Gene

KWMTBOMO05535  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006606

Annotation

PREDICTED:_putative_aldehyde_dehydrogenase_family_7_member_A1_homolog_[Amyelois_transitella]

Location

Bomo_Chr10(-):4356939-4365347      View in EpiBrowser

Full name

Putative aldehyde dehydrogenase family 7 member A1 homolog      

Alternative Name

ALH-9

Location in the cell

Cytoplasmic   Reliability : 2.441

CDS

ATGGCTCGCAACGCATCAACAGCTTTCCTCATAGAGGACCCGAAGTACTCGTTTTTGAAGGATTTAGGTTTAAAAGAAAACAATGTTGGAGTTTTTAACGGAAAATGGAAAGCAAACGGCGAGGTAATTAAGTCTTATAGTCCGGCAAATGGCAAAGTGATAGCAGAAGTGCAAGCGGGCAGCGCAGCCGATTATGAGGCGTGCGCCAGTGCGGCACAGGAAGCGTGGCATGCGTGGGCGGAACTGCCCGCGCCTGCAAGAGGCGAGGTCGTTAGACAAATCGGAGATGCTCTAAGGGAAAACCTTCAGCCACTTGGAAAGCTAGTGTCATTAGAAATGGGTAAAATCCTGCCAGAAGCTATCGGCGAAGTGATCGAGTATATTCACGTGTGTGACTTAGCTTTGGGTCTGTCCCGCACACTCCCCGGTACTGTGTTCCCGTCAGAGCGTCCCGGACACGTCCTGATCGAAAAATGGAACCCGCTTGGTGTTGTTGGCATCATAACAGCCTTCAACTTTCCTGTGGCTGTTTTTGGATGGAATAGCGCTATCGCTATGGTTTGTGGTGACGCAACTGTTTGGAAACCATCAGAAACAACACCGCTCGTAGCCGTGGCTGTGACTAAAATTGTAGAAAGTGTGCTGCAGAAGAACAACATACCTGGTGCCATCGCATCACTGTGCGTCGGTGGTAAAGGTATCGGAGAGAAGTTGGTTAAAGACGAAAGAATGAAACTTGTTTCCTTCACGGGCAGTACCACAGTTGGTCAACAAGTCGGAGTGGAAGTTCAGAAACGTTTCGGACGTCATTTATTAGAGCTGGGTGGAAACAACGCTATTATTGTTAACGAAGACGCAAACTTGGAGCTATTTTTATCCGCTGCACTTTTCGCTTGCGCTGGCACCGCTGGACAGCGTTGTACTACTACTAGAAGACTTCTAATCCACAAAAAGTTGTATAGCGAAGTAGTAAGCCGGCTGAAGAAAGCGTACGCAGGAGTGGTGAGCAGGATCGGCGACCCGCTACTAGAAGAGACCCTGATAGGGCCACTGCACACGCCCGCGGCCGTTGACGCTTACAAGAAGACCGTGGCCGAAGCTGTCAAACTTGGTGGCAAAATCGAGTTTGGTGGGAAGATAATTGAACGTGAAGGTTACTTCGTGGAGCCGACCATAATCACAGGTCTGCCACACGACTCTCCCATTGTGAAGACGGAATGCTTCGCCCCCATCGTCTACTGCATCGAGATACCAGATCTTGAGACTGGGATCCAATACAACAACGAGGTCGAACAAGGCCTCTCCTCCAGTCTATTCACGGAGAACTTGGGGGATGTTTTCAAGTGGATCGGTCCTCACGGGTCGGATTGCGGCATCGTGAACGTGAACATCCCGACGAACGGCGCGGAGGTGGGCGGCGCGTTCGGCGGCGAGAAGGCGACGGGCGGCGGCCGGGAGTGCGGCTCCGACAGCTGGAAGAACTACATGCGCCGCGCGACCGTCACCATCAATTACTCCGGAGCCATCAAGCTAGCGCAAAACATCAAGTTCGGTGACCAGTGA

