Gene

KWMTBOMO05672  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006840

Annotation

eukaryotic_translation_initiation_factor_1A_[Bombyx_mori]

Location

Bomo_Chr10(+):7812168-7814925      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.841 Nuclear   Reliability : 2.418

CDS

ATGCCGAAAAACAAAGGTAAAGGAGGAAAAAATAGGAGGCGAGGAAAGAACGAAAATGAAACTGAAAAACGTGAGTTGGTCTTTAAGGAAGACGGACAAGAGTACGCCCAAGTCACAAAGATGCTCGGTAATGGCCGCTTGGAGGCCATGTGCTTTGATGGCATCAAACGCCTGTGTCACATCCGAGGGAAACTACGAAAAAAAGTGTGGATAAATCAAGGAGACATAATATTAATAGGCCTACGAGATTATCAAGATGCGAAAGCTGATGTCATCTTGAAATATACCCCTGACGAAGCTAGGAATCTAAAGACGTATGGAGAATTCCCAGAAACGGTCCGCATCAATGAGACAGTAGTGTATTCTGTGGATGGATTAGATGAAGATATTGAATTTGGAGATGAAGTCAGTTCAGAGGATGAAGCTGATGATGTGTGA

Protein

MPKNKGKGGKNRRRGKNENETEKRELVFKEDGQEYAQVTKMLGNGRLEAMCFDGIKRLCHIRGKLRKKVWINQGDIILIGLRDYQDAKADVILKYTPDEARNLKTYGEFPETVRINETVVYSVDGLDEDIEFGDEVSSEDEADDV

Description

Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

Similarity

Belongs to the eIF-1A family.

Uniprot

A0A2A4IZ12   A0A3S2NL72   A0A2H1WP48   A0A194PK87   S4NT11   A0A212EII4   + More
A0A1E1W080   A0A0L7LWN1   Q2F5R9   A0A0T6AU14   A0A1B6L713   A0A1B6FVV5   A0A1B6I4U4   A0A067R6J5   R4UKL0   A0A1Y1MR91   A0A2J7QW47   E2C1X0   D6WFK0   A0A0J7L1C2   A0A0N0U5G3   E2A637   E9JCX7   A0A2S2QK89   E0VEI0   V9IFG1   A0A088A5I9   A0A158NYG8   A0A3L8DVM7   A0A232F9H2   A0A1S3D896   K7IZZ2   A0A151WHM9   A0A2A3EF82   A0A1B6CZC5   A0A336LNH2   A0A0L7QTL6   A0A151J9U6   A0A1W4UK01   B4QUG7   A0A3B0JNP8   B4GF16   B3MTQ0   B4NG83   B4IB73   B4JZ17   B3NZ80   B4KD71   Q296K1   Q9VEA1   B4LZ28   Q6XIF3   A0A310SQQ4   C4WS17   A0A2S2NE07   C4WS03   T1IBY2   A0A154P695   A0A0P4VRV8   R4G4D8   D3TS50   A0A1A9Y3Z5   A0A1B0BSP0   U5EWE3   A0A0K8TR31   Q9NJB4   A0A1B6GQ93   A0A2R7WR78   R4WCZ7   A0A0A9ZE08   A0A195AZ79   V5H0X6   A0A0L0BWB1   A0A0A1WXE3   A0A0K8VWA5   W8C789   A0A0C9QJU9   A0A034V8N6   A0A1L8DRQ7   A0A1B0GNV3   A0A1B0CC64   F4WT32   A0A182MQ59   A0A182PFG5   A0A182QZT3   A0A182UXX0   A0A182N6Q3   A0A182KA70   A0A182U6B5   A0A182W2V3   A0A084W4Y4   A0A182LC62   A0A182JD26   A0A182XEB2   Q9U9L3   A0A182RYE5   A0A182HJ10   A0A182XVL9   T1DQ18   A0A2M3Z042  

Pubmed

26354079    23622113    22118469    26227816    19121390    24845553    + More
28004739    20798317    18362917    19820115    21282665    20566863    21347285    30249741    28648823    20075255    17994087    18057021    15632085    23185243    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    14525923    17550304    27129103    20353571    26369729    10689194    23691247    25401762    26823975    26108605    25830018    24495485    25348373    21719571    24438588    20966253    12364791    14747013    17210077    25244985   

