Gene

KWMTBOMO05610  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006771

Annotation

PREDICTED:_peptidyl-prolyl_cis-trans_isomerase_H_[Amyelois_transitella]

Location

Bomo_Chr10(+):6300165-6301034      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.168

CDS

ATGCCTACTTGGAACCAAATACAGTCACAACTTAGGAATCCTAACAATCCAGTAGTGTTTTTCGACATTACTGTAGGAACAACGGAAATAGGTCGTATGATATTCGAGTTATTCGCCGACGTAGTACCAAAAACTAGTGAGAACTTCAGAGAATTTTGTACCGGTGAATACAGGCGGGATGGTGTGCCCTTAGGTTACAAAGGAGCTACTTTTCACAGAGTAATAAAAGATTTTATGATTCAGGGTGGCGATTTCGTAAATGGAGACGGTACAGGCGTTATGAGCATATATGGTGGAAGCACTTTTGCAGATGAAAACTTTGGTTTGAAACATGACTCTCCAGGGTTATTGTCCATGGCAAATAGTGGTAAAGACACGAATGGCTGTCAGTTCTTTATCACATGTGCAAAATGTAATTTCTTAGACAATAAGCATGTAGTATTTGGTAGAGTTATAGATGGATTACTTGTCATGAGGAAAATAGAAAATGTACCAACAGGACCAAATAATAAACCTAAAATACCAGTAACAATATCTCAATGTGGACAAATGTAA

Protein

MPTWNQIQSQLRNPNNPVVFFDITVGTTEIGRMIFELFADVVPKTSENFREFCTGEYRRDGVPLGYKGATFHRVIKDFMIQGGDFVNGDGTGVMSIYGGSTFADENFGLKHDSPGLLSMANSGKDTNGCQFFITCAKCNFLDNKHVVFGRVIDGLLVMRKIENVPTGPNNKPKIPVTISQCGQM

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the cyclophilin-type PPIase family.

Uniprot

H9JB76   A0A1C9EGN3   A0A194QRL2   I4DL19   A0A3S2LA18   A0A2A4JQT4   + More
A0A2H1WPA7   S4P9W6   A0A194PEY5   A0A212EQ27   A0A2J7R720   A0A067RJN0   A0A2P8XDI1   J3JXH2   A0A0P4VKX1   T1HU05   E0VAV7   A0A154PMY5   A0A2A3ERC5   A0A088AVK4   A0A1B6CKV4   E2BCJ0   A0A224XZ75   A0A023F5S1   A0A195CS39   A0A195EMS6   F4WX51   A0A195BXF2   A0A0J7NHL9   A0A195FAB1   A0A158NCJ1   E2ALW5   A0A026WXB7   A0A1B6MGG6   A0A1S3D1M1   V5GA76   A0A1Y1KL11   A0A0M8ZPS7   E9IM86   A0A1I8PNJ5   A0A0L7RJ43   A0A0L0C2X8   A0A1L8DUD4   W8AQX3   A0A1B6IHD8   A0A1B0EVI6   A0A1I8MCY6   A0A0K8TPJ8   A0A1A9WK32   A0A0T6B1T4   A0A232EPK8   K7J4J9   D7ELY5   A0A182GLV9   A0A182PQK1   T1GUZ9   Q17FA3   A0A0C9RIB8   A0A0K8U935   A0A034WRF9   A0A182XYR2   A0A182T435   A0A1W4XHZ7   A0A1Q3G288   A0A182JR01   A0A1A9VX70   A0A182NI06   A0A0A9WRJ5   A0A182QZY6   A0A182MHF7   B4P0Z5   T1J4C1   A0A182VGL9   B0WT36   B3MIQ3   A0A0K8T1P9   A0A182R7C7   A0A182WJC9   A0A2P6KK03   A0A2S2QPB4   B4HPX0   B4QDB1   Q4V5H1   A0A2L2YJU8   A0A1W4VF67   B3NB40   A0A182J5R4   A0A0V0GCW5   W5JSA2   B4J6I9   A0A182TX78   A0A182X3W3   A0A182KR65   Q7QJB3   A0A182I359   A0A2M3ZJY4   A0A2M4AYJ0   A0A182FGV4   A0A2M4C0T9   B4LK03  

EC Number

5.2.1.8

Pubmed

19121390    26354079    22651552    23622113    22118469    24845553    + More
29403074    22516182    23537049    27129103    20566863    20798317    25474469    21719571    21347285    24508170    28004739    21282665    26108605    24495485    25315136    26369729    28648823    20075255    18362917    19820115    26483478    17510324    25348373    25244985    25401762    26823975    17994087    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26561354    20920257    23761445    20966253    12364791    14747013    17210077   

EMBL

BABH01008721    KX778610    AON96654.1    KQ461198    KPJ06176.1    AK401987    + More
BAM18609.1    RSAL01000073    RVE49007.1    NWSH01000751    PCG74397.1    ODYU01009998    SOQ54782.1    GAIX01003529    JAA89031.1    KQ459606    KPI91583.1    AGBW02013342    OWR43567.1    NEVH01006738    PNF36637.1    KK852470    KDR23198.1    PYGN01002721    PSN30053.1    APGK01056100    APGK01056101    APGK01056102    BT127941    KB741274    KB632130    AEE62903.1    ENN71339.1    ERL88980.1    GDKW01000840    JAI55755.1    ACPB03014264    DS235016    EEB10513.1    KQ434998    KZC13245.1    KZ288198    PBC33679.1    GEDC01023285    JAS14013.1    GL447292    EFN86591.1    GFTR01003065    JAW13361.1    GBBI01002187    JAC16525.1    KQ977408    KYN02929.1    KQ978691    KYN29189.1    GL888417    EGI61294.1    KQ976396    KYM92975.1    LBMM01004903    KMQ92005.1    KQ981727    KYN36984.1    ADTU01011940    GL440682    EFN65557.1    KK107088    EZA59789.1    GEBQ01004929    JAT35048.1    GALX01001451    JAB67015.1    GEZM01082676    JAV61298.1    KQ435922    KOX68437.1    GL764129    EFZ18346.1    KQ414582    KOC70870.1    JRES01000975    KNC26592.1    GFDF01004040    JAV10044.1    GAMC01019630    GAMC01019627    GAMC01019621    GAMC01019617    GAMC01019611    JAB86928.1    GECU01021377    JAS86329.1    AJWK01020251    AJWK01020252    GDAI01001788    JAI15815.1    LJIG01016188    KRT81350.1    NNAY01002921    OXU20295.1    AAZX01016829    DS497945    EFA12464.1    JXUM01073168    KQ562759    KXJ75181.1    CAQQ02191165    CH477272    EAT45244.1    GBYB01012962    JAG82729.1    GDHF01029211    GDHF01019106    JAI23103.1    JAI33208.1    GAKP01000786    GAKP01000785    GAKP01000784    JAC58166.1    GFDL01001186    JAV33859.1    GBHO01032542    GDHC01003737    JAG11062.1    JAQ14892.1    AXCN02000386    AXCM01001984    CM000157    EDW89069.1    JH431842    DS232080    EDS34179.1    CH902619    EDV38129.1    GBRD01006711    JAG59110.1    MWRG01010256    PRD26660.1    GGMS01010413    MBY79616.1    CH480816    EDW46639.1    CM000362    CM002911    EDX05898.1    KMY91766.1    AE013599    BT022685    AAM70809.1    AAY55101.1    IAAA01033394    IAAA01033395    LAA08386.1    CH954177    EDV59805.1    GECL01000286    JAP05838.1    ADMH02000243    ETN67262.1    CH916367    EDW01990.1    AAAB01008807    EAA04625.2    APCN01000199    GGFM01008007    MBW28758.1    GGFK01012504    MBW45825.1    GGFJ01009776    MBW58917.1    CH940648    EDW61657.1   

