Silkworm Genome Informatics Database

Gene

KWMTBOMO05665 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014045

Annotation

PREDICTED:_DNA-directed_RNA_polymerase_III_subunit_rpc2_[Amyelois_transitella]

Location

Bomo_Chr10(+):7540093-7548156 View in EpiBrowser

Full name

DNA-directed RNA polymerase subunit beta + More
DNA-directed RNA polymerase III subunit RPC2

Alternative Name

DNA-directed RNA polymerase III 128 kDa polypeptide

Location in the cell

Nuclear Reliability : 2.571

CDS

ATGGGCGAACTTAATAAAAAACAAAATGAGTGGGATACCAAAGGATTACGGGACCCTGTCAAAACCCTTGAGGATAAATGGAAATTAGTGCCTTCATTTCTTCAAGTTAAAGGTTTGGTGAAACAGCACATAGATTCATTTAATTACTTCATAAATGTGGAGATAAAGAAGATAGTACAGGCTAATGAAAAAGTATTTTGTGAATCTGATCCACTGTTCTATATTAAATATTTAAATGCCTATGTTGGTACACCTGACTTGGAAGAAGGGTTCAATATCACTAAGCCAACGACACCTCATGAATGTCGTCTTAGAGATATAACATACTCAGCTCCTATAACTGTTGATATAGAATATATTAGAGGAAACCAGAGGGTGATCAAAAATAAACAACTGATTGGAAGAATGCCCCTCATGCTTAGGTCTTCAAACTGCGTTCTTACTAATAAATCGGATTTTGAGCTTGCACAGTTAAATGAGTGTCCCCATGATCCTGGAGGCTATTTTATTATAAGAGGTCAAGAAAAGGTGATTTTAATTCAAGAGCAACTCTCTAGAAATCGAATGATTGTTGATGAATTCAAAGGAGCAGTACAATGTCAGGTTACAAGTTCCACACATGAGAAGAAAACTAGAACGAATGTGATTCTTAAACATGGAAAATATGTGCTCAGACATAATGCATTGTCTGATGATATTCCAATAGCTGTCGCCTTTAAAGCCATGGGCATATGTAGTGATCAAGAAATAATGCAGCTTGTAGGTACTGACGATAATACAATAAAAAAAATGGCACCTTGTATTCTAGATTGCCATAATTTGAAAATATTTACTCAAAATCAAGCTCTGACTTATATAGGAAGTAAACTAAAAGTAAAAAGGTATCAAGGTGGAAACACAAAAGTACGCTCACCAATTGATGACGCTCGTGAACTATTAGCTACGACTATATTAGCTCACGTATCGGTTGAGAATTACAATTTCTACGTAAAGGCCATTTACCTTGCGATAATGGTGAAAAGGGTAATTGAAGCCGAAACAAATAAAACTGCAATAGACGATCCAGATTACTATGGGAACAAAAGGCTTGAATTGGCGGGGTCTTTATTGGCACTTATGTTTGAAGATTTATTCAAAAGATTCAACTGGGAATTGAAGAGTATAGCCGATAAAATAATACCTAAAGTTAAAGCTGCCCCCTTTGATGTTGTGAAGCATATGAGACCGGATTTGATTGCTAATGGACTGTTTACAGCCATCTCTAGTGGCAATTGGACAATTAAGCGCTTTAAAATGGAAAGGCACGGGGTCACACAAGTATTAAGTCGCCTCAGTTATATATCAGCACTTGGTATGATGACAAGAGTAAATTCCCAATTCGAGAAGACCAGAAAAGTGTCTGGACCACGGTCATTACAGGCCTCACAGTGGGGTATGCTGTGTCCTTCCGACACTCCTGAAGGAGAAGCATGCGGTCTTGTTAAGAATTTAGCACTTATGACGCATATTACAACAGAGTGTTCTGAAGAGCCTATTGCTAAGTTGGCCTGTAATGCTGGAGTTGAAGACGTAAGGCTGCTAGGCGGAGAAGAAATAAATCATCCTGCTGTTTACATTGTCTTTCTTAATGGTAACATACTGGGCGTTTCTCGACAGTATAAGCGGCTGATTAAAGTTTTTAGAATGTTCAGGAGAAGAGGATTGATTTCAGCTTTTGTCTCCATATATCCCAATCATAACCAAAGAACCGTTTATATCTGCAGTGACGGCGGCAGGCTCTGTCGACCGTACATAATCGTAGAAAGAGGAAATACCTTAGTGCAGCAATCTCATTTAAATGAATTAAATAGAGGTATAAGAAAATTCCAAGATTTCTTAAATGATGGTCTTATAGAATATTTGGATGTAAATGAAGAAAATGACAGTCATATAGCAACACGTGAAGTAGATATTGATCCGTACGTCACTACTCATCTAGAAATAGAACCTTTTACGATATTAGGTGTGTGCGCAGGCTTAGTACCATATCCACATCACAACCAGAGCCCTAGGAACACATATCAATGTGCTATGGGTAAACAAGCAATGGGAACCATAGGGTACAATCAAAAAAACAGAATCGATACTCTAATGTATAACCTTGTTTATCCTCAATGTCCAATGGTGAAGTCTAAAACTATTGAGTTGATAAATTTTGATAAACTGCCAGCTGGTCAGAACGCTACTGTCGCTGTAATGAGCTACAGTGGATATGATATAGAAGACGCTTTGATTCTAAACAAAGCTTCGATTGACAGAGGATATGGACGTTGTCTAGTTTATAAAAGTGCGAAAACAACAATGAAGCGGTACAGCAATCAAACATCGGACCGAATTTTGGGACCTTCGAGAGATGCAGTTACAGGAAAAGTAATTAGAACTCATGATGTTTTGGATTCTGACGGCATTGCAGCTCCAGGTGAAATGGTTGAAAATAGGCAAGTTTTAATAAACAAACAGATGCCGCCGGCTACGATAAATCCCGTCACTCAAGGACAACCGCAACAAATTGAATACAAAGATGTACCAGTTACATACAAAGGGCCAGTTGAGTCATACATCGAAAAGGTTATGGTATCTTCAAACTCCGAAGATGCTTTCTTGATAAAAATCTTATTAAGGCAAACCAGAGTTCCAGAGATCGGTGACAAGTTTAGTTCTAGACACGGTCAGAAAGGTGTAACTGGCTTGATTGTGCAACAAGAAGATATGCCTTTTAATGACAGAGGAATATGTCCTGACATGATCATGAATCCCCACGGCTTCCCATCTAGAATGACAGTGGGAAAAACCATTGAGCTCTTAGCTGGAAAAGCGGGATTATTAGAAGGAAAATTCCATTATGGTACTGCGTTCGGAGGTTCCAAAGTACAGGACGTTTGCAAAGAATTAGAAAAACATGGTTACAATTATCACGGAAAAGATATATTTTATTCGGGATTAACTGGAGAGCCTTTAGAAGCTTATATTTATTCTGGTCCTGTATACTACCAGAAGTTAAAGCATATGGTTCAAGACAAAATGCACGCCCGAGCACGCGGACCTAGGGCGGTTCTGACTCGTCAACCGACTGAAGGACGCTCTCGCGACGGAGGACTTCGGCTGGGCGAGATGGAACGAGATTGTCTTATTGGATATGGCGCCAGCATGTTGATCATGGAGCGGCTAATGCTGGCCTCGGACGCGTTCACCGCGGACATATGCGGCGCGTGCGGGCGGCTCGCGAACCGCGCCTGGTGTCACACTTGCCGGTCATCGGCTGCGGTTTCCAGTGTCGAAATGCCGTACGCTTGCAAATTGTTATTTCAAGAACTAGCTTCAATGAATATCGTACCTAAGCTTACCCTAAAGAAATATTCCTAA

