLIFHGNLKSSNCVVTSRWMLQVADFGLHELRYWAENEFIGEHQYYRGLLWKSPELLRGLNNPNGIVGGTQKGDVYAFGIILYEVIARKGPFGNVAMEPKDIIDRLKRPKLDGEELFRPDTSSIDGGIDDYIVSCMKDCWAEDPNTRPDFPTIRTRLKKMKSGQSKNIMDQMMDIMEKYANNLEELVNERTRLLYEEKQKTEDLLHRMLPKSVARRLTSGEGVEPESFDSVTIYFSDIVGFTAMSAESTPLEVVNFLNDLYTVFDRIIRGYEVYKVETIGDAYMVVSGLPIRNDDRHVGEIASMALELLNAAKSHKISHRPKETLKLRIGIHTGAVVAGVVGLTMPRYCLFGDTVNTASRMESNGEPLRIHISPSCKQALDKIGGYVVEPRGTISIKGKGQLQTYWLVSATEKAIQKRPVEEEERPLFRRPRRSPRLTDSRHPSVTGVIGGAVRQRVSSLARNSVEPIVDSFNRGSRASLPAPVSYSPVRRRSRTDYGQRIRNALSSIASSTACERARSLDVFPGEHGAPAGPAVSTVSGERVFNGNALPDEPPPPEESPLLRKCSLYNRLDLPRRKVHDSSYIESYKRSRSLENVGDDKSDRKPARLAIRSWLLDIFGGAARGSSASLRRAAPLLDRESAV

Description

Guanylate cyclase involved in the production of the second messenger cGMP (PubMed:24284209). Acts as a receptor for the NPLP1-4 peptide and modulates the innate immune IMD pathway in response to salt stress by inducing nuclear translocation of NF-kappa-B protein Rel which leads to increased expression of the antimicrobial peptide diptericin (PubMed:21893139). Plays a role in Sema-1a-mediated axon repulsion which is required for the correct establishment of neuromuscular connectivity (PubMed:15282266, PubMed:24284209). Required in developing embryonic somatic muscle for correct patterning of ventral and lateral muscles and for localization of integrin beta-ps at developing dorsal muscle myotendinous junctions (PubMed:23213443). Required for invagination, migration and lumen shape of the embryonic salivary gland by regulating the localization of the integrin-binding protein rhea/Talin to the visceral mesoderm surrounding the gland and maintaining the laminin matrix (PubMed:23862019). Required in the developing wing to regulate extracellular matrix (ECM) organization by activating the cGMP-dependent protein kinase For which represses the activity of matrix metalloproteases such as Mmp2 and decreases ECM matrix reorganization (PubMed:26440503).

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Subunit

Interacts with the semaphorin 1A receptor PlexA; PlexA enhances Gyc76C catalytic activity. Interacts with the PDZ domain-containing protein kermit; kermit increases cell surface expression of Gyc76C.

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

ATP-binding Cell membrane cGMP biosynthesis Complete proteome Glycoprotein GTP-binding Lyase Magnesium Membrane Metal-binding Nucleotide-binding Receptor Reference proteome Signal Transmembrane Transmembrane helix

Feature

chain Guanylate cyclase

Uniprot

H9JBJ6 A0A3S2LS11 A0A2H1WKG2 A0A2W1BY57 A0A194Q8F6 A0A2A4J2G4 + More
A0A212F645 A0A1L8DJG1 A0A1L8DJR8 A0A1L8DJP0 A0A1L8DJP4 A0A1L8DJE6 A0A1L8DJF6 T1PCH4 D6X177 A0A0L0C8M8 A0A1W4XT11 Q16YZ6 A0A1Y1M579 W8AIX8 A0A182HEV4 A0A1I8PNZ6 A0A034V957 A0A182PGB7 A0A182WD90 Q7PZZ3 A0A1A9ZDW0 A0A182HPR9 A0A1A9UKP9 A0A182X009 A0A1B0C6N8 E0VCX6 A0A1A9XJW6 A0A084WB37 A0A1B0GF71 A0A1A9W5X4 A0A1J1IPW9 A0A0A1X4C8 A0A182J455 A0A0A1WZK5 A0A182QXR8 A0A182KT21 A0A2M4A4N6 A0A182FW72 A0A2M4A487 A0A2M4A468 A0A2M3YZT9 A0A1B0CUZ5 A0A0M4EG81 B4N3M7 K7J3D3 B4LGE0 B4KY29 A0A2M4CIM0 A0A2M4CKB0 A0A2M4CLW1 B5DRL7 A0A3B0J659 B3M6J3 A0A0L7RJ80 A4V243 Q7JQ32 B4QQX8 B3NII0 B4PFY8 A0A1W4UDX7 A0A336LXX4 A0A182MXC5 A0A067QVM8 A0A151X5N2 A0A158NJ88 A0A151JZJ7 U4TZM5 N6UEX4 A0A182RXD1 A0A3L8DCZ8 B4IIP9 A0A1B6MKA2 A0A1B6F1B7 A0A2H8TK31 J9JNT2 A0A1B6EEF4 A0A088AVQ7 A0A2P8YZ06 A0A2S2R4A9 B4IWW8 A0A224XIA1 A0A182YQ82 A0A023F3B8 B0WSE8 A0A0M8ZPG3 E9J8Y6 A0A195BKT2 A0A151IK46 A0A2A3ERN6 A0A2J7Q239

