Gene

KWMTBOMO05578

Pre Gene Modal

BGIBMGA006586

Annotation

PREDICTED:_alpha-scruin-like_[Plutella_xylostella]

Location

Bomo_Chr10(-):5307604-5314971      View in EpiBrowser

Full name

Beta-scruin       + More
Alpha-scruin      
Influenza virus NS1A-binding protein homolog A      

Location in the cell

Mitochondrial   Reliability : 2.523

CDS

ATGAACGTTGCTCGCATGGCGATGGGCTGCTTGAAGTACAGGGACTACATTTGGGTCGCCGGCGGCATGACGGGCGACAAGAAGAGGCCCGTCAGTAAAATCGTGGAGTGCTACAATTCAAGAACCAATGAGTGGACAGAAATACACAATCTCCGTTTTCCTCGATGTTTCACAACTCTGTTTTCAATGAATGACAAACTGTACATTGTCGGCGGAGCAGGGAAAATATCCGAAAAGGAAAAAACACCGAGTAGCGTTGGAGCCATCGATGCTTGGGATTGGAAGGAGCGAGCGTGGAAACTGGAGACGGAGATGTCGATGCCGCGTCACGGACACGCACTCGCCTACCTCGGTACTCAGCTTATAATCATAGGAGGCGTCACTACAATATACATGCGAGCACTGAATAATGTAGAATCTTATTGCTGCGAACGTGGCGCTTGGATCCGTGGGGTGGCAGCCCTACCCTCGCCACTGTCCGGTCACGGGGCAGTTACATTGCCACCTGCTTCGCTTATGTGA

Protein

MNVARMAMGCLKYRDYIWVAGGMTGDKKRPVSKIVECYNSRTNEWTEIHNLRFPRCFTTLFSMNDKLYIVGGAGKISEKEKTPSSVGAIDAWDWKERAWKLETEMSMPRHGHALAYLGTQLIIIGGVTTIYMRALNNVESYCCERGAWIRGVAALPSPLSGHGAVTLPPASLM

Description

Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats.

Similarity

Belongs to the G-protein coupled receptor 2 family.

Keywords

Kelch repeat   Repeat   Alternative splicing   Complete proteome   Cytoplasm   Cytoskeleton   Nucleus   Reference proteome  

Feature

chain  Beta-scruin
splice variant  In isoform 2.

Uniprot

H9JAP1   A0A2A4K267   A0A194PEC4   A0A1C9EGK4   A0A212F1A7   E0VM55   + More
A0A194QLG1   D6X201   A0A088AQ25   A0A0L7R7F1   A0A154PKK6   A0A310ST73   A0A2A3EIE9   A0A0C9Q771   T1HYJ3   A0A224XJB8   A0A0A9XQR7   A0A0A9XFE2   T1JEX1   A0A1B6D328   A0A1B6D0X8   A0A226F0K4   A0A1B6IAI1   A0A1B6L3Y5   A0A2R7WG18   A0A1B6ELB0   A0A1S3JCD5   A0A1S3JIH9   A0A0M8ZW88   A0A2P8Y214   Q25386   Q25390   A0A1D2MGV4   C3ZAN5   A0A2T7NUD0   H2ZIF7   A0A2T7NSQ7   A0A1A9XE02   A0A1A9ULC2   B7Q735   A0A1B0AN56   A0A1W2WBW9   F6V396   I2EYT4   T1IK99   B7P7S4   B1H341   B7QK30   A0A2D4VKD8   H6CDM2   A0A3B3RVD4   F7E9S0   A0A3B3RV90   A0A1L8GGL0   A0A2C9JHJ4   A0A369AS77   K1PF79   A0A1H3LX36   A0A3B1J6C4   W5LCD6   I3JUM7   A0A2F0BLQ3   A0A1H6LGE8   A0A1A8GGQ9   A0A2D0NIP4   A0A1D2ND91   A0A2P6L5B7   A0A3S0ZGP4   A0A0B6YQQ6   A0A2G9RG49   A0A1B0D3K8   A0A3Q2X2Z9   A0A293L487   A0A2D4JUG9   Q5RG82   A0A3Q1CFF6   A0A3P8ST07   A0A3P8PBG7   A0A3Q4HXC5   V9KFA6   A0A3B4G620   A0A3Q4N4R0   A0A3Q2WR22   A0A3P8PBE6   A0A3P9CQZ9   A0A3Q2WH97   A0A3Q2WGN5   A0A3P9CQZ4   A0A1A8LMJ6  

Pubmed

19121390    26354079    22118469    20566863    18362917    19820115    + More
25401762    29403074    7593276    7822422    27289101    18563158    12481130    15114417    29337314    22461553    29240929    20431018    27762356    15562597    22992520    25329095    25186727    23594743    24402279   

