Gene

KWMTBOMO05462  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA006702

Annotation

Glutamine_synthetase?_partial_[Operophtera_brumata]

Location

Bomo_Chr10(+):2835525-2836883      View in EpiBrowser

Full name

Glutamine synthetase       + More
Glutamine synthetase 1, mitochondrial      

Alternative Name

Glutamate--ammonia ligase 1

Location in the cell

Cytoplasmic   Reliability : 1.382 Extracellular   Reliability : 1.279 Mitochondrial   Reliability : 1.006

CDS

ATGTACTGCTTTAAAACATGTGCTAAAGTTTTTAGAAGTATTTTCCTATCAAAGAATTTAGTGTATAAAAATATGAAACATGTTTATTATTTAAGTACTAGCAGTATCTTTGGGCATCCAGGATCGCATGATGCGTACTACAATTACTTTTTAAATTTACCGTTTCCGAAAAATAAAATTTTTGCCACCTATGTATGGATTGATGCTAGTGGGATAAATTTACGGTCTAAAGACCGAATATTGGATAAGGAGCCTTGTGATTTAGAAATGGTGCCGAAATGGTCGTATGACGGGAGTTCAACTGGACAGTCAGATCTGAAGGATTCAGATATTACACTACTTCCCGTTGCAGTGTACAGAGATCCTTTTCGTAAGAGTCCGCATATAATAGTTTTGTGTGAAACATATTCTAGTGAAGGTTTACCGACCCCCACAAACCACAGAGTATCATCAGCTATAACCTTGAGTAAAATTTGTGACCAAGAACCATGGTTTGGTATAGAACAAGAATACACAATGTTCGATCGTGATCATTGGCCTTTGGGATGGCCAAAGCCACGAGGGTATCCAGACCAAGATTCTAAGAATTCTTACTGTGGTGTAGGTGAACATGTAGCCGGGAGAGAAATTGCTGAGTGTCATGCCAGAGCTTGTATCTATTCTGGCATGGATTACGACGGATCCAATGCAGAAGTAATGAATGGATCGTGGGAATTTCAAGTAGGACCTACATTAGGAATAAAGGCAGCTGACGATATCTGGATAGGTCGGTATCTTCTAAATCGAATAGCAGAGCATTTCGACGTTATAATTAGCTTTCATCCTAAGCCAATGGGAGATGGACATGCTGGCATAGGATGTCATCATAATTTTAGTACAAAGAAAATGCGTGCCGATCAAGGTGTCACAGAAATAAAAAGGATTTGCAAAATTTTATGCGATCAACATGAAAAAATCATTAAAAGCTATGATTTAAAAGATGGTGAAGATAACAAGAAGAGGTTGGTAGGAAAATTTGAAACATCATCATATGATTCGTGTCGTGTAGGCATTTCTGATAGAAGTGCGTCGATACGAATTCAGAAAAAAGTTATATCAGAAGGCAAAGGATACTTTGAAGATCGAAGACCTGCAGGCAACTGTGATCCGTACATGGTTTGTGGCGTAATTGCTAAAACATGTATTTGA

Protein

MYCFKTCAKVFRSIFLSKNLVYKNMKHVYYLSTSSIFGHPGSHDAYYNYFLNLPFPKNKIFATYVWIDASGINLRSKDRILDKEPCDLEMVPKWSYDGSSTGQSDLKDSDITLLPVAVYRDPFRKSPHIIVLCETYSSEGLPTPTNHRVSSAITLSKICDQEPWFGIEQEYTMFDRDHWPLGWPKPRGYPDQDSKNSYCGVGEHVAGREIAECHARACIYSGMDYDGSNAEVMNGSWEFQVGPTLGIKAADDIWIGRYLLNRIAEHFDVIISFHPKPMGDGHAGIGCHHNFSTKKMRADQGVTEIKRICKILCDQHEKIIKSYDLKDGEDNKKRLVGKFETSSYDSCRVGISDRSASIRIQKKVISEGKGYFEDRRPAGNCDPYMVCGVIAKTCI

Catalytic Activity

ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate

Subunit

Homooctamer.

Similarity

Belongs to the glutamine synthetase family.

Keywords

ATP-binding   Complete proteome   Ligase   Mitochondrion   Nucleotide-binding   Reference proteome   Transit peptide  

