Gene

KWMTBOMO05490  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006715

Annotation

carboxypeptidase_[Bombyx_mori]

Location

Bomo_Chr10(+):3455537-3459067      View in EpiBrowser

Full name

Zinc carboxypeptidase      

Location in the cell

Extracellular   Reliability : 1.506 PlasmaMembrane   Reliability : 1.497

CDS

ATGTTTCGAAATTCATCGCGTATCCATTTTTTTATACTTCCAGGTATCCACGCACGCGAATGGATCACTCCGGCTACAACCACCTATTTCATAAACCAGTTATTGACGAGTTTGGACCCGAACATCACAGCACTGAGAGATCAATTCGACTGGCGTATTTTCCCCACCGTCAATCCTGATGGCTACCACTACAGTATTAATTACGACAGAATGTGGAGAAAAACGAGATCGAAATCTTCTTCGACTTGCCGTGGAGCCGACCCGAATCGTAATTGGGACTACAATTGGCTAAAACACGGAGCAAGCAGCAACCCTTGCGACTACCAGACTTACGGTGGCTCGCGTCCTTTCTCAGAGGTCGAAACCAGAACACTCTCCCAGTACATATCTAGTATTGAGAACTTGATGGCCTATGTCGCTTTCCATTCAGACGCGCAGATGCTTCTGCTTCCTTACTCCGATTCAACAGAACACAATGATAATTACGATGATCTGGTGACAATTGGGAAAACTTCTTTGAACTACGGTTACGCTGTCAACGGTGCAAAGTATAAAGGGCCGGCAACAGCAGCTGAAATATTGTATAAAGCGTCTGGAGGCAGCATGGATTGGGTACGGCATACTCTAGGAACTCCTATAGTTTACACATACGAACTCAGAGGCACGTACTTCTACTGGCCTCCTGAAAGGATTTCTGAACAGGGAGACGAAGTTACGCAGATGATCCTCGGCTTAGTACAGGAAGCAAGAAACTTGGGATATGTATAA

Protein

MFRNSSRIHFFILPGIHAREWITPATTTYFINQLLTSLDPNITALRDQFDWRIFPTVNPDGYHYSINYDRMWRKTRSKSSSTCRGADPNRNWDYNWLKHGASSNPCDYQTYGGSRPFSEVETRTLSQYISSIENLMAYVAFHSDAQMLLLPYSDSTEHNDNYDDLVTIGKTSLNYGYAVNGAKYKGPATAAEILYKASGGSMDWVRHTLGTPIVYTYELRGTYFYWPPERISEQGDEVTQMILGLVQEARNLGYV

Cofactor

Zn(2+)

Subunit

Heterodimer of an alpha and a beta subunit.

Similarity

Belongs to the integrin alpha chain family.
Belongs to the peptidase M14 family.

Keywords

Carboxypeptidase   Disulfide bond   Hydrolase   Metal-binding   Metalloprotease   Protease   Secreted   Zinc  

Feature

chain  Zinc carboxypeptidase

Uniprot

A0FDQ4   H9JB20   A0A3S2LUS1   A0A2A4JPY8   A0A2H1WIR8   A0A194RNZ7   + More
A0A194QI28   K7IQY4   A0A232F435   E9INB0   F4WMS6   Q5TPZ3   A0A182UYU3   A0A182QAV5   A0A154PJT5   A0A182LT40   A0A195FPR9   A0A195BNW8   V9QNN0   F4WJ50   A0A158NTV3   A0A310SCR6   W5JK64   K7IN13   A0A0J7KVA1   A0A158NQ44   A0A182P9F0   A0A195CUQ5   A0A0C9RFV3   A0A182TPH8   A0A182JEM2   A0A182K4R6   A0A0N0BEG8   A0A182LPL5   A0A2C9GQU4   A0A1I8JW39   A0A084VIH2   A0A182FUU7   A0A154PKT4   A0A182MXY6   A0A023ER77   A0A023EUA5   A0A3G5BIF5   A0A023ER66   Q9U9K2   Q16RZ2   A0A023ERV8   A0A023ESX5   A0A182G3W8   A0A023ET69   A0A023ES17   A0A182YDB7   Q6J6D4   A0A1L8DR93   A0A182QY48   A0A2A3E2U1   A0A1B0DP13   A0A1L8DQV7   A0A2P8YM67   K7IY61   A0A023ERX4   A0A182RFC6   A0A182WF36   A0A232EGG7   A0A088A4S2   A0A023ERY1   A0A023ES11   A0A2P8YM65   A0A151WLL6   Q16RZ5   A0A195FPB2   A0A1S4FRR6   B0WS12   A0A182G3X1   A0A195CTS9   A0A1Q3FMY2   W5JN76   A0A182TX13   B0WX49   A0A026WMA6   A0A195BHV6   Q7Q316   A0A182V379   B0WX47   V9QNS4   A0A084VBY4   U5EWN0   A0A195CTW9   A0A2C9GR29   A0A1I8JW63   A0A182LPK9   A0A151J021   P42788   A0A232F7M7   A0A310SEP0   A0A0L7R9B9   B0WX48   A0A182J874   A0A182TM92   A0A182VNT5  

