Gene

KWMTBOMO05670  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014046

Annotation

putative_ribosomal_RNA_methyltransferase_[Danaus_plexippus]

Location

Bomo_Chr10(+):7577233-7584263      View in EpiBrowser

Full name

Putative rRNA methyltransferase      

Alternative Name

2'-O-ribose RNA methyltransferase SPB1 homolog

Location in the cell

Nuclear   Reliability : 4.001

CDS

ATGGGAAAGAAAACAAAAGTAGGAAAACAACGGAAAGATAAATACTACCAACTAGCTAAAGAAACAGGATATAGATCAAGAGCTGCATTCAAATTAATACAATTGAACAGGAAATTTGGATTTTTGCAGAAATCACGAGTATGTATCGATTTATGTGCTGCACCTGGTGGGTGGATGCAGGTGGCCCACCAAAATATGCCAGTCTCGAGCATAGTAATAGGAGTCGATTTGTTTCCAATAAAACCAGTTCCAGGTTGTATAGGTCTGACTGAAGATATCACTACAGAAAAATGTAAGGCAGCAATCAAAAAAGAAATAAAAACATGGAAAGCTGATGTGGTACTTAATGACGGTGCACCCAATGTCGGTCTTAATTGGATCCATGATGCCTATCAACAAGCTTGTCTAACGTTGAGTGCTTTAAAACTTGCAACGAACTTCCTCAGAGAAGGTGGTTGGTTTGTGACTAAAGTATTCAGATCGAAAGACTATCATGCACTTTTATGGGTTCTGAAACAATTCTTCAAAAAAGTACATGCTACAAAGCCCCAAGCTTCTCGTAATGAGTCTTCTGAAATTTTCGTTGTATGTCAGGGCTATATTGCACCAGATACAATTGATCCTAAATTTCTCGACCCCAAACATGTCTTTGAAGATCTTGATATAGTTAAAAAACAGCATATAAATATATTACATCCTGAGAAACAAAAAAAAGCAAAAGCAGAAGGATATAAAGAAAATGATTATACCACACATCATAAAGTAAAACTGTCTGATTTTTTGGGAAAAGATGATCCAGTAGATCTACTTCATGGTTGCTCTGAGATTGTTTTCGATGATAAGGAAATAGAAACTCATCCAAAGACAACACCAGAAATAAAGGAATGTTGTAAGGATATTAAGGTGCTTGGACGAAAAGACTTAAAATCACTGCTGTCATGGTTCAAGCAAATGAAAGAATATAAATCGTCTAAGGAGAAAAAAGATGATGAGCCCCAAACCAATGATGAAAACGAAGAACATGAAACAAATGAGGATGCTGATACTGAAGAAGGTGATGTGGACACACAAATTGCAGAACTGCAGGATGAAGAGAAGCGACAATTGAAACGTAAAAGGAAGCAGTTGAATAAACAGAGACAAAAACTAGCTGAAAAAATGAATCTTAAGATGGTATTGAAAGGAGATGATGGTCCTATTTTGGAAAGTAATGATATGTTTCAACTCTCTGATATCAAGAATGCAGAGGAACTGAACACGCTTATAGATCAGCAGCCTGACACCGTGGTTGATGGAGATGATGCTTTTGATGATGAGATTCAACTTAAGCCAAAGTACTTGAAATACGATGTTGAGGAAACCAAGCTCGATTCATCAGGACTTTATTACAAAGATTCAGACAGTGAAATTGAAATGGAATCTGATTCAGAATCTGAACAGGAAAAAGAGTCATTAGCCTTCTCAGACTCAGACACTGAATCGAAAAAGATCAAAAAATTAACTAAATTGAATACTCTAAAAAACAGTAAAGTGAGTCCAGCAAACAAATTGAATAGATTACAGTCTATTCCAAAGAATAACCCGTTGCTCACTGATCTGGACAACACTGACCCAGTTTCGAAAAGGACTATGAAAGCTCAGCTATGGTTCGAGAAAGATTCTTTTAAAAATATTGATGAAGAAGCTGATGAAGGTATAGATTTGGACAAGTTAACAGAAACATTCAAGGAAAAAGGGAAGAAAGTCATTGAAGATGTGGAGTCAAGTAAACAAACCAGTGCACTAAAAAGAAAATTGTCAGACAACGAGAGTTCAGATGATGATTCCTCTGACAGTGATTATGATGTTGAAGAAAACGTTACTCCCAGTGCTTCTAGTGCTGGGCCAAAAGCCGGCAAAGAAGGTTTTGAAGTTGTCTCCCAAGATCCAGAACTGAAAAAACTAAAGAAAACTTTGAAAATGGACGCAGAGACACTTGCTTTAGGAACCATGATAGCTACATCAAAAAAATTCAAGAGGGATTTAATTGATGACGCGTGGAATAGATACGCGTTTAACGATAAAAACTTACCAGATTGGTTTATGGAAGATGAAAAGAAACATATGAAGAAAGACATTGTGATACCGGAGAAGTATACTGATGAATACAAGAATAGATTACAAGACATCAATGTGAGGCCTATCAAGAAGGTGATTGAAGCCAAAGCGCGGAAGAAGAAGCGCTTGATCAAAAAGATGGAACGTGCAAAGAAAAAAGTCGAGGCGGTAATGGAGAACGCTGATATGTCCGAGCGAGAGAAAGCACAACAAGTGAGACAACTTTACAAGAAGGCACAATCTGATGGTAAAAAGAAAATCACTTATGTGGTGGCCAAGAAACATACAACTGCTAAGCGTATGAAGAGACCACAGGGCGTTAAGGGCCAGTACAAAGTGGTAGATCCGCGCATGAAAAAGGACTTACGTGCCCAAAAGGCAAAGGAGAAAACAAAAGGTCGAGGTAAAAAACAACCCAAGAAACAAAACAAGCCTAAAAAAGTCCCCAAAAAGAAAGGAAAAGCAAAGTGA

