Gene

KWMTBOMO05503

Pre Gene Modal

BGIBMGA006621

Annotation

PREDICTED:_ubiquitin-protein_ligase_E3B_[Amyelois_transitella]

Location

Bomo_Chr10(-):3718624-3737182      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 2.205

CDS

ATGTTCTCTAAAGATTTTACAAGTAAAGAGTCATTCTTAGAACAAACAAAAGCTGCTCGGGAAGAGCGGGCTTTGGAAAAGAAACGAGAAGCTTCAGTAGTAAAAATCCAGGCTCTTGTACGGGGCTGGTTACAGAGACATAAGTTCGTCAAGATAATTTTAAATGAATTTGATGAATTACTATTACAAGCATCAGATGGTTCTCATGATGATACACAAAAATCTACTGAACTCCTTCCTGCACTATCTGTGTTCAAGTCATCTTGCCGTTTATTAATTGTGTTTGATGGTGAAAGAGACAGAAAAAGATTTGAAAAACTTTGCAAATATATCACCAATAGTCTACATTCGGAGTCCATTAAATTGTCTTATGTTGGAGTTTTTCTTAATAAGGAGTACAGTTTAAGATGGATATCACATATAAAAGATGTTCTGTTTAAATGTTGCCAATACCTTGAACAGCTTAAACCAGAATCTCCCATGGATATGCAGAGCATTCTTATTCATCTCCATACACTACTTGCCTACACTGGGAGCAGCACATGGGCACTGACGCGCCTTAAAAACTTTGAAAAGTTAAGAGGCGGCATGAATCAACTCTGTGCTAATGTCATGGGATCACTGTTTCATAAAGGATATTACTTAACCTTAAAATCGTTATTGTTGCGTGGTCTGTGTCGGGAAAAAGTGTTCCTCAAGAATATTTCCTTAACCGCCATAGTGACATTATCACTGCGACCACTTATATCAGCACAATTTTCCGAGAAACTACTCACAATGTACATAATCCAGATTTTGTCAGTTCCAACACTAGTCTATCAAATGCAGCAACTTTCTCCTGAATCAATAGCAGCATATAGAACTCATTCAATGTTCGATAAAAGCATAGAGTTTTTGAGCACCGATCAAAACATGCGTATTGTATTCAATACATTAGAAGGGAACTATGCACTTTGTCTTCTCGGAAATCTCATACAGTTGGCACACTTAGAAAAAGATCATGCTATGAAGGAAACTTATTACCCTGCATTCATATTAGTATCTACACGTTTCTTAGACTCATGCCAGCAATATGTCGTGTGCAAGAAAGGAAATCTTAGCAACTGGCATCCCATCTTGGGATGGTTTTCACAAAGCTTGGACGCGTACTTGCCTCATGCTATGACCAATCTGAGAAATCAGTTATCTTTGTTATGGGGAACTCAGTTACTCAATAAAATCCTAGCTGTTCCTCTAAAAGAGATGTTAGATGCTGGTATTACAGCTGAAGAGGGCGCTGGACCGTCACAGCCATCTACTCCCGTGCAAAGTAATAATCCTGCTGCATTTATAAGGAGAGCTATTGAGGCTAGGACCAACAGGTCCAATTCAAGCAAAAACTTTAGAAAATTAGGATCGCCGGATTGCACGAAAGCTGCGTTAATTTGTTCTATGTACCAAACTGCTCTGCAAACTATGACTCAAGTGAAACTAGATATTCTAACAGGGTTAAGCAATCAGGAGAATATATTGTATTCATTATGGCAATTTCTCTGTACTTTGGGACCAAACTGTGGATTGAAATCCTACCTCGATTTGTTAGCCGTTAACACAAAGACCTCGGCTCCAGAATTTCAAATGTTGGTGCTATTTGCGGACTGCATGACTCATTATGTTACAATTTTAGATGATATGGAAATGTATGAGAAACAGGATCCTTTTAAACTGCAAGATTTCATAAACATGTCACAGTTCCTGAATATGTTTGTCTACAAAACGATTATGGGACAGCTTTTTGATCTCAAAACAATCCAAAGCAATGATTTATTTAATTCGCTGCACACGCTACTGCTGGTGCTGTACCGTCGCGACTGCCGGCGCTCGTACACGCCCGCCCACCACTGGCTCGTTAAGGAGATACGGGAGGGGCAGTTCATGTCCGATCTGGAGAAGGGCAAGAAACCGCAGCAGATGCTAGTACAAAAGACTCCTCACATGATCGCTCACGGAGAAAGGGTCCGATTGTTCCGGAGGGCTGTCGCTGATGAAAAGGTGGTGCTGGGGCTGACGGAGAGCGCGTGCGGCGGGCGCTCGACGCTGGTGACGGTGCGGCGCGCGCGGCTGGTGGAGGACGGCTACCGGCAGCTGGCGGCGCTGCCGTCCCGCGCGCTGCGGGGCTGCGTGCGCGTGCGCTTCATCAACGAGCAGGGACTCGACGAAGCCGGCATCGACCAGGACGGCGTGTTCAAGGAATTTCTCGAAGAAACAATAAAACGCGTGTTCGATCCATCTCTGAATCTGTTCCGTGTGACGAGCGAGGAGCGCCTGTACCCGTCGCCGACGTCGTGCCTGCAAGAGAACCATCTTCAACTCTTCGAGTTCATCGGCAGGATGCTAGGGAAAGCTGTTTATGAGGGCATCGTGGTGGACGTCCCGTTCGCGTCGTTCTTCCTGAGTCAAGTCCTGGGCCAGACCCAGCAGGCGCTGTACAGCTGGATCGACGAGCTGCCCTCCCTCGACCGCGACCTCTATCGGAGTCTCACATACATCAAACACTTTCAGGGAGATATTTGTTCGCTGGAGCTGACGTTCTCCGTGGATGAGGAACGTCTGGGGGAAATAGTGACGCACGAGCTGGTGCCGGGCGGTAAAGGCATCCCCGTCACCAACGAGAACAAAATAAACTACATTCACCTGATGGCTCATTTCCGGATGCACATGCAAATCAAGGACCAGACGAACGCTTTCATCAAAGGGTTCAGAACCATCATCAACCCCGAGTGGCTTTCGTTGTTCTCCACCCCAGAGCTGCAGCGGCTGATCAGCGGCGACAACGTGCCCCTGGACCTGCGCGACCTGCGCCGCCACACGCAGTACTACGGCGGCTTCCACGACTCGCACCGCGTCGTCTGCTGGCTGTGGGACGTGCTGCAGCGCGACTTCACCGAGCACGAGCGCGCCATGTTCCTCAAGTTTGTGACGTCATGCTCGAAGCCGCCTGTACTTGGATTCGCCCATCTAAAGCCCCCGTTCTCGATACGGTGCGTTGAAGTTGGCGACGATGAAGACACCGGAGACACCATAGGCAGCGTGATTCGCGGCTTCTTCACGATAAGGAAGAAGGACCCTCTGAACCGGCTGCCGACCTCGTCGACCTGCTTCAACCTGCTCAAGCTGCCCAACTACCAGAAGCGGAGCACGCTGCGCGACAAGCTGCGGTACGCGGTCAACAGCAACACCGGCTTCGAACTGTCTTAG

