Gene

KWMTBOMO05459

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr10(+):2720655-2721960      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 2.277

CDS

ATGGAGCAAATAATAGAAAAGTACAAGGAGTTCAACAGACCAATATATATAGGTTTTATCGATTACGCTAAGGCATTTGATACGATCTCACATGACGCCATCTGGGAGGCACTGGACAAATGTCAGGTCCACGACAAGTACAAAAATGTCTTGAAGAACATTTACGACAAGAGCACCAGTTGTGTGAAACTAGAGAACCGAGGACCTGAAATACCTATTCTAAGAGGAGTGAGACAAGGAGACCCGCTTTCCCCGAAGATCTTTATAGCAGTGCTGCATAACATTTTTGAGGAGCTGAAATGGAAAAACGAAGGCCTTAAAATATGTAACCAATACTTGAGTCACCTCAGATTTGCAGATGATATAGTCCTCTTAGCTGATAACAGTAGAAAACTAGAAAAAATGATAAACCAACTAAATGTACAAAGTAAAAGAGTAGGCCTATTAATGAATAAAGACAAAACAAAAGTAATGACAAACAGCGTCAAACATCCAATAAAACTTGAAGGAAAAACATTAGAATTCGTAAACAAATACATATATCTAGGAAAAGAAATATCATTTGAAGACAGAAGCGAAGAAGAAGAGGTACAACGTAGAATAAATATGAGTTGGAAAAAATATTGGTCACTCAAAGAGATAATGAAAGGAGACTATCCACTCCACCTGAAGAAAACAGTTATGGATACATGCATCTTACCAACTCTCACATATGGTTGCCAATCGTGGACTTTCAACACCACCATAAAAACAAAAATGGTTAATTGCCAGAAAGCGATGGAAAGAAGCATTCTAAAAATAAAAATAAAAGATAAAGTAAGAAGTGAATTTATACGAAAAAAGACAAAATTAATTGATGTCCTAAACTTCAGTAAAAGATTAAAGTGGCGATGGGCTGGCCACGTAGCACGCTACAGTGACAAACGATGGACAATTGAAGTGACAAAATGGAAAGGGCCTAATGGGAAAAGAAGGAAAGGACGACCTATGAAACGATGGAGTGATGATATCATAGTCACCGCTGGGAAGGAGTGGATGAGGCAGGCTGGGAACAGAGAAAATTGGATTAAGCTGGAGGAGGCCTATACCCAAATAGGGGTTCCTGTCGAGGAAAATTGA

Protein

MEQIIEKYKEFNRPIYIGFIDYAKAFDTISHDAIWEALDKCQVHDKYKNVLKNIYDKSTSCVKLENRGPEIPILRGVRQGDPLSPKIFIAVLHNIFEELKWKNEGLKICNQYLSHLRFADDIVLLADNSRKLEKMINQLNVQSKRVGLLMNKDKTKVMTNSVKHPIKLEGKTLEFVNKYIYLGKEISFEDRSEEEEVQRRINMSWKKYWSLKEIMKGDYPLHLKKTVMDTCILPTLTYGCQSWTFNTTIKTKMVNCQKAMERSILKIKIKDKVRSEFIRKKTKLIDVLNFSKRLKWRWAGHVARYSDKRWTIEVTKWKGPNGKRRKGRPMKRWSDDIIVTAGKEWMRQAGNRENWIKLEEAYTQIGVPVEEN