Protein

MGKKTKVGKQRKDKYYQLAKETGYRSRAAFKLIQLNRKFGFLQKSRVCIDLCAAPGGWMQVAHQNMPVSSIVIGVDLFPIKPVPGCIGLTEDITTEKCKAAIKKEIKTWKADVVLNDGAPNVGLNWIHDAYQQACLTLSALKLATNFLREGGWFVTKVFRSKDYHALLWVLKQFFKKVHATKPQASRNESSEIFVVCQGYIAPDTIDPKFLDPKHVFEDLDIVKKQHINILHPEKQKKAKAEGYKENDYTTHHKVKLSDFLGKDDPVDLLHGCSEIVFDDKEIETHPKTTPEIKECCKDIKVLGRKDLKSLLSWFKQMKEYKSSKEKKDDEPQTNDENEEHETNEDADTEEGDVDTQIAELQDEEKRQLKRKRKQLNKQRQKLAEKMNLKMVLKGDDGPILESNDMFQLSDIKNAEELNTLIDQQPDTVVDGDDAFDDEIQLKPKYLKYDVEETKLDSSGLYYKDSDSEIEMESDSESEQEKESLAFSDSDTESKKIKKLTKLNTLKNSKVSPANKLNRLQSIPKNNPLLTDLDNTDPVSKRTMKAQLWFEKDSFKNIDEEADEGIDLDKLTETFKEKGKKVIEDVESSKQTSALKRKLSDNESSDDDSSDSDYDVEENVTPSASSAGPKAGKEGFEVVSQDPELKKLKKTLKMDAETLALGTMIATSKKFKRDLIDDAWNRYAFNDKNLPDWFMEDEKKHMKKDIVIPEKYTDEYKNRLQDINVRPIKKVIEAKARKKKRLIKKMERAKKKVEAVMENADMSEREKAQQVRQLYKKAQSDGKKKITYVVAKKHTTAKRMKRPQGVKGQYKVVDPRMKKDLRAQKAKEKTKGRGKKQPKKQNKPKKVPKKKGKAK

Description

Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.

Catalytic Activity

a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine

Similarity

Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.

Feature

chain  Putative rRNA methyltransferase

Uniprot

H9JWY1   A0A2H1VBU3   A0A2A4JNH1   A0A194QRF2   S4PCI3   A0A3S2NAS2   + More
A0A212ERR9   A0A194PE31   A0A154PNE2   A0A158NJW7   A0A067QZB0   E2BWY3   F4WIM5   N6TQ08   A0A195BHM4   D6X2B8   A0A195DW47   A0A026WQ43   A0A195F561   E9IMG1   A0A0L7R2X0   A0A151XE37   A0A2J7R304   E2AKJ6   A0A232FCH2   K7J012   A0A0C9QN46   A0A0C9R253   A0A088A7G6   A0A0J7KYH7   A0A151I7Y1   A0A0M8ZSQ5   A0A2A3EB54   A0A0T6B5J2   A0A310SM55   A0A1Y1MEY5   A0A1B0DPK2   A0A034WPD8   J9K0Y7   A0A1L8DX33   A0A1L8DX35   A0A0A1WMR3   A0A0N7Z9H4   A0A0K8V4M7   W8C434   A0A1A9X8R9   A0A0V0G7Y1   A0A1B0C3B3   Q17ME6   B4MA57   A0A1A9WT14   T1HXG8   A0A1A9ZEH1   A0A1Q3F1M3   B0WJS3   A0A1A9UQC1   U5EYF1   B4L6Y5   A0A1W4VGE3   A0A336L2X8   B4IMG9   Q9VXK5   A0A1Q3F1N3   A0A336MNM4   B3NXF9   A0A0Q5TK67   B4PXA9   B4JX39   A0A2M3Z119   A0A2M3ZG57   A0A182SGY5   A0A182RNS4   A0A1D2N9L0   A0A2M4A492   A0A2M4A450   A0A2M4A4X9   A0A1B3PD75   A0A182II28   A0A1B0GA10   Q7QD87   A0A2S2R6S3   A0A182G625   A0A084VC43  