Feature

chain  Glutamine synthetase 1, mitochondrial

Uniprot

H9JB07   A0A1C9EGE5   A0A220K8L0   A0A2H1WD59   A0A0L7LV39   A0A2A4IZL2   + More
A0A194RP39   A0A194QHK1   A0A212FET5   B4MDB7   A0A2L1DH24   A0A0A1WJ23   A0A034WM87   A0A3B0JB12   A0A0K8WJY5   A0A0R3NRL8   B4GQR9   B3MLT4   A0A0R3NWU6   A0A0L7LUZ0   A0A0R3NRZ9   A0A194RSN3   A0A1W4UPW1   B4JD48   A0A1C9EGF3   B4N0M4   W8BHI5   B4Q5M3   B4KFN9   B4ICS0   E1JHQ1   P20477   A0A1I8PPP3   B4P1V4   A0A1L8EF02   B3N774   T1PFF2   A0A0L0CBW9   A0A1L8EFC9   A0A1L8E9I9   A0A0M5IZ31   A0A0G3VJL2   A0A1I8NGQ5   U5EXT8   A0A1A9WZX8   A0A1A9XZI6   A0A1I8PBU0   A0A1B0B922   A0A151JWT9   D3TMQ8   A0A1A9UMJ0   A0A1A9Z7S4   A0A1B0FIU3   F4WK81   V5SKI8   A0A182HEV7   Q17JX2   A0A151XJR8   H9JB08   A0A195BGP1   A0A195C1J9   O96301   A0A2M3Z0E5   A0A2M4A9P1   A0A154P8H2   T1E7S5   A0A182F2H8   W5J7A8   V9IDX6   A0A0G2QRP6   A0A2M4BQA3   A0A026W7I7   A0A2A3E9Y7   A0A088A2A8   A0A165RB61   E2ATW3   A0A0L7R3F9   E2BUV7   T1D449   A0A1W4WLS5   A0A1L8E240   A0A1B6HNA3   A0A1B6FKB6   A0A1B0D3I2   K7IR04   A0A1L8E2A9   A0A1Y1KMB3   A0A1I9WLM6   J9JML2   A0A1J1HER3   A0A0K8TNN1   A0A182QFU4   W8BUA3   A0A182WGD3   A0A182V681   A0A2H8U045   A0A182TK66   A0A182IVS5   A0A182WXN5   Q7PWF1  

EC Number

6.3.1.2

Pubmed

19121390    28630352    26227816    26354079    22118469    17994087    + More
25830018    25348373    15632085    24495485    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    1969491    12537569    17550304    25315136    26108605    20353571    21719571    26483478    17510324    9887510    11674996    20920257    23761445    24508170    20798317    24330624    20075255    28004739    27538518    26369729    12364791    14747013    17210077   

EMBL

BABH01008431    KX778609    AON96570.1    MF319714    ASJ26428.1    ODYU01007862    + More
SOQ51010.1    JTDY01000038    KOB79259.1    NWSH01004968    PCG64543.1    KQ459984    KPJ19075.1    KQ458793    KPJ05023.1    AGBW02008896    OWR52259.1    CH940661    EDW71178.1    KY681698    AVD29896.1    GBXI01015621    JAC98670.1    GAKP01002286    JAC56666.1    OUUW01000004    SPP79195.1    GDHF01001139    JAI51175.1    CH379059    KRT03707.1    CH479187    EDW39941.1    CH902620    EDV30805.1    KRT03709.1    KOB79260.1    KRT03708.1    KPJ19076.1    CH916368    EDW04292.1    AON96569.1    CH963920    EDW77637.1    GAMC01008348    JAB98207.1    CM000361    CM002910    EDX03173.1    KMY87241.1    CH933807    EDW11004.1    CH480829    EDW45346.1    AE014134    ACZ94131.1    X52760    AJ012460    AY058730    CM000157    EDW87090.1    GFDG01001509    JAV17290.1    CH954177    EDV57181.1    KA646900    AFP61529.1    JRES01000726    KNC28939.1    GFDG01001510    JAV17289.1    GFDG01003349    JAV15450.1    CP012523    ALC39761.1    KP657637    AKL78862.1    GANO01000787    JAB59084.1    JXJN01010188    KQ981622    KYN39215.1    EZ422710    ADD18986.1    CCAG010013968    GL888197    EGI65384.1    KF647646    AHB50508.1    JXUM01132749    KQ567886    KXJ69239.1    CH477230    EAT46939.1    KQ982068    KYQ60545.1    KQ976491    KYM83318.1    KQ978379    KYM94490.1    AF004351    AF395490    AF395491    AAD01201.1    AAK76447.1    GGFM01001246    MBW21997.1    GGFK01004186    MBW37507.1    KQ434844    KZC08141.1    GAMD01003393    JAA98197.1    ADMH02002031    ETN59861.1    JR039080    AEY58519.1    KC344400    AGY46258.1    GGFJ01006012    MBW55153.1    KK107374    EZA51576.1    KZ288311    PBC28530.1    KR028426    AML23852.1    GL442742    EFN63125.1    KQ414663    KOC65354.1    GL450772    EFN80494.1    GALA01001103    JAA93749.1    GFDF01001281    JAV12803.1    GECU01031548    JAS76158.1    GECZ01019121    JAS50648.1    AJVK01010982    AJVK01010983    GFDF01001280    JAV12804.1    GEZM01081263    GEZM01081262    JAV61728.1    KU932410    APA34046.1    ABLF02031791    CVRI01000001    CRK86464.1    GDAI01001629    JAI15974.1    AXCN02000676    GAMC01006052    JAC00504.1    GFXV01007809    GFXV01008140    MBW19614.1    MBW19945.1    AAAB01008984    EAA14864.2   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053240    UP000053268    UP000007151    + More
UP000008792    UP000268350    UP000001819    UP000008744    UP000007801    UP000192221    UP000001070    UP000007798    UP000000304    UP000009192    UP000001292    UP000000803    UP000095300    UP000002282    UP000008711    UP000095301    UP000037069    UP000092553    UP000091820    UP000092443    UP000092460    UP000078541    UP000078200    UP000092445    UP000092444    UP000007755    UP000069940    UP000249989    UP000008820    UP000075809    UP000078540    UP000078542    UP000076502    UP000069272    UP000000673    UP000053097    UP000242457    UP000005203    UP000000311    UP000053825    UP000008237    UP000192223    UP000092462    UP000002358    UP000007819    UP000183832    UP000075886    UP000075920    UP000075903    UP000075902    UP000075880    UP000076407    UP000007062   