Protein

MGELNKKQNEWDTKGLRDPVKTLEDKWKLVPSFLQVKGLVKQHIDSFNYFINVEIKKIVQANEKVFCESDPLFYIKYLNAYVGTPDLEEGFNITKPTTPHECRLRDITYSAPITVDIEYIRGNQRVIKNKQLIGRMPLMLRSSNCVLTNKSDFELAQLNECPHDPGGYFIIRGQEKVILIQEQLSRNRMIVDEFKGAVQCQVTSSTHEKKTRTNVILKHGKYVLRHNALSDDIPIAVAFKAMGICSDQEIMQLVGTDDNTIKKMAPCILDCHNLKIFTQNQALTYIGSKLKVKRYQGGNTKVRSPIDDARELLATTILAHVSVENYNFYVKAIYLAIMVKRVIEAETNKTAIDDPDYYGNKRLELAGSLLALMFEDLFKRFNWELKSIADKIIPKVKAAPFDVVKHMRPDLIANGLFTAISSGNWTIKRFKMERHGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQASQWGMLCPSDTPEGEACGLVKNLALMTHITTECSEEPIAKLACNAGVEDVRLLGGEEINHPAVYIVFLNGNILGVSRQYKRLIKVFRMFRRRGLISAFVSIYPNHNQRTVYICSDGGRLCRPYIIVERGNTLVQQSHLNELNRGIRKFQDFLNDGLIEYLDVNEENDSHIATREVDIDPYVTTHLEIEPFTILGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGTIGYNQKNRIDTLMYNLVYPQCPMVKSKTIELINFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKSAKTTMKRYSNQTSDRILGPSRDAVTGKVIRTHDVLDSDGIAAPGEMVENRQVLINKQMPPATINPVTQGQPQQIEYKDVPVTYKGPVESYIEKVMVSSNSEDAFLIKILLRQTRVPEIGDKFSSRHGQKGVTGLIVQQEDMPFNDRGICPDMIMNPHGFPSRMTVGKTIELLAGKAGLLEGKFHYGTAFGGSKVQDVCKELEKHGYNYHGKDIFYSGLTGEPLEAYIYSGPVYYQKLKHMVQDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLIMERLMLASDAFTADICGACGRLANRAWCHTCRSSAAVSSVEMPYACKLLFQELASMNIVPKLTLKKYS

Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Subunit

Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.

Similarity

Belongs to the RNA polymerase beta chain family.

Keywords

Complete proteome DNA-directed RNA polymerase Metal-binding Nucleotidyltransferase Nucleus Reference proteome Transcription Transferase Zinc Zinc-finger

Feature

chain DNA-directed RNA polymerase III subunit RPC2

Uniprot

H9JWY0 A0A2H1VAK1 A0A2A4JN27 A0A194QRF9 A0A194PE38 A0A212ERT5 + More
A0A2J7QQY1 A0A067R2B0 A0A1I8M264 A0A0A1X7E2 W8BZF1 A0A1I8Q9N0 A0A0K8V9X3 A0A0L0CE46 A0A1A9WS20 A0A1A9VV63 A0A1B0GEW0 A0A1A9ZM86 A0A1A9YBN1 A0A1B0AVC9 A0A182YQY1 J9E9F1 A0A182M006 A0A182NUG7 A0A2J7QQZ4 A0A182QGE6 A0A2J7QQX9 A0A182GK95 A0A084W850 A0A182RCS3 A0A1J1IJL9 A0A182W702 A0A182PPL3 A0A1Q3G0W3 A0A182U227 A0A1S4GY45 A0A182F4X6 A0A182V8B9 A0A182WTZ8 A0A182HUL4 W5JC11 A0A182L1C8 A0A182JPP2 A0A0N0BBY3 B3MH37 B4P5Q3 A0A1B6H3M6 A0A2M4BB50 A0A154NZN5 B3NS93 A0A088AHH9 B4HNX0 B4QC69 P25167 A0A1W4UAH4 A0A0L7RIW8 B4LKV4 A0A336KW81 A0A0M4EW33 B4J5G6 B4KPU7 A0A1B0GK01 A0A2A3EA13 A0A1B6DRA4 B4GGQ4 Q28ZV6 A0A3B0J1G6 A0A232F5C0 K7IUQ9 A0A069DXS3 A0A0V0G733 A0A023F4Q9 D6WK19 A0A0T6AUA8 A0A0K8TFV3 A0A1Y1MDV1 A0A218UWX9 U3KG47 H3BBW8 A0A3L8SDE3 A0A3B4E4L5 A0A151NHZ7 A0A1V4K7J8 H0ZLB7 A0A1W4ZT72 E1BRJ4 A0A3B1INH5 A0A3B3QZG5 A0A3Q2Z3I4 A0A2U9BX06 W5UJ75 G3PDG5 A0A250Y706 A0A3Q3IXG8 F1QQA2 H0XBX4 G1KR53 A0A2U3ZYU7 A0A340WPV6 H2TAU9

EC Number

2.7.7.6

Pubmed

19121390 26354079 22118469 24845553 25315136 25830018 + More
24495485 26108605 25244985 17510324 26483478 24438588 12364791 20920257 23761445 20966253 17994087 17550304 22936249 1910149 10731132 12537572 12537569 15632085 28648823 20075255 26334808 25474469 18362917 19820115 26823975 28004739 9215903 30282656 22293439 20360741 15592404 25329095 29240929 23127152 28087693 23594743 21551351