EC Number

2.1.1.-

Pubmed

19121390    26354079    23622113    22118469    21347285    24845553    + More
20798317    21719571    23537049    18362917    19820115    24508170    30249741    21282665    28648823    20075255    28004739    25348373    25830018    27129103    24495485    17510324    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    27289101    12364791    14747013    17210077    26483478    24438588   

EMBL

BABH01041553    ODYU01001529    SOQ37872.1    NWSH01001013    PCG73134.1    KQ461198    + More
KPJ06116.1    GAIX01004191    JAA88369.1    RSAL01000312    RVE42665.1    AGBW02012957    OWR44159.1    KQ459606    KPI91522.1    KQ434978    KZC12984.1    ADTU01018446    KK853080    KDR11689.1    GL451188    EFN79847.1    GL888176    EGI65961.1    APGK01056102    KB741274    KB632130    ENN71340.1    ERL88981.1    KQ976465    KYM84305.1    KQ971371    EFA09884.1    KQ980304    KYN16784.1    KK107135    QOIP01000006    EZA58088.1    RLU21317.1    KQ981820    KYN35312.1    GL764146    EFZ18245.1    KQ414664    KOC65178.1    KQ982254    KYQ58625.1    NEVH01007824    PNF35206.1    GL440281    EFN66047.1    NNAY01000463    OXU28190.1    GBYB01002077    JAG71844.1    GBYB01002080    JAG71847.1    LBMM01002043    KMQ95359.1    KQ978390    KYM94299.1    KQ435918    KOX68749.1    KZ288296    PBC28920.1    LJIG01009668    KRT82620.1    KQ759878    OAD62242.1    GEZM01033160    JAV84389.1    AJVK01008144    GAKP01001501    JAC57451.1    ABLF02040185    GFDF01003071    JAV11013.1    GFDF01003067    JAV11017.1    GBXI01013993    JAD00299.1    GDKW01000539    JAI56056.1    GDHF01018460    JAI33854.1    GAMC01005769    GAMC01005767    JAC00787.1    GECL01002027    JAP04097.1    JXJN01024889    CH477206    EAT47892.1    CH940655    EDW66116.1    ACPB03008619    GFDL01013590    JAV21455.1    DS231963    EDS29416.1    GANO01000338    JAB59533.1    CH933812    EDW06131.1    UFQS01001510    UFQT01001510    SSX11313.1    SSX30881.1    CH480996    EDW46314.1    AE014298    AY069518    AAF48557.1    AAL39663.1    GFDL01013583    JAV21462.1    UFQT01001823    SSX31906.1    CH954180    EDV46918.1    KQS30246.1    CM000162    EDX01872.1    CH916376    EDV95315.1    GGFM01001454    MBW22205.1    GGFM01006714    MBW27465.1    LJIJ01000133    ODN01931.1    GGFK01002229    MBW35550.1    GGFK01002265    MBW35586.1    GGFK01002494    MBW35815.1    KU659873    AOG17672.1    APCN01000610    CCAG010018793    AAAB01008859    EAA07890.5    GGMS01016197    MBY85400.1    JXUM01147113    KQ570300    KXJ68392.1    ATLV01010166    KE524565    KFB35537.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000283053    UP000007151    UP000053268    + More
UP000076502    UP000005205    UP000027135    UP000008237    UP000007755    UP000019118    UP000030742    UP000078540    UP000007266    UP000078492    UP000053097    UP000279307    UP000078541    UP000053825    UP000075809    UP000235965    UP000000311    UP000215335    UP000002358    UP000005203    UP000036403    UP000078542    UP000053105    UP000242457    UP000092462    UP000007819    UP000092443    UP000092460    UP000008820    UP000008792    UP000091820    UP000015103    UP000092445    UP000002320    UP000078200    UP000009192    UP000192221    UP000001292    UP000000803    UP000008711    UP000002282    UP000001070    UP000075901    UP000075900    UP000094527    UP000075840    UP000092444    UP000007062    UP000069940    UP000249989    UP000030765   

