Gene

KWMTBOMO05553  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006745

Annotation

laccase_2A_[Bombyx_mori]

Location

Bomo_Chr10(+):5001072-5005732      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.745

CDS

ATGAAACAGACCGAAACGTTCAACCTTGTACTCCAGCTTAATACTTTTTTGCCTTTGATTTCAGAAGCCATCAACGCCGCAGACGACCAGTCCACATCGGCATCGTGGTGGCAAGCCGGGACAGCAACACCGTTCAGGGAAACGGGCAGTAATGCGTTCTCATCCACCCATGGACTCGTTCAAACACACCCCAGCGCTGATGATCCATTCGGAACTACTTTTGGAGGAATAGGAAGTACTATAGGACCGTCATCGAATCCCTTCGCTAAAAGCGGCAGCGGTCCGCTGAGTGGAGGCGTTAGGAAGAATCCTTTGCCATCTCTAGCCAGGATCTCTAACATTAACGGAAAAGCCTCATTGAAACATTTGGATTTTACTAGTAGTGCTACCGCTGAATTGAGAAGGAACCCAGCACTGTCGGCCCCTGATGAGTGTGCCAGAGCCTGCAGGGAAAACGAACCACCAAGGATCTGTTACTATCATTTCACATTGGAGTTTTATACTGTCTTGGGAGCGGCTTGTCAAGTATGCACACCAAACGCTACGAATGTGGTCTGGTCTCATTGCCAATGCGTACTGGCCGATGGCGTCGAACGGGGTATTCTCACTGCCAACAGAATGTTACCAGGCCCTTCCATTCAAGTTTGCGAAAACGATAAAGTGGTAATTGACGTAGAGAACCATATGGAAGGTATGGAGGTGACAATCCATTGGCACGGTATTTGGCAAAGGGGATCACAATATTACGATGGTGTACCGTTTGTCACGCAATGTCCTATTCAGCAAGGGAATACTTTCAGATATCAATGGCAAGGTAATGCTGGCACTCACTTCTGGCACGCTCACACTGGACTACAGAAACTGGATGGTTTATACGGCAGCATTGTCGTTCGTCAACCTCCTTCAAAAGATCCCAACAGTCACTTATACGATTACGATTTGACCACACACGTCATGTTGATCAGTGACTGGCTCCACGAAGATGCCGCTGAAAGATACCCAGGACGTTTAGCTGTCAATACTGGACAGGACCCCGAATCTGTATTGATCAACGGAAAAGGACAATTCAGAGATCCTAACACTGGCTTCATGACCAATACTCCATTGGAAGTTTTCACAATTACTCCTGGTAGACGTTACAGGTTCAGAATGATCAATGCCTTTGCATCGGTATGCCCTGCTCAAATCACGTTTGAAGGTCACAACTTGACAGTTATTGCTACTGACGGTGAGCCAGTGCAACCCGTGCAAGTGAACACGATAATCTCGTTCTCAGGGGAACGATACGACTTTGTAATCGAAGCTAACAACATTCCCGGAGCATACTGGATCCAAGTTCGAGGTCTTGGTGAATGTGGTATTAAGAGAGCACAACAATTAGGTATCCTCAGATACGCTAGAGGACCTTACCAACCATCTTCGCTGGCCCCCACCTACGATGTCGGAATACCCCAAGGAGTGGTGATGAACCCCTTGGACGCGAGATGTAATATATCAAGAAACGATGCTATTTGCGTGAGCCAATTGAAAAACGCTCAGAACATCGACCCCGCCATCCTTCAGGAGAGACCCGACGTTAAAATCTTTTTGCCCTTCCGATTCTTCGTATACAGACCAGAGATGCTCTTCCAACCCAACACATACAACAGATACTTGGTTGCCCCTGGAGGAGACCACGTTATCAGTTTGATTGACGAAATCTCATATATGTCCCCGCCTGCTCCATTGATCAGTCAGTATGATGACATCAATCCTGACCAATTCTGTAATGGAGACAACCGACCCGCTAACTGTGGACAAAACTGCATGTGCACACACAAAGTTGACATACCTCTGAATGCTGTTGTGGAGATTGTATTGGTAGATGAAGTACAAATCGCGAACTTATCTCATCCGTTCCACTTGCACGGATATTCATACAACGTGATAGGTATCGGAAGATCACCCGACCAGAACGTTAAGAAAATTAACTTGAAGCACGCACTCGACCTCGACAGAAGAGGATTGCTCGAACGTCACCTGAAGCAAGGAGACCTTCCTCCTGCAAAAGACACCATCGCTGTTCCCAACAACGGCTACGTCATTCTCCGTTTCAGAGCCACAAATCCTGGCTTCTGGCTACTCCATTGCCACTTCCTTTTCCACATCGTCATCGGAATGAGCTTGGTGCTCCAAGTAGGCACGCAGGGCGACCTTCCCCCCGTACCCCCGAACTTCCCCACATGCGGAGACCATCTCCCAGCCATCCCACTCCACTGA

