Gene

KWMTBOMO05607

Pre Gene Modal

BGIBMGA006569

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Bombyx_mori]

Location

Bomo_Chr10(-):6190122-6200634      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 2.057

CDS

ATGACGTCACAAATAAACGAATGGTATAAAGGCCGGAAAGTCCTTATCACCGGTTCCTCCGGGCTGATGGGCAAGGTCTTAATAGAGAAATTACTGTATAGCGTTCCGGATATAGGATGCGTGTACGCGCTGGTGCGGTCCAAGCGAGGAAAGAGCCCGGAATCACGCATCGAAGACATGTGGAAATTGCCTCTTTTTACGAGAATAAGAGAAGAAAAGCCTCACGTGATGAAGAAGCTTGTAGCCGTCCCTGGCGACATAATCTGCGACAAACTAGGCATCGAAAAAACTAAACTAGAACAAATTTATAATGAGGTTTCGGTAGTTTTCCATTTCGCTGCAAGCTTACGTTTAGAAGCGCCATTGAAGGAAGGCTTGGAAATGAACACAAAAGGCACGATGCGTGTTTTGGAATTATCCAAGAACATAAAAAATTTGGTCGCTTTTGTACATCTGTCGACGGCTTTCTGTTATCCAGATTATGAGCGATTGGCCGAAAAGGTCCACGATCCCCCTACTGATCCCGAAAACGTACTTCAAGCGGCGAGTTGGCTCACCGAACAGCAGTTAAACATTCTCGCTCCTTCAATATACAAGAAGCACCCCAACTCTTACACGTATTCCAAAAGGCTGGCTGAAGCTCTTGTGAAAGAGAGCTACCCTCAACTACCGGCAGTTGTAGTTAGACCTAGTATAGTGACACCCGCATACAAAGAGCCCATAGCAGGTTGGGTTGATAATCTAAACGGCCCCATTGGTTTGATGGTAGGCGCCGGGAAGGGCGTCATCCGCTCCATGCACTGCTACGGTCATTACCACGCCGAGGTCATACCGATAGACATCGCTATTAACGCCATTATAGTTATAAGCTACAAGATTGGAAATCAGTCTGAAAGACCTCCAGAAATACCGACATTCAACCTCACTACAGGAGACGACAGGAACACAACATGGAAGGAAGTTCTGGATATCGGTAAAGCGACCGTTCGAAAGTATCCCTTCGAAGGTCCCCTCTGGTATCCGAACGGCAACATCAGACATAATAAGTTCATACATGACTTGTGTGTGTTCTTCTACCATCTAGTTCCGGCGTATTTTATTGATTTTCTGATGTTTTTGTTCATGCAGAAACGATTTATGGTTCGGATTCAAAATAGGATTTCAGTAGGTCTAGAGGTGCTACAATATTTCACGACGCGTGAATGGTGGTTCGATACAGATAATTTCAAAGCTTTAGCTACAATGTTGAATCCTGTTGATAAGGAAGTTTTTCCTATGGACCTAAGCGTCATTGAAGACGAGCCTTACATAGAGAGCTGTATGATCGGGGGCAAGCTGTATTGCATGAAAGAGAAGCTTGAGAATTTGCCTAAAGCAAGACTCCAGAATAATATTCTCTACGTCTTGGATAAAATAACAACAGTCTTTTTCTACTTGATCCTGCTGTACTGGGTAGTACTGTATTGCGCACCAGTCCGCGAAGTATTATCTTATGGCGGTCCATTTGTTCGATACCTACCTTTGGTGGGTAAAGCGGTTTTTAAAAATGATCTTTAA

Protein

MTSQINEWYKGRKVLITGSSGLMGKVLIEKLLYSVPDIGCVYALVRSKRGKSPESRIEDMWKLPLFTRIREEKPHVMKKLVAVPGDIICDKLGIEKTKLEQIYNEVSVVFHFAASLRLEAPLKEGLEMNTKGTMRVLELSKNIKNLVAFVHLSTAFCYPDYERLAEKVHDPPTDPENVLQAASWLTEQQLNILAPSIYKKHPNSYTYSKRLAEALVKESYPQLPAVVVRPSIVTPAYKEPIAGWVDNLNGPIGLMVGAGKGVIRSMHCYGHYHAEVIPIDIAINAIIVISYKIGNQSERPPEIPTFNLTTGDDRNTTWKEVLDIGKATVRKYPFEGPLWYPNGNIRHNKFIHDLCVFFYHLVPAYFIDFLMFLFMQKRFMVRIQNRISVGLEVLQYFTTREWWFDTDNFKALATMLNPVDKEVFPMDLSVIEDEPYIESCMIGGKLYCMKEKLENLPKARLQNNILYVLDKITTVFFYLILLYWVVLYCAPVREVLSYGGPFVRYLPLVGKAVFKNDL