EMBL

NWSH01005003    PCG64504.1    RSAL01000312    RVE42663.1    ODYU01009959    SOQ54722.1    + More
KQ459606    KPI91510.1    GAIX01013832    JAA78728.1    AGBW02014631    OWR41299.1    GDQN01010667    JAT80387.1    JTDY01000002    KOB79530.1    KOB79531.1    BABH01030817    DQ311354    ABD36298.1    LJIG01022802    KRT78639.1    GEBQ01020459    JAT19518.1    GECZ01015490    JAS54279.1    GECU01025750    JAS81956.1    KK852667    KDR18925.1    KC740840    AGM32664.1    GEZM01025098    JAV87588.1    NEVH01009768    PNF32807.1    GL452008    EFN78082.1    KQ971328    EFA00932.1    LBMM01001460    KMQ96279.1    KQ435775    KOX75028.1    GL437108    EFN71096.1    GL771866    EFZ09339.1    GGMS01008954    MBY78157.1    DS235091    EEB11786.1    JR043827    AEY59810.1    ADTU01003818    QOIP01000003    RLU24386.1    NNAY01000597    OXU27486.1    KQ983114    KYQ47305.1    KZ288262    PBC30380.1    GEDC01018488    JAS18810.1    UFQT01000027    SSX18149.1    KQ414747    KOC61884.1    KQ979403    KYN21723.1    CM000364    EDX12467.1    OUUW01000008    SPP83864.1    CH479182    EDW34201.1    CH902623    EDV30181.1    CH964251    EDW83300.1    CH480827    EDW44631.1    CH916378    EDV98632.1    CH954181    EDV48622.1    CH933806    EDW14853.1    KRG01246.1    CM000070    EAL28456.1    KRT00737.1    KRT00738.1    AE014297    AY113498    KX531962    AAF55526.1    AAM29503.1    AAS65169.1    AHN57385.1    ANY27772.1    CH940650    EDW68131.1    KRF83691.1    AY231877    CM000160    AAR09900.1    EDW95880.1    KRK02782.1    KQ761592    OAD57375.1    ABLF02027277    AK340010    BAH70687.1    GGMR01002397    MBY15016.1    ABLF02031182    AK339993    BAH70673.1    ACPB03004429    KQ434817    KZC06874.1    GDKW01001284    JAI55311.1    GAHY01000856    JAA76654.1    EZ424252    ADD20528.1    JXJN01019786    GANO01001457    JAB58414.1    GDAI01001223    JAI16380.1    AF169359    AAF44294.1    GECZ01005165    JAS64604.1    KK855240    PTY21610.1    AK417069    BAN20284.1    GBHO01000950    GBHO01000947    GDHC01000874    JAG42654.1    JAG42657.1    JAQ17755.1    KQ976701    KYM77264.1    GALX01001983    JAB66483.1    JRES01001243    KNC24320.1    GBXI01010568    JAD03724.1    GDHF01019221    GDHF01012353    GDHF01009499    JAI33093.1    JAI39961.1    JAI42815.1    GAMC01003769    GAMC01003768    JAC02787.1    GBYB01003773    GBYB01003774    JAG73540.1    JAG73541.1    GAKP01019305    GAKP01019301    JAC39651.1    GFDF01004941    JAV09143.1    AJVK01029820    AJVK01029821    AJWK01006207    GL888331    EGI62645.1    AXCM01000405    AXCN02000061    ATLV01020424    KE525302    KFB45278.1    AXCP01002812    AF164151    AAAB01008879    AAD47075.1    EAA08471.2    APCN01002114    GAMD01002839    JAA98751.1    GGFM01001132    MBW21883.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000007151    UP000037510    UP000005204    + More
UP000027135    UP000235965    UP000008237    UP000007266    UP000036403    UP000053105    UP000000311    UP000009046    UP000005203    UP000005205    UP000279307    UP000215335    UP000079169    UP000002358    UP000075809    UP000242457    UP000053825    UP000078492    UP000192221    UP000000304    UP000268350    UP000008744    UP000007801    UP000007798    UP000001292    UP000001070    UP000008711    UP000009192    UP000001819    UP000000803    UP000008792    UP000002282    UP000007819    UP000015103    UP000076502    UP000092443    UP000092460    UP000078540    UP000037069    UP000092462    UP000092461    UP000007755    UP000075883    UP000075885    UP000075886    UP000075903    UP000075884    UP000075881    UP000075902    UP000075920    UP000030765    UP000075882    UP000075880    UP000076407    UP000007062    UP000075900    UP000075840    UP000076408   