EC Number

4.6.1.2

Pubmed

19121390 28756777 26354079 22118469 25315136 18362917 + More
19820115 26108605 17510324 28004739 24495485 26483478 25348373 12364791 20566863 24438588 25830018 20966253 17994087 20075255 15632085 23185243 10731132 12537568 12537572 12537573 12537574 16110336 17569856 17569867 26109357 26109356 7706258 7759483 15282266 23213443 21893139 23862019 24284209 26440503 22936249 17550304 24845553 21347285 23537049 30249741 29403074 25244985 25474469 21282665

EMBL

BABH01030970 BABH01030971 BABH01030972 RSAL01000275 RVE43120.1 ODYU01009272 + More
SOQ53570.1 KZ149900 PZC78585.1 KQ459302 KPJ01808.1 NWSH01003611 PCG66059.1 AGBW02010077 OWR49210.1 GFDF01007498 JAV06586.1 GFDF01007500 JAV06584.1 GFDF01007499 JAV06585.1 GFDF01007497 JAV06587.1 GFDF01007496 JAV06588.1 GFDF01007501 JAV06583.1 KA645835 AFP60464.1 KQ971372 EFA10586.2 JRES01000760 KNC28587.1 CH477506 EAT39830.1 GEZM01043506 JAV79046.1 GAMC01020881 GAMC01020880 GAMC01020878 JAB85677.1 JXUM01036120 JXUM01036121 JXUM01036122 JXUM01036123 JXUM01036124 JXUM01036125 JXUM01036126 JXUM01036127 KQ561084 KXJ79765.1 GAKP01019888 GAKP01019887 JAC39064.1 AAAB01008986 EAA00176.4 APCN01003270 JXJN01026843 DS235068 EEB11232.1 ATLV01022307 ATLV01022308 KE525331 KFB47431.1 CCAG010012768 CVRI01000055 CRL01142.1 GBXI01015827 GBXI01008764 GBXI01005765 JAC98464.1 JAD05528.1 JAD08527.1 GBXI01010499 JAD03793.1 AXCN02001683 GGFK01002453 MBW35774.1 GGFK01002303 MBW35624.1 GGFK01002283 MBW35604.1 GGFM01001015 MBW21766.1 AJWK01029883 AJWK01029884 AJWK01029885 AJWK01029886 AJWK01029887 AJWK01029888 AJWK01029889 CP012525 ALC45096.1 CH964095 EDW79232.1 CH940647 EDW70469.1 CH933809 EDW18731.1 GGFL01001032 MBW65210.1 GGFL01001598 MBW65776.1 GGFL01001700 MBW65878.1 CH379070 EDY74228.1 OUUW01000002 SPP77407.1 CH902618 EDV40842.1 KQ414582 KOC70843.1 AE014296 AAF49117.1 AAV50029.1 L35598 U23485 BT011062 AAA74408.1 AAA85858.1 AAR31133.1 CM000363 CM002912 EDX11116.1 KMZ00596.1 CH954178 EDV52405.1 CM000159 EDW95285.1 UFQT01000216 SSX21841.1 KK853196 KDR09972.1 KQ982498 KYQ55696.1 ADTU01017581 ADTU01017582 ADTU01017583 ADTU01017584 ADTU01017585 ADTU01017586 ADTU01017587 KQ981427 KYN41775.1 KB631805 ERL86282.1 APGK01029504 APGK01029505 APGK01029506 KB740735 ENN79171.1 QOIP01000010 RLU18186.1 CH480844 EDW49820.1 GEBQ01016200 GEBQ01014835 GEBQ01003621 JAT23777.1 JAT25142.1 JAT36356.1 GECZ01025815 GECZ01004426 JAS43954.1 JAS65343.1 GFXV01002712 MBW14517.1 ABLF02031542 ABLF02031545 ABLF02043285 GEDC01007580 GEDC01000969 JAS29718.1 JAS36329.1 PYGN01000278 PSN49479.1 GGMS01015560 MBY84763.1 CH916366 EDV97369.1 GFTR01008655 JAW07771.1 GBBI01002797 JAC15915.1 DS232069 EDS33793.1 KQ435922 KOX68415.1 GL769162 EFZ10727.1 KQ976453 KYM85379.1 KQ977255 KYN04643.1 KZ288198 PBC33701.1 NEVH01019373 PNF22646.1

