SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05607
Pre Gene Modal
BGIBMGA006569
Annotation
PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Bombyx_mori]
Full name
Fatty acyl-CoA reductase      
Location in the cell
PlasmaMembrane   Reliability : 2.057
 

Sequence

CDS
ATGACGTCACAAATAAACGAATGGTATAAAGGCCGGAAAGTCCTTATCACCGGTTCCTCCGGGCTGATGGGCAAGGTCTTAATAGAGAAATTACTGTATAGCGTTCCGGATATAGGATGCGTGTACGCGCTGGTGCGGTCCAAGCGAGGAAAGAGCCCGGAATCACGCATCGAAGACATGTGGAAATTGCCTCTTTTTACGAGAATAAGAGAAGAAAAGCCTCACGTGATGAAGAAGCTTGTAGCCGTCCCTGGCGACATAATCTGCGACAAACTAGGCATCGAAAAAACTAAACTAGAACAAATTTATAATGAGGTTTCGGTAGTTTTCCATTTCGCTGCAAGCTTACGTTTAGAAGCGCCATTGAAGGAAGGCTTGGAAATGAACACAAAAGGCACGATGCGTGTTTTGGAATTATCCAAGAACATAAAAAATTTGGTCGCTTTTGTACATCTGTCGACGGCTTTCTGTTATCCAGATTATGAGCGATTGGCCGAAAAGGTCCACGATCCCCCTACTGATCCCGAAAACGTACTTCAAGCGGCGAGTTGGCTCACCGAACAGCAGTTAAACATTCTCGCTCCTTCAATATACAAGAAGCACCCCAACTCTTACACGTATTCCAAAAGGCTGGCTGAAGCTCTTGTGAAAGAGAGCTACCCTCAACTACCGGCAGTTGTAGTTAGACCTAGTATAGTGACACCCGCATACAAAGAGCCCATAGCAGGTTGGGTTGATAATCTAAACGGCCCCATTGGTTTGATGGTAGGCGCCGGGAAGGGCGTCATCCGCTCCATGCACTGCTACGGTCATTACCACGCCGAGGTCATACCGATAGACATCGCTATTAACGCCATTATAGTTATAAGCTACAAGATTGGAAATCAGTCTGAAAGACCTCCAGAAATACCGACATTCAACCTCACTACAGGAGACGACAGGAACACAACATGGAAGGAAGTTCTGGATATCGGTAAAGCGACCGTTCGAAAGTATCCCTTCGAAGGTCCCCTCTGGTATCCGAACGGCAACATCAGACATAATAAGTTCATACATGACTTGTGTGTGTTCTTCTACCATCTAGTTCCGGCGTATTTTATTGATTTTCTGATGTTTTTGTTCATGCAGAAACGATTTATGGTTCGGATTCAAAATAGGATTTCAGTAGGTCTAGAGGTGCTACAATATTTCACGACGCGTGAATGGTGGTTCGATACAGATAATTTCAAAGCTTTAGCTACAATGTTGAATCCTGTTGATAAGGAAGTTTTTCCTATGGACCTAAGCGTCATTGAAGACGAGCCTTACATAGAGAGCTGTATGATCGGGGGCAAGCTGTATTGCATGAAAGAGAAGCTTGAGAATTTGCCTAAAGCAAGACTCCAGAATAATATTCTCTACGTCTTGGATAAAATAACAACAGTCTTTTTCTACTTGATCCTGCTGTACTGGGTAGTACTGTATTGCGCACCAGTCCGCGAAGTATTATCTTATGGCGGTCCATTTGTTCGATACCTACCTTTGGTGGGTAAAGCGGTTTTTAAAAATGATCTTTAA
Protein
MTSQINEWYKGRKVLITGSSGLMGKVLIEKLLYSVPDIGCVYALVRSKRGKSPESRIEDMWKLPLFTRIREEKPHVMKKLVAVPGDIICDKLGIEKTKLEQIYNEVSVVFHFAASLRLEAPLKEGLEMNTKGTMRVLELSKNIKNLVAFVHLSTAFCYPDYERLAEKVHDPPTDPENVLQAASWLTEQQLNILAPSIYKKHPNSYTYSKRLAEALVKESYPQLPAVVVRPSIVTPAYKEPIAGWVDNLNGPIGLMVGAGKGVIRSMHCYGHYHAEVIPIDIAINAIIVISYKIGNQSERPPEIPTFNLTTGDDRNTTWKEVLDIGKATVRKYPFEGPLWYPNGNIRHNKFIHDLCVFFYHLVPAYFIDFLMFLFMQKRFMVRIQNRISVGLEVLQYFTTREWWFDTDNFKALATMLNPVDKEVFPMDLSVIEDEPYIESCMIGGKLYCMKEKLENLPKARLQNNILYVLDKITTVFFYLILLYWVVLYCAPVREVLSYGGPFVRYLPLVGKAVFKNDL