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Feature

chain  Fatty acyl-CoA reductase

Uniprot

H9JAM4   A0A1V0M881   A0A291P0Y2   A0A291P0Q9   A0A2A4K043   A0A2H1VDF8   + More
U5KG45   A0A068FMK7   A0A1C9EGN8   A0A0F6Q2P8   A0A212EPZ8   I4DM82   A0A194QKX4   A0A194PEZ0   A0A088APG8   A0A3S2NWX2   D9MX50   A0A194QW79   A0A0L7QMT0   A0A0P0DZ32   A0A2H1VBF1   A0A0C9RGI8   A0A2W1BU73   A0A195CPE7   A0A151XJ37   A0A194PRU4   A0A0F6Q2Z9   A0A291P0P8   A0A0F6Q4N3   A0A195FMJ1   A0A0M9A857   A0A1V0M879   A0A2A4JXJ6   A0A182VXI1   U5EPY7   E9ID65   A0A1S4G1B4   A0A182REU5   A0A182V6X2   A0A182I9C8   W5JHR7   A0A182JIX2   Q16GQ4   A0A195EP06   A0A182WVP9   A0A182LXW7   F4WVE2   Q7QAN3   A0A1B0CRT6   A0A0C9QUP1   A0A182KXM4   A0A182FRU7   A0A182QQN9   A0A182NFQ6   A0A1Q3G5B4   A0A182K6D3   A0A1W4XSR6   A0A1W4XHK8   A0A182P917   A0A1L8DYA8   A0A026WTB2   A0A182YI99   A0A084WSE9   A0A067RIF0   A0A1B6C0C4   E2AYW1   A0A195BV13   A0A182SVN7   A0A1B6J616   A0A212FLN3   A0A1Y1KTF8   A0A1B6FF15   A0A1A9UZB6   U4UHU2   A0A034W6Z8   N6TW75   A0A0P8ZQ48   W8BBB7   E0W0P6   B3MC49   B4KQR5   A0A2A3EMS1   A0A0R1DU59   A0A0K8WH42   A0A0K8UGQ7   A0A0Q5W393   B4J9N1   A0A336KQE3   D6WD88   B4PBX4   A0A0Q5VPH3   A0A0J9RKV0   A0A1B6DPR8   A0A0R3NKW5   A0A0J9RL31   A0A0A1XER0   Q8MMC6   Q0E8W1  

EC Number

1.2.1.84

Pubmed

19121390    28349297    28986331    24053512    26385554    22118469    + More
22651552    26354079    20542116    26445454    28756777    21282665    20920257    23761445    17510324    21719571    12364791    14747013    17210077    20966253    24508170    30249741    25244985    24438588    24845553    20798317    28004739    23537049    25348373    17994087    24495485    20566863    17550304    18362917    19820115    22936249    15632085    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

BABH01008715    BABH01008716    KU755486    ARD71196.1    MF687593    ATJ44519.1    + More
MF687538    ATJ44464.1    NWSH01000351    PCG77133.1    ODYU01001961    SOQ38879.1    JX989160    AGR49319.1    KJ622063    AID66651.1    KX778610    AON96651.1    KP237928    AKD01781.1    AGBW02013342    OWR43572.1    AK402400    BAM19022.1    KQ461198    KPJ06182.1    KQ459606    KPI91588.1    RSAL01000039    RVE51027.1    HM536634    ADI87410.1    KQ461108    KPJ09220.1    KQ414868    KOC59957.1    KT261701    ALJ30241.1    ODYU01001651    SOQ38173.1    GBYB01007475    JAG77242.1    KZ149961    PZC76330.1    KQ977444    KYN02613.1    KQ982080    KYQ60351.1    KQ459594    KPI96166.1    KP237917    AKD01770.1    MF687546    ATJ44472.1    KP237930    AKD01783.1    KQ981490    KYN41164.1    KQ435728    KOX77819.1    KU755482    ARD71192.1    NWSH01000478    PCG76112.1    GANO01003516    JAB56355.1    GL762454    EFZ21418.1    APCN01003255    ADMH02001477    ETN62440.1    CH478247    EAT33424.1    KQ978625    KYN29624.1    AXCM01000910    GL888387    EGI61763.1    AAAB01008888    EAA08761.5    AJWK01025254    AJWK01025255    AJWK01025256    GBYB01007474    JAG77241.1    AXCN02000243    GFDL01000089    JAV34956.1    GFDF01002656    JAV11428.1    KK107109    QOIP01000008    EZA59252.1    RLU19596.1    ATLV01026503    ATLV01026504    KE525415    KFB53143.1    KK852458    KDR23567.1    GEDC01030337    JAS06961.1    GL444010    EFN61377.1    KQ976401    KYM92422.1    GECU01013104    JAS94602.1    AGBW02007730    OWR54654.1    GEZM01074076    JAV64682.1    GECZ01020981    JAS48788.1    KB632169    ERL89445.1    GAKP01009042    JAC49910.1    APGK01049539    KB741156    ENN73525.1    CH902619    KPU76653.1    GAMC01010608    JAB95947.1    DS235862    EEB19202.1    EDV37236.2    CH933808    EDW09264.2    KZ288219    PBC32341.1    CM000158    KRK00613.1    GDHF01001846    JAI50468.1    GDHF01026452    JAI25862.1    CH954179    KQS63160.1    CH916367    EDW02538.1    UFQS01000822    UFQT01000822    SSX07044.1    SSX27387.1    KQ971321    EEZ99525.1    EDW92628.2    KQS63158.1    CM002911    KMY96476.1    GEDC01009624    JAS27674.1    CM000071    KRT01617.1    KMY96477.1    GBXI01004852    JAD09440.1    AE013599    BT133449    AAM70799.1    AFH89822.1    AAF47295.2   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000005203    + More
UP000283053    UP000053825    UP000078542    UP000075809    UP000078541    UP000053105    UP000075920    UP000075900    UP000075903    UP000075840    UP000000673    UP000075880    UP000008820    UP000078492    UP000076407    UP000075883    UP000007755    UP000007062    UP000092461    UP000075882    UP000069272    UP000075886    UP000075884    UP000075881    UP000192223    UP000075885    UP000053097    UP000279307    UP000076408    UP000030765    UP000027135    UP000000311    UP000078540    UP000075901    UP000078200    UP000030742    UP000019118    UP000007801    UP000009046    UP000009192    UP000242457    UP000002282    UP000008711    UP000001070    UP000007266    UP000001819    UP000000803   