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Uniprot

D7F177   A0A2W1B5F8   D7F178   A0A2H1WF27   A0A2H1VY30   A0A2W1BCS2   + More
D7F179   A0A2H1VS24   A0A2W1BDX2   D7F165   D7F157   A0A3S2TAR4   D7F164   D7F166   D7F176   A4KWF2   A4KWG0   D7F160   A0A2W1BZV1   A0A023EXV2   A0A2W1BLC9   A0A2W1BMB6   D7F158   D7F159   A0A3S2KX72   A0A2G8JFM9   A0A069DZM5   A0A2W1BSQ8   W4YXJ1   A0A224XSN7   A0A1E1X2U1   A0A016V6V0   A0A016UMK7   A0A016VV56   A0A016RYK0   A0A016RXU5   A0A016V7H3   A0A016SUK5   A0A3S2TRE0   A4KWF4   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A2G8KES6   A0A0R3Q573   A0A2G8K4F2   A0A016S1D2   A0A016UTS3   A0A016UWI5   W4YXJ0   A0A0B2UUK1   A0A183UCP0   A0A3P7G895   A0A016T8K4   A0A016VRS7   A0A2W5U8K4   A0A016W6P3   A0A0K0FAW8   A0A016SM07   A0A016SL25   A0A016TIA8   A0A016U3R5   A0A016W591   A0A016SSW4   A0A023GMF8   A0A016RUR3   A0A016RV73   A0A016RRX8   A0A016T805   A0A016SKW2   A0A016WEQ1   A0A016S795   A0A016WA79   A0A016VVN3   A0A016T7J7   A0A016SLV8   A0A016S5B2   A0A016THC6   A0A016UN79   A0A016V6A2   A0A016WZF0   A0A016V4K6   A0A016X056   A0A069DX96   A0A016V3W4   A0A023EWU8   W6NSV0   A0A0P4VWD0   A0A016SGC3   A0A016SX67   A0A2G5UC19   A0A016SUD1   A0A2H2JCJ4   A0A016VCK8   W6NEE1   A0A016TNH6   A0A016S527   A0A016TNL1   A0A016TNS4   A0A016TMT8  

EC Number

4.6.1.2

Pubmed

20470440    28756777    17360547    25474469    29023486    26334808    + More
28503490    25730766    27129103   

EMBL

FJ265562    ADI61830.1    KZ150317    PZC71439.1    FJ265563    ADI61831.1    + More
ODYU01008249    SOQ51673.1    ODYU01004982    SOQ45402.1    KZ150485    PZC70710.1    FJ265564    ADI61832.1    ODYU01004088    SOQ43598.1    KZ150108    PZC73382.1    FJ265550    ADI61818.1    FJ265542    ADI61810.1    RSAL01002362    RVE40503.1    FJ265549    ADI61817.1    FJ265551    ADI61819.1    FJ265561    ADI61829.1    EF113398    EF113401    ABO45231.1    EF113402    ABO45239.1    FJ265545    ADI61813.1    KZ149907    PZC78256.1    GBBI01004876    JAC13836.1    KZ149985    PZC75698.1    KZ150072    PZC74016.1    FJ265543    ADI61811.1    FJ265544    ADI61812.1    RSAL01002130    RVE40575.1    MRZV01002136    PIK34564.1    GBGD01000380    JAC88509.1    KZ149912    PZC78089.1    AAGJ04144474    GFTR01005437    JAW10989.1    GFAC01005640    JAT93548.1    JARK01001351    EYC23394.1    JARK01001370    EYC16151.1    JARK01001340    EYC31295.1    JARK01001677    EYB83167.1    EYB83168.1    EYC23395.1    JARK01001512    EYB94036.1    RSAL01000016    RVE53061.1    EF113399    EF113400    ABO45233.1    JARK01000173    EYC41342.1    JARK01000388    EYC37469.1    EYC16150.1    MRZV01000640    PIK46507.1    UZAG01000503    VDO08661.1    MRZV01000899    PIK42833.1    JARK01001655    EYB84321.1    JARK01001362    EYC18844.1    EYC18843.1    AAGJ04050748    JPKZ01003153    KHN73088.1    UYWY01019463    VDM37564.1    JARK01001462    EYB98997.1    JARK01001341    EYC30284.1    QFQQ01000179    PZR20596.1    JARK01000695    EYC35261.1    JARK01001543    EYB91354.1    EYB91355.1    JARK01001434    EYC02684.1    JARK01001396    EYC09581.1    JARK01000807    EYC34984.1    JARK01001518    EYB93419.1    GBBM01001358    JAC34060.1    JARK01001711    EYB81734.1    JARK01001700    JARK01001393    EYB82228.1    EYC10181.1    JARK01001730    EYB81048.1    JARK01001464    EYB98786.1    EYB91353.1    JARK01000347    EYC38051.1    JARK01001621    EYB86109.1    JARK01000460    EYC36749.1    EYC30828.1    JARK01001736    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    EYB91356.1    JARK01001626    EYB85833.1    JARK01001438    EYC02111.1    EYC16376.1    JARK01001353    EYC22263.1    JARK01000055    EYC44622.1    JARK01001354    EYC21942.1    EYC44623.1    GBGD01000453    JAC88436.1    EYC21941.1    GBBI01004877    JAC13835.1    CAVP010058791    CDL95187.1    GDKW01001596    JAI54999.1    JARK01001568    EYB89432.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    PDUG01000004    PIC36796.1    JARK01001513    EYB93986.1    JARK01001348    EYC25145.1    CAVP010058300    CDL94394.1    JARK01001424    EYC04315.1    JARK01001632    EYB85541.1    EYC04316.1    EYC04317.1    EYC04314.1   

Proteomes

UP000283053    UP000230750    UP000007110    UP000024635    UP000050602    UP000031036    + More
UP000050794    UP000267007    UP000035680    UP000025227    UP000230233    UP000005237   

PRIDE

D7F177    D7F178    D7F179    D7F165    D7F157    D7F164    + More
D7F166    D7F176    D7F160    D7F158    D7F159   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF01826   TIL
PF13855   LRR_8
PF10323   7TM_GPCR_Srv
PF03372   Exo_endo_phos
PF01094   ANF_receptor
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc

Interpro

IPR005135   Endo/exonuclease/phosphatase        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR000477   RT_dom       
IPR036084   Ser_inhib-like_sf       
IPR002919   TIL_dom       
IPR032675   LRR_dom_sf       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR019426   7TM_GPCR_serpentine_rcpt_Srv       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR001170   ANPR/GUC       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       

SUPFAM

SSF56219   SSF56219        + More
SSF57567   SSF57567       
SSF53822   SSF53822       
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.80.10.10     3.30.70.1230    

ProteinModelPortal

D7F177   A0A2W1B5F8   D7F178   A0A2H1WF27   A0A2H1VY30   A0A2W1BCS2   + More
D7F179   A0A2H1VS24   A0A2W1BDX2   D7F165   D7F157   A0A3S2TAR4   D7F164   D7F166   D7F176   A4KWF2   A4KWG0   D7F160   A0A2W1BZV1   A0A023EXV2   A0A2W1BLC9   A0A2W1BMB6   D7F158   D7F159   A0A3S2KX72   A0A2G8JFM9   A0A069DZM5   A0A2W1BSQ8   W4YXJ1   A0A224XSN7   A0A1E1X2U1   A0A016V6V0   A0A016UMK7   A0A016VV56   A0A016RYK0   A0A016RXU5   A0A016V7H3   A0A016SUK5   A0A3S2TRE0   A4KWF4   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A2G8KES6   A0A0R3Q573   A0A2G8K4F2   A0A016S1D2   A0A016UTS3   A0A016UWI5   W4YXJ0   A0A0B2UUK1   A0A183UCP0   A0A3P7G895   A0A016T8K4   A0A016VRS7   A0A2W5U8K4   A0A016W6P3   A0A0K0FAW8   A0A016SM07   A0A016SL25   A0A016TIA8   A0A016U3R5   A0A016W591   A0A016SSW4   A0A023GMF8   A0A016RUR3   A0A016RV73   A0A016RRX8   A0A016T805   A0A016SKW2   A0A016WEQ1   A0A016S795   A0A016WA79   A0A016VVN3   A0A016T7J7   A0A016SLV8   A0A016S5B2   A0A016THC6   A0A016UN79   A0A016V6A2   A0A016WZF0   A0A016V4K6   A0A016X056   A0A069DX96   A0A016V3W4   A0A023EWU8   W6NSV0   A0A0P4VWD0   A0A016SGC3   A0A016SX67   A0A2G5UC19   A0A016SUD1   A0A2H2JCJ4   A0A016VCK8   W6NEE1   A0A016TNH6   A0A016S527   A0A016TNL1   A0A016TNS4   A0A016TMT8  

PDB

6AR3     E-value=0.0123255,     Score=90

KEGG

105841547    no KO assigned | (RefSeq) uncharacterized LOC105841547

GO

GO:0004519   GO:0003964   GO:0016021   GO:0005524   GO:0004672   GO:0004383   GO:0035556  

Length:

372

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01539

Exp number, first 60 AAs:

0.00464

Total prob of N-in:

0.02641

outside

1  -  372

 

 

Pi

27.359647

Theta

26.574281

Tajima's D

-0.31344

CLR

45.263132

CSRT

0.286585670716464

Interpretation

Uncertain