Protein

MARNASTAFLIEDPKYSFLKDLGLKENNVGVFNGKWKANGEVIKSYSPANGKVIAEVQAGSAADYEACASAAQEAWHAWAELPAPARGEVVRQIGDALRENLQPLGKLVSLEMGKILPEAIGEVIEYIHVCDLALGLSRTLPGTVFPSERPGHVLIEKWNPLGVVGIITAFNFPVAVFGWNSAIAMVCGDATVWKPSETTPLVAVAVTKIVESVLQKNNIPGAIASLCVGGKGIGEKLVKDERMKLVSFTGSTTVGQQVGVEVQKRFGRHLLELGGNNAIIVNEDANLELFLSAALFACAGTAGQRCTTTRRLLIHKKLYSEVVSRLKKAYAGVVSRIGDPLLEETLIGPLHTPAAVDAYKKTVAEAVKLGGKIEFGGKIIEREGYFVEPTIITGLPHDSPIVKTECFAPIVYCIEIPDLETGIQYNNEVEQGLSSSLFTENLGDVFKWIGPHGSDCGIVNVNIPTNGAEVGGAFGGEKATGGGRECGSDSWKNYMRRATVTINYSGAIKLAQNIKFGDQ

Catalytic Activity

an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH

Subunit

Homotetramer.

Similarity

Belongs to the aldehyde dehydrogenase family.

Keywords

Complete proteome   NAD   Oxidoreductase   Reference proteome  

Feature

chain  Putative aldehyde dehydrogenase family 7 member A1 homolog

Uniprot

H9JAR1   A0A1L8D6W1   A0A2H1W1R1   A0A2A4KAU4   A0A194QL46   A0A194PF62   + More
A0A212EY74   A0A3S2TKI7   A0A3R7PT34   D7ELD2   A0A0P4WHX6   A0A1Y1MSZ9   A0A1B6DKX3   A0A067RTG1   U4UB96   A0A131Z580   A0A224YH73   A0A023FXP2   A0A023FM91   L7MIL3   A0A2J7PU67   A0A023FZV7   J3JU23   A0A131XL32   A0A131Y0J3   A0A2J7PU79   B7PZG8   A0A1D2N791   A0A1E1X7D6   A0A151XAC8   A0A023GNF0   Q8MUI1   A0A195DXU6   A0A195FFB5   A0A1W4WMM4   F4WZK5   J9JJU4   A0A0N4YJ07   E2BDA9   A0A158NGQ7   A0A146KS57   A0A0K2TK77   A0A151IFI1   A0A195B7Q9   A0A0A9Z803   W2SVI5   A0A1I7ZRR1   A0A016TQ78   A0A016TNL6   A0A226DFV1   A0A0K8S9R5   A0A023F8I0   A0A158QLQ9   A0A026X2E2   A0A171B2K3   W6NQU0   A0A0P4VVF1   A0A0B2VVY3   R4FNV6   A0A224XLS1   A0A261AFG0   E3LYU0   V5HJW3   A0A260Z7M9   A0A2P4UYK3   A0A0P5XMC0   A0A0P5QCB1   E0VIV2   A0A2G5URT8   A0A1I7T8J6   A0A0N8C2V9   A0A0P6GFA1   A0A0P5BNY5   P46562   A0A0P5QS09   A0A0P5UMV5   A0A2A2M030   A0A0P5KJQ3   A0A0P5QI95   A0A2A2J5L8   A0A0P5CXT3   A0A0P5BT87   G0P3Z6   A0A0N7ZW07   A0A3L8DTP7   A0A0V0GCN4   A0A1B6KGI0   V4CF63   T1EMF7   A0A147BA64   E1ZV54   R7UJH9   A0A2R5LMD5   A0A310SIU3   A0A0N8CIF0   A0A0K0CZL3   F1KZ18   A0A147BA61   A0A0D6LZV4   A0A3B3SXZ7  

EC Number

1.2.1.3

Pubmed

19121390    26354079    22118469    18362917    19820115    28004739    + More
24845553    23537049    26830274    28797301    25576852    22516182    28049606    27289101    28503490    14533688    21719571    20798317    21347285    26823975    25401762    26392177    25730766    25474469    24508170    27129103    25765539    26114425    26394399    20566863    9851916    30249741    23254933    21685128    29240929   