EMBL

BABH01008646    BABH01008647    NWSH01000287    PCG77732.1    KQ459606    KPI91617.1    + More
KX778610    AON96630.1    AGBW02010922    OWR47519.1    DS235289    EEB14461.1    KQ461198    KPJ06209.1    KQ971371    EFA10195.2    KQ414639    KOC66800.1    KQ434936    KZC12004.1    KQ760221    OAD61375.1    KZ288232    PBC31478.1    GBYB01009993    JAG79760.1    ACPB03020118    GFTR01008307    JAW08119.1    GBHO01024154    JAG19450.1    GBHO01024157    GBRD01000588    JAG19447.1    JAG65233.1    JH432130    GEDC01017220    JAS20078.1    GEDC01018015    JAS19283.1    LNIX01000001    OXA62944.1    GECU01023836    JAS83870.1    GEBQ01021525    JAT18452.1    KK854775    PTY18604.1    GECZ01031078    JAS38691.1    KQ435840    KOX71326.1    PYGN01001031    PSN38305.1    Z47541    Z38132    LJIJ01001321    ODM92141.1    GG666602    EEN50438.1    PZQS01000009    PVD24789.1    PVD24186.1    ABJB010120763    ABJB010128823    ABJB010186399    ABJB010399346    ABJB010500663    ABJB010574955    ABJB010662129    ABJB010675563    ABJB010858327    ABJB011008628    DS872016    EEC14657.1    JXJN01000723    JXJN01000724    EAAA01000057    CP002961    AFK04837.1    JH430450    ABJB010017723    ABJB010110186    ABJB010381258    ABJB010457894    ABJB010632335    ABJB010771594    ABJB010918446    ABJB010966307    ABJB010978255    ABJB010990706    DS653188    EEC02646.1    BC161238    AAI61238.1    ABJB010219446    ABJB010643383    ABJB010786116    ABJB010915131    DS956570    EEC19202.1    NYVD01000117    MAB14385.1    JH601044    EHS59321.1    AAMC01009141    AAMC01009142    AAMC01009143    AAMC01009144    AAMC01009145    AAMC01009146    AAMC01009147    AAMC01009148    CM004473    OCT82980.1    QPJT01000023    RCX12202.1    JH816123    EKC20248.1    FNOY01000054    SDY68926.1    AERX01012990    NTJE010292210    MBW03851.1    FNXF01000006    SEH87643.1    HAEB01016195    HAEC01002139    SBQ70216.1    PDUD01000001    PHN08375.1    LJIJ01000088    ODN03055.1    MWRG01001696    PRD33774.1    RQTK01000506    RUS78504.1    HACG01011759    CEK58624.1    KV947546    PIO26241.1    AJVK01002940    GFWV01000737    MAA25467.1    IACL01012384    LAB00098.1    BX957305    BC046068    BC066513    JW863947    AFO96464.1    HAEF01007657    HAEG01005920    SBR45114.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000009046    UP000053240    + More
UP000007266    UP000005203    UP000053825    UP000076502    UP000242457    UP000015103    UP000198287    UP000085678    UP000053105    UP000245037    UP000094527    UP000001554    UP000245119    UP000007875    UP000092443    UP000078200    UP000001555    UP000092460    UP000008144    UP000002875    UP000005078    UP000261540    UP000008143    UP000186698    UP000076420    UP000253034    UP000005408    UP000198640    UP000018467    UP000005207    UP000199371    UP000223913    UP000271974    UP000092462    UP000264840    UP000000437    UP000257160    UP000265080    UP000265100    UP000261580    UP000261460    UP000265160   

PRIDE

H9JAP1    Q25386    Q25390    Q5RG82   

Pfam

PF01344   Kelch_1        + More
PF00651   BTB
PF07707   BACK
PF00612   IQ
PF07646   Kelch_2
PF01841   Transglut_core
PF05705   DUF829
PF15881   DUF4734
PF00754   F5_F8_type_C
PF02210   Laminin_G_2
PF00002   7tm_2
PF00053   Laminin_EGF
PF00008   EGF
PF01825   GPS
PF16489   GAIN
PF00400   WD40