Protein

MKQTETFNLVLQLNTFLPLISEAINAADDQSTSASWWQAGTATPFRETGSNAFSSTHGLVQTHPSADDPFGTTFGGIGSTIGPSSNPFAKSGSGPLSGGVRKNPLPSLARISNINGKASLKHLDFTSSATAELRRNPALSAPDECARACRENEPPRICYYHFTLEFYTVLGAACQVCTPNATNVVWSHCQCVLADGVERGILTANRMLPGPSIQVCENDKVVIDVENHMEGMEVTIHWHGIWQRGSQYYDGVPFVTQCPIQQGNTFRYQWQGNAGTHFWHAHTGLQKLDGLYGSIVVRQPPSKDPNSHLYDYDLTTHVMLISDWLHEDAAERYPGRLAVNTGQDPESVLINGKGQFRDPNTGFMTNTPLEVFTITPGRRYRFRMINAFASVCPAQITFEGHNLTVIATDGEPVQPVQVNTIISFSGERYDFVIEANNIPGAYWIQVRGLGECGIKRAQQLGILRYARGPYQPSSLAPTYDVGIPQGVVMNPLDARCNISRNDAICVSQLKNAQNIDPAILQERPDVKIFLPFRFFVYRPEMLFQPNTYNRYLVAPGGDHVISLIDEISYMSPPAPLISQYDDINPDQFCNGDNRPANCGQNCMCTHKVDIPLNAVVEIVLVDEVQIANLSHPFHLHGYSYNVIGIGRSPDQNVKKINLKHALDLDRRGLLERHLKQGDLPPAKDTIAVPNNGYVILRFRATNPGFWLLHCHFLFHIVIGMSLVLQVGTQGDLPPVPPNFPTCGDHLPAIPLH

Similarity

Belongs to the multicopper oxidase family.

Uniprot

B5BR55   A7XQR9   H9JB50   A0A076FLX5   Q8I8Y0   A0A212F4T2   + More
D5MRR9   D4AH59   A0A2H1VVE5   A0A2A4J3K6   D5MRS1   U6A581   B4F7L6   A0A194PG16   A0A0L7LUX0   G4XHA2   A0A084WL27   A0A1W5VPG6   A0A182LS40   A0A182IZ20   Q4ZGM4   A0A182UT19   A7UU38   A0A182I1A0   Q58IU3   B4KLT3   B5B2D0   B4GBH6   A0A0J9R682   A0A0J9R6H4   B4IM24   B4LPG0   B0XBY5   B0WW28   Q7JQF6   A0A182P7P1   A1Z6F6   Q29CP8   B3N3L4   B3N1H7   B4ISZ0   A0A182YKV7   A0A182X5E6   A0A0P8XD20   A0A336LNA3   A0A182RDU7   Q86P50   A0A182WLN0   A0A1I8MAX1   A0A182U114   A0A1I8QC41   A0A034V864   T1PG09   A0A0A1WT11   W8BXM7   A0A182NK10   A0A0L0CHR0   A0A182KNW0   B4J6G7   A0A0K8VT75   A0A194QL27   A0A182FHY6   A0A0P6IU09   Q0IF14   Q58IU2   Q7Q5V9   A0A0J9R7F0   D6WE75   A0A1A9ZUU7   Q49I41   A1Z6F4   A0A1W4WWP4   B7YZT1   A0A0J9R5Z8   A0A2U8ICW4   A0A1Y1MUB4   A0A0J9TTT8   A0A1B0AMG9   A0A0B4KF30   A0A182QNY9   A0A2U8ICP2   A0A1A9YJF8   A0A0Q5WLN4   Q49I40   A0A2M4CZW5   W5JD72   A7XQS2   A0A087ZPF2   B4MQV3   A0A034V974   A0A0N0BD48   A0A1J1J067   A0A3L8DUA5   A0A0C9PH46   A0A154PKC4   B4K2F0   E9I908   A0A2A3EF34   A0A195ATS4   A0A0L7R085  