EC Number

3.4.17.-

Pubmed

19121390    26354079    20075255    28648823    21282665    21719571    + More
12364791    14747013    17210077    24438588    21347285    20920257    23761445    20966253    24945155    30400621    10672069    17510324    26483478    25244985    29403074    24508170    30249741    8269093   

EMBL

DQ985594    ABJ97184.1    BABH01008469    BABH01008470    BABH01008471    BABH01008472    + More
RSAL01000201    RVE44448.1    NWSH01000931    PCG73503.1    ODYU01008945    SOQ52970.1    KQ459984    KPJ19045.1    KQ458793    KPJ05054.1    NNAY01001025    OXU25435.1    GL764292    EFZ17948.1    GL888218    EGI64553.1    AAAB01008966    EAL39491.3    AXCN02002112    KQ434938    KZC12083.1    AXCM01005733    KQ981382    KYN42302.1    KQ976435    KYM87054.1    ATLV01013356    KF707629    KE524854    AHC32031.1    KFB37767.1    GL888181    EGI65820.1    ADTU01026166    KQ769940    OAD52756.1    ADMH02000883    ETN64767.1    LBMM01002732    KMQ94422.1    ADTU01022957    KQ977279    KYN04252.1    GBYB01012027    JAG81794.1    KQ435828    KOX71862.1    APCN01001947    KFB37766.1    KZC12084.1    GAPW01001933    JAC11665.1    GAPW01001589    JAC12009.1    MK075163    AYV99566.1    GAPW01001948    JAC11650.1    AF165923    AY590487    AAD47827.1    AAT36725.1    CH477692    EAT37217.1    GAPW01001636    JAC11962.1    GAPW01001692    JAC11906.1    JXUM01041428    KQ561282    KXJ79110.1    GAPW01001587    JAC12011.1    GAPW01001586    JAC12012.1    AY590493    AAT36731.1    GFDF01005229    JAV08855.1    KZ288417    PBC26020.1    AJVK01017975    GFDF01005228    JAV08856.1    PYGN01000496    PSN45347.1    GAPW01001626    JAC11972.1    NNAY01004759    OXU17455.1    GAPW01001625    JAC11973.1    GAPW01001588    JAC12010.1    PSN45348.1    KQ982959    KYQ48754.1    EAT37214.1    KYN42152.1    DS232063    EDS33630.1    JXUM01041430    KXJ79113.1    KYN04096.1    GFDL01006212    JAV28833.1    ETN64768.1    DS232158    EDS36310.1    KK107167    QOIP01000010    EZA56244.1    RLU17286.1    KQ976464    KYM84415.1    EAA13019.4    EDS36308.1    KF707632    AHC32034.1    ATLV01009870    KE524552    KFB35478.1    GANO01002887    JAB56984.1    KYN04105.1    KQ980658    KYN14778.1    L08481    NNAY01000796    OXU26459.1    OAD52755.1    KQ414627    KOC67443.1    EDS36309.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053240    UP000053268    UP000002358    + More
UP000215335    UP000007755    UP000007062    UP000075903    UP000075886    UP000076502    UP000075883    UP000078541    UP000078540    UP000030765    UP000005205    UP000000673    UP000036403    UP000075885    UP000078542    UP000075902    UP000075880    UP000075881    UP000053105    UP000075882    UP000075840    UP000076407    UP000069272    UP000075884    UP000008820    UP000069940    UP000249989    UP000076408    UP000242457    UP000092462    UP000245037    UP000075900    UP000075920    UP000005203    UP000075809    UP000002320    UP000053097    UP000279307    UP000078492    UP000053825   

