Silkworm Genome Informatics Database

Gene

KWMTBOMO05587

Pre Gene Modal

BGIBMGA006582

Annotation

PREDICTED:_receptor-type_tyrosine-protein_phosphatase_N2_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr10(-):5396654-5411139 View in EpiBrowser

Location in the cell

Cytoplasmic Reliability : 2.349 Nuclear Reliability : 1.655

CDS

ATGTACGGCCTGTCTTTGCGGCAGGCTCTGTGGGCGCTGGCGTTGATAAACGCGCTGGCGCCCTCGCACGCCGATGGTAACATAGGTTGCTTGTTCAGCGCACCACTGTGTGTAGAGGGCGTAGAGTGGTGCTACGATGATTTCGCCTTTGGGAAATGCATTCCGGTTTACGAGGAAGAGTCAGAAGAAGGCGCGCTCTACCGTTACGACATGGGTCCGGAGCAACTGCAATGGTTCGAAGGAGAGTTGCAACGTCTTGCAGCACGCGGCTACCGCTGGGAGCACGCCTACACCCAGTGCGTTCTGCAAGCCATGCTCCTCACACTACAACAGAACATAGATCTGAGCAACGTAAACACGAAGATATGTGAACATTTCGCTGATCCAACATTGACTTCTGACACTTCTGAAAGTGAAATTGTTAATCCAGAAATGGAACCAGAAGAGACAGCCTTTATTCGTTATACACCAAACGCTGCCGTCGGGGTTGACTCTGACTTTGCTAATGAAATTTACAACCCACCGATCGTGCCAGAAGATAACCCCAACATAGGTGATATCGAAACGGAAACTCCCAGTGATAAGCTACGAGACTTGATGCTAATGACGGACAATGAAGAGTCTCCTGTTATTTTACCATTTAACGGCTTCAGAGAACGCCTTCAAGCTGAAGGAAAGGGTCGAACCAAAACAAACGTACATCTAAACTTAATCGACAAAGAAAAGAAATCTGTGAATGAAATGATGGCTCAAAACGATCCTAATATCGGATACACAGACGAGGAGCGTTTAGGTGCGCATTTCCATCCGTCCGATATTCCGGAATCTCGGATTTATGACGAAGATTTAGACGAATTGCCTATTGATCCAGACAGCGGGGAGCTAGATGCCTACCGTGCTAAAGGTAAGCCTCCAGGGTTTGAAGGGAAGCATGGCAAAAATATGGATCGTAACATAGTGAATTATATGCGAGATATGATAAAATCTAAACCAAAACAAGATGCCATCTACGCAGAAGGTGGCCCTTTGAATCCTGAAGAATTACAAGCTGAAGATCCAGCTCATACATTAAAAAACAGCAAACATACCGAACATAACCATAATGATTTTGATTATGATCCGGCGTACGCCTACGTTTTACTTAAAAATGGATTACTCACCAATTGGGCTAAAGGAATTTCATTTATATCGAAGATTGAGGAAATGTTGGGTCTGGATAAAAACTCATTCTCGAACCCGCGAGTTGACCTACGGGAAGTGACATTCAAAGTGGAAAAAAATAATAAAGGCTACGATGCTGTTGACGTTGCAAGGCGAGTTGATGACATCAAAGATGATCTATTAAGAGAAACTGGAGCCCAGATAATTTCTACTGGAGTTGGTGACAGAAGCAAGCGTCCTATAATGCGTCATGTAGCTTCTCCGGATACTTTAATTTTCGGCTTAGAGCTACCCGTTTTCCTGGCGTTAGTTGGAAGCTTTTCTGTTTTGGTCGTAGGCGCAATTATTTTCGCTATTCTGTTGAAAAAAGACATGTCCGGAAAGAAAAAATCACAAGGCCTTTCATCTGCAGCGGAAATTGATGCAGAGGCCACAAGAGATTACCAGGAGCTATGTAGAGCACGTATGTCTGGGAAGTGGTCTGGCCAACAGACAGCAGCTAATGCGTCATCTAACCCCGCGGAGCCTGCCCAACGCATCACGTCTTTGTCACGAGAACCCGATGGAAACTCGCCTTCTACACGATCCAGCACCTCTTCATGGAGCGAAGAACCAGCTCTAACCAATATGGACATTTCAACTGGTCACATGGTCTTGGCATATATGGAAGATCACCTTCGCAACAAGGATCGCTTGGAGCAGGAGTGGCGTGCTCTGTGCGCATACGAGGCCGAACCCTGTGCTACAACTTCAGCTCTTAAGCCGGAGAATAGTGCGAAAAACAGATATGCTGATGTGCTTCCTTACGACCATTCCAGGGTTATTCTGAACACCTTATCCAACCATGTCGGATCGGATTACATCAATGCTTCGACAATTACTGACCACGACCCACGCAATCCTGCATACATCGCATCAGCTGGACCACTCCCCCACACGGCACCTGATTTCTGGCAGATGGTCTGGGAGCAAGGCTCAGTTGTCATGGTGATGTTGACTCGACTTACGGAAAACGGACAACAACTGTGCCACCGCTATTGGCCTGAGGAAGGATCTGAACTTTACCACATTTATGAGGTACACCTTGTCAGCGAGCATATTTGGTGTGATGACTACCTGGTTCGAAGCTTCTACCTGAAGAACCAACGTACCGGCGAGACCCGCACCGTCACCCAGTTCCATTTCCTCTCGTGGCCTGAGAACGGAGTACCAGCGTCGACCAAAGCTCTGTTGGAATTCAGGAGAAAGGTGAATAAGTCTTACAGAGGAAGATCTTGTCCAATCGTAGTGCACTGCAGCGATGGCGCCGGCCGCTCTGGAACGTACTGTCTGATAGACATGGTATTGAACCGGATGGCTAAAGGCGCTAAGGAGATCGACATCGCAGCCACTCTCGAGCATATCCGAGACCAGCGCACCCGCACTGTCGCTACTAAGCAGCAATTTGAGTTTGTGCTGATGGCGGTCGCTGAAGAGGATAGACTACTGGGCTTACTAGATAAAAGAAAATACTAA

