Gene

KWMTBOMO05636  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006548

Annotation

PREDICTED:_tetratricopeptide_repeat_protein_37_[Papilio_xuthus]

Location

Bomo_Chr10(-):7002481-7006442      View in EpiBrowser

Full name

Tetratricopeptide repeat protein 37      

Alternative Name

SKI3 homolog
Tricho-hepatic-enteric syndrome protein

Location in the cell

Nuclear   Reliability : 1.931

CDS

ATGGCTGATATTAAACAACTGTTGAAGGAGGCAAGGAAGCATATTGATGAAAAAAATTACAAAGATGCTCAAGAGTGCTGTAAAAACCTCCTTAGAAAAGATAAACAAAACTATTTTGGGTTAGTGTTACTAGGTAAATCCTTCCAAGATTCTGACCAGGCGTGTTTAGCATATCAAAAAGCAATTGCATGTAAACCCAGTCACCCCTTAGCTTGGCTAGGATTAGCCAGCTATTATGAAGCCCATGACGATCAAATCATGAATGTTAAACTACTCCCCGTATATGTTGAAATATTAAAATTACAAATTGAAGAGGAGAAAGCTCTCGAAATCATTTCGAAAATCGGAAAGTTAGGAGTTAGATACAAAAATGGTGATGTTGTTGAAACTTTAATAAATTATCTTAAAGAAGAACCACCAACGACTTTACGTAAATCAGCTGAAGAGCAATTGATCTGTCTTATTAATGAAAATATACCTTGTGGAGAACCAATTATACCTGCTCTTTTGGAAATCTTACCTAAACTAATAACCACATCATCCGATCAAAATGAATTATTGCAAAGTAAAATCATACTGCAAAAAACTAATTTTTCTTTAGCAGTGGAGGAAATTATTGAGAAAAGTTATTTCAAAGAAAATATTGTTGTGAGAGAATGGCTTTGCAATCAATTGTGTAAAAAATATGTAGAGAACATGTGTTTTTTTGGTTTGGATATAGAGAAACATATAGAAACCATTATTTCTGGAGTTGTGAACTCCAAATATCCAGATCTTTTGAAGAGTATGATTGCCTTTGAGAAAGGTTTTTATTTAGATGCATACAAATTTTCTGTTCCTCTCATTAATTACCATGAACCAGAATTTACTGAGGGAATTTTTATTATAAAATGTACTATGAAGCTTCAAAAATGGTCTGTAGCTCAAAAACTAGCAACAAATTTTTTAACAAAAGTTAAGGATTCTAGATTTTGCTTAGAATTGAATAAAAATTTATTTTACTCTTTAGTAAAACAACAAAAATGGCAATCTGCACTATTGGTTTCAAAAAATATACAAAAGAATTCACACAGTATTCAAGATTCATTCAATGTTGATGAGCTTGCATCAGTGGTGGAGTGTTTGATTGAAGTAGGTGAACCATTTGATGATTTATTGAATGAATTACAGTCTACAAATTATTATGAATCTTTGAAGGCATTATCTTTTTTAAAACAAGGTAAATTTGATGATGTTGTAAATTTACTTCAAAACAGCAATCTAGAAAATTCAATTAATGTTTTTTATTTGGGTAAGGCATATTGGGAACTTAAAAAATATAATGAAGCACTTTTAAATCTGCTAAAATCTGCAAGATTGAATTCTGAACATTTTGAAACATTTATATATTTAGGACATTTTTACTATCACACCAAAAATGACTTACTTAAGGCAAAAAAGTGTTATGAAAAGGCTTATAGCTTAAATAATCTTGATGGCAACTTACTCAGAAGTTTAAGTGATGTTTATTTAAAACTAAAACTTACTGACATGGATTTTGAAATGTTGACCACAATTTCAAAAACTACAAATGAATCATGGATTCATTTTAGGCTTGGATTACATTACTTAAATAGAAAAGAATGGGAAAATGCTATCACATATTTTAGAAACGTTGTTAAGATCAACCAGAATGATACAACAGCATTTGAATGTTTAGCAGATGCATATTACTGCCGTGGTTCATATACCTCTGCATTGAAAGCATATAATAGGTTATTGACACTAGATCCAAATAAAGCTATCCATTGTCTAACAAGGAGTGGATATATATTTTCACTTTTAACACAGCATGAAGAAGCTATTTGCACTTTTCAGAAAGTTCTTTCAATGGATCCCAATTGTATTTTAGCTGTGAAGGGAATTGCAGAAACATGGATAAGAATATCTAAGAAGAAAATAGCAGCAAAAGTTTTTGGTAGCGCTAGAGATTGTGCCCAGAAAGCTGTTGATTATTTAACAGATGTATTAGAGAAACAAACAAATAAACAATTTACTTGTTTATGGAAACTATTAGGAGACACATTGATTATGGTAACAAAATTACCTATGAAATATGCATATATTTATATGAGTGAACTTTCAAATGAATCTGTTAAAGTTAAAAAGGAGCTCTTGGATATATTTTCAGAAGCAATTAAATGTTATTCATATATTTCTAAACAAAAGCAACAATTTGCTTCTTATGATTTGGCTACCACCTATTTAGCTTATTATAACGTAACTAAGAAAGTTGTGAATTGCCATATAGCTTTTAATTTGACCATGACATGCATTAAAGAAAAACCACAACACTGGCGTAGTTGGAATTTACTGGGAAAAATTGGTTTATATGTTAAGAAATATGAAATTGCACAACATTGTTTCATAAAAGCTTTGTTATCCACAAGAAAATGGTCAGTGGCAAAGATATGGTGCAACCTTGGTACACTGTATTTAAAATTAAAACTTTATAGATTGGCCAATTATTGTTTTTGGCGTGGACAATCTACTTTACCATCATATCCCCATAGTTGGATAGGTCAAGGTTTGATAGCAGAAGTCATAAGGGAAGAGGAAGCAATGGATCTGTTCAGACATGCATCCCGCTTAGGTTACCATTCTGAAAGTGCACTAGCATATGCAGATTGGGTTTGTCGTGTGTTTAACAACAAAAAATATCAGGAAGACCCTGAATATAAATATGAGATTCAAGGTCTTTATGCAGTCACTTGTGCCATGGATCTGATGCAGTGGTTTTGCGACTTTGATTCAAAGAATCCTTGTGCTTTAACAATTCTAGGAATCTTACAAGAACAAAGTTTACTTCTACGAAGTGCTCTAAAATCATATGAGAAAGCTTTACAGTATTGTGAAGGAGATAAAAAGAACATAGCACTTCTAAATATGGGAAGGATTTTGACAAGAATGGGAAATTATGATGATGCTATCAATGCCTATAAATCAATTACAGAAGCTAGTCTAAATTCTACAACTGGTTTAGCTTTAGCTTTATTCAAGAAGGGATTTTTTGAAGAGGCCTATTCTGCATATGAGACTGCTTTACAATGGCTCAGTGAAACCGATGAAGATAAGGCAGATCTCCTTGTGGCTATGGCTAGTTCTGTATATACACAGAAAGGAGTAAATGACACAAAAACGCTACTCTTTCGGAGTATACAAGCTTCCCAGAAAAAACCCACAGCTCACAGTTTGTTTGCAGTTTGCTCTTTAGGACTTTTACATGCAGATAAAAGTTTATCCAAATTAGCAATATGTGAAATGCAGAAGTATGATAAGGATGATGAATTTGTTTTCGATATTGGTTTCCTAAAATCTTACTTGCATGTATATGACGAAAATATGAACCAAGCAACCAAATTTCTGAGCGATTCTCTGCATGATTTTCCAAGTAATGCTCTACTGTGGTTTTGCATGGCACAATATTGTCTTATGGAGACAAATCTTAAGGCCAAAGTTTCTAGCCGATGTTCGCAAAGGGCATTGAGTTTAGCTCAAAATAATGAAAGCAATATTAATCTTGCTAAATTAATAGCCACAGCGAGCGTAGCTGAATTTATAGCAGGAGATCGTGTAAGAGCTTTTATATTAGCAAAACAAGGTTTACATCTATTTCCATGTCAACCAGAAATATGGGCTGCAGTATTACGTTCTCTTGTATCCCATAAAATATGGTTGTTTAAAAAACCATGTATTATGAGAATAACAGATTTTATGCGTAAAAATTTAAATATATCGCGTCGTCTTGCTAAGTGGATCACTCTGGTAGAAAAAAAATTAAGTAGGTAG