EMBL

BABH01041550 BABH01041551 ODYU01001529 SOQ37868.1 NWSH01001013 PCG73128.1 + More
KQ461198 KPJ06121.1 KQ459606 KPI91527.1 AGBW02012957 OWR44164.1 NEVH01012082 PNF30992.1 KK853069 KDR11828.1 GBXI01007694 JAD06598.1 GAMC01011946 JAB94609.1 GDHF01016974 JAI35340.1 JRES01000501 KNC30683.1 CCAG010012601 JXJN01004196 CH477269 EJY57481.1 AXCM01013681 PNF30993.1 AXCN02000760 PNF30994.1 JXUM01069618 JXUM01069619 KQ562560 KXJ75626.1 ATLV01021362 KE525317 KFB46394.1 CVRI01000048 CRK98641.1 GFDL01001639 JAV33406.1 AAAB01008964 APCN01002465 ADMH02001944 ETN60389.1 KQ435969 KOX67898.1 CH902619 EDV35796.1 CM000158 EDW90850.1 GECZ01000521 JAS69248.1 GGFJ01001116 MBW50257.1 KQ434786 KZC05087.1 CH954179 EDV56395.1 CH480816 EDW47485.1 CM000362 CM002911 EDX06700.1 KMY93081.1 X58826 AE013599 AY121645 KQ414583 KOC70753.1 CH940648 EDW60758.1 UFQS01001076 UFQT01001076 SSX08858.1 SSX28769.1 CP012524 ALC42212.1 CH916367 EDW00729.1 CH933808 EDW10224.1 AJWK01022481 KZ288310 PBC28613.1 GEDC01009082 JAS28216.1 CH479183 EDW35674.1 CM000071 EAL25506.1 OUUW01000001 SPP75044.1 NNAY01000902 OXU26004.1 AAZX01002639 AAZX01002655 GBGD01000204 JAC88685.1 GECL01002302 JAP03822.1 GBBI01002729 JAC15983.1 KQ971342 EFA03935.1 LJIG01022803 KRT78630.1 GBRD01001422 GDHC01020379 JAG64399.1 JAP98249.1 GEZM01035540 GEZM01035539 JAV83188.1 MUZQ01000103 OWK58334.1 AGTO01000071 AGTO01020310 AFYH01029739 AFYH01029740 AFYH01029741 AFYH01029742 AFYH01029743 AFYH01029744 AFYH01029745 AFYH01029746 QUSF01000028 RLW00111.1 AKHW03002956 KYO36427.1 LSYS01004200 OPJ80440.1 ABQF01016147 ABQF01016148 ABQF01016149 AADN05000523 CP026252 AWP08641.1 JT415560 AHH41740.1 GFFV01000582 JAV39363.1 BX465207 BX572646 AAQR03016506 AAQR03016507 AAQR03016508 AAQR03016509

Proteomes

UP000005204 UP000218220 UP000053240 UP000053268 UP000007151 UP000235965 + More
UP000027135 UP000095301 UP000095300 UP000037069 UP000091820 UP000078200 UP000092444 UP000092445 UP000092443 UP000092460 UP000076408 UP000008820 UP000075883 UP000075884 UP000075886 UP000069940 UP000249989 UP000030765 UP000075900 UP000183832 UP000075920 UP000075885 UP000075902 UP000069272 UP000075903 UP000076407 UP000075840 UP000000673 UP000075882 UP000075881 UP000053105 UP000007801 UP000002282 UP000076502 UP000008711 UP000005203 UP000001292 UP000000304 UP000000803 UP000192221 UP000053825 UP000008792 UP000092553 UP000001070 UP000009192 UP000092461 UP000242457 UP000008744 UP000001819 UP000268350 UP000215335 UP000002358 UP000007266 UP000197619 UP000016665 UP000008672 UP000276834 UP000261440 UP000050525 UP000190648 UP000007754 UP000192224 UP000000539 UP000018467 UP000261540 UP000264820 UP000246464 UP000221080 UP000007635 UP000261600 UP000000437 UP000005225 UP000001646 UP000245320 UP000265300 UP000005226

