Gene

KWMTBOMO05482

Pre Gene Modal

BGIBMGA006711

Annotation

RNA_binding_motif_protein_18_[Bombyx_mori]

Location

Bomo_Chr10(+):3099091-3103044      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 2.384

CDS

ATGCTGTTCCATCGTAGCGGACCTGCAGCCGGACAGCCGAGAGGGTTTGCGTTTGTTACATACAAATTGAAACAAGATGCTGTTAAGGCAATGAACTCATTGAATGGACAGTTACTAGGCTGCAAAAGGATATGTGTCAAATTTGCTAAACACACTGCTGATGATCAAGATAAACCAAAACCAGAGCTAGGTATACCGGCGTTGGCTGGTGCAAAACCAGAGTTTAAACTCAGCAAAAAGACAGCCATCCAATCCATAGAGGCTAAACTCAAGATGATGGAGAATATGAACCCCGGTGATGACTTTGTGATCAATAAATTAGCCGCTAATGAGACTCCAATAATAACACAATACCAGAATAAAGCCCTGCAACCTCCAAATAAAACGGTCAGCTCGTTTCGAAGACGACACCCATATCATAAGAAGAGATAA

Protein

MLFHRSGPAAGQPRGFAFVTYKLKQDAVKAMNSLNGQLLGCKRICVKFAKHTADDQDKPKPELGIPALAGAKPEFKLSKKTAIQSIEAKLKMMENMNPGDDFVINKLAANETPIITQYQNKALQPPNKTVSSFRRRHPYHKKR

Description

Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.

Catalytic Activity

ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)

Cofactor

Zn(2+)

Subunit

Monomer.

Similarity

Belongs to the class-II aminoacyl-tRNA synthetase family.

Uniprot

H9JB16   Q2F5W6   A0A194RNG6   A0A194QHR1   A0A1E1WKW3   A0A1E1WJL6   + More
S4PRD3   A0A212FEV5   A0A2A4JS58   A0A2H1WZW1   A0A0L7LGG7   A0A0L7K291   A0A0T6AUL8   A0A2M4AZD2   Q17PN9   A0A182YC60   T1E7I3   A0A2M3ZJV8   A0A2P8YV48   W5JSH4   A0A2M4C1W7   A0A1S4EVE5   A0A182T9G5   A0A182FC05   A0A182ILN6   A0A182GXK2   A0A023EG31   A0A182P1J2   F4WWX8   A0A195BX75   A0A158NCU0   A0A151IGB6   A0A182K229   A0A195FA25   A0A026VXC2   A0A1Q3F2L8   A0A084WM75   A0A1Y1M0G2   A0A182QEV8   A0A182M1X5   A0A1Y1LZ88   A0A182X029   A0A182VNS5   A0A182TUB4   A0A182HPP8   A0A182KT45   D6WEB1   A0A182R1X7   Q7PZX8   A0A182MXE5   V5GDR9   A0A0M8ZV40   E2A1R3   K7IQR2   A0A232EWI2   E2BBX8   A0A2M4C130   B0X6E4   A0A1L8DFS9   A0A1W4WMF3   A0A1B6D2B8   A0A0L7RG47   A0A1B6E526   A0A0L0C4W0   A0A0J7NVV1   A0A087ZV92   A0A1A9ZLP3   A0A1A9UUZ8   A0A1A9XYC1   A0A1I8NQV8   A0A0P8XKY1   A0A1I8NQV7   U5EPC3   Q8SY84   A0A1W4VHX9   A0A0R1EA46   Q8MZG3   A0A0M4ENV8   B3MVT8   A0A0Q5TKG8   A0A151WS45   A0A1W4VV75   Q9VY29   B4Q2T9   B3NUZ9   X2JBU2   B4IGE2   B4L7I7   A0A1I8N4H5   A0A0R3P0C2   B4R4U6   A0A0R1EAT9   A0A182WD72   A0A1I8N4H4   B4JL44  

Pubmed

19121390    26354079    23622113    22118469    26227816    17510324    + More
25244985    29403074    20920257    23761445    26483478    24945155    21719571    21347285    24508170    30249741    24438588    28004739    20966253    18362917    19820115    12364791    20798317    20075255    28648823    26108605    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    18057021    25315136    15632085   

EMBL

BABH01008444    DQ311307    ABD36251.1    KQ459984    KPJ19052.1    KQ458793    + More
KPJ05047.1    GDQN01003507    JAT87547.1    GDQN01003860    JAT87194.1    GAIX01000900    JAA91660.1    AGBW02008896    OWR52279.1    NWSH01000782    PCG74239.1    PCG74240.1    ODYU01012326    SOQ58581.1    JTDY01001178    KOB74638.1    JTDY01018983    KOB51803.1    LJIG01022813    KRT78587.1    GGFK01012816    MBW46137.1    CH477190    EAT48712.1    GAMD01003022    JAA98568.1    GGFM01008041    MBW28792.1    PYGN01000343    PSN48105.1    ADMH02000597    ETN65709.1    GGFJ01010134    MBW59275.1    JXUM01020614    KQ560576    KXJ81841.1    GAPW01005296    JAC08302.1    GL888417    EGI61221.1    KQ976396    KYM92895.1    ADTU01011819    ADTU01011820    KQ977728    KYN00266.1    KQ981727    KYN37062.1    KK107648    QOIP01000008    EZA48315.1    RLU19554.1    GFDL01013254    JAV21791.1    ATLV01024391    KE525351    KFB51319.1    GEZM01043736    JAV78871.1    AXCN02001698    AXCM01002803    GEZM01043735    JAV78873.1    APCN01003267    KQ971326    EFA00855.2    AAAB01008986    EAA00474.3    GALX01006317    JAB62149.1    KQ435830    KOX71750.1    GL435766    EFN72736.1    NNAY01001854    OXU22717.1    GL447175    EFN86802.1    GGFJ01009843    MBW58984.1    DS232412    EDS41427.1    GFDF01008849    JAV05235.1    GEDC01017593    JAS19705.1    KQ414598    KOC69820.1    GEDC01004265    JAS33033.1    JRES01000902    KNC27398.1    LBMM01001317    KMQ96520.1    CH902625    KPU75423.1    GANO01003743    JAB56128.1    AY071717    AE014298    AAL49339.1    AAN09338.1    AAO41654.1    CM000162    KRK06294.1    AY113193    AAM29198.1    CP012528    ALC49796.1    EDV35083.2    CH954180    KQS30342.1    KQS30343.1    KQ982796    KYQ50611.1    AAF48376.5    EDX01683.2    EDV47097.2    AHN59710.1    CH480835    EDW48876.1    CH933813    EDW10981.1    CH379064    KRT06620.1    CM000366    EDX17903.1    KRK06293.1    CH916370    EDW00297.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000037510    + More
UP000008820    UP000076408    UP000245037    UP000000673    UP000075901    UP000069272    UP000075880    UP000069940    UP000249989    UP000075885    UP000007755    UP000078540    UP000005205    UP000078542    UP000075881    UP000078541    UP000053097    UP000279307    UP000030765    UP000075886    UP000075883    UP000076407    UP000075903    UP000075902    UP000075840    UP000075882    UP000007266    UP000075900    UP000007062    UP000075884    UP000053105    UP000000311    UP000002358    UP000215335    UP000008237    UP000002320    UP000192223    UP000053825    UP000037069    UP000036403    UP000005203    UP000092445    UP000078200    UP000092443    UP000095300    UP000007801    UP000000803    UP000192221    UP000002282    UP000092553    UP000008711    UP000075809    UP000001292    UP000009192    UP000095301    UP000001819    UP000000304    UP000075920    UP000001070   

PRIDE

H9JB16    Q2F5W6    Q8SY84    Q8MZG3    Q9VY29   

Pfam

PF00076   RRM_1        + More
PF07973   tRNA_SAD
PF02272   DHHA1
PF01411   tRNA-synt_2c

Interpro

IPR035979   RBD_domain_sf        + More
IPR000504   RRM_dom       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR039157   RBM18_RRM       
IPR018163   Thr/Ala-tRNA-synth_IIc_edit       
IPR009000   Transl_B-barrel_sf       
IPR018162   Ala-tRNA-ligase_IIc_anticod-bd       
IPR012947   tRNA_SAD       
IPR018164   Ala-tRNA-synth_IIc_N       
IPR003156   DHHA1_dom       
IPR023033   Ala_tRNA_ligase_euk/bac       
IPR002318   Ala-tRNA-lgiase_IIc       
IPR018165   Ala-tRNA-synth_IIc_core       

SUPFAM

SSF54928   SSF54928        + More
SSF101353   SSF101353       
SSF50447   SSF50447       
SSF55186   SSF55186       

Gene 3D

3.30.70.330    

CDD

cd12355  RRM_RBM18

ProteinModelPortal

H9JB16   Q2F5W6   A0A194RNG6   A0A194QHR1   A0A1E1WKW3   A0A1E1WJL6   + More
S4PRD3   A0A212FEV5   A0A2A4JS58   A0A2H1WZW1   A0A0L7LGG7   A0A0L7K291   A0A0T6AUL8   A0A2M4AZD2   Q17PN9   A0A182YC60   T1E7I3   A0A2M3ZJV8   A0A2P8YV48   W5JSH4   A0A2M4C1W7   A0A1S4EVE5   A0A182T9G5   A0A182FC05   A0A182ILN6   A0A182GXK2   A0A023EG31   A0A182P1J2   F4WWX8   A0A195BX75   A0A158NCU0   A0A151IGB6   A0A182K229   A0A195FA25   A0A026VXC2   A0A1Q3F2L8   A0A084WM75   A0A1Y1M0G2   A0A182QEV8   A0A182M1X5   A0A1Y1LZ88   A0A182X029   A0A182VNS5   A0A182TUB4   A0A182HPP8   A0A182KT45   D6WEB1   A0A182R1X7   Q7PZX8   A0A182MXE5   V5GDR9   A0A0M8ZV40   E2A1R3   K7IQR2   A0A232EWI2   E2BBX8   A0A2M4C130   B0X6E4   A0A1L8DFS9   A0A1W4WMF3   A0A1B6D2B8   A0A0L7RG47   A0A1B6E526   A0A0L0C4W0   A0A0J7NVV1   A0A087ZV92   A0A1A9ZLP3   A0A1A9UUZ8   A0A1A9XYC1   A0A1I8NQV8   A0A0P8XKY1   A0A1I8NQV7   U5EPC3   Q8SY84   A0A1W4VHX9   A0A0R1EA46   Q8MZG3   A0A0M4ENV8   B3MVT8   A0A0Q5TKG8   A0A151WS45   A0A1W4VV75   Q9VY29   B4Q2T9   B3NUZ9   X2JBU2   B4IGE2   B4L7I7   A0A1I8N4H5   A0A0R3P0C2   B4R4U6   A0A0R1EAT9   A0A182WD72   A0A1I8N4H4   B4JL44  

PDB

5SZW     E-value=0.00763739,     Score=86

KEGG

692902    no KO assigned | (RefSeq) RNA binding motif protein 18

GO

GO:0003723   GO:0003676   GO:0016021   GO:0006419   GO:0004813   GO:0005737   GO:0000049   GO:0008270   GO:0005524   GO:0003729   GO:0000166   GO:0006807   GO:0003824   GO:0044237   GO:0016627   GO:0008152   GO:0016491  

Length:

143

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00041

Exp number, first 60 AAs:

0.00041

Total prob of N-in:

0.14184

outside

1  -  143

 

 

Pi

41.471042

Theta

166.195167

Tajima's D

-1.405761

CLR

0.006964

CSRT

0.0745962701864907

Interpretation

Uncertain