Pubmed

14614147    19168135    18477244    19121390    22118469    26354079    + More
26227816    24438588    28376914    12364791    14747013    17210077    18675911    17994087    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    17550304    25244985    25315136    25348373    25830018    24495485    26108605    20966253    26999592    17510324    18362917    19820115    16076951    28004739    20920257    23761445    30249741    21282665   

EMBL

AB379590    BAG70891.1    EU093074    ABU68465.1    BABH01008618    KJ789368    + More
AII19522.1    AY135186    AAN17507.1    AGBW02010309    OWR48758.1    AB531133    BAJ07600.1    AB499123    BAI87829.1    ODYU01004678    SOQ44817.1    NWSH01003453    PCG66268.1    AB531135    BAJ07602.1    KF479388    AHA15412.1    BK006378    DAA06287.1    KQ459606    KPI91644.1    JTDY01000047    KOB79189.1    JF811457    AEP43806.1    ATLV01024176    KE525350    KFB50921.1    KY132102    ARG47519.1    AXCM01006745    DQ011288    AAY29698.1    AAAB01008960    EDO63816.1    APCN01000047    APCN01000048    AY943928    AAX49501.1    CH933808    EDW09743.1    EU886786    ACG63789.1    CH479181    EDW31271.1    CM002911    KMY91618.1    KMY91621.1    CH480920    EDW43632.1    CH940648    EDW61219.2    DS232661    EDS44514.1    DS232136    EDS35860.1    AE013599    BT010091    AAF57332.4    AAQ22560.1    BT133179    AAF57331.3    AEZ68807.1    CH475437    EAL29272.3    CH954177    EDV59896.1    CH902656    EDV29979.2    CH891608    EDW99572.1    KPU72643.1    UFQT01000078    SSX19430.1    BT003483    AAO39486.1    GAKP01020651    GAKP01020650    JAC38302.1    KA647757    AFP62386.1    GBXI01012310    GBXI01009830    GBXI01008054    GBXI01005511    JAD01982.1    JAD04462.1    JAD06238.1    JAD08781.1    GAMC01012586    GAMC01012585    JAB93969.1    JRES01000379    KNC31786.1    CH916367    EDW01968.1    GDHF01020306    GDHF01013149    GDHF01012944    GDHF01010584    GDHF01009008    JAI32008.1    JAI39165.1    JAI39370.1    JAI41730.1    JAI43306.1    KQ461198    KPJ06237.1    GDUN01000603    JAN95316.1    CH477440    EAT40867.1    AY943929    AAX49502.1    EAA11473.4    KMY91619.1    KQ971324    EFA01166.1    AY884061    AAX84202.2    AAN16124.2    ACL83060.1    KMY91622.1    MH253688    AWK23446.1    GEZM01020491    JAV89262.1    KMY91620.1    JXJN01000432    JXJN01000433    JXJN01000434    JXJN01000435    AGB93244.1    AXCN02000495    MH253687    AWK23445.1    KQS71051.1    AY884062    AAX84203.2    GGFL01006686    MBW70864.1    ADMH02001577    ETN62011.1    EU093075    ABU68466.1    CH963849    EDW74492.1    GAKP01020652    JAC38300.1    KQ435878    KOX69942.1    CVRI01000066    CRL05915.1    QOIP01000004    RLU24055.1    GBYB01000178    JAG69945.1    KQ434943    KZC12283.1    CH919043    EDW05139.1    GL761667    EFZ22928.1    KZ288262    PBC30347.1    KQ976741    KYM75596.1    KQ414672    KOC64253.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000037510    UP000030765    + More
UP000075883    UP000075880    UP000075903    UP000007062    UP000075840    UP000009192    UP000008744    UP000001292    UP000008792    UP000002320    UP000000803    UP000075885    UP000001819    UP000008711    UP000007801    UP000002282    UP000076408    UP000076407    UP000075900    UP000075920    UP000095301    UP000075902    UP000095300    UP000075884    UP000037069    UP000075882    UP000001070    UP000053240    UP000069272    UP000008820    UP000007266    UP000092445    UP000192223    UP000092460    UP000075886    UP000092443    UP000000673    UP000005203    UP000007798    UP000053105    UP000183832    UP000279307    UP000076502    UP000242457    UP000078540    UP000053825   