Protein

MADIKQLLKEARKHIDEKNYKDAQECCKNLLRKDKQNYFGLVLLGKSFQDSDQACLAYQKAIACKPSHPLAWLGLASYYEAHDDQIMNVKLLPVYVEILKLQIEEEKALEIISKIGKLGVRYKNGDVVETLINYLKEEPPTTLRKSAEEQLICLINENIPCGEPIIPALLEILPKLITTSSDQNELLQSKIILQKTNFSLAVEEIIEKSYFKENIVVREWLCNQLCKKYVENMCFFGLDIEKHIETIISGVVNSKYPDLLKSMIAFEKGFYLDAYKFSVPLINYHEPEFTEGIFIIKCTMKLQKWSVAQKLATNFLTKVKDSRFCLELNKNLFYSLVKQQKWQSALLVSKNIQKNSHSIQDSFNVDELASVVECLIEVGEPFDDLLNELQSTNYYESLKALSFLKQGKFDDVVNLLQNSNLENSINVFYLGKAYWELKKYNEALLNLLKSARLNSEHFETFIYLGHFYYHTKNDLLKAKKCYEKAYSLNNLDGNLLRSLSDVYLKLKLTDMDFEMLTTISKTTNESWIHFRLGLHYLNRKEWENAITYFRNVVKINQNDTTAFECLADAYYCRGSYTSALKAYNRLLTLDPNKAIHCLTRSGYIFSLLTQHEEAICTFQKVLSMDPNCILAVKGIAETWIRISKKKIAAKVFGSARDCAQKAVDYLTDVLEKQTNKQFTCLWKLLGDTLIMVTKLPMKYAYIYMSELSNESVKVKKELLDIFSEAIKCYSYISKQKQQFASYDLATTYLAYYNVTKKVVNCHIAFNLTMTCIKEKPQHWRSWNLLGKIGLYVKKYEIAQHCFIKALLSTRKWSVAKIWCNLGTLYLKLKLYRLANYCFWRGQSTLPSYPHSWIGQGLIAEVIREEEAMDLFRHASRLGYHSESALAYADWVCRVFNNKKYQEDPEYKYEIQGLYAVTCAMDLMQWFCDFDSKNPCALTILGILQEQSLLLRSALKSYEKALQYCEGDKKNIALLNMGRILTRMGNYDDAINAYKSITEASLNSTTGLALALFKKGFFEEAYSAYETALQWLSETDEDKADLLVAMASSVYTQKGVNDTKTLLFRSIQASQKKPTAHSLFAVCSLGLLHADKSLSKLAICEMQKYDKDDEFVFDIGFLKSYLHVYDENMNQATKFLSDSLHDFPSNALLWFCMAQYCLMETNLKAKVSSRCSQRALSLAQNNESNINLAKLIATASVAEFIAGDRVRAFILAKQGLHLFPCQPEIWAAVLRSLVSHKIWLFKKPCIMRITDFMRKNLNISRRLAKWITLVEKKLSR

Subunit

Component of the SKI complex which consists of WDR61, SKIV2L and TTC37. Interacts with PAF1.

Keywords

Acetylation   Complete proteome   Cytoplasm   Nucleus   Polymorphism   Reference proteome   Repeat   TPR repeat  

Feature

chain  Tetratricopeptide repeat protein 37
sequence variant  In THES1; dbSNP:rs763816083.