Protein

MFSKDFTSKESFLEQTKAAREERALEKKREASVVKIQALVRGWLQRHKFVKIILNEFDELLLQASDGSHDDTQKSTELLPALSVFKSSCRLLIVFDGERDRKRFEKLCKYITNSLHSESIKLSYVGVFLNKEYSLRWISHIKDVLFKCCQYLEQLKPESPMDMQSILIHLHTLLAYTGSSTWALTRLKNFEKLRGGMNQLCANVMGSLFHKGYYLTLKSLLLRGLCREKVFLKNISLTAIVTLSLRPLISAQFSEKLLTMYIIQILSVPTLVYQMQQLSPESIAAYRTHSMFDKSIEFLSTDQNMRIVFNTLEGNYALCLLGNLIQLAHLEKDHAMKETYYPAFILVSTRFLDSCQQYVVCKKGNLSNWHPILGWFSQSLDAYLPHAMTNLRNQLSLLWGTQLLNKILAVPLKEMLDAGITAEEGAGPSQPSTPVQSNNPAAFIRRAIEARTNRSNSSKNFRKLGSPDCTKAALICSMYQTALQTMTQVKLDILTGLSNQENILYSLWQFLCTLGPNCGLKSYLDLLAVNTKTSAPEFQMLVLFADCMTHYVTILDDMEMYEKQDPFKLQDFINMSQFLNMFVYKTIMGQLFDLKTIQSNDLFNSLHTLLLVLYRRDCRRSYTPAHHWLVKEIREGQFMSDLEKGKKPQQMLVQKTPHMIAHGERVRLFRRAVADEKVVLGLTESACGGRSTLVTVRRARLVEDGYRQLAALPSRALRGCVRVRFINEQGLDEAGIDQDGVFKEFLEETIKRVFDPSLNLFRVTSEERLYPSPTSCLQENHLQLFEFIGRMLGKAVYEGIVVDVPFASFFLSQVLGQTQQALYSWIDELPSLDRDLYRSLTYIKHFQGDICSLELTFSVDEERLGEIVTHELVPGGKGIPVTNENKINYIHLMAHFRMHMQIKDQTNAFIKGFRTIINPEWLSLFSTPELQRLISGDNVPLDLRDLRRHTQYYGGFHDSHRVVCWLWDVLQRDFTEHERAMFLKFVTSCSKPPVLGFAHLKPPFSIRCVEVGDDEDTGDTIGSVIRGFFTIRKKDPLNRLPTSSTCFNLLKLPNYQKRSTLRDKLRYAVNSNTGFELS

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Uniprot

H9JAS6   A0A2A4JSK5   A0A3S2LU36   A0A2H1VCW6   A0A194QJG8   A0A194RNQ0   + More
A0A1E1W0Y0   A0A067QF96   A0A1Y1M0V9   A0A0C9RVD4   D6WZG6   A0A1W4XID8   A0A1B6LAX7   A0A1B6DG25   E2A4W1   A0A1B6GPJ5   A0A195E7U6   A0A195FKX1   A0A158NET2   A0A151IPW0   A0A0M8ZRH7   A0A0L7RJ98   A0A146L582   A0A088AVT6   A0A195AVU4   A0A3L8DDN0   A0A026W354   A0A154PKX7   A0A0V0G7J2   A0A151XIH1   A0A224XIP5   A0A0P4W2A9   A0A023F3A6   E0VIW0   E2B797   F4WED5   A0A1Z5LFR7   Q17BV9   A0A1S4F8R5   A0A182RUZ5   Q7Q6E5   A0A182Y2X1   A0A084VUL1   A0A182IR09   A0A182SW83   A0A182KDQ3   A0A182PPA2   A0A182VKY6   A0A182KPU4   A0A182QS02   A0A1E1XJI9   W5J243   A0A182FE37   A0A182NMG8   A0A1W4X7R7   T1IRU6   A0A182MTR3   A0A1Q3G3I3   A0A1Q3G3J5   A0A1Q3G3K2   A0A0P4WEM7   A0A131XP35   A0A1B0GJP7   A0A182I226   A0A2R5LJN6   A0A2R2MLY1   L7MI96   E9G670   A0A0P5ZVZ2   A0A0P5PK82   A0A0P5G0S3   A0A0P5CXQ5   A0A0N8AV97   A0A0N8ARU2   A0A0N8C4D0   A0A0P5G8L6   A0A0P5K155   A0A1Y1M0Y6   A0A0P5J799   A0A0P4XJ66   A0A0P5FQ36   A0A0P5JIU3   A0A0A9Y2C9   A0A0P5D3P8   A0A0P6BGA4   A0A0P5MC68   A0A0P4YZ98   A0A0N8ATA4   A0A1I8MU84   B4LEU9   A0A0L8FZX9   A0A0L8G078   V4C9W7   A0A1I8PQI6   A0A182GT51   V5H4K6   B4N6P0   A0A0Q9WSI9   A0A336K722   T1K8E1  

Pubmed

19121390    26354079    24845553    28004739    18362917    19820115    + More
20798317    21347285    26823975    30249741    24508170    27129103    25474469    20566863    21719571    28528879    17510324    12364791    14747013    17210077    25244985    24438588    20966253    29209593    20920257    23761445    29652888    25576852    21292972    25401762    25315136    17994087    23254933    26483478    25765539   