EMBL

BABH01008556    BABH01008557    GEYN01000004    JAV02125.1    ODYU01005735    SOQ46886.1    + More
NWSH01000001    PCG81106.1    KQ461198    KPJ06257.1    KQ459606    KPI91663.1    AGBW02011611    OWR46435.1    RSAL01000081    RVE48596.1    QCYY01001677    ROT76284.1    DS497833    EFA11998.1    GDRN01049060    JAI66612.1    GEZM01028111    JAV86457.1    GEDC01011006    JAS26292.1    KK852473    KDR23109.1    KB632277    ERL91199.1    GEDV01002642    JAP85915.1    GFPF01005870    MAA17016.1    GBBL01001018    JAC26302.1    GBBK01001665    JAC22817.1    GACK01001936    JAA63098.1    NEVH01021208    PNF19873.1    GBBL01001027    JAC26293.1    BT126735    AEE61697.1    GEFH01001666    JAP66915.1    GEFM01003017    JAP72779.1    PNF19876.1    ABJB010066274    ABJB010392436    ABJB010887651    ABJB010911375    ABJB010912526    ABJB011033177    ABJB011058718    ABJB011064200    DS825893    EEC11990.1    LJIJ01000180    ODN00945.1    GFAC01004018    JAT95170.1    KQ982339    KYQ57325.1    GBBM01000059    JAC35359.1    AF522285    AAM81354.1    KQ980107    KYN17646.1    KQ981625    KYN39078.1    GL888480    EGI60280.1    ABLF02025474    UYSL01022468    VDL80519.1    GL447585    EFN86337.1    ADTU01015170    GDHC01020839    JAP97789.1    HACA01009067    CDW26428.1    KQ977793    KYM99656.1    KQ976574    KYM80282.1    GBHO01003573    JAG40031.1    KI662931    ETN72801.1    JARK01001423    EYC04573.1    EYC04574.1    LNIX01000020    OXA44059.1    GBRD01016511    GBRD01015813    JAG50013.1    GBBI01001036    JAC17676.1    UZAF01016568    VDO30379.1    KK107054    EZA61559.1    GEMB01000356    JAS02765.1    CAVP010058389    CDL94567.1    GDKW01001852    JAI54743.1    JPKZ01000860    KHN85115.1    ACPB03014677    GAHY01000418    JAA77092.1    GFTR01007046    JAW09380.1    NIPN01000233    OZF96700.1    DS268419    EFO86805.1    GANP01000503    JAB83965.1    NMWX01000288    OZF81395.1    LFJK02001469    POM30125.1    GDIP01070003    JAM33712.1    GDIQ01122736    JAL28990.1    DS235206    EEB13308.1    PDUG01000003    PIC42163.1    GDIQ01120187    JAL31539.1    GDIQ01044374    JAN50363.1    GDIP01181932    JAJ41470.1    BX284603    GDIQ01120136    JAL31590.1    GDIP01110789    JAL92925.1    LIAE01006288    PAV91881.1    GDIQ01184304    GDIQ01184303    JAK67422.1    GDIQ01120188    JAL31538.1    LIAE01010657    PAV57080.1    GDIP01180229    JAJ43173.1    GDIP01180230    JAJ43172.1    GL380055    EGT44402.1    GDIP01207081    JAJ16321.1    QOIP01000004    RLU23797.1    GECL01000999    JAP05125.1    GEBQ01029409    JAT10568.1    KB200701    ESP00645.1    AMQM01007213    KB097587    ESN93829.1    GEIB01000102    JAR87658.1    GL434441    EFN74913.1    AMQN01007332    KB300467    ELU06714.1    GGLE01006523    MBY10649.1    KQ767664    OAD53362.1    GDIP01128647    JAL75067.1    JI168326    ADY43122.1    GEIB01000129    JAR87641.1    KE124839    EPB77344.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000283053    + More
UP000283509    UP000007266    UP000027135    UP000030742    UP000235965    UP000001555    UP000094527    UP000075809    UP000078492    UP000078541    UP000192223    UP000007755    UP000007819    UP000038043    UP000271162    UP000008237    UP000005205    UP000078542    UP000078540    UP000095287    UP000024635    UP000198287    UP000038042    UP000268014    UP000053097    UP000025227    UP000031036    UP000015103    UP000216463    UP000008281    UP000216624    UP000237256    UP000009046    UP000230233    UP000095282    UP000001940    UP000218231    UP000008068    UP000279307    UP000030746    UP000015101    UP000000311    UP000014760    UP000035642    UP000261540   

PRIDE

H9JAR1    B7PZG8    V5HJW3    P46562   

Pfam

PF00171   Aldedh        + More
PF11326   DUF3128
PF00326   Peptidase_S9
PF08389   Xpo1
PF03810   IBN_N