Summary

Description
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Catalytic Activity
a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)
Similarity
Belongs to the fatty acyl-CoA reductase family.
Feature
chain  Fatty acyl-CoA reductase
EC Number
1.2.1.84
EMBL
BABH01008715    BABH01008716    KU755486    ARD71196.1    MF687593    ATJ44519.1    + More
MF687538    ATJ44464.1    NWSH01000351    PCG77133.1    ODYU01001961    SOQ38879.1    JX989160    AGR49319.1    KJ622063    AID66651.1    KX778610    AON96651.1    KP237928    AKD01781.1    AGBW02013342    OWR43572.1    AK402400    BAM19022.1    KQ461198    KPJ06182.1    KQ459606    KPI91588.1    RSAL01000039    RVE51027.1    HM536634    ADI87410.1    KQ461108    KPJ09220.1    KQ414868    KOC59957.1    KT261701    ALJ30241.1    ODYU01001651    SOQ38173.1    GBYB01007475    JAG77242.1    KZ149961    PZC76330.1    KQ977444    KYN02613.1    KQ982080    KYQ60351.1    KQ459594    KPI96166.1    KP237917    AKD01770.1    MF687546    ATJ44472.1    KP237930    AKD01783.1    KQ981490    KYN41164.1    KQ435728    KOX77819.1    KU755482    ARD71192.1    NWSH01000478    PCG76112.1    GANO01003516    JAB56355.1    GL762454    EFZ21418.1    APCN01003255    ADMH02001477    ETN62440.1    CH478247    EAT33424.1    KQ978625    KYN29624.1    AXCM01000910    GL888387    EGI61763.1    AAAB01008888    EAA08761.5    AJWK01025254    AJWK01025255    AJWK01025256    GBYB01007474    JAG77241.1    AXCN02000243    GFDL01000089    JAV34956.1    GFDF01002656    JAV11428.1    KK107109    QOIP01000008    EZA59252.1    RLU19596.1    ATLV01026503    ATLV01026504    KE525415    KFB53143.1    KK852458    KDR23567.1    GEDC01030337    JAS06961.1    GL444010    EFN61377.1    KQ976401    KYM92422.1    GECU01013104    JAS94602.1    AGBW02007730    OWR54654.1    GEZM01074076    JAV64682.1    GECZ01020981    JAS48788.1    KB632169    ERL89445.1    GAKP01009042    JAC49910.1    APGK01049539    KB741156    ENN73525.1    CH902619    KPU76653.1    GAMC01010608    JAB95947.1    DS235862    EEB19202.1    EDV37236.2    CH933808    EDW09264.2    KZ288219    PBC32341.1    CM000158    KRK00613.1    GDHF01001846    JAI50468.1    GDHF01026452    JAI25862.1    CH954179    KQS63160.1    CH916367    EDW02538.1    UFQS01000822    UFQT01000822    SSX07044.1    SSX27387.1    KQ971321    EEZ99525.1    EDW92628.2    KQS63158.1    CM002911    KMY96476.1    GEDC01009624    JAS27674.1    CM000071    KRT01617.1    KMY96477.1    GBXI01004852    JAD09440.1    AE013599    BT133449    AAM70799.1    AFH89822.1    AAF47295.2   
Pfam
PF03015   Sterile        + More
PF07993   NAD_binding_4
Interpro
IPR013120   Male_sterile_NAD-bd        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR033640   FAR_C       
IPR026055   FAR       
SUPFAM
SSF51735   SSF51735       
PDB
4W4T     E-value=1.61539e-08,     Score=143

Ontologies

Topology

Length:
518
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
44.76507
Exp number, first 60 AAs:
0.11089
Total prob of N-in:
0.12497
outside
1  -  355
TMhelix
356  -  375
inside
376  -  464
TMhelix
465  -  487
outside
488  -  518
 
 

Population Genetic Test Statistics

Pi
227.077464
Theta
162.077106
Tajima's D
1.343033
CLR
0.003158
CSRT
0.750462476876156
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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