EMBL

BABH01008492    BABH01008493    BABH01008494    NWSH01000746    PCG74443.1    RSAL01000201    + More
RVE44444.1    ODYU01001875    SOQ38690.1    KQ458793    KPJ05060.1    KQ459984    KPJ19039.1    GDQN01010465    JAT80589.1    KK853689    KDQ97279.1    GEZM01042871    JAV79512.1    GBYB01012850    GBYB01012851    JAG82617.1    JAG82618.1    KQ971372    EFA09707.1    GEBQ01019161    JAT20816.1    GEDC01012708    JAS24590.1    GL436754    EFN71530.1    GECZ01005440    JAS64329.1    KQ979479    KYN21290.1    KQ981490    KYN41315.1    ADTU01013645    KQ976806    KYN08191.1    KQ435922    KOX68486.1    KQ414582    KOC70899.1    GDHC01015600    JAQ03029.1    KQ976736    KYM76089.1    QOIP01000010    RLU18018.1    KK107455    EZA50502.1    KQ434936    KZC11880.1    GECL01002102    JAP04022.1    KQ982080    KYQ60213.1    GFTR01008515    JAW07911.1    GDKW01000893    JAI55702.1    GBBI01003031    JAC15681.1    DS235206    EEB13316.1    GL446149    EFN88458.1    GL888103    EGI67422.1    GFJQ02000734    JAW06236.1    CH477315    EAT43794.1    AAAB01008960    EAA11787.2    ATLV01016947    KE525136    KFB41655.1    AXCN02000924    GFAA01004148    JAT99286.1    ADMH02002140    ETN58322.1    JH431388    AXCM01002781    GFDL01000678    JAV34367.1    GFDL01000684    JAV34361.1    GFDL01000665    JAV34380.1    GDRN01039094    JAI67207.1    GEFM01006987    GEGO01001652    JAP68809.1    JAR93752.1    AJWK01022034    APCN01000106    GGLE01005590    MBY09716.1    GACK01001108    JAA63926.1    GL732533    EFX84884.1    GDIP01038643    LRGB01000512    JAM65072.1    KZS18745.1    GDIQ01237937    GDIQ01178995    GDIQ01154755    GDIQ01151914    GDIQ01129925    GDIQ01127214    GDIQ01125566    GDIQ01110529    GDIQ01065486    GDIQ01049346    GDIQ01046403    GDIQ01031109    JAL24512.1    GDIQ01249124    JAK02601.1    GDIP01168223    JAJ55179.1    GDIQ01239483    GDIQ01157508    GDIQ01148209    GDIQ01144019    GDIQ01144018    GDIQ01128567    GDIQ01128566    GDIQ01049347    GDIQ01034399    JAK12242.1    GDIQ01249123    JAK02602.1    GDIQ01221778    GDIQ01183009    GDIQ01169452    GDIQ01168550    GDIQ01116019    GDIQ01112221    GDIQ01062490    JAL35707.1    GDIQ01252126    JAJ99598.1    GDIQ01216930    GDIQ01198345    GDIQ01114817    GDIQ01114816    GDIQ01064043    JAK34795.1    GEZM01042876    JAV79504.1    GDIQ01202194    JAK49531.1    GDIP01240532    JAI82869.1    GDIQ01252127    JAJ99597.1    GDIQ01202193    JAK49532.1    GBHO01019949    JAG23655.1    GDIP01163270    JAJ60132.1    GDIP01015069    JAM88646.1    GDIQ01169453    JAK82272.1    GDIP01221464    JAJ01938.1    GDIQ01245027    JAK06698.1    CH940647    EDW70206.2    KQ424932    KOF70223.1    KOF70224.1    KB201239    ESO98574.1    JXUM01017668    KQ560490    KXJ82138.1    GANP01006548    JAB77920.1    CH964161    EDW80029.1    KRF99210.1    UFQS01000003    UFQT01000003    SSW96770.1    SSX17157.1    CAEY01001874   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000027135    + More
UP000007266    UP000192223    UP000000311    UP000078492    UP000078541    UP000005205    UP000078542    UP000053105    UP000053825    UP000005203    UP000078540    UP000279307    UP000053097    UP000076502    UP000075809    UP000009046    UP000008237    UP000007755    UP000008820    UP000075900    UP000007062    UP000076408    UP000030765    UP000075880    UP000075901    UP000075881    UP000075885    UP000075903    UP000075882    UP000075886    UP000000673    UP000069272    UP000075884    UP000075883    UP000092461    UP000075840    UP000085678    UP000000305    UP000076858    UP000095301    UP000008792    UP000053454    UP000030746    UP000095300    UP000069940    UP000249989    UP000007798    UP000015104   

PRIDE

H9JAS6   

Pfam

PF00612   IQ        + More
PF00632   HECT

Interpro

IPR000569   HECT_dom        + More
IPR000048   IQ_motif_EF-hand-BS       
IPR035983   Hect_E3_ubiquitin_ligase       

SUPFAM

SSF56204   SSF56204       

CDD

cd00078  HECTc

ProteinModelPortal

H9JAS6   A0A2A4JSK5   A0A3S2LU36   A0A2H1VCW6   A0A194QJG8   A0A194RNQ0   + More
A0A1E1W0Y0   A0A067QF96   A0A1Y1M0V9   A0A0C9RVD4   D6WZG6   A0A1W4XID8   A0A1B6LAX7   A0A1B6DG25   E2A4W1   A0A1B6GPJ5   A0A195E7U6   A0A195FKX1   A0A158NET2   A0A151IPW0   A0A0M8ZRH7   A0A0L7RJ98   A0A146L582   A0A088AVT6   A0A195AVU4   A0A3L8DDN0   A0A026W354   A0A154PKX7   A0A0V0G7J2   A0A151XIH1   A0A224XIP5   A0A0P4W2A9   A0A023F3A6   E0VIW0   E2B797   F4WED5   A0A1Z5LFR7   Q17BV9   A0A1S4F8R5   A0A182RUZ5   Q7Q6E5   A0A182Y2X1   A0A084VUL1   A0A182IR09   A0A182SW83   A0A182KDQ3   A0A182PPA2   A0A182VKY6   A0A182KPU4   A0A182QS02   A0A1E1XJI9   W5J243   A0A182FE37   A0A182NMG8   A0A1W4X7R7   T1IRU6   A0A182MTR3   A0A1Q3G3I3   A0A1Q3G3J5   A0A1Q3G3K2   A0A0P4WEM7   A0A131XP35   A0A1B0GJP7   A0A182I226   A0A2R5LJN6   A0A2R2MLY1   L7MI96   E9G670   A0A0P5ZVZ2   A0A0P5PK82   A0A0P5G0S3   A0A0P5CXQ5   A0A0N8AV97   A0A0N8ARU2   A0A0N8C4D0   A0A0P5G8L6   A0A0P5K155   A0A1Y1M0Y6   A0A0P5J799   A0A0P4XJ66   A0A0P5FQ36   A0A0P5JIU3   A0A0A9Y2C9   A0A0P5D3P8   A0A0P6BGA4   A0A0P5MC68   A0A0P4YZ98   A0A0N8ATA4   A0A1I8MU84   B4LEU9   A0A0L8FZX9   A0A0L8G078   V4C9W7   A0A1I8PQI6   A0A182GT51   V5H4K6   B4N6P0   A0A0Q9WSI9   A0A336K722   T1K8E1  

PDB

5XMC     E-value=1.29567e-49,     Score=500

KEGG

101743894    K10588 ubiquitin-protein ligase E3 B [EC:2.3.2.26] | (RefSeq) ubiquitin-protein ligase E3B

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0004842   GO:0016740   GO:0016874   GO:0061631   GO:0000209   GO:0006511   GO:0005515   GO:0004672   GO:0006468   GO:0005524   GO:0031683   GO:0001664   GO:0005525   GO:0007264   GO:0003824  

Length:

1078

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.817429999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02096

outside

1  -  1078

 

 

Pi

261.451685

Theta

158.431967

Tajima's D

1.883217

CLR

0.515755

CSRT

0.862706864656767

Interpretation

Uncertain