Gene

KWMTBOMO05566  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006751

Annotation

GTP-binding_nuclear_protein_Ran_[Bombyx_mori]

Location

Bomo_Chr10(+):5202642-5203984      View in EpiBrowser

Full name

GTP-binding nuclear protein      

Location in the cell

Cytoplasmic   Reliability : 2.955

CDS

ATGGCAGATGATATGCCCACATTCAAGTGTGTATTGGTAGGAGATGGTGGTACTGGCAAAACAACCTTTGTCAAAAGACATTTGACTGGAGAGTTCGAGAAAAAATACGTTGCGACTCTGGGTGTCGAAGTACATCCTCTAGTATTCCATACGAACCGCGGGCCAATTCGTTTTAATGTGTGGGACACAGCCGGACAAGAGAAGTTTGGTGGTCTTAGAGACGGATACTATATTCAAGGACAATGTGCTATCATCATGTTCGACGTAACCTCTCGAGTTACGTACAAAAATGTACCTAACTGGCATAGAGATTTGGTCCGTGTATGTGAAGGTATCCCTATTGTCTTGTGCGGAAACAAAGTGGATATTAAAGACAGAAAAGTTAAGGCGAAAACTATTGTTTTCCACAGGAAAAAGAATTTGCAGTACTACGACATTTCTGCTAAGTCAAACTACAACTTCGAAAAACCCTTCCTGTGGCTAGCTAGAAAATTAATTGGTGACGGTAACCTTGAGTTTGTTGCCATGCCTGCCCTTCTGCCACCAGAAGTTACAATGGATCCTCAATGGCAGAACCAAATTGAAAAAGATCTTCAAGATGCACAAAATACTGCTCTTCCTGAGGAAGATGAAGACTTATAA

Protein

MADDMPTFKCVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIRFNVWDTAGQEKFGGLRDGYYIQGQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEGIPIVLCGNKVDIKDRKVKAKTIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDGNLEFVAMPALLPPEVTMDPQWQNQIEKDLQDAQNTALPEEDEDL

Description

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

Similarity

Belongs to the small GTPase superfamily. Ran family.

Uniprot

Q2F5M1   D2CVL0   A0A2A4JAV2   A0A0S2MU10   A0A1E1WLF0   A0A0L7LMS4   + More
A0A194QRQ4   S4P4M1   A0A1C9EGK6   A0A212EN84   I4DJ77   A0A3S2PD56   A0A3G1T1H9   A2I472   E2BIH4   A0A154P0S4   E9J8E7   A0A310SIF0   A0A026WHC3   A0A195E562   F4WNZ0   A0A195BA77   A0A0J7KS58   A0A195EUX8   A0A158NPG7   E1ZVJ6   A0A151WRH5   A0A232EG19   K7IZ28   A0A2A3EMR5   V9IHB9   A0A087ZWI7   A0A195CNZ8   A0A0N0BJP5   A0A1B6KSN4   A0A1B6EIX3   A0A0S2LS65   A0A161MMN3   A0A069DQN0   R4FM02   A0A1D1Y5Y3   A0A0L7QVC3   A0A067QYL7   V5G541   A0A1S3DM23   N6UBX8   R4WIS2   A0A0K8TQB6   D6X0G0   A0A224XK22   A0A2H8TIS4   C4WRY3   A0A2S2P8V3   A0A2R7VNY6   A0A2S2PXW1   J9JUK1   A0A336LBS4   T1DIP6   A0A1Q3F2Y3   B0WNQ3   Q16WA1   A0A023EJU2   A0A1B0DQW0   U5ET96   A0A1Y1NIH5   J3JTV2   T1DNR4   A0A2M3Z0S7   A0A2M4A9D5   A0A182PA01   A0A182UQU8   W5JJ87   A0A182TJQ5   A0A182X6K6   A0A182KS15   Q5TX48   A0A182FG32   A0A182I3V5   A0A084VF67   A0A1W4UP75   A0A182MQH0   A0A182RB22   A0A182J0V4   A0A182XZC8   A0A182JTV6   A0A182WIY2   A0A182T6T0   B4JM41   A0A1L8DVN2   B4M768   A0A182NHD0   A0A182Q4W7   A0A2H4IQI6   A0A172Q3Z0   B4L1F0   W8C7U3   B4PYE8   G3MPP6   A0A023FVI6   A0A023FI65  