PRIDE

H9JWY1    Q9VXK5   

Pfam

PF01728   FtsJ        + More
PF07780   Spb1_C
PF00067   p450
PF11861   DUF3381
PF17862   AAA_lid_3
PF00004   AAA
PF16450   Prot_ATP_ID_OB
PF03547   Mem_trans

Interpro

IPR029063   SAM-dependent_MTases        + More
IPR001128   Cyt_P450       
IPR002877   rRNA_MeTrfase_FtsJ_dom       
IPR012920   rRNA_MeTfrase_Spb1_C       
IPR015507   rRNA-MeTfrase_E       
IPR036396   Cyt_P450_sf       
IPR028589   Spb1-like       
IPR024576   rRNA_MeTfrase_Spb1_DUF3381       
IPR032501   Prot_ATP_ID_OB       
IPR041569   AAA_lid_3       
IPR003593   AAA+_ATPase       
IPR005937   26S_Psome_P45-like       
IPR003959   ATPase_AAA_core       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR004776   Mem_trans       
IPR020846   MFS_dom       

SUPFAM

SSF48264   SSF48264        + More
SSF53335   SSF53335       
SSF52540   SSF52540       

Gene 3D

1.10.630.10    

CDD

cd06174  MFS

ProteinModelPortal

H9JWY1   A0A2H1VBU3   A0A2A4JNH1   A0A194QRF2   S4PCI3   A0A3S2NAS2   + More
A0A212ERR9   A0A194PE31   A0A154PNE2   A0A158NJW7   A0A067QZB0   E2BWY3   F4WIM5   N6TQ08   A0A195BHM4   D6X2B8   A0A195DW47   A0A026WQ43   A0A195F561   E9IMG1   A0A0L7R2X0   A0A151XE37   A0A2J7R304   E2AKJ6   A0A232FCH2   K7J012   A0A0C9QN46   A0A0C9R253   A0A088A7G6   A0A0J7KYH7   A0A151I7Y1   A0A0M8ZSQ5   A0A2A3EB54   A0A0T6B5J2   A0A310SM55   A0A1Y1MEY5   A0A1B0DPK2   A0A034WPD8   J9K0Y7   A0A1L8DX33   A0A1L8DX35   A0A0A1WMR3   A0A0N7Z9H4   A0A0K8V4M7   W8C434   A0A1A9X8R9   A0A0V0G7Y1   A0A1B0C3B3   Q17ME6   B4MA57   A0A1A9WT14   T1HXG8   A0A1A9ZEH1   A0A1Q3F1M3   B0WJS3   A0A1A9UQC1   U5EYF1   B4L6Y5   A0A1W4VGE3   A0A336L2X8   B4IMG9   Q9VXK5   A0A1Q3F1N3   A0A336MNM4   B3NXF9   A0A0Q5TK67   B4PXA9   B4JX39   A0A2M3Z119   A0A2M3ZG57   A0A182SGY5   A0A182RNS4   A0A1D2N9L0   A0A2M4A492   A0A2M4A450   A0A2M4A4X9   A0A1B3PD75   A0A182II28   A0A1B0GA10   Q7QD87   A0A2S2R6S3   A0A182G625   A0A084VC43  

PDB

6EM5     E-value=6.62098e-75,     Score=717

KEGG

101737447    K14857 AdoMet-dependent rRNA methyltransferase SPB1 [EC:2.1.1.-] | (RefSeq) pre-rRNA processing prot

GO

GO:0000453   GO:0005506   GO:0016705   GO:0020037   GO:0005730   GO:0008649   GO:0005634   GO:0008168   GO:0001510   GO:0016435   GO:0031167   GO:0008650   GO:0030687   GO:0000463   GO:0000466   GO:0030163   GO:0036402   GO:0008233   GO:0005737   GO:0005524   GO:0051301   GO:0055085   GO:0016021   GO:0006364   GO:0032259   GO:0008270   GO:0003700   GO:0043565  

Subcellular location

  

Length:

855

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0536800000000001

Exp number, first 60 AAs:

0.02263

Total prob of N-in:

0.00293

outside

1  -  855

 

 

Pi

234.487055

Theta

203.875447

Tajima's D

0.615012

CLR

0.418173

CSRT

0.553122343882806

Interpretation

Uncertain