PRIDE

B5BR55    A7XQR9    H9JB50    B4F7L6    Q7JQF6    A1Z6F6    + More
Q86P50    A1Z6F4   

Pfam

PF07731   Cu-oxidase_2        + More
PF00394   Cu-oxidase
PF07732   Cu-oxidase_3

Interpro

IPR002355   Cu_oxidase_Cu_BS        + More
IPR011706   Cu-oxidase_2       
IPR001117   Cu-oxidase       
IPR033138   Cu_oxidase_CS       
IPR008972   Cupredoxin       
IPR011707   Cu-oxidase_3       

SUPFAM

SSF49503   SSF49503       

Gene 3D

2.60.40.420    

ProteinModelPortal

B5BR55   A7XQR9   H9JB50   A0A076FLX5   Q8I8Y0   A0A212F4T2   + More
D5MRR9   D4AH59   A0A2H1VVE5   A0A2A4J3K6   D5MRS1   U6A581   B4F7L6   A0A194PG16   A0A0L7LUX0   G4XHA2   A0A084WL27   A0A1W5VPG6   A0A182LS40   A0A182IZ20   Q4ZGM4   A0A182UT19   A7UU38   A0A182I1A0   Q58IU3   B4KLT3   B5B2D0   B4GBH6   A0A0J9R682   A0A0J9R6H4   B4IM24   B4LPG0   B0XBY5   B0WW28   Q7JQF6   A0A182P7P1   A1Z6F6   Q29CP8   B3N3L4   B3N1H7   B4ISZ0   A0A182YKV7   A0A182X5E6   A0A0P8XD20   A0A336LNA3   A0A182RDU7   Q86P50   A0A182WLN0   A0A1I8MAX1   A0A182U114   A0A1I8QC41   A0A034V864   T1PG09   A0A0A1WT11   W8BXM7   A0A182NK10   A0A0L0CHR0   A0A182KNW0   B4J6G7   A0A0K8VT75   A0A194QL27   A0A182FHY6   A0A0P6IU09   Q0IF14   Q58IU2   Q7Q5V9   A0A0J9R7F0   D6WE75   A0A1A9ZUU7   Q49I41   A1Z6F4   A0A1W4WWP4   B7YZT1   A0A0J9R5Z8   A0A2U8ICW4   A0A1Y1MUB4   A0A0J9TTT8   A0A1B0AMG9   A0A0B4KF30   A0A182QNY9   A0A2U8ICP2   A0A1A9YJF8   A0A0Q5WLN4   Q49I40   A0A2M4CZW5   W5JD72   A7XQS2   A0A087ZPF2   B4MQV3   A0A034V974   A0A0N0BD48   A0A1J1J067   A0A3L8DUA5   A0A0C9PH46   A0A154PKC4   B4K2F0   E9I908   A0A2A3EF34   A0A195ATS4   A0A0L7R085  

PDB

5MIG     E-value=8.7223e-47,     Score=474

KEGG

100126161    no KO assigned | (RefSeq) Lac2, BmLac2; laccase 2

GO

GO:0016491   GO:0005507   GO:0052716   GO:0016021   GO:0004322   GO:0040003   GO:0005886   GO:0006826   GO:0055072   GO:0046872   GO:0004535   GO:0006974   GO:0001664   GO:0005525   GO:0007264   GO:0003824   GO:0055114  

Length:

752

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

5.176

Exp number, first 60 AAs:

0.05991

Total prob of N-in:

0.01659

outside

1  -  752

 

 

Pi

286.796102

Theta

228.00198

Tajima's D

0.86703

CLR

0.48847

CSRT

0.618269086545673

Interpretation

Uncertain