SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05630
Pre Gene Modal
BGIBMGA006555
Annotation
PREDICTED:_Ca(2+)/calmodulin-responsive_adenylate_cyclase_[Bombyx_mori]
Location
Bomo_Chr10(-):6765568-6834998      View in EpiBrowser
Location in the cell
Nuclear   Reliability : 1.856 PlasmaMembrane   Reliability : 1.46
 

Sequence

CDS
ATGGTTGGCGTATTGAGTATCCACGCTGTGCTGTGCAGCGGATTGGCGTGGTGGTGCGGCCGGACTGACGGTGTGGCACCAGAGAGGCGGTTGCCGCGGGCATGCTGGCTGGCCCTGGCTGGCGGGGGTGCGGTACTAGCTGCCACGCTGCCCGCCTGGAGCCCGGGTGCTGCAGCCGAGGGCGCTGTGCATGTCGTCTGGGCTGTCTTCGCTGCCTATGCTCTGCTACCTGTTGGCGCTCCTGTCGCTGCCGCCTTTGGCATTGTCTTACCAACAGTCCATACCATCGCCGCTGCGCTTGTTGCTCATCGCTTTCCTTATCACGTCTGGCAGCAGATGCTGGGCAATGTGGTCGTGTTCGTTTGTGTGAATGTGGTTGGAGCTTTGATGCACTCGCTGATGGAAACCGCCCAGCGCAGAGCCTTCCTAGACACCAGGAACTGCATCGCGGCGAGACTCGACATGGAAGACGAAAACGAGAAATTGGAAAGGTTACTGTTATCCGTTCTCCCGCAACACGTCGCTATGGAGATGAAGAACGATATCATATCGCCGGTCGAGGGACAGTTCCACAAGATATACATACAGAAACACGAACAAGTCAGCATACTGTTTGCGGACATCGTCGGTTTTACTGTACTCGCTTCGCAGTGCAGCGCGCAGGAGCTGGTGCGGCTACTGAACGAACTGTTCGGAAGATTCGATCAATTGGCGAACGACAATCATTGCCTCCGCATCAAGATCCTGGGTGACTGTTACTACTGCGTGTCGGGATTGCCGGAGCCGCGCTCCGACCACGCTCGCTGCACCGTCGAGATGGGACTAGACATGATCGATGGCATCGCGTCAGTTGTGGAGGCTACCGACGTACAGCTAAACATGCGGGTGGGAATACACACGGGCCGAGTGTTGTGCGGAGTGCTCGGTCTTCGCAAGTGGCAGTACGATGTGTGGTCCAATGACGTCACTCTTGCAAACAATATGGAAGCTGGCGGCGAACCTGGTCGTGTACACATCACCCAAGCCACGTTGGAGTGCCTGGGAGGTGCGTACGAGGTAGAGCCGGGCCACGGAGCTAGTCGCAACGCGTACCTAAGGGACCACTCTGTTCAGACATACTTCATTATACCGCCGCCCAGGAGAAGAAAAATGTGTTTATCTTCGACGGCGGGACTGGGCACGGGCTCGCGTCGGAAACTATCCTTCAAGAACGTTTCCAACGTGGTCGTACAACTCCTGCACTCGATTAAGTTCAACGTGGATGTTCCGTTCTCGAATATGGCAGCGTCGCCTCAGGAACTCAAGGCCAATGCAGCCCGGAAGAATAAGGTAACGGAGAAATTTAAGCGGCCTCTGAAAAAGCGTCACTCGTCTGTCTACCACCAGCCCACCAACCGCGTCAACAAGTACCTAGCGCAAGCCATAGACGCCCGTTCCGTGCATCGCGAGAAGGCAACTCACGTGCATCTGCTAACGTTGTGCTTCAAACAAGCAGACAAAGAGGCTCAGTACCGCGCGTCAACGGACGGCGGCTGGGCCGGGTCGCTGGGTGCGGCTCTGGGCGCGCTGGTGGCGGCGGGCACGCTGCAGGCCGCCATCTTGCCGCGCACCACCATCTTGTTGCTGCTCTTCGTCACCGCTTTCGCGTGGTCGGCTGCCGTTCTCGCGTTGACTCTAGCCGCTCGACTGAGGCTCATACCTTGCGATGTATCCAGGCCGTTCGCTCTCAGGAACGCCATCACGACCTTCACTCTCGTGCTGGGCTATGCCGTGGGCCAAGTTAATGTGGTGACGTGCCGCAAAGTGGACGTGTGTCGGAACCTCACCGAGAACGTAACGATGGATGATATCAGTATGGCGAGTGACGACGTCGCGTCTCTGCTGTGGAGCAGCGCCGACCACCGCGCGTGTCCGGTGCCGCTGTACGTGACGCTGGGCTGCTGCCTCAGCATGCTGGCGGTCGCGGGCTTCCTCAGACTGCCGATACTGATCAAGGGCATCCTCCTCTACGTCATGACGGCCGGGTACATGGTAGTCATACTGGCCTACCATAAGGACTTGTTCGACTGCTACGATCTAATGACCGAACCGGGGCCAGTTGGGTCAGCGTACGTCGCCTGCGCCTGGACGCTGGCACTGGCACTGGCAGTGTTATTGCACGCGCGGCAGACGGAGTGGACGGCGCGACTCGACTTCTTGTGGCAAGTTCAAGCGCGCGATGAGAAAAGAGACATGGACGCTCTACAGGCATCAAACAGAAGAATACTGTTCAACCTCTTACCGGCGCACGTGGCCACTCACTTCTTGGATAATCAATTTAGAACAAATATGGACCTGTACCACCAGTCGTACCAGCGCGTCGGCGTCGTGTTCGCCTCCATCACCAACTACCACGAGTTCTACATGGAGCTCGACGGGAACAACCAGGGCATGGAGTGTCTGCGCTTGCTCAACGAAATCATAGCCGACTTCGATGAGCTTTTAGGTGAAGATCGCTTCAGTGCAATAGATAAAATAAAGACTGTCGGCTCAACGTACATGGCTGCCGTCGGTTTGATCCCGGACAAAAAAATGGCGGACGAAGTAAGCACGCGCAAGCACATGGCCACCCTGGTTGAATTCGTTTTTTCTATGAGGGACAAACTCAAAGACATCAACGACAACTCATACAATAACTTTATGCTCAGAGTCGGTATCAACGTCGGGCCCGTGGTGGCCGGTGTGATTGGCGCGAGGAAACCACAGTACGACATTTGGGGGAACACCGTCAATGTTGCCTCACGAATGGATTCCACCGGCCTGCCGAATCACACTCAAGTTACAGAAGAAGTGTATCACGTGTTGAAGGATATGCCGTACCAGTTTGTGTGCAGGGGGAAGGTCAAAGTTAAAGGGAAGGGCGAGATGACTACTTACTTCTTGACGGACCGAGCGCCAACGAACGGCACTGCGCAGAACCCGGCTAATCCTCCATCTACGAATCCCGCGACCGCCTACGGCGGCGTGGCCACTCCGCTAGCGATGCTGCAGAACTCGGCCAGGAGGGCGGCGGCGCAGCCATCGAGACTGCCGCCGGTGCGAGAGGCCTCGGTCGCAGGCGAGAACGAACCTCTATTGCCCACTAACAGCCAACAGATCAACGGTAATAATCACAAGGGCAGTAAAGGTCGCAGGAACAAAGACTCTATCCCTGAAGAAGCGCCACCGCCGCCTCCTCCCCATGGAATGTCAAACCCTAGATGGCCGCCGCCTCGAGCACTGGTGCCGCCCTGGCCCCGTCCGCAGGAGCCCCGGCCTCCAGTAGCGCACAAGAGACGGCCCCCGACGCGCCTGCCGCGGCCTCGCTCTAGTGAGAGCCTACCGTTAACGCGGAGCCCCCGGGTCCATTCGTCTGCGGACGAGTTAAGTTCTTTAACGCGATCTCCGAGTCTTAGTTCGTCAGACGAAAGCTATTCGCGAACAACTGACGCTTCTCCTTCGCCTCCCCGCATATCTCAATGGCTCCCCGCCTCACGGCCGAACCGGTCGAGTCCTAATCAGCCGTACGACTACCCGCCTTCAAGAGCGACGAAGCCTGTTTCGAATCACATCAACGAAATATATTCGAAGCATAAAATATCAAAAAAACCATCGTTAGACGACAAGTTTTTAGATGTAGATCATCAGAAAGAGGATGAAAAACTTCCAAGGACCATCATTAATCTATTACAAACTTCGGCGAAGCGTGATGGGTGCTGTCAAACGGACAAGAAGGAAGGCCGCATGGGACAACGAGCCAGCTCATTCTCCAGTTCGGGCAGCAGACCGAATAATTTCAAACATTTCAATCACGATTCGGTAGACGTGTACACAAAAAGGAGTCCATCCGACGTGGCGTGCGTGCCGCCTTTCGAAAGGGAAATACAAAGACTATTAGAGGATAAAAATCTCATCAAAAGCAATCCACCCAAACTCGAAAGGAAAGAACTCAAACTCGATCTGAGGAGCCAGAACCCGTCGCTGGATTCGGTTCGCAACAATAACAACAACAACAACAGCAGCCCGCTGCACGCGGTGGGGCTGGCGGCCATCGCTCAGCTGGCGCGGCAGGACGCCCCCCCTGCCGCCCCTGCCGGTGACTTCCCCGGCGTGCTGCCCACCGACGTCGTCGTCCAGCTGCCCTCACCCACGCACTCAAGGGAACAACGCTCGACCCCGCAGTTTGAAAGGAAAGCGGAGGCCCTGGCGATGAAAGAAAAACACGAGAAAGAAATTCAAGAAAGACTACAAAGCAGGGTGACCACTTCTAACTTGAGGGAAATGGGCCTCTACGGCGAAAGTCAGTCTGAATGGAGTTCGTCCTGTTCGGAGGGAGAAGGCGACGGAGACTGTGGACACCCCGAGAGCACCGGATATACCACAGACGACCCCGCCCTCGAAAACGTGTCGATGCTCAACGAGGCCGGCCTCACGGACGCCGAGGCGGCCCTCAGCGACGTGAACTCCTGCTACCTGGACCGCGACGACGACGTCTCCTCGCGGGCCTCCTCGCGCCTCCTCGACTCCGAGGCGCTCGTGTCCCTGGAGTCGCTGAGCGCTATATACGACTCCGACGAACCCGCCCACAGGTACTTGGCCAACATCCGTACCGTCAGCGAATCCATTACGAGGAACTTCGGGCAGCCGGCGCACGTCACCGACGCCGAAAGCGATGTTTAG
Protein
MVGVLSIHAVLCSGLAWWCGRTDGVAPERRLPRACWLALAGGGAVLAATLPAWSPGAAAEGAVHVVWAVFAAYALLPVGAPVAAAFGIVLPTVHTIAAALVAHRFPYHVWQQMLGNVVVFVCVNVVGALMHSLMETAQRRAFLDTRNCIAARLDMEDENEKLERLLLSVLPQHVAMEMKNDIISPVEGQFHKIYIQKHEQVSILFADIVGFTVLASQCSAQELVRLLNELFGRFDQLANDNHCLRIKILGDCYYCVSGLPEPRSDHARCTVEMGLDMIDGIASVVEATDVQLNMRVGIHTGRVLCGVLGLRKWQYDVWSNDVTLANNMEAGGEPGRVHITQATLECLGGAYEVEPGHGASRNAYLRDHSVQTYFIIPPPRRRKMCLSSTAGLGTGSRRKLSFKNVSNVVVQLLHSIKFNVDVPFSNMAASPQELKANAARKNKVTEKFKRPLKKRHSSVYHQPTNRVNKYLAQAIDARSVHREKATHVHLLTLCFKQADKEAQYRASTDGGWAGSLGAALGALVAAGTLQAAILPRTTILLLLFVTAFAWSAAVLALTLAARLRLIPCDVSRPFALRNAITTFTLVLGYAVGQVNVVTCRKVDVCRNLTENVTMDDISMASDDVASLLWSSADHRACPVPLYVTLGCCLSMLAVAGFLRLPILIKGILLYVMTAGYMVVILAYHKDLFDCYDLMTEPGPVGSAYVACAWTLALALAVLLHARQTEWTARLDFLWQVQARDEKRDMDALQASNRRILFNLLPAHVATHFLDNQFRTNMDLYHQSYQRVGVVFASITNYHEFYMELDGNNQGMECLRLLNEIIADFDELLGEDRFSAIDKIKTVGSTYMAAVGLIPDKKMADEVSTRKHMATLVEFVFSMRDKLKDINDNSYNNFMLRVGINVGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPNHTQVTEEVYHVLKDMPYQFVCRGKVKVKGKGEMTTYFLTDRAPTNGTAQNPANPPSTNPATAYGGVATPLAMLQNSARRAAAQPSRLPPVREASVAGENEPLLPTNSQQINGNNHKGSKGRRNKDSIPEEAPPPPPPHGMSNPRWPPPRALVPPWPRPQEPRPPVAHKRRPPTRLPRPRSSESLPLTRSPRVHSSADELSSLTRSPSLSSSDESYSRTTDASPSPPRISQWLPASRPNRSSPNQPYDYPPSRATKPVSNHINEIYSKHKISKKPSLDDKFLDVDHQKEDEKLPRTIINLLQTSAKRDGCCQTDKKEGRMGQRASSFSSSGSRPNNFKHFNHDSVDVYTKRSPSDVACVPPFEREIQRLLEDKNLIKSNPPKLERKELKLDLRSQNPSLDSVRNNNNNNNSSPLHAVGLAAIAQLARQDAPPAAPAGDFPGVLPTDVVVQLPSPTHSREQRSTPQFERKAEALAMKEKHEKEIQERLQSRVTTSNLREMGLYGESQSEWSSSCSEGEGDGDCGHPESTGYTTDDPALENVSMLNEAGLTDAEAALSDVNSCYLDRDDDVSSRASSRLLDSEALVSLESLSAIYDSDEPAHRYLANIRTVSESITRNFGQPAHVTDAESDV

