Gene

KWMTBOMO05439

Pre Gene Modal

BGIBMGA011142

Annotation

PREDICTED:_tumor_protein_p63-regulated_gene_1-like_protein_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr10(+):2343733-2347124      View in EpiBrowser

Full name

Tumor protein p63-regulated gene 1-like protein      

Alternative Name

Mossy fiber terminal-associated vertebrate-specific presynaptic protein
Protein FAM79A

Location in the cell

Cytoplasmic   Reliability : 1.604 Nuclear   Reliability : 1.153

CDS

ATGAGCGATATTTTAGAAGATGATCTCGAGTTTCGGGGCGGTACGCTTCAACTTTCAACCGACAATTCTGCGGTAGGTGTTGTTGAAAATCAGCCCAGTGTCACGACAGATTCTACAAGAAAACAGTCCCAGGGCAATGTGCATCCTTCTGTTCTCTCCGGTGCAGATTCTTTGACATCATCTACTAATTCTTTTGCAGATGCTAGAACACAGGAACAGCAGAATGCCTCAGGATTATCTCCAACAGAGTCTCAGACGGTATACCCTCGGTATGATGTGCCATTCAATAAGGAGAATATAAAAGACTTCTTCACATTCAGAAAAGGTGTTGTAGAAGCAGCCATACAGGAATGTATTACCATTTTGCTGTTTCCGGAGGATGGAGAATACCTAGGGTCCTGGCTTTTGACAGAAATAACATTATGGGACAACGAAAAGGAGAGAATCGTACTGCTTACTTCACGACTAGTTATGACTATCAAATATGACTTTATTGCTATGAAACAGTTGGATTTTAAAAAGACTTATCTTGATGACTTAGATACTATTGTGATCGGTGAACTGGTTTATCCTCCATCTTCATTGGTACCGGAACGTAACCTGCGTGGAGTCCGTTTGATGTGGAACAAAGGTGAGCCACTGCCTCTGAAGACTGTTTGGAATCCGTTTAGTCAGGATGTACCATTTCTGACATTTGCCTCACATCCTATTTATTGGCATAAAGATGGTGGAGTAGAGGAGCGCGCCACGTACGACATGGAAACTTTTGCCCAAAAGCTACAAAGAGCTATTGAAATAATGCCTTCTTCTTCCTGTTGCATACATCACTCACCCATTGTCATACAAAGCTATGTTGGACTAACATCTATGCTCCATAATAAAACCAGTATGGGATTCTTCAAGGTCAGGGGAAAGTTTAGTTTCTAA

Protein

MSDILEDDLEFRGGTLQLSTDNSAVGVVENQPSVTTDSTRKQSQGNVHPSVLSGADSLTSSTNSFADARTQEQQNASGLSPTESQTVYPRYDVPFNKENIKDFFTFRKGVVEAAIQECITILLFPEDGEYLGSWLLTEITLWDNEKERIVLLTSRLVMTIKYDFIAMKQLDFKKTYLDDLDTIVIGELVYPPSSLVPERNLRGVRLMWNKGEPLPLKTVWNPFSQDVPFLTFASHPIYWHKDGGVEERATYDMETFAQKLQRAIEIMPSSSCCIHHSPIVIQSYVGLTSMLHNKTSMGFFKVRGKFSF

Description

Presynaptic protein involved in the synaptic transmission tuning. Regulates synaptic release probability by decreasing the calcium sensitivity of release.

Subunit

Forms homomultimers (By similarity). Multimerization appears to be important for presynaptic targeting (By similarity). Interacts with BSN (PubMed:17869247).
Forms homomultimers (PubMed:23723986). Multimerization appears to be important for presynaptic targeting (PubMed:23723986). Interacts with BSN (By similarity).
Forms homomultimers. Multimerization appears to be important for presynaptic targeting. Interacts with BSN.

Similarity

Belongs to the TPRG1 family.