Proteomes

UP000005204 UP000283053 UP000053268 UP000218220 UP000007151 UP000095301 + More
UP000007266 UP000037069 UP000192223 UP000008820 UP000069940 UP000249989 UP000095300 UP000075885 UP000075920 UP000007062 UP000092445 UP000075840 UP000078200 UP000076407 UP000092460 UP000009046 UP000092443 UP000030765 UP000092444 UP000091820 UP000183832 UP000075880 UP000075886 UP000075882 UP000069272 UP000092461 UP000092553 UP000007798 UP000002358 UP000008792 UP000009192 UP000001819 UP000268350 UP000007801 UP000053825 UP000000803 UP000000304 UP000008711 UP000002282 UP000192221 UP000075884 UP000027135 UP000075809 UP000005205 UP000078541 UP000030742 UP000019118 UP000075900 UP000279307 UP000001292 UP000007819 UP000005203 UP000245037 UP000001070 UP000076408 UP000002320 UP000053105 UP000078540 UP000078542 UP000242457 UP000235965

PRIDE

H9JBJ6 Q7JQ32

Pfam

PF01094   ANF_receptor        + More
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF07701   HNOBA

Interpro

IPR000719   Prot_kinase_dom        + More
IPR029787   Nucleotide_cyclase
IPR028082   Peripla_BP_I
IPR001054   A/G_cyclase
IPR011009   Kinase-like_dom_sf
IPR001828   ANF_lig-bd_rcpt
IPR001245   Ser-Thr/Tyr_kinase_cat_dom
IPR018297   A/G_cyclase_CS
IPR011645   HNOB_dom_associated

SUPFAM

SSF56112   SSF56112        + More
SSF53822   SSF53822
SSF55073   SSF55073

Gene 3D

3.30.70.1230

ProteinModelPortal

H9JBJ6 A0A3S2LS11 A0A2H1WKG2 A0A2W1BY57 A0A194Q8F6 A0A2A4J2G4 + More
A0A212F645 A0A1L8DJG1 A0A1L8DJR8 A0A1L8DJP0 A0A1L8DJP4 A0A1L8DJE6 A0A1L8DJF6 T1PCH4 D6X177 A0A0L0C8M8 A0A1W4XT11 Q16YZ6 A0A1Y1M579 W8AIX8 A0A182HEV4 A0A1I8PNZ6 A0A034V957 A0A182PGB7 A0A182WD90 Q7PZZ3 A0A1A9ZDW0 A0A182HPR9 A0A1A9UKP9 A0A182X009 A0A1B0C6N8 E0VCX6 A0A1A9XJW6 A0A084WB37 A0A1B0GF71 A0A1A9W5X4 A0A1J1IPW9 A0A0A1X4C8 A0A182J455 A0A0A1WZK5 A0A182QXR8 A0A182KT21 A0A2M4A4N6 A0A182FW72 A0A2M4A487 A0A2M4A468 A0A2M3YZT9 A0A1B0CUZ5 A0A0M4EG81 B4N3M7 K7J3D3 B4LGE0 B4KY29 A0A2M4CIM0 A0A2M4CKB0 A0A2M4CLW1 B5DRL7 A0A3B0J659 B3M6J3 A0A0L7RJ80 A4V243 Q7JQ32 B4QQX8 B3NII0 B4PFY8 A0A1W4UDX7 A0A336LXX4 A0A182MXC5 A0A067QVM8 A0A151X5N2 A0A158NJ88 A0A151JZJ7 U4TZM5 N6UEX4 A0A182RXD1 A0A3L8DCZ8 B4IIP9 A0A1B6MKA2 A0A1B6F1B7 A0A2H8TK31 J9JNT2 A0A1B6EEF4 A0A088AVQ7 A0A2P8YZ06 A0A2S2R4A9 B4IWW8 A0A224XIA1 A0A182YQ82 A0A023F3B8 B0WSE8 A0A0M8ZPG3 E9J8Y6 A0A195BKT2 A0A151IK46 A0A2A3ERN6 A0A2J7Q239

PDB

3ET6 E-value=7.74578e-36, Score=382

KEGG

101736434 K01769 guanylate cyclase, other [EC:4.6.1.2] | (RefSeq) guanylate cyclase 32E-like

PATHWAY

00230 Purine metabolism - Bombyx mori (domestic silkworm)
01100 Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005524 GO:0004383 GO:0004672 GO:0035556 GO:0016021 GO:0000166 GO:0006182 GO:0007165 GO:0007168 GO:0001653 GO:0005886 GO:0019934 GO:0038023 GO:0005887 GO:0030215 GO:0030510 GO:0009651 GO:0005525 GO:0007411 GO:0007428 GO:0008045 GO:0016199 GO:0046872 GO:0007526 GO:0030198 GO:0007435 GO:0006468 GO:0009190 GO:0016849 GO:0004568 GO:0006032 GO:0006541 GO:0016812 GO:0016597

Subcellular location

Cell membrane

SignalP

Position: 1 - 22, Likelihood: 0.988161

Length:

1309

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

19.6885

Exp number, first 60 AAs:

7.57216999999999

Total prob of N-in:

0.26897

outside

1 - 1309

Pi

176.28819

Theta

169.945299

Tajima's D

0.179408

CLR

0.183679

CSRT

0.423828808559572

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics

Multiple alignment of Orthologues

Gene Tree