PRIDE

A0FDQ4    H9JB20    A0A088A4S2   

Pfam

PF00246   Peptidase_M14        + More
PF01839   FG-GAP
PF02244   Propep_M14

Interpro

IPR034223   IGCP-like_CPD        + More
IPR000834   Peptidase_M14       
IPR013517   FG-GAP       
IPR013519   Int_alpha_beta-p       
IPR028994   Integrin_alpha_N       
IPR000413   Integrin_alpha       
IPR032695   Integrin_dom_sf       
IPR003146   M14A_act_pep       
IPR036990   M14A-like_propep       

SUPFAM

SSF69179   SSF69179       

Gene 3D

2.130.10.130     3.30.70.340    

CDD

cd03860  M14_CP_A-B_like

ProteinModelPortal

A0FDQ4   H9JB20   A0A3S2LUS1   A0A2A4JPY8   A0A2H1WIR8   A0A194RNZ7   + More
A0A194QI28   K7IQY4   A0A232F435   E9INB0   F4WMS6   Q5TPZ3   A0A182UYU3   A0A182QAV5   A0A154PJT5   A0A182LT40   A0A195FPR9   A0A195BNW8   V9QNN0   F4WJ50   A0A158NTV3   A0A310SCR6   W5JK64   K7IN13   A0A0J7KVA1   A0A158NQ44   A0A182P9F0   A0A195CUQ5   A0A0C9RFV3   A0A182TPH8   A0A182JEM2   A0A182K4R6   A0A0N0BEG8   A0A182LPL5   A0A2C9GQU4   A0A1I8JW39   A0A084VIH2   A0A182FUU7   A0A154PKT4   A0A182MXY6   A0A023ER77   A0A023EUA5   A0A3G5BIF5   A0A023ER66   Q9U9K2   Q16RZ2   A0A023ERV8   A0A023ESX5   A0A182G3W8   A0A023ET69   A0A023ES17   A0A182YDB7   Q6J6D4   A0A1L8DR93   A0A182QY48   A0A2A3E2U1   A0A1B0DP13   A0A1L8DQV7   A0A2P8YM67   K7IY61   A0A023ERX4   A0A182RFC6   A0A182WF36   A0A232EGG7   A0A088A4S2   A0A023ERY1   A0A023ES11   A0A2P8YM65   A0A151WLL6   Q16RZ5   A0A195FPB2   A0A1S4FRR6   B0WS12   A0A182G3X1   A0A195CTS9   A0A1Q3FMY2   W5JN76   A0A182TX13   B0WX49   A0A026WMA6   A0A195BHV6   Q7Q316   A0A182V379   B0WX47   V9QNS4   A0A084VBY4   U5EWN0   A0A195CTW9   A0A2C9GR29   A0A1I8JW63   A0A182LPK9   A0A151J021   P42788   A0A232F7M7   A0A310SEP0   A0A0L7R9B9   B0WX48   A0A182J874   A0A182TM92   A0A182VNT5  

PDB

1AYE     E-value=1.77223e-36,     Score=380

KEGG

778503    no KO assigned | (RefSeq) carboxypeptidase

GO

GO:0008270   GO:0004181   GO:0016021   GO:0007229   GO:0008305   GO:0007155   GO:0005615   GO:0006508   GO:0005576   GO:0007186   GO:0019001   GO:0031683   GO:0001664   GO:0005525   GO:0007264   GO:0003824  

Subcellular location

Membrane  
Secreted  

Length:

255

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0356900000000001

Exp number, first 60 AAs:

0.03022

Total prob of N-in:

0.05385

outside

1  -  255

 

 

Pi

179.223004

Theta

129.281638

Tajima's D

0.424487

CLR

0.015253

CSRT

0.488375581220939

Interpretation

Uncertain