Keywords

Cell junction   Complete proteome   Cytoplasmic vesicle   Membrane   Phosphoprotein   Reference proteome   Synapse   Alternative splicing  

Feature

chain  Tumor protein p63-regulated gene 1-like protein
splice variant  In isoform 2.

Uniprot

H9JNN8   A0A1E1WC65   A0A2A4JHW2   A0A2A4JIG2   A0A3S2NV30   A0A194RSP4   + More
A0A194QHI0   A0A212FES0   A0A1C9EGG2   A0A0L7LHW8   A0A069DQE3   A0A224XUW6   A0A1B6KUZ9   A0A2J7RJC2   A0A1B6CGL3   A0A0V0G824   A0A0P4VMI5   A0A1B6LVL9   A0A1B6EXS0   T1IF90   A0A1B6CE73   A0A0A9YIB9   A0A067QS48   A0A1B0CYD9   A0A1B0C9U8   A0A232FN14   A0A3L8DSU2   A0A1L8DAI0   N6UIR2   A0A1B6HS07   A0A087U5M0   A0A131XJS9   A0A1B6HV89   A0A147BRC0   L7M7D3   L7LW28   A0A2P8YK67   A0A2R5L454   A0A293M2I8   K1PH90   A0A1S3JCB8   A0A3N0YRM1   B8A4V5   Q4VBH9   B7QFB9   A0A1W4YUF5   G3U8A4   I3M9S1   H0V4I1   G3STT5   A0A3B4ELZ3   A0A3Q3DP29   W5MDF2   A0A1A6HEE1   A0A3B5AYN0   A0A3B3SVS3   A0A3Q1GSL6   A0A1U7QUB0   L8YCV3   A0A2K5W509   A0A2K6C394   F7GVM5   A0A1S3A062   A0A3P9L0F1   A0A2Y9KL17   W5UIQ6   Q9DBS2   A8WCF8   I3J198   A0A3L7I9N6   A0A3Q3G2B9   A0A0D9S8U6   W5L3I9   A0A2K5D3P9   A0A2K5L9Y0   A0A096N5L4   A0A2K5QRC9   A0A2K5JDC6   H2N9D5   H2PXV8   Q5T0D9   T1DKG9   A0A0F7Z436   A0A2K5D3L3   F7C1W0   J3SDL5   A0A3Q2G9J6   A0A226PEH5   F6RDL6   A0A3Q1C7V8   A0A3P8T855   A0A3B4FRK8   A0A3Q3BZH8  

Pubmed

19121390    26354079    22118469    26227816    26334808    27129103    + More
25401762    26823975    24845553    28648823    30249741    23537049    28049606    29652888    25576852    29403074    22992520    23594743    21993624    29240929    23385571    17431167    25319552    17554307    23127152    17869247    16141072    19468303    15489334    21183079    22673903    23723986    26212709    25186727    29704459    25329095    16136131    14702039    16710414    18669648    23758969    25243066    23025625    24621616    19892987   