Interpro

IPR016161   Ald_DH/histidinol_DH        + More
IPR016163   Ald_DH_C       
IPR029510   Ald_DH_CS_GLU       
IPR015590   Aldehyde_DH_dom       
IPR016162   Ald_DH_N       
IPR021475   DUF3128       
IPR001375   Peptidase_S9       
IPR029058   AB_hydrolase       
IPR011042   6-blade_b-propeller_TolB-like       
IPR016024   ARM-type_fold       
IPR013598   Exportin-1/Importin-b-like       
IPR001494   Importin-beta_N       

SUPFAM

SSF53720   SSF53720        + More
SSF53474   SSF53474       
SSF48371   SSF48371       

Gene 3D

3.40.309.10     3.40.605.10     2.120.10.30     3.40.50.1820    

ProteinModelPortal

H9JAR1   A0A1L8D6W1   A0A2H1W1R1   A0A2A4KAU4   A0A194QL46   A0A194PF62   + More
A0A212EY74   A0A3S2TKI7   A0A3R7PT34   D7ELD2   A0A0P4WHX6   A0A1Y1MSZ9   A0A1B6DKX3   A0A067RTG1   U4UB96   A0A131Z580   A0A224YH73   A0A023FXP2   A0A023FM91   L7MIL3   A0A2J7PU67   A0A023FZV7   J3JU23   A0A131XL32   A0A131Y0J3   A0A2J7PU79   B7PZG8   A0A1D2N791   A0A1E1X7D6   A0A151XAC8   A0A023GNF0   Q8MUI1   A0A195DXU6   A0A195FFB5   A0A1W4WMM4   F4WZK5   J9JJU4   A0A0N4YJ07   E2BDA9   A0A158NGQ7   A0A146KS57   A0A0K2TK77   A0A151IFI1   A0A195B7Q9   A0A0A9Z803   W2SVI5   A0A1I7ZRR1   A0A016TQ78   A0A016TNL6   A0A226DFV1   A0A0K8S9R5   A0A023F8I0   A0A158QLQ9   A0A026X2E2   A0A171B2K3   W6NQU0   A0A0P4VVF1   A0A0B2VVY3   R4FNV6   A0A224XLS1   A0A261AFG0   E3LYU0   V5HJW3   A0A260Z7M9   A0A2P4UYK3   A0A0P5XMC0   A0A0P5QCB1   E0VIV2   A0A2G5URT8   A0A1I7T8J6   A0A0N8C2V9   A0A0P6GFA1   A0A0P5BNY5   P46562   A0A0P5QS09   A0A0P5UMV5   A0A2A2M030   A0A0P5KJQ3   A0A0P5QI95   A0A2A2J5L8   A0A0P5CXT3   A0A0P5BT87   G0P3Z6   A0A0N7ZW07   A0A3L8DTP7   A0A0V0GCN4   A0A1B6KGI0   V4CF63   T1EMF7   A0A147BA64   E1ZV54   R7UJH9   A0A2R5LMD5   A0A310SIU3   A0A0N8CIF0   A0A0K0CZL3   F1KZ18   A0A147BA61   A0A0D6LZV4   A0A3B3SXZ7  

PDB

2JG7     E-value=6.26332e-157,     Score=1423

KEGG

101735616    K14085 aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] | (RefSeq) putative a

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00071    Fatty acid degradation - Bombyx mori (domestic silkworm)
00260    Glycine, serine and threonine metabolism - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
00310    Lysine degradation - Bombyx mori (domestic silkworm)
00330    Arginine and proline metabolism - Bombyx mori (domestic silkworm)
00340    Histidine metabolism - Bombyx mori (domestic silkworm)
00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00410    beta-Alanine metabolism - Bombyx mori (domestic silkworm)
00561    Glycerolipid metabolism - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016620   GO:0016491   GO:0004029   GO:0043878   GO:0008236   GO:0006081   GO:0005634   GO:0043010   GO:0051216   GO:0033339   GO:0008152   GO:0006281   GO:0006974   GO:0001664   GO:0005525   GO:0007264   GO:0003824   GO:0055114  

Subcellular location

Nucleus  

Length:

520

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

4.0466

Exp number, first 60 AAs:

0

Total prob of N-in:

0.15399

outside

1  -  520

 

 

Pi

217.20182

Theta

173.291122

Tajima's D

0.527707

CLR

0.712899

CSRT

0.521473926303685

Interpretation

Uncertain