Pubmed

19121390    20044931    26227816    26354079    23622113    22118469    + More
22651552    20798317    21282665    24508170    30249741    21719571    21347285    28648823    20075255    26554926    27538518    26334808    24845553    23537049    23691247    26369729    18362917    19820115    24330624    17510324    24945155    26483478    28004739    22516182    20920257    23761445    20966253    12364791    14747013    17210077    24438588    25244985    17994087    24495485    17550304    22216098   

EMBL

BABH01008630    DQ311402    ABD36346.1    EU860296    ACN67046.1    NWSH01002311    + More
PCG68550.1    KT898145    ODYU01012697    ALO79337.1    SOQ59138.1    GDQN01003307    JAT87747.1    JTDY01000539    KOB76737.1    KQ461198    KPJ06221.1    GAIX01005909    JAA86651.1    KX778610    AON96619.1    AGBW02013697    OWR42950.1    AK401345    KQ459606    BAM17967.1    KPI91629.1    RSAL01000092    RVE47986.1    MG992402    AXY94840.1    EF070575    ABM55641.1    GL448508    EFN84506.1    KQ434792    KZC05447.1    GL769004    EFZ10904.1    KQ763441    OAD55112.1    KK107207    QOIP01000002    EZA55430.1    RLU25783.1    KQ979608    KYN20325.1    GL888243    EGI63921.1    KQ976542    KYM81099.1    LBMM01003697    KMQ93227.1    KQ981965    KYN31697.1    ADTU01022527    GL434548    EFN74765.1    KQ982807    KYQ50407.1    NNAY01004879    OXU17305.1    KZ288215    PBC32449.1    JR047805    AEY60513.1    KQ977574    KYN01834.1    KQ435713    KOX79264.1    GEBQ01025518    JAT14459.1    GECZ01031904    JAS37865.1    KT313028    KU932348    ALO64008.1    APA33984.1    GEMB01001655    JAS01508.1    GBGD01002888    JAC86001.1    ACPB03024585    GAHY01001183    JAA76327.1    GDJX01017918    JAT50018.1    KQ414727    KOC62588.1    KK852824    KDR15447.1    GALX01003286    JAB65180.1    APGK01029495    KB740735    KB631805    ENN79160.1    ERL86272.1    AK417365    BAN20580.1    GDAI01001518    JAI16085.1    KQ971372    EFA10538.1    GFTR01003601    JAW12825.1    GFXV01002228    MBW14033.1    AK339965    BAH70653.1    GGMR01012717    MBY25336.1    KK854005    PTY09066.1    GGMS01001172    MBY70375.1    ABLF02039222    ABLF02039227    UFQS01002537    UFQS01002781    UFQT01002537    UFQT01002781    SSX14227.1    SSX14652.1    SSX33642.1    GALA01000846    JAA94006.1    GFDL01013131    JAV21914.1    DS232014    EDS31894.1    CH477572    EAT38849.1    JXUM01098549    JXUM01098550    GAPW01004283    KQ564429    JAC09315.1    KXJ72291.1    AJVK01019411    AJVK01019412    GANO01002023    JAB57848.1    GEZM01001577    GEZM01001576    GEZM01001575    JAV97661.1    BT126661    AEE61624.1    GAMD01002635    JAA98955.1    GGFM01001372    MBW22123.1    GGFK01004076    MBW37397.1    ADMH02001258    GGFL01004211    ETN63358.1    MBW68389.1    AAAB01008807    EAL41718.3    APCN01000225    ATLV01012362    KE524785    KFB36611.1    AXCM01001459    CH916371    EDV91802.1    GFDF01003583    JAV10501.1    CH940653    EDW62635.1    AXCN02000896    KY270878    ASJ26359.1    KU286158    AND76907.1    CH933810    EDW06671.1    GAMC01000327    JAC06229.1    CM000162    EDX02010.1    JO843847    AEO35464.1    GBBL01001866    JAC25454.1    GBBK01003629    GBBK01003627    JAC20855.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000007151    UP000053268    + More
UP000283053    UP000008237    UP000076502    UP000053097    UP000279307    UP000078492    UP000007755    UP000078540    UP000036403    UP000078541    UP000005205    UP000000311    UP000075809    UP000215335    UP000002358    UP000242457    UP000005203    UP000078542    UP000053105    UP000015103    UP000053825    UP000027135    UP000079169    UP000019118    UP000030742    UP000007266    UP000007819    UP000002320    UP000008820    UP000069940    UP000249989    UP000092462    UP000075885    UP000075903    UP000000673    UP000075902    UP000076407    UP000075882    UP000007062    UP000069272    UP000075840    UP000030765    UP000192221    UP000075883    UP000075900    UP000075880    UP000076408    UP000075881    UP000075920    UP000075901    UP000001070    UP000008792    UP000075884    UP000075886    UP000009192    UP000002282   