Uniprot

H9JAK3   A0A2A4J7G2   A0A2H1VU05   A0A212EUL6   A0A0L7LFY2   A0A139WFG6   + More
E9IM07   A0A067QUE4   A0A151XCS2   A0A151I048   A0A158NC66   A0A195F9Y1   A0A195EAR2   A0A151I7Y8   A0A1W4WL79   F4WYV6   A0A1Y1NGX9   A0A026WTF8   A0A3L8DFL2   A0A088A9A0   E2AYS8   E0VHH7   A0A0C9QMZ3   A0A232F6D3   A0A0M9A540   A0A154PKG3   A0A1B6C264   E2B5B3   B0W3M1   A0A1J1I5U7   A0A0P6ITD0   A0A034VGT4   A0A0L0BSN6   A0A1I8P3W2   A0A0K8W5G5   A0A182IZI8   A0A0A1XE18   A0A1A9WAC9   A0A1I8N892   Q7QKK1   A0A182GQB6   A0A182HJE0   A0A182MW67   A0A1I8N8B2   A0A182TJE0   A0A182X1X2   A0A182JS18   A0A182V1D7   W8BBM6   A0A1B6EF92   A0A182VQN4   T1PH44   A0A0K8U8U2   A0A182QN41   A0A182N562   A0A2M4CZT0   A0A336LKS6   A0A182YK83   A0A182PIB7   A0A3B0J4I9   B4ME29   A0A182RHW6   B4J7V9   A0A341BJ04   A0A0D9RPU6   A0A2I3LM63   A0A3B0J0H1   A0A2I3MKI1   Q6PGP7   A0A2K5M519   A0A2R9AW40   F7DAC0   A0A2K5W236   G7MVA9   I2CUB2   A0A2K6R2B0   A0A2K5I6A7   H9EW22   B3MI76   A0A2K5Z6C4   A0A0P6J8B0   A0A2Y9PRZ3   A0A2Y9PYF0   A0A1S3J9U5   G5BU34   A0A2J8TDB7   A0A3Q2GV14   F6QDG2   A0A0P9ACT4   A0A1S3JAF0   A0A1W4UXL2  

Pubmed

19121390    22118469    26227816    18362917    19820115    21282665    + More
24845553    21347285    21719571    28004739    24508170    30249741    20798317    20566863    28648823    26999592    25348373    26108605    25830018    25315136    12364791    14747013    17210077    26483478    24495485    25244985    17994087    9205841    15489334    16024656    21269460    21120949    22814378    24275569    20176027    22722832    17431167    22002653    25319552    25362486    21993625    19892987   

EMBL

BABH01008785    NWSH01002591    PCG67901.1    ODYU01004435    SOQ44303.1    AGBW02012332    + More
OWR45200.1    JTDY01001231    KOB74463.1    KQ971352    KYB26666.1    GL764129    EFZ18450.1    KK852942    KDR13502.1    KQ982298    KYQ58165.1    KQ976642    KYM78663.1    ADTU01011668    KQ981727    KYN37181.1    KQ979236    KYN22196.1    KQ978417    KYM94057.1    GL888463    EGI60610.1    GEZM01007779    GEZM01007778    JAV94937.1    KK107109    EZA59238.1    QOIP01000008    RLU19184.1    GL443983    EFN61441.1    DS235170    EEB12833.1    GBYB01002027    GBYB01012088    JAG71794.1    JAG81855.1    NNAY01000895    OXU26033.1    KQ435732    KOX77417.1    KQ434946    KZC12335.1    GEDC01029844    JAS07454.1    GL445814    EFN89108.1    DS231832    EDS31807.1    CVRI01000042    CRK95703.1    GDUN01000942    JAN94977.1    GAKP01017947    JAC41005.1    JRES01001423    KNC22993.1    GDHF01005866    JAI46448.1    GBXI01005085    JAD09207.1    AAAB01008794    EAA03563.5    JXUM01080247    JXUM01080248    KQ563175    KXJ74333.1    APCN01002154    AXCM01001650    GAMC01010483    JAB96072.1    GEDC01000747    JAS36551.1    KA648137    AFP62766.1    GDHF01029579    JAI22735.1    AXCN02000174    GGFL01006629    MBW70807.1    UFQT01000040    SSX18642.1    OUUW01000001    SPP74433.1    CH940662    EDW58794.2    CH916367    EDW01165.1    AQIB01087029    AHZZ02029527    AHZZ02029528    SPP74434.1    AB002370    BC015163    BC056893    AJFE02079404    AJFE02079405    AJFE02079406    AJFE02079407    JSUE03036464    AQIA01059664    AQIA01059665    JV048805    CM001258    AFI38876.1    EHH26670.1    JV565212    AFJ70547.1    JU322825    JU477965    AFE66581.1    AFH34769.1    CH902619    EDV35921.1    GEBF01003831    JAN99801.1    JH171888    EHB12795.1    NDHI03003507    PNJ30979.1    KPU75888.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000037510    UP000007266    UP000027135    + More
UP000075809    UP000078540    UP000005205    UP000078541    UP000078492    UP000078542    UP000192223    UP000007755    UP000053097    UP000279307    UP000005203    UP000000311    UP000009046    UP000215335    UP000053105    UP000076502    UP000008237    UP000002320    UP000183832    UP000037069    UP000095300    UP000075880    UP000091820    UP000095301    UP000007062    UP000069940    UP000249989    UP000075840    UP000075883    UP000075902    UP000076407    UP000075881    UP000075903    UP000075920    UP000075886    UP000075884    UP000076408    UP000075885    UP000268350    UP000008792    UP000075900    UP000001070    UP000252040    UP000029965    UP000028761    UP000005640    UP000233060    UP000240080    UP000006718    UP000233100    UP000233200    UP000233080    UP000007801    UP000233140    UP000248483    UP000085678    UP000006813    UP000002281    UP000192221   