PRIDE

H9JAM4    Q8MMC6    Q0E8W1   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4

Interpro

IPR013120   Male_sterile_NAD-bd        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR033640   FAR_C       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

H9JAM4   A0A1V0M881   A0A291P0Y2   A0A291P0Q9   A0A2A4K043   A0A2H1VDF8   + More
U5KG45   A0A068FMK7   A0A1C9EGN8   A0A0F6Q2P8   A0A212EPZ8   I4DM82   A0A194QKX4   A0A194PEZ0   A0A088APG8   A0A3S2NWX2   D9MX50   A0A194QW79   A0A0L7QMT0   A0A0P0DZ32   A0A2H1VBF1   A0A0C9RGI8   A0A2W1BU73   A0A195CPE7   A0A151XJ37   A0A194PRU4   A0A0F6Q2Z9   A0A291P0P8   A0A0F6Q4N3   A0A195FMJ1   A0A0M9A857   A0A1V0M879   A0A2A4JXJ6   A0A182VXI1   U5EPY7   E9ID65   A0A1S4G1B4   A0A182REU5   A0A182V6X2   A0A182I9C8   W5JHR7   A0A182JIX2   Q16GQ4   A0A195EP06   A0A182WVP9   A0A182LXW7   F4WVE2   Q7QAN3   A0A1B0CRT6   A0A0C9QUP1   A0A182KXM4   A0A182FRU7   A0A182QQN9   A0A182NFQ6   A0A1Q3G5B4   A0A182K6D3   A0A1W4XSR6   A0A1W4XHK8   A0A182P917   A0A1L8DYA8   A0A026WTB2   A0A182YI99   A0A084WSE9   A0A067RIF0   A0A1B6C0C4   E2AYW1   A0A195BV13   A0A182SVN7   A0A1B6J616   A0A212FLN3   A0A1Y1KTF8   A0A1B6FF15   A0A1A9UZB6   U4UHU2   A0A034W6Z8   N6TW75   A0A0P8ZQ48   W8BBB7   E0W0P6   B3MC49   B4KQR5   A0A2A3EMS1   A0A0R1DU59   A0A0K8WH42   A0A0K8UGQ7   A0A0Q5W393   B4J9N1   A0A336KQE3   D6WD88   B4PBX4   A0A0Q5VPH3   A0A0J9RKV0   A0A1B6DPR8   A0A0R3NKW5   A0A0J9RL31   A0A0A1XER0   Q8MMC6   Q0E8W1  

PDB

4W4T     E-value=1.61539e-08,     Score=143

KEGG

101740425    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0080019   GO:0016021   GO:0102965   GO:0010025   GO:0005777   GO:0035336   GO:0008340  

PANTHER

PTHR11011  

Length:

518

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

44.76507

Exp number, first 60 AAs:

0.11089

Total prob of N-in:

0.12497

outside

1  -  355

TMhelix

356  -  375

inside

376  -  464

TMhelix

465  -  487

outside

488  -  518

 

 

Pi

227.077464

Theta

162.077106

Tajima's D

1.343033

CLR

0.003158

CSRT

0.750462476876156

Interpretation

Uncertain