Summary

Similarity
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Uniprot
A0A3S2PEE7   H9JAL0   A0A2H1VGW0   A0A194QRJ3   A0A212EN92   A0A194PKE1   + More
A0A0L7L3S1  
Pubmed
19121390    26354079    22118469    26227816   
EMBL
RSAL01000073    RVE48984.1    BABH01008761    BABH01008762    BABH01008763    ODYU01002505    + More
SOQ40089.1    KQ461198    KPJ06156.1    AGBW02013690    OWR42962.1    KQ459606    KPI91560.1    JTDY01003150    KOB70065.1   
Proteomes
UP000283053    UP000005204    UP000053240    UP000007151    UP000053268    UP000037510    + More
PRIDE
H9JAL0   
Pfam
PF06327   DUF1053        + More
PF16214   AC_N
PF00211   Guanylate_cyc
Interpro
IPR009398   Adcy_conserved_dom        + More
IPR029787   Nucleotide_cyclase       
IPR032628   AC_N       
IPR001054   A/G_cyclase       
IPR018297   A/G_cyclase_CS       
SUPFAM
SSF55073   SSF55073       
Gene 3D
3.30.70.1230    
ProteinModelPortal
A0A3S2PEE7   H9JAL0   A0A2H1VGW0   A0A194QRJ3   A0A212EN92   A0A194PKE1   + More
A0A0L7L3S1  
PDB
3MAA     E-value=1.07753e-87,     Score=830

Ontologies

KEGG
101741402    K08041 adenylate cyclase 1 [EC:4.6.1.1] | (RefSeq) Ca(2+)/calmodulin-responsive adenylate cyclase
PATHWAY
00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)
GO
GO:0016021   GO:0000166   GO:0016829   GO:0004016   GO:0005886   GO:0006171   GO:0035556   GO:0009190   GO:0016849   GO:0035076   GO:0043401   GO:0008270   GO:0003700   GO:0043565  

Topology

Length:
1565
Number of predicted TMHs:
11
Exp number of AAs in TMHs:
231.05074
Exp number, first 60 AAs:
32.67422
Total prob of N-in:
0.40767
POSSIBLE N-term signal
sequence
inside
1  -  1
TMhelix
2  -  19
outside
20  -  33
TMhelix
34  -  53
inside
54  -  65
TMhelix
66  -  88
outside
89  -  107
TMhelix
108  -  130
inside
131  -  511
TMhelix
512  -  534
outside
535  -  538
TMhelix
539  -  561
inside
562  -  573
TMhelix
574  -  596
outside
597  -  637
TMhelix
638  -  660
inside
661  -  666
TMhelix
667  -  684
outside
685  -  698
TMhelix
699  -  721
inside
722  -  888
TMhelix
889  -  911
outside
912  -  1565
 
 

Population Genetic Test Statistics

Pi
238.898634
Theta
177.27726
Tajima's D
1.022098
CLR
0.239777
CSRT
0.667116644167792
Interpretation
Uncertain
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