PRIDE

H9JWY0 P25167

Pfam

PF00562   RNA_pol_Rpb2_6        + More
PF04561   RNA_pol_Rpb2_2
PF04565   RNA_pol_Rpb2_3
PF04567   RNA_pol_Rpb2_5
PF04563   RNA_pol_Rpb2_1
PF04560   RNA_pol_Rpb2_7
PF04566   RNA_pol_Rpb2_4

Interpro

IPR037033   DNA-dir_RNAP_su2_hyb_sf        + More
IPR007645   RNA_pol_Rpb2_3
IPR007646   RNA_pol_Rpb2_4
IPR007641   RNA_pol_Rpb2_7
IPR007644   RNA_pol_bsu_protrusion
IPR037034   RNA_pol_Rpb2_2_sf
IPR014724   RNA_pol_RPB2_OB-fold
IPR007642   RNA_pol_Rpb2_2
IPR007120   DNA-dir_RNAP_su2_dom
IPR015712   DNA-dir_RNA_pol_su2
IPR007647   RNA_pol_Rpb2_5
IPR007121   RNA_pol_bsu_CS

Gene 3D

2.40.270.10 2.40.50.150 3.90.1110.10

CDD

cd00653 RNA_pol_B_RPB2

ProteinModelPortal

H9JWY0 A0A2H1VAK1 A0A2A4JN27 A0A194QRF9 A0A194PE38 A0A212ERT5 + More
A0A2J7QQY1 A0A067R2B0 A0A1I8M264 A0A0A1X7E2 W8BZF1 A0A1I8Q9N0 A0A0K8V9X3 A0A0L0CE46 A0A1A9WS20 A0A1A9VV63 A0A1B0GEW0 A0A1A9ZM86 A0A1A9YBN1 A0A1B0AVC9 A0A182YQY1 J9E9F1 A0A182M006 A0A182NUG7 A0A2J7QQZ4 A0A182QGE6 A0A2J7QQX9 A0A182GK95 A0A084W850 A0A182RCS3 A0A1J1IJL9 A0A182W702 A0A182PPL3 A0A1Q3G0W3 A0A182U227 A0A1S4GY45 A0A182F4X6 A0A182V8B9 A0A182WTZ8 A0A182HUL4 W5JC11 A0A182L1C8 A0A182JPP2 A0A0N0BBY3 B3MH37 B4P5Q3 A0A1B6H3M6 A0A2M4BB50 A0A154NZN5 B3NS93 A0A088AHH9 B4HNX0 B4QC69 P25167 A0A1W4UAH4 A0A0L7RIW8 B4LKV4 A0A336KW81 A0A0M4EW33 B4J5G6 B4KPU7 A0A1B0GK01 A0A2A3EA13 A0A1B6DRA4 B4GGQ4 Q28ZV6 A0A3B0J1G6 A0A232F5C0 K7IUQ9 A0A069DXS3 A0A0V0G733 A0A023F4Q9 D6WK19 A0A0T6AUA8 A0A0K8TFV3 A0A1Y1MDV1 A0A218UWX9 U3KG47 H3BBW8 A0A3L8SDE3 A0A3B4E4L5 A0A151NHZ7 A0A1V4K7J8 H0ZLB7 A0A1W4ZT72 E1BRJ4 A0A3B1INH5 A0A3B3QZG5 A0A3Q2Z3I4 A0A2U9BX06 W5UJ75 G3PDG5 A0A250Y706 A0A3Q3IXG8 F1QQA2 H0XBX4 G1KR53 A0A2U3ZYU7 A0A340WPV6 H2TAU9

PDB

6F44 E-value=0, Score=3404

KEGG

101737159 K03021 DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6] | (RefSeq) DNA-directed RNA polymer

PATHWAY

03020 RNA polymerase - Bombyx mori (domestic silkworm)

GO

GO:0003677 GO:0003899 GO:0032549 GO:0006351 GO:0005634 GO:0046872 GO:0006383 GO:0005666 GO:0045089 GO:0032728 GO:0048565 GO:0031017 GO:0009304 GO:0005739 GO:0007005 GO:0031307 GO:0008270 GO:0003700 GO:0043565

PANTHER

PTHR20856

Subcellular location

Nucleus

Length:

1133

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04466

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00031

outside

1 - 1133

Pi

269.919205

Theta

199.714929

Tajima's D

1.219365

CLR

0.014645

CSRT

0.720913954302285

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics