SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05465
Pre Gene Modal
BGIBMGA006636
Annotation
PREDICTED:_uncharacterized_protein_LOC101741169_isoform_X4_[Bombyx_mori]
Location
Bomo_Chr10(-):2846707-2915844      View in EpiBrowser
Location in the cell
Nuclear   Reliability : 3.329
 

Sequence

CDS
ATGATTCCTACGATAAAGACGTCGGAGCCGGTCAGCGTGGTCGGGCGCGTGCCGGCCAGCGGATGTGCCAGCGGCGACATAATGTGGCTTCTTAATGAGCCCAATCAGCCTTATGAAGATTGCGAACAACTGTTATGCTTCCGGTACTACAATGGTGAGGGCGAAGAATGCACGGCGGAGTCATCAACACTGCCGCCGCGTTTTAAAGTTGACCTCAAGAATCTCCCGAATCGACTCAAAGAGGGCATGTCCAGAAAACGAAGCGGCGACCAAGTCTCGCCCTTCTCCTATAACAATGAGAGCTTTGAGATGAACTCAGAAAGTCCTCGAGTGGAGTTCGTGGCAGGCACGAGCCACGATATCGGACACCTCAGCGAGAACGTCGATAAATGCTCAATTAGTCCTTTAGAAAATAACGGGAACAATCTCGTACAAACAAAATGTGATCCTAGTAAAACCCTAGCTAATAGTTTAAGTAAAGAATCTCAAAATATGAGTAGTGAATCTCAGAGTGCTATAGATTGTAGTAAACCAACGACGTCGGGTGTTAAAAAGAAGTGTCCGCCGCCTGTTGATACGGGGGGCGGTCAGTCCGTCAATGGAATGAAAAAGAATAAATCGAATTGTGGCTTCGAATCGCCAACCTCGCCCGGCACCGAGTACTATAAAATTTGGTCACCAAAGAATCCCTGTAAAATTATGAAGTTTGTCTATGATGCAGAAAGTGCGAACGTGCCAAGCGACGCGGAAAAGTCACCGGTTCCACCTTTACCACCGAGACAATCACATAAACCGTTGGAGAGAATGCACGCGTTATCACCTCCCCAAGTGCCTAGACATAGAAAACCCAAACGGCTGACGAAACCAGAAGATGCCTTCACATTTGAACTGATCGATACGGACGAGCAGTTTTTTACAGACAACAATATTGCTAATTCTGCGACCATGCAGGCCGATATTAATGACTTTAAGCCTGGAGAATTTTATTCAGCTAATCAGACAGCTATGTCCTCGACGACCAGTTTCTGGCGTGGAGGACCAAACGTCGCACCCCTCGCGACCCCTGAAACAGACGGCAGCTTGTGTGAGTCTACTGTTTCCTCTATGAAATTAGCCAAGATGAATGAAGAAAAGAAACTCAAGCAGACGAAAGAAATACCCGAAGAGTCACCCGGAGTTAGTATGAATAAAGTTTTATTTATAAAAGATATAGGGCCTGACAATTATATAACGACGACTTTTGTTAGAAAAGATAAAGTCTCGCCACCCACCGATGTCGTCGACGGTGTTAGCGGAGTGTTCAGTCATACAGCATCCGGAGAAAAATTGCAAAATAGTTTTCTAAATGAAATAACCAACCATACTGAATTCGAAGACGATAACAGAAATCAAATAGAAGAAAAGGAAATAGTTACAAAACGACATAAGCCGTTGACGAGGCAAAACTCTGGTAGGGCGAACACCCCAACTATGATGACCGCTTTCCTAAACTCGTCCCACATCGATGTTCCTAACAAAGAGACTGATAACAGCAGTTCGAATGCAGCGAGTTCTTGTAACTCTTCACATTCTAATTCACCCGTAGATGACGTAAACAAATCGTTCCCAAGTGTCGGAACATTGTTGATGAATCGAAAATACTCAGGCGACAGTTGTACCCCAAAACATTCTAGCTTACCTCGACACTTACTAAAGAGTCTGGGAGGGGAGGGAACCCCCAAACATTCCCCTCACAAAACTGCGGTCTCAAAAAGCAACGCTGAAAGTCCTGTGCGTCCTCACCCAAGGGTTCTAACTAGAGTGGCTGCGTTGGCTGCTTCTGCTGTACCGCAATGTCCGCCTACTCCAACACATCACGCCAGAAGACCCAGGCCCTTACCGCCCTCGGACTTACACCCGCCTCCGGTACAAAACAACGAGAGCAGACTACATGACAATTTTGAAATGGTCGAATTTACAAATGAATTAAGAACTTCGGAGATTCGATCGCCTAATCTTGAATTCGTGAATAGTAATCACTTCACGATAGTTCATGCTGGGCCACCTGAAGACGTAGTGCTTAGGCGACCACGGCTAGAAGACAATGATGACAATGACAACGCTGTTGCCTCGCCCACTCCTCTGAGACACATGGCAGGAATTAGACTCCCTTCGATTCCCGAAAGAGCTTCACGGCAAATGGCGCTAACGGGAGATTTTCCTGCTAATATGATAGGTGGTATCATTGAATGTGAAGAGCCTTTACCTCCAGGCTGGGAAGCCCGCATGGATAGCCATGGAAGAGTATTCTACATTGACCACGTAAACAGGACTACCACGTGGCAAAGACCCGGGGTCAATGGCACGACTCCTAGGTCACCTGCACCTGAAGTACAAAGAAGACAACTAGACCGAAGGTATCAGTCGATACGGCGCACGATGACCCGCACTCAGCTGTCGGAGGAGGAGCTGTCTCCTCCCCCCGCGCTGCCCGCCCTCCCCGCGGCCCCGGGCACGTCCCGCGCCGAACCGCACGCGCCTCACCCCGCCGCGGACTTCCTGGCCCGACCCGACTTCTACTCCATACTGCATATGAATCAGGAAGCATCGGTCCTTTACAACTGTAACTCAACCCTGAAGCACATGATCTCGAAGATTCGCCGGGACACGTCTTCATTTGAACGCTACCAACACAACAGGGACCTCGTGGCTCTGGTCAATATGTTCAGCGAGACCGACCGGGACCTCCCGCTGGGATGGGACACGAAACTAGACAGGAATGGCAAGGCGCCGACACCCCCTCCCAGACCTCCAGTATCGGCGGCAGACGCGCATCTACACTCCCAGCCTGAAATACCAATAGCTTACAACGATAAGGTGGTGGCGTTCCTGCGGCAGCCGAACATCATGTCCATACTGCGTGAGCGCTGCGGCGGCTGCGGCGCGGCGTTGCGCGACAAGGTCAATGCCGTGCGGCTGGACGGAGGCGCCGCGCTGGCGCGCTACCAACACGACGTGCAGCTCACCTGCATGCTCAGCCTGTTCGAGCAGGAGATCATGAGTTACGTGCCGGCTAGCGGGTGCGGGGCAGGAGCGGCAGCGGGCGCGGTAGCGACAGCGGGCTCTTCGCCGGCCGCCTCGCCCGCAGCCACGCGGAGCACCCGGGCTGCCGCACCGCAACGACGGGACTTCGAGGCCAAACTCAGAGCGTTCTACAGGAAACTAGAGAGCAAAGGATACGGCCAAGGACCCGGGAAATTAAAATTGCACATTCGAAGAGAACATCTTCTCGAAGACGCCTTCCGAAGGATAATGTCGTGTGGAAAGAAAGAACTTCAGAAGGGAAAGCTCTGTGTTATATGGGACGGCGAGGAAGGCCTGGATTACGGTGGGCCAAGTCGGGAATTCTTCTTCCTACTGTCCCGGGAACTGTTCAACCCTTATTATGGACTGTTCGAGTACTCAGCCAACGATACCTACACGGTTCACGTCTCGCCCATGTCCGCCTTCGTGGACAATCATCATGAATGGTTTCGTTTTTCGGGTCGTGTGTTGGGCCTGGCGCTGGTGCACGGGTATCTCCTGGAGGCGTGGTTCACTCGCGCCCTCTACCGCGCGCTGCTGAGGCTGCCTCCTGCGCTCGAGGATGTGGACGCGCTAGATGCACAATTCGCGGCGTCCCTGCGGTGGCTGCAGTCGGCCCGTTGCGTGTCGTCACTGGAGTTAACGTTTGCCGTGTCGGAGCGGTTGGCGGACGGGAGGGTGTTGGAGAGGGAATTGAAACCGGGAGGACGCGACGTCGCCGTCACCGAGAGGAACAAGAAGGAATATCTAGAACGAGTCGTCCGATGGAGGGTGGAGAGGGGAGTCGCGGAGCAGACCGAGTGGCTCGTGCGAGGGTTCCACGAGGTGGTGGACCCTCGGCTGGTGGCCGCGTTCGACGCCCGCGAGCTCGAGCTCGTGATAGCCGGCGCGCCCGAGCTGGACGTCGCCGACTGGAGGAACCACACGGACTACCGCGGCGGCTACCACGACGCGCACCCAGTCATACTCTGGTTCTGGCAGGCCATCGACAGGTTCACAAACGAGCAGCGGCTGAGGCTCGTGCAGTTCGTGACGGGCACGTCGTCCATCCCGTACGAAGGGTTCGCGGCGCTGCGCGGCTCGACGGGCCCGCGACGCTTCTGCGTGGAGCGCTGGGGACGCGTCGAGTCCCTGCCGCGAGCGCACACCTGCTTCAACCGCCTCGACCTGCCGCCCTACCCCACCCCGCAGCTGCTCTACGAGAAACTCCTGCTCGCCGTCGAGGAGACCAACACCTTCGGCATCGAGTAG
Protein
MIPTIKTSEPVSVVGRVPASGCASGDIMWLLNEPNQPYEDCEQLLCFRYYNGEGEECTAESSTLPPRFKVDLKNLPNRLKEGMSRKRSGDQVSPFSYNNESFEMNSESPRVEFVAGTSHDIGHLSENVDKCSISPLENNGNNLVQTKCDPSKTLANSLSKESQNMSSESQSAIDCSKPTTSGVKKKCPPPVDTGGGQSVNGMKKNKSNCGFESPTSPGTEYYKIWSPKNPCKIMKFVYDAESANVPSDAEKSPVPPLPPRQSHKPLERMHALSPPQVPRHRKPKRLTKPEDAFTFELIDTDEQFFTDNNIANSATMQADINDFKPGEFYSANQTAMSSTTSFWRGGPNVAPLATPETDGSLCESTVSSMKLAKMNEEKKLKQTKEIPEESPGVSMNKVLFIKDIGPDNYITTTFVRKDKVSPPTDVVDGVSGVFSHTASGEKLQNSFLNEITNHTEFEDDNRNQIEEKEIVTKRHKPLTRQNSGRANTPTMMTAFLNSSHIDVPNKETDNSSSNAASSCNSSHSNSPVDDVNKSFPSVGTLLMNRKYSGDSCTPKHSSLPRHLLKSLGGEGTPKHSPHKTAVSKSNAESPVRPHPRVLTRVAALAASAVPQCPPTPTHHARRPRPLPPSDLHPPPVQNNESRLHDNFEMVEFTNELRTSEIRSPNLEFVNSNHFTIVHAGPPEDVVLRRPRLEDNDDNDNAVASPTPLRHMAGIRLPSIPERASRQMALTGDFPANMIGGIIECEEPLPPGWEARMDSHGRVFYIDHVNRTTTWQRPGVNGTTPRSPAPEVQRRQLDRRYQSIRRTMTRTQLSEEELSPPPALPALPAAPGTSRAEPHAPHPAADFLARPDFYSILHMNQEASVLYNCNSTLKHMISKIRRDTSSFERYQHNRDLVALVNMFSETDRDLPLGWDTKLDRNGKAPTPPPRPPVSAADAHLHSQPEIPIAYNDKVVAFLRQPNIMSILRERCGGCGAALRDKVNAVRLDGGAALARYQHDVQLTCMLSLFEQEIMSYVPASGCGAGAAAGAVATAGSSPAASPAATRSTRAAAPQRRDFEAKLRAFYRKLESKGYGQGPGKLKLHIRREHLLEDAFRRIMSCGKKELQKGKLCVIWDGEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVHVSPMSAFVDNHHEWFRFSGRVLGLALVHGYLLEAWFTRALYRALLRLPPALEDVDALDAQFAASLRWLQSARCVSSLELTFAVSERLADGRVLERELKPGGRDVAVTERNKKEYLERVVRWRVERGVAEQTEWLVRGFHEVVDPRLVAAFDARELELVIAGAPELDVADWRNHTDYRGGYHDAHPVILWFWQAIDRFTNEQRLRLVQFVTGTSSIPYEGFAALRGSTGPRRFCVERWGRVESLPRAHTCFNRLDLPPYPTPQLLYEKLLLAVEETNTFGIE