Proteomes

UP000005204    UP000053240    UP000283053    UP000218220    UP000053268    UP000007151    + More
UP000235965    UP000027135    UP000245037    UP000019118    UP000030742    UP000015103    UP000009046    UP000076502    UP000242457    UP000005203    UP000008237    UP000078542    UP000078492    UP000007755    UP000078540    UP000036403    UP000078541    UP000005205    UP000000311    UP000053097    UP000079169    UP000053105    UP000095300    UP000053825    UP000037069    UP000092461    UP000095301    UP000091820    UP000215335    UP000002358    UP000007266    UP000069940    UP000249989    UP000075885    UP000015102    UP000008820    UP000076408    UP000075901    UP000192223    UP000075881    UP000078200    UP000075884    UP000075886    UP000075883    UP000002282    UP000075903    UP000002320    UP000007801    UP000075900    UP000075920    UP000001292    UP000000304    UP000000803    UP000192221    UP000008711    UP000075880    UP000000673    UP000001070    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000069272    UP000008792   

PRIDE

H9JB76    Q4V5H1   

Pfam

PF00160   Pro_isomerase

Interpro

IPR020892   Cyclophilin-type_PPIase_CS        + More
IPR029000   Cyclophilin-like_dom_sf       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR024936   Cyclophilin-type_PPIase       

SUPFAM

SSF50891   SSF50891       

Gene 3D

2.40.100.10    

ProteinModelPortal

H9JB76   A0A1C9EGN3   A0A194QRL2   I4DL19   A0A3S2LA18   A0A2A4JQT4   + More
A0A2H1WPA7   S4P9W6   A0A194PEY5   A0A212EQ27   A0A2J7R720   A0A067RJN0   A0A2P8XDI1   J3JXH2   A0A0P4VKX1   T1HU05   E0VAV7   A0A154PMY5   A0A2A3ERC5   A0A088AVK4   A0A1B6CKV4   E2BCJ0   A0A224XZ75   A0A023F5S1   A0A195CS39   A0A195EMS6   F4WX51   A0A195BXF2   A0A0J7NHL9   A0A195FAB1   A0A158NCJ1   E2ALW5   A0A026WXB7   A0A1B6MGG6   A0A1S3D1M1   V5GA76   A0A1Y1KL11   A0A0M8ZPS7   E9IM86   A0A1I8PNJ5   A0A0L7RJ43   A0A0L0C2X8   A0A1L8DUD4   W8AQX3   A0A1B6IHD8   A0A1B0EVI6   A0A1I8MCY6   A0A0K8TPJ8   A0A1A9WK32   A0A0T6B1T4   A0A232EPK8   K7J4J9   D7ELY5   A0A182GLV9   A0A182PQK1   T1GUZ9   Q17FA3   A0A0C9RIB8   A0A0K8U935   A0A034WRF9   A0A182XYR2   A0A182T435   A0A1W4XHZ7   A0A1Q3G288   A0A182JR01   A0A1A9VX70   A0A182NI06   A0A0A9WRJ5   A0A182QZY6   A0A182MHF7   B4P0Z5   T1J4C1   A0A182VGL9   B0WT36   B3MIQ3   A0A0K8T1P9   A0A182R7C7   A0A182WJC9   A0A2P6KK03   A0A2S2QPB4   B4HPX0   B4QDB1   Q4V5H1   A0A2L2YJU8   A0A1W4VF67   B3NB40   A0A182J5R4   A0A0V0GCW5   W5JSA2   B4J6I9   A0A182TX78   A0A182X3W3   A0A182KR65   Q7QJB3   A0A182I359   A0A2M3ZJY4   A0A2M4AYJ0   A0A182FGV4   A0A2M4C0T9   B4LK03  

PDB

6AHD     E-value=2.62725e-79,     Score=747

KEGG

101741170    K09567 peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8] | (RefSeq) peptidyl-prolyl cis-trans

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0003755   GO:0006457   GO:0001525   GO:0016018   GO:0042026   GO:0043021   GO:0045070   GO:0051082   GO:0071011   GO:0000398   GO:0000413   GO:0005634   GO:0006355   GO:0035076   GO:0043401   GO:0008270   GO:0003700   GO:0043565  

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13227

Exp number, first 60 AAs:

0.1189

Total prob of N-in:

0.22369

outside

1  -  184

 

 

Pi

285.993701

Theta

210.545423

Tajima's D

1.137201

CLR

0

CSRT

0.690815459227039

Interpretation

Uncertain