PRIDE

Q2F5R9    Q9VEA1    Q9NJB4   

Pfam

PF01176   eIF-1a        + More
PF15433   MRP-S31

Interpro

IPR006196   RNA-binding_domain_S1_IF1        + More
IPR001253   TIF_eIF-1A       
IPR018104   TIF_eIF-1A_CS       
IPR012340   NA-bd_OB-fold       
IPR026299   MRP-S31       

SUPFAM

SSF50249   SSF50249       

CDD

cd05793  S1_IF1A

ProteinModelPortal

A0A2A4IZ12   A0A3S2NL72   A0A2H1WP48   A0A194PK87   S4NT11   A0A212EII4   + More
A0A1E1W080   A0A0L7LWN1   Q2F5R9   A0A0T6AU14   A0A1B6L713   A0A1B6FVV5   A0A1B6I4U4   A0A067R6J5   R4UKL0   A0A1Y1MR91   A0A2J7QW47   E2C1X0   D6WFK0   A0A0J7L1C2   A0A0N0U5G3   E2A637   E9JCX7   A0A2S2QK89   E0VEI0   V9IFG1   A0A088A5I9   A0A158NYG8   A0A3L8DVM7   A0A232F9H2   A0A1S3D896   K7IZZ2   A0A151WHM9   A0A2A3EF82   A0A1B6CZC5   A0A336LNH2   A0A0L7QTL6   A0A151J9U6   A0A1W4UK01   B4QUG7   A0A3B0JNP8   B4GF16   B3MTQ0   B4NG83   B4IB73   B4JZ17   B3NZ80   B4KD71   Q296K1   Q9VEA1   B4LZ28   Q6XIF3   A0A310SQQ4   C4WS17   A0A2S2NE07   C4WS03   T1IBY2   A0A154P695   A0A0P4VRV8   R4G4D8   D3TS50   A0A1A9Y3Z5   A0A1B0BSP0   U5EWE3   A0A0K8TR31   Q9NJB4   A0A1B6GQ93   A0A2R7WR78   R4WCZ7   A0A0A9ZE08   A0A195AZ79   V5H0X6   A0A0L0BWB1   A0A0A1WXE3   A0A0K8VWA5   W8C789   A0A0C9QJU9   A0A034V8N6   A0A1L8DRQ7   A0A1B0GNV3   A0A1B0CC64   F4WT32   A0A182MQ59   A0A182PFG5   A0A182QZT3   A0A182UXX0   A0A182N6Q3   A0A182KA70   A0A182U6B5   A0A182W2V3   A0A084W4Y4   A0A182LC62   A0A182JD26   A0A182XEB2   Q9U9L3   A0A182RYE5   A0A182HJ10   A0A182XVL9   T1DQ18   A0A2M3Z042  

PDB

4KZZ     E-value=4.14978e-41,     Score=416

KEGG

100101157    K03236 translation initiation factor 1A | (RefSeq) eukaryotic translation initiation factor 1A

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0003743   GO:0006413   GO:0016282   GO:0005654   GO:0006412   GO:0005829   GO:0003735   GO:0016021   GO:0005763   GO:0003723   GO:0008270   GO:0043565   GO:0003677   GO:0004887   GO:0043401   GO:0003707  

PANTHER

PTHR21668  

Length:

145

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0007

Exp number, first 60 AAs:

0

Total prob of N-in:

0.28490

outside

1  -  145

 

 

Pi

211.881115

Theta

205.040546

Tajima's D

0.040625

CLR

145.521539

CSRT

0.377831108444578

Interpretation

Uncertain