Summary

Catalytic Activity
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
Uniprot
A0A3S2N776   A0A1C9EGE3   A0A2H1WEW4   A0A194RSM9   A0A212FEU9  
Pubmed
26354079    22118469   
EMBL
RSAL01000267    RVE43228.1    KX778609    AON96562.1    ODYU01007862    SOQ51014.1    + More
KQ459984    KPJ19071.1    AGBW02008896    OWR52262.1   
Proteomes
UP000283053    UP000053240    UP000007151   
Pfam
PF00397   WW        + More
PF18436   HECW1_helix
PF16562   HECW_N
PF00632   HECT
Interpro
IPR000569   HECT_dom        + More
IPR035983   Hect_E3_ubiquitin_ligase       
IPR032348   HECW_N       
IPR036020   WW_dom_sf       
IPR040524   HECW1_helix       
IPR001202   WW_dom       
SUPFAM
SSF51045   SSF51045        + More
SSF56204   SSF56204       
CDD
cd00078  HECTc
 cd00201  WW
ProteinModelPortal
A0A3S2N776   A0A1C9EGE3   A0A2H1WEW4   A0A194RSM9   A0A212FEU9  
PDB
4BBN     E-value=9.50608e-85,     Score=804

Ontologies

KEGG
101741169    K12168 E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26] | (RefSeq) uncharacterized LOC101741169
GO
GO:0016740   GO:0004842   GO:0016874   GO:0005515   GO:0006807   GO:0003824   GO:0044237   GO:0016627   GO:0008152   GO:0016491  

Topology

Length:
1437
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.12353
Exp number, first 60 AAs:
0.01707
Total prob of N-in:
0.00090
outside
1  -  1437
 
 

Population Genetic Test Statistics

Pi
249.414361
Theta
172.408609
Tajima's D
1.3815
CLR
0.486191
CSRT
0.759362031898405
Interpretation
Uncertain
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