PRIDE

H9JAK3    Q6PGP7   

Pfam

PF13181   TPR_8        + More
PF13176   TPR_7
PF09295   ChAPs
PF07719   TPR_2
PF13174   TPR_6

Interpro

IPR013026   TPR-contain_dom        + More
IPR019734   TPR_repeat       
IPR039226   Ski3/TTC37       
IPR011990   TPR-like_helical_dom_sf       
IPR015374   ChAPs       
IPR013105   TPR_2       
IPR003107   HAT       
IPR006597   Sel1-like       

SUPFAM

SSF48452   SSF48452       

Gene 3D

1.25.40.10    

ProteinModelPortal

H9JAK3   A0A2A4J7G2   A0A2H1VU05   A0A212EUL6   A0A0L7LFY2   A0A139WFG6   + More
E9IM07   A0A067QUE4   A0A151XCS2   A0A151I048   A0A158NC66   A0A195F9Y1   A0A195EAR2   A0A151I7Y8   A0A1W4WL79   F4WYV6   A0A1Y1NGX9   A0A026WTF8   A0A3L8DFL2   A0A088A9A0   E2AYS8   E0VHH7   A0A0C9QMZ3   A0A232F6D3   A0A0M9A540   A0A154PKG3   A0A1B6C264   E2B5B3   B0W3M1   A0A1J1I5U7   A0A0P6ITD0   A0A034VGT4   A0A0L0BSN6   A0A1I8P3W2   A0A0K8W5G5   A0A182IZI8   A0A0A1XE18   A0A1A9WAC9   A0A1I8N892   Q7QKK1   A0A182GQB6   A0A182HJE0   A0A182MW67   A0A1I8N8B2   A0A182TJE0   A0A182X1X2   A0A182JS18   A0A182V1D7   W8BBM6   A0A1B6EF92   A0A182VQN4   T1PH44   A0A0K8U8U2   A0A182QN41   A0A182N562   A0A2M4CZT0   A0A336LKS6   A0A182YK83   A0A182PIB7   A0A3B0J4I9   B4ME29   A0A182RHW6   B4J7V9   A0A341BJ04   A0A0D9RPU6   A0A2I3LM63   A0A3B0J0H1   A0A2I3MKI1   Q6PGP7   A0A2K5M519   A0A2R9AW40   F7DAC0   A0A2K5W236   G7MVA9   I2CUB2   A0A2K6R2B0   A0A2K5I6A7   H9EW22   B3MI76   A0A2K5Z6C4   A0A0P6J8B0   A0A2Y9PRZ3   A0A2Y9PYF0   A0A1S3J9U5   G5BU34   A0A2J8TDB7   A0A3Q2GV14   F6QDG2   A0A0P9ACT4   A0A1S3JAF0   A0A1W4UXL2  

PDB

4BUJ     E-value=3.69703e-12,     Score=178

KEGG

101743557    K12600 superkiller protein 3 | (RefSeq) tetratricopeptide repeat protein 37

PATHWAY

03018    RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0055087   GO:0006401   GO:0006396   GO:0000956   GO:0035327   GO:0005829   GO:0005654   GO:0005634   GO:0005737   GO:0043928   GO:0005515   GO:0008176   GO:0006468   GO:0005886   GO:0006171   GO:0035076   GO:0043401   GO:0008270   GO:0003700   GO:0043565  

PANTHER

PTHR15704  

Subcellular location

Cytoplasm  
Nucleus  

Length:

1275

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01915

Exp number, first 60 AAs:

1e-05

Total prob of N-in:

0.00004

outside

1  -  1275

 

 

Pi

244.553496

Theta

193.713764

Tajima's D

0.6899

CLR

0.00023

CSRT

0.569871506424679

Interpretation

Uncertain