PRIDE

H9JB07    E1JHQ1    P20477    H9JB08   

Pfam

PF00120   Gln-synt_C        + More
PF03951   Gln-synt_N
PF03874   RNA_pol_Rpb4

Interpro

IPR008147   Gln_synt_b-grasp        + More
IPR014746   Gln_synth/guanido_kin_cat_dom       
IPR027302   Gln_synth_N_conserv_site       
IPR036651   Gln_synt_N       
IPR008146   Gln_synth_cat_dom       
IPR027303   Gln_synth_gly_rich_site       
IPR005574   RPB4/RPC9       
IPR010997   HRDC-like_sf       
IPR038324   Rpb4/RPC9_sf       
IPR036282   Glutathione-S-Trfase_C_sf       
IPR006590   RNA_pol_Rpb4/RPC9_core       

SUPFAM

SSF54368   SSF54368        + More
SSF55931   SSF55931       
SSF47819   SSF47819       
SSF47616   SSF47616       

Gene 3D

3.10.20.70     1.20.1250.40    

ProteinModelPortal

H9JB07   A0A1C9EGE5   A0A220K8L0   A0A2H1WD59   A0A0L7LV39   A0A2A4IZL2   + More
A0A194RP39   A0A194QHK1   A0A212FET5   B4MDB7   A0A2L1DH24   A0A0A1WJ23   A0A034WM87   A0A3B0JB12   A0A0K8WJY5   A0A0R3NRL8   B4GQR9   B3MLT4   A0A0R3NWU6   A0A0L7LUZ0   A0A0R3NRZ9   A0A194RSN3   A0A1W4UPW1   B4JD48   A0A1C9EGF3   B4N0M4   W8BHI5   B4Q5M3   B4KFN9   B4ICS0   E1JHQ1   P20477   A0A1I8PPP3   B4P1V4   A0A1L8EF02   B3N774   T1PFF2   A0A0L0CBW9   A0A1L8EFC9   A0A1L8E9I9   A0A0M5IZ31   A0A0G3VJL2   A0A1I8NGQ5   U5EXT8   A0A1A9WZX8   A0A1A9XZI6   A0A1I8PBU0   A0A1B0B922   A0A151JWT9   D3TMQ8   A0A1A9UMJ0   A0A1A9Z7S4   A0A1B0FIU3   F4WK81   V5SKI8   A0A182HEV7   Q17JX2   A0A151XJR8   H9JB08   A0A195BGP1   A0A195C1J9   O96301   A0A2M3Z0E5   A0A2M4A9P1   A0A154P8H2   T1E7S5   A0A182F2H8   W5J7A8   V9IDX6   A0A0G2QRP6   A0A2M4BQA3   A0A026W7I7   A0A2A3E9Y7   A0A088A2A8   A0A165RB61   E2ATW3   A0A0L7R3F9   E2BUV7   T1D449   A0A1W4WLS5   A0A1L8E240   A0A1B6HNA3   A0A1B6FKB6   A0A1B0D3I2   K7IR04   A0A1L8E2A9   A0A1Y1KMB3   A0A1I9WLM6   J9JML2   A0A1J1HER3   A0A0K8TNN1   A0A182QFU4   W8BUA3   A0A182WGD3   A0A182V681   A0A2H8U045   A0A182TK66   A0A182IVS5   A0A182WXN5   Q7PWF1  

PDB

2QC8     E-value=8.05328e-92,     Score=860

KEGG

101741588    K01915 glutamine synthetase [EC:6.3.1.2] | (RefSeq) glutamine synthetase 1, mitochondrial-like

PATHWAY

00220    Arginine biosynthesis - Bombyx mori (domestic silkworm)
00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
00910    Nitrogen metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0006542   GO:0004356   GO:0005739   GO:0007005   GO:0005524   GO:0006909   GO:0016021   GO:0000166   GO:0006352   GO:0030880   GO:0006541   GO:0006807   GO:0003824   GO:0044237   GO:0016627   GO:0008152   GO:0016491  

Subcellular location

Mitochondrion  

Length:

395

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.963739999999998

Exp number, first 60 AAs:

0.94759

Total prob of N-in:

0.08009

outside

1  -  395

 

 

Pi

142.667628

Theta

138.629871

Tajima's D

0.190616

CLR

0.011539

CSRT

0.424278786060697

Interpretation

Uncertain