Interpro

IPR006652   Kelch_1        + More
IPR015915   Kelch-typ_b-propeller       
IPR011333   SKP1/BTB/POZ_sf       
IPR000210   BTB/POZ_dom       
IPR011705   BACK       
IPR017096   BTB-kelch_protein       
IPR000048   IQ_motif_EF-hand-BS       
IPR011498   Kelch_2       
IPR029058   AB_hydrolase       
IPR038765   Papain-like_cys_pep_sf       
IPR002931   Transglutaminase-like       
IPR008547   DUF829_TMEM53       
IPR030104   IPP       
IPR030609   KLHL33       
IPR030594   KLHL17       
IPR031750   DUF4734       
IPR035979   RBD_domain_sf       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR011043   Gal_Oxase/kelch_b-propeller       
IPR000421   FA58C       
IPR013783   Ig-like_fold       
IPR008979   Galactose-bd-like_sf       
IPR030605   KLHL8       
IPR003961   FN3_dom       
IPR036116   FN3_sf       
IPR000203   GPS       
IPR002049   Laminin_EGF       
IPR001879   GPCR_2_extracellular_dom       
IPR013320   ConA-like_dom_sf       
IPR001881   EGF-like_Ca-bd_dom       
IPR032471   GAIN_dom_N       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       
IPR000832   GPCR_2_secretin-like       
IPR017981   GPCR_2-like       
IPR001791   Laminin_G       
IPR000742   EGF-like_dom       
IPR013032   EGF-like_CS       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR017986   WD40_repeat_dom       
IPR001680   WD40_repeat       

SUPFAM

SSF117281   SSF117281        + More
SSF54695   SSF54695       
SSF54001   SSF54001       
SSF53474   SSF53474       
SSF54928   SSF54928       
SSF50965   SSF50965       
SSF49265   SSF49265       
SSF49785   SSF49785       
SSF49899   SSF49899       
SSF50978   SSF50978       

Gene 3D

2.120.10.80     3.40.50.1820     3.30.70.330     2.60.120.260     2.60.40.10     2.130.10.10    

CDD

cd00063  FN3

ProteinModelPortal

H9JAP1   A0A2A4K267   A0A194PEC4   A0A1C9EGK4   A0A212F1A7   E0VM55   + More
A0A194QLG1   D6X201   A0A088AQ25   A0A0L7R7F1   A0A154PKK6   A0A310ST73   A0A2A3EIE9   A0A0C9Q771   T1HYJ3   A0A224XJB8   A0A0A9XQR7   A0A0A9XFE2   T1JEX1   A0A1B6D328   A0A1B6D0X8   A0A226F0K4   A0A1B6IAI1   A0A1B6L3Y5   A0A2R7WG18   A0A1B6ELB0   A0A1S3JCD5   A0A1S3JIH9   A0A0M8ZW88   A0A2P8Y214   Q25386   Q25390   A0A1D2MGV4   C3ZAN5   A0A2T7NUD0   H2ZIF7   A0A2T7NSQ7   A0A1A9XE02   A0A1A9ULC2   B7Q735   A0A1B0AN56   A0A1W2WBW9   F6V396   I2EYT4   T1IK99   B7P7S4   B1H341   B7QK30   A0A2D4VKD8   H6CDM2   A0A3B3RVD4   F7E9S0   A0A3B3RV90   A0A1L8GGL0   A0A2C9JHJ4   A0A369AS77   K1PF79   A0A1H3LX36   A0A3B1J6C4   W5LCD6   I3JUM7   A0A2F0BLQ3   A0A1H6LGE8   A0A1A8GGQ9   A0A2D0NIP4   A0A1D2ND91   A0A2P6L5B7   A0A3S0ZGP4   A0A0B6YQQ6   A0A2G9RG49   A0A1B0D3K8   A0A3Q2X2Z9   A0A293L487   A0A2D4JUG9   Q5RG82   A0A3Q1CFF6   A0A3P8ST07   A0A3P8PBG7   A0A3Q4HXC5   V9KFA6   A0A3B4G620   A0A3Q4N4R0   A0A3Q2WR22   A0A3P8PBE6   A0A3P9CQZ9   A0A3Q2WH97   A0A3Q2WGN5   A0A3P9CQZ4   A0A1A8LMJ6  

PDB

5YY8     E-value=4.93872e-09,     Score=141

KEGG

101738452    no KO assigned | (RefSeq) alpha-scruin

GO

GO:0003676   GO:0015629   GO:0005509   GO:0004930   GO:0007166   GO:0016021   GO:0005634   GO:0005737   GO:0005515   GO:0042254   GO:0003677   GO:0003899   GO:0006913   GO:0007165   GO:0001664   GO:0005525   GO:0007264   GO:0003824  

PANTHER

PTHR24412:SF35   PTHR45632:SF14   PTHR24412:SF168   PTHR24412:SF403  

Subcellular location

Cytoplasm   Associated with actin filaments.   With evidence from 1 publications.
Cytoskeleton   Associated with actin filaments.   With evidence from 1 publications.
Nucleus   Associated with actin filaments.   With evidence from 1 publications.

Length:

173

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.49029

Exp number, first 60 AAs:

0.00882

Total prob of N-in:

0.70937

inside

1  -  112

TMhelix

113  -  135

outside

136  -  173

 

 

Pi

186.242997

Theta

146.060268

Tajima's D

0.998148

CLR

0.780022

CSRT

0.654217289135543

Interpretation

Uncertain