Protein

MYGLSLRQALWALALINALAPSHADGNIGCLFSAPLCVEGVEWCYDDFAFGKCIPVYEEESEEGALYRYDMGPEQLQWFEGELQRLAARGYRWEHAYTQCVLQAMLLTLQQNIDLSNVNTKICEHFADPTLTSDTSESEIVNPEMEPEETAFIRYTPNAAVGVDSDFANEIYNPPIVPEDNPNIGDIETETPSDKLRDLMLMTDNEESPVILPFNGFRERLQAEGKGRTKTNVHLNLIDKEKKSVNEMMAQNDPNIGYTDEERLGAHFHPSDIPESRIYDEDLDELPIDPDSGELDAYRAKGKPPGFEGKHGKNMDRNIVNYMRDMIKSKPKQDAIYAEGGPLNPEELQAEDPAHTLKNSKHTEHNHNDFDYDPAYAYVLLKNGLLTNWAKGISFISKIEEMLGLDKNSFSNPRVDLREVTFKVEKNNKGYDAVDVARRVDDIKDDLLRETGAQIISTGVGDRSKRPIMRHVASPDTLIFGLELPVFLALVGSFSVLVVGAIIFAILLKKDMSGKKKSQGLSSAAEIDAEATRDYQELCRARMSGKWSGQQTAANASSNPAEPAQRITSLSREPDGNSPSTRSSTSSWSEEPALTNMDISTGHMVLAYMEDHLRNKDRLEQEWRALCAYEAEPCATTSALKPENSAKNRYADVLPYDHSRVILNTLSNHVGSDYINASTITDHDPRNPAYIASAGPLPHTAPDFWQMVWEQGSVVMVMLTRLTENGQQLCHRYWPEEGSELYHIYEVHLVSEHIWCDDYLVRSFYLKNQRTGETRTVTQFHFLSWPENGVPASTKALLEFRRKVNKSYRGRSCPIVVHCSDGAGRSGTYCLIDMVLNRMAKGAKEIDIAATLEHIRDQRTRTVATKQQFEFVLMAVAEEDRLLGLLDKRKY

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Uniprot

H9JAN7 A0A2A4JQT5 A0A3S2M002 A0A194PF14 A0A194QLF5 A0A1C9EGL2 + More
A0A2H1V5C2 A0A182W728

Pubmed

19121390 26354079

EMBL

BABH01008650 BABH01008651 NWSH01000874 PCG73770.1 RSAL01000092 RVE47969.1 + More
KQ459606 KPI91613.1 KQ461198 KPJ06204.1 KX778610 AON96634.1 ODYU01000764 SOQ36050.1

Proteomes

UP000005204 UP000218220 UP000283053 UP000053268 UP000053240 UP000075920 + More

PRIDE

H9JAN7

Pfam

PF11548 Receptor_IA-2 + More
PF00102 Y_phosphatase

Interpro

IPR000387   TYR_PHOSPHATASE_dom        + More
IPR038112   Receptor_IA-2_ectodomain_sf
IPR021613   Receptor_IA-2_dom
IPR000242   PTPase_domain
IPR029021   Prot-tyrosine_phosphatase-like
IPR003595   Tyr_Pase_cat
IPR016130   Tyr_Pase_AS

SUPFAM

SSF52799 SSF52799

Gene 3D

3.30.70.2470 3.90.190.10

ProteinModelPortal

H9JAN7 A0A2A4JQT5 A0A3S2M002 A0A194PF14 A0A194QLF5 A0A1C9EGL2 + More
A0A2H1V5C2 A0A182W728

PDB

2QEP E-value=2.43068e-127, Score=1170

KEGG

101738718 K07817 receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48] | (RefSeq) receptor-type tyrosine-

GO

GO:0004725 GO:0016021 GO:0006470 GO:0016311 GO:0016791 GO:0006913 GO:0007165 GO:0001664 GO:0005525 GO:0007264 GO:0003824

SignalP

Position: 1 - 24, Likelihood: 0.998000

Length:

891

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.97118

Exp number, first 60 AAs:

0.03074

Total prob of N-in:

0.00368

outside

1 - 485

TMhelix

486 - 508

inside

509 - 891

Pi

339.019763

Theta

219.931989

Tajima's D

1.78793

CLR

0.073586

CSRT

0.844607769611519

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics