Gene

KWMTBOMO05455

Pre Gene Modal

BGIBMGA006701

Annotation

PREDICTED:_histone_transcription_regulator_slm9_[Papilio_xuthus]

Location

Bomo_Chr10(+):2558345-2576091      View in EpiBrowser

Full name

Protein HIRA      

Location in the cell

Extracellular   Reliability : 1.535 Nuclear   Reliability : 1.395

CDS

ATGAAGCTATTAAAACCCAGTTGGGTCAATCACGATGACAAACCGATATTTTCTGTGGATATACATCCGACTGGAAAATATTTTGCGACCGGGGGACAAGGTGGATACTCGGGCAGAGTAGTTGTGTGGAACTTGAACTCGGTGCTATGTGAATCCGTAGAATTAGACCCAAATGTTCCAAAAATAATTTGCCAAATGGACAACCACCTAGCATGTGTAAATAGTGTCCGTTGGAGTAATGGGGGTAAATACCTGGCTTCTGGAGGAGATGACAAATTGATTATGGTGTGGGGTATTAGTATGGCCCCTGGAGCACCTGGAAAGCACAAAGCTGAAACCTGGAGGTGTTTGTCTACTTTAAGAGGACATGCAGGTGATGTCTTAGACCTAGCATGGTCGCCGTTAGACAAATGGCTGGCTAGCTGCAGCGTGGATAATACAATCATTATATGGAATGCTGAGAAATTTCCAGAAATGGTGTCAGTATTAAATGGTCACACTGGCTTAGTCAAGGGTGTTACATGGGATCCTGTTGGCAAATATTTGGCATCGCAATCTGATGACAAAACCCTGAGGCTATGGAAGACTACTGATTGGGCACAGGAGGCACTCATCACAAAACCATTTTATGAATGTGGGGGCACAACCCACGTTCTTCGTCTTTCCTGGTCTCCGGACGGCCAGTACGTCTTGTCAGCTCACGCGATGAATCGTGGCGGTCCCACTGCGAGGGTCGTGGAGCGAGATGGCTGGAGATGTGATAAAGATTTCGTGGGTCACAGAAAAGCTGTAACTTGTGCTCGCTTTAACAGCAACATCTTCGTGAGGGAAGGCAAGAAGTGCTGTTGTGCCGCCGTCGGGTCCCGGGACCGCGCGCTCAGCATCTGGCAGACGTCGCTGAAGAGGCCGCTGGTCGTCATACACGACCTGTTCAGTGACAGCGTCCTGGATATATCTTGGAGCTCCGATGGGCTCAGCCTTTTAGCTTGTAGTTCGGATGGAACGGTCGCTTGCCTACAGTTTACGAACAAAGAAATCGGTACACCACTCACTCTGGAGGAAAAGAACGCATTCTACGAGAAGATCTATGGTAAAGTTTTGGCGAACGAGTCCGGCGGCGATCTCTCGTCGAACTTACTGGTAGAGTGCCCGGAGATCCTGCTCGCCAGAGAGAAACAGGAAGCCAAGAAGGAAGCTGCGGCAGCTGCTAAGGAAGATTCCACGCCGAAGAGCGAGAAATCACAAAGCGCGCCACTGGCGAGGTCGTCGCCCGCGTCCCCCGGCCCGCCGCGCCCGCTGCGGCCCCTGGACCGACAGATCGAGACGCGCACGTCCGACGGGAAGAGACGCATCACGCCCGTCTTCATACCGCACTCGCAGCTCGACGCCAATGAATCCCTCGGCTCTCAGCCCGGCGGCTCGGAGAACTGTTTCAGCACATCCTCGCAAAGCAAGTCCAGGATCCGGGTGGAAGTCCGGGACGATATCGTGATACACCCGAACGTCAGCAACCACTCCATGTCCGCGCTGCAGAACAACTCTAGGACCTCAGATAACGGTCTAGACAGTCGGCTGCGCAAGCGCACGGCGTCGTCGCTGCCCGGGCCCCGCACCGACGAGCTGCTGCACAAGCGGCCGTGCCCCTCCCCCGCGCCCGCGCCCGCCGCCGCGCCGCTGCTGCCCGCGCCCGCGCTCGGCGTGGCCGGCCCCGTCGTCAGAGCTGCTGGGCCACTGAGGCTGCAGGTGGTGAACAAAGCCTGCAACACGCATTTCGGCACCCTGTCCCGGCTGCAACTCATACCCAACAACTCCGCCTCAAATGATCCCGTTTGGGAAACTTATCTAGGCTCCCCGGTGTGCTGCATCGCGTGCGACGCTCGCTGGGCGTGCGTGTCGTGCGCGGACGGCACGCTGCACGCGTGGCGCGTCTCGCGGTCGCACGCCGCGCGGGCCCTGCCGCCGCTCGCGCTGCCGGCGGCGGCGGCGCGCCTCACGCTGTGTGGGGACACGCTGGCGGCGGTGACGGTGACGGCGGAGCTGGCCATCTGGGACCTGGCCGCCGCCGCCTGCCTCGTGCGACCGCTCTGCTTCAGATCCTTGCTGACTCCTGGAGCTACGGTAACGAATTGTTCTCTACTGGAGGACGGCAACCCTTTGATCTCATTAAGCAACGGGAAGACTTACATATACAGCCAGAAACTGTGCGCCTGGTGA

Protein

MKLLKPSWVNHDDKPIFSVDIHPTGKYFATGGQGGYSGRVVVWNLNSVLCESVELDPNVPKIICQMDNHLACVNSVRWSNGGKYLASGGDDKLIMVWGISMAPGAPGKHKAETWRCLSTLRGHAGDVLDLAWSPLDKWLASCSVDNTIIIWNAEKFPEMVSVLNGHTGLVKGVTWDPVGKYLASQSDDKTLRLWKTTDWAQEALITKPFYECGGTTHVLRLSWSPDGQYVLSAHAMNRGGPTARVVERDGWRCDKDFVGHRKAVTCARFNSNIFVREGKKCCCAAVGSRDRALSIWQTSLKRPLVVIHDLFSDSVLDISWSSDGLSLLACSSDGTVACLQFTNKEIGTPLTLEEKNAFYEKIYGKVLANESGGDLSSNLLVECPEILLAREKQEAKKEAAAAAKEDSTPKSEKSQSAPLARSSPASPGPPRPLRPLDRQIETRTSDGKRRITPVFIPHSQLDANESLGSQPGGSENCFSTSSQSKSRIRVEVRDDIVIHPNVSNHSMSALQNNSRTSDNGLDSRLRKRTASSLPGPRTDELLHKRPCPSPAPAPAAAPLLPAPALGVAGPVVRAAGPLRLQVVNKACNTHFGTLSRLQLIPNNSASNDPVWETYLGSPVCCIACDARWACVSCADGTLHAWRVSRSHAARALPPLALPAAAARLTLCGDTLAAVTVTAELAIWDLAAAACLVRPLCFRSLLTPGATVTNCSLLEDGNPLISLSNGKTYIYSQKLCAW

Description

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Similarity

Belongs to the WD repeat HIR1 family.

Uniprot

H9JB06   A0A1C9EGF7   A0A194QJB6   A0A2A4IZK4   A0A2J7PX46   A0A2J7PX32   + More
A0A067RP77   A0A182VUX0   A0A182QHA6   A0A182M5Q8   A0A084VPJ5   A0A182NEH0   A0A182PA84   A0A182IV44   W5JB93   A0A182JSZ8   A0A182F570   A0A182X0F3   A0A182VNK0   A0A182RGD1   A0A026WE51   Q7QG42   A0A2M4AGS2   A0A182TP39   A0A182IE67   A0A182L5J4   A0A1Y1K5P0   A0A1Y1K0F1   A0A1Y1K3B7   A0A1Y1K0P6   A0A1Y1K0G8   E9G6A3   A0A1B6BYQ8   E2BJI9   A0A1I8MYG2   A0A1Q3EY99   A0A0C9R844   A0A182G0Q1   A0A1J1IV56   A0A158NUT4   A0A195CPH3   A0A151K133   A0A182G1C2   A0A151IRA5   A0A1I8PAL3   E2AMT4   A0A1W4XJ25   A0A2M4BCN6   A0A2M4BCP0   W8BYC3   A0A2A3E7T5   A0A0A1WMF7   A0A088AJC3   B0W5Q4   Q0IF51   A0A154PIC9   A0A1B0CV75   H3C2W1   A0A131ZDY3   A0A1Z5L8I4   A0A3B4FN31   H3DH56  

Pubmed

19121390    26354079    24845553    24438588    20920257    23761445    + More
24508170    30249741    12364791    20966253    28004739    21292972    20798317    25315136    26483478    21347285    24495485    25830018    17510324    15496914    26830274    28528879   

EMBL

BABH01008420    KX778609    AON96565.1    KQ458793    KPJ05015.1    NWSH01004602    + More
PCG64858.1    NEVH01020862    PNF20894.1    PNF20893.1    KK852507    KDR22430.1    AXCN02000858    AXCM01000440    ATLV01015007    KE524999    KFB39889.1    ADMH02001881    ETN60673.1    KK107261    QOIP01000012    EZA53951.1    RLU15788.1    AAAB01008839    EAA05842.4    GGFK01006672    MBW39993.1    APCN01004570    GEZM01096318    JAV54995.1    GEZM01096321    JAV54992.1    GEZM01096322    GEZM01096317    JAV54991.1    GEZM01096320    JAV54993.1    GEZM01096315    JAV54999.1    GL732533    EFX84898.1    GEDC01030895    GEDC01030892    JAS06403.1    JAS06406.1    GL448571    EFN84146.1    GFDL01014847    JAV20198.1    GBYB01004205    JAG73972.1    JXUM01037136    JXUM01037137    KQ561118    KXJ79650.1    CVRI01000061    CRL04139.1    ADTU01026698    KQ977481    KYN02392.1    KQ981296    KYN43106.1    JXUM01038252    KQ561158    KXJ79512.1    KQ981144    KYN09146.1    GL440896    EFN65248.1    GGFJ01001673    MBW50814.1    GGFJ01001674    MBW50815.1    GAMC01004942    GAMC01004938    JAC01614.1    KZ288338    PBC27807.1    GBXI01014250    JAD00042.1    DS231844    EDS35707.1    CH477394    EAT41888.1    KQ434899    KZC10950.1    AJWK01030162    GEDV01000106    JAP88451.1    GFJQ02003355    JAW03615.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000235965    UP000027135    UP000075920    + More
UP000075886    UP000075883    UP000030765    UP000075884    UP000075885    UP000075880    UP000000673    UP000075881    UP000069272    UP000076407    UP000075903    UP000075900    UP000053097    UP000279307    UP000007062    UP000075902    UP000075840    UP000075882    UP000000305    UP000008237    UP000095301    UP000069940    UP000249989    UP000183832    UP000005205    UP000078542    UP000078541    UP000078492    UP000095300    UP000000311    UP000192223    UP000242457    UP000005203    UP000002320    UP000008820    UP000076502    UP000092461    UP000007303    UP000261460   

PRIDE

H9JB06   

Pfam

PF00400   WD40        + More
PF07569   Hira
PF09453   HIRA_B

Interpro

IPR001680   WD40_repeat        + More
IPR017986   WD40_repeat_dom       
IPR011494   Hira       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR019015   HIRA_B_motif       
IPR036322   WD40_repeat_dom_sf       
IPR019775   WD40_repeat_CS       
IPR031120   HIR1       
IPR011044   Quino_amine_DH_bsu       
IPR020472   G-protein_beta_WD-40_rep       

SUPFAM

SSF50978   SSF50978        + More
SSF50969   SSF50969       

Gene 3D

2.130.10.10    

ProteinModelPortal

H9JB06   A0A1C9EGF7   A0A194QJB6   A0A2A4IZK4   A0A2J7PX46   A0A2J7PX32   + More
A0A067RP77   A0A182VUX0   A0A182QHA6   A0A182M5Q8   A0A084VPJ5   A0A182NEH0   A0A182PA84   A0A182IV44   W5JB93   A0A182JSZ8   A0A182F570   A0A182X0F3   A0A182VNK0   A0A182RGD1   A0A026WE51   Q7QG42   A0A2M4AGS2   A0A182TP39   A0A182IE67   A0A182L5J4   A0A1Y1K5P0   A0A1Y1K0F1   A0A1Y1K3B7   A0A1Y1K0P6   A0A1Y1K0G8   E9G6A3   A0A1B6BYQ8   E2BJI9   A0A1I8MYG2   A0A1Q3EY99   A0A0C9R844   A0A182G0Q1   A0A1J1IV56   A0A158NUT4   A0A195CPH3   A0A151K133   A0A182G1C2   A0A151IRA5   A0A1I8PAL3   E2AMT4   A0A1W4XJ25   A0A2M4BCN6   A0A2M4BCP0   W8BYC3   A0A2A3E7T5   A0A0A1WMF7   A0A088AJC3   B0W5Q4   Q0IF51   A0A154PIC9   A0A1B0CV75   H3C2W1   A0A131ZDY3   A0A1Z5L8I4   A0A3B4FN31   H3DH56  

PDB

2YMU     E-value=1.66029e-17,     Score=222

KEGG

101741022    K11293 protein HIRA/HIR1 | (RefSeq) protein HIRA homolog

GO

GO:0006351   GO:0006325   GO:0006355   GO:0005634   GO:0000417   GO:0003714   GO:0006336   GO:0031935   GO:0000070   GO:0030702   GO:0000790   GO:0000775   GO:0005515   GO:0022857   GO:0005215   GO:0050660   GO:0016627   GO:0008152   GO:0016491   GO:0003824  

PANTHER

PTHR13831  

Subcellular location

Nucleus  

Length:

737

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.1666

Exp number, first 60 AAs:

0.00023

Total prob of N-in:

0.00012

outside

1  -  737

 

 

Pi

252.723808

Theta

175.865977

Tajima's D

0.109186

CLR

16.280331

CSRT

0.393730313484326

Interpretation

Uncertain