PRIDE

Q2F5M1    A0A087ZWI7   

Pfam

PF00071   Ras

Interpro

IPR027417   P-loop_NTPase        + More
IPR001806   Small_GTPase       
IPR005225   Small_GTP-bd_dom       
IPR002041   Ran_GTPase       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

Q2F5M1   D2CVL0   A0A2A4JAV2   A0A0S2MU10   A0A1E1WLF0   A0A0L7LMS4   + More
A0A194QRQ4   S4P4M1   A0A1C9EGK6   A0A212EN84   I4DJ77   A0A3S2PD56   A0A3G1T1H9   A2I472   E2BIH4   A0A154P0S4   E9J8E7   A0A310SIF0   A0A026WHC3   A0A195E562   F4WNZ0   A0A195BA77   A0A0J7KS58   A0A195EUX8   A0A158NPG7   E1ZVJ6   A0A151WRH5   A0A232EG19   K7IZ28   A0A2A3EMR5   V9IHB9   A0A087ZWI7   A0A195CNZ8   A0A0N0BJP5   A0A1B6KSN4   A0A1B6EIX3   A0A0S2LS65   A0A161MMN3   A0A069DQN0   R4FM02   A0A1D1Y5Y3   A0A0L7QVC3   A0A067QYL7   V5G541   A0A1S3DM23   N6UBX8   R4WIS2   A0A0K8TQB6   D6X0G0   A0A224XK22   A0A2H8TIS4   C4WRY3   A0A2S2P8V3   A0A2R7VNY6   A0A2S2PXW1   J9JUK1   A0A336LBS4   T1DIP6   A0A1Q3F2Y3   B0WNQ3   Q16WA1   A0A023EJU2   A0A1B0DQW0   U5ET96   A0A1Y1NIH5   J3JTV2   T1DNR4   A0A2M3Z0S7   A0A2M4A9D5   A0A182PA01   A0A182UQU8   W5JJ87   A0A182TJQ5   A0A182X6K6   A0A182KS15   Q5TX48   A0A182FG32   A0A182I3V5   A0A084VF67   A0A1W4UP75   A0A182MQH0   A0A182RB22   A0A182J0V4   A0A182XZC8   A0A182JTV6   A0A182WIY2   A0A182T6T0   B4JM41   A0A1L8DVN2   B4M768   A0A182NHD0   A0A182Q4W7   A0A2H4IQI6   A0A172Q3Z0   B4L1F0   W8C7U3   B4PYE8   G3MPP6   A0A023FVI6   A0A023FI65  

PDB

2N1B     E-value=7.41475e-112,     Score=1029

KEGG

692970    K07936 GTP-binding nuclear protein Ran | (RefSeq) GTP-binding nuclear protein Ran

PATHWAY

03008    Ribosome biogenesis in eukaryotes - Bombyx mori (domestic silkworm)
03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0005525   GO:0015031   GO:0006913   GO:0003924   GO:0005634   GO:0006606   GO:0005737   GO:0000212   GO:1990498   GO:0032880   GO:0005938   GO:0007346   GO:0000132   GO:0007264   GO:0006886   GO:0007165   GO:0001664   GO:0003824  

PANTHER

PTHR24071  

Subcellular location

Nucleus  

Length:

213

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01774

Exp number, first 60 AAs:

0.00127

Total prob of N-in:

0.08702

outside

1  -  213

 

 

Pi

197.700194

Theta

198.407685

Tajima's D

-0.298377

CLR

0.782318

CSRT

0.288835558222089

Interpretation

Uncertain