EMBL

BABH01035138    GDQN01006488    JAT84566.1    NWSH01001403    PCG71366.1    PCG71364.1    + More
RSAL01000166    RVE45274.1    KQ459984    KPJ19091.1    KQ458793    KPJ05003.1    AGBW02008897    OWR52241.1    KX778609    AON96582.1    JTDY01001122    KOB74811.1    GBGD01002601    JAC86288.1    GFTR01004226    JAW12200.1    GEBQ01024695    JAT15282.1    NEVH01002994    PNF40926.1    GEDC01024823    JAS12475.1    GECL01001979    JAP04145.1    GDKW01002927    JAI53668.1    GEBQ01012245    JAT27732.1    GECZ01027158    JAS42611.1    ACPB03019847    GEDC01025623    JAS11675.1    GBHO01040153    GBHO01039546    GBHO01039544    GBHO01039543    GBHO01014344    GBHO01014343    GBHO01014341    GBHO01014340    GBHO01014339    GBHO01014338    GBHO01014336    GBHO01009565    GBRD01017987    GBRD01016833    GBRD01003044    GBRD01003033    GDHC01011629    GDHC01001564    JAG03451.1    JAG04058.1    JAG04060.1    JAG04061.1    JAG29260.1    JAG29261.1    JAG29263.1    JAG29264.1    JAG29265.1    JAG29266.1    JAG29268.1    JAG34039.1    JAG47840.1    JAQ07000.1    JAQ17065.1    KK853018    KDR12422.1    AJVK01000036    AJWK01002864    NNAY01000006    OXU32126.1    QOIP01000004    RLU23382.1    GFDF01010744    JAV03340.1    APGK01018557    KB740081    KB632133    ENN81610.1    ERL89021.1    GECU01030248    JAS77458.1    KK118303    KFM72659.1    GEFH01002635    JAP65946.1    GECU01029115    JAS78591.1    GEGO01002133    JAR93271.1    GACK01005991    JAA59043.1    GACK01009961    JAA55073.1    PYGN01000535    PSN44647.1    GGLE01000150    MBY04276.1    GFWV01008581    MAA33310.1    JH818655    EKC18254.1    RJVU01028295    ROL48852.1    BX323556    BC095797    AAH95797.1    ABJB010644350    DS924794    EEC17541.1    AGTP01101221    AAKN02028950    AHAT01009795    LZPO01034883    OBS76636.1    KB359209    ELV14253.1    AQIA01006197    JSUE03000080    JV045147    JV045148    JV045149    AFI35218.1    JT411707    AHH39567.1    AK004324    AK004777    AK155413    AL806525    BX465212    BC019544    EU220430    BC160865    AAI60865.1    ABW83994.1    AERX01012533    RAZU01000081    RLQ74829.1    AQIB01136164    AHZZ02015123    ABGA01233990    NDHI03003447    PNJ47921.1    AACZ04059708    GABD01006620    NBAG03000385    JAA26480.1    PNI31448.1    AK289919    AL513320    BC019034    GAAZ01002682    JAA95261.1    GBEX01003652    JAI10908.1    GAMS01004845    GAMS01004844    GAMR01008101    GAMQ01000116    JAB18291.1    JAB25831.1    JAB41735.1    JU176352    AFJ51875.1    AWGT02000089    OXB78124.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000053268    UP000007151    + More
UP000037510    UP000235965    UP000015103    UP000027135    UP000092462    UP000092461    UP000215335    UP000279307    UP000019118    UP000030742    UP000054359    UP000245037    UP000005408    UP000085678    UP000000437    UP000001555    UP000192224    UP000007646    UP000005215    UP000005447    UP000261440    UP000264820    UP000018468    UP000092124    UP000261400    UP000261540    UP000257200    UP000189706    UP000011518    UP000233100    UP000233120    UP000006718    UP000079721    UP000265180    UP000248482    UP000221080    UP000000589    UP000002494    UP000005207    UP000273346    UP000264800    UP000029965    UP000018467    UP000233020    UP000233060    UP000028761    UP000233040    UP000233080    UP000001595    UP000002277    UP000005640    UP000008225    UP000265020    UP000198419    UP000002281    UP000257160    UP000265080    UP000261460    UP000264840   

PRIDE

H9JNN8    Q9DBS2    A8WCF8    Q5T0D9   

Pfam

PF12456   hSac2

Interpro

IPR040242   TPRG1-like        + More
IPR034753   hSac2       
IPR022158   Inositol_phosphatase       

ProteinModelPortal

H9JNN8   A0A1E1WC65   A0A2A4JHW2   A0A2A4JIG2   A0A3S2NV30   A0A194RSP4   + More
A0A194QHI0   A0A212FES0   A0A1C9EGG2   A0A0L7LHW8   A0A069DQE3   A0A224XUW6   A0A1B6KUZ9   A0A2J7RJC2   A0A1B6CGL3   A0A0V0G824   A0A0P4VMI5   A0A1B6LVL9   A0A1B6EXS0   T1IF90   A0A1B6CE73   A0A0A9YIB9   A0A067QS48   A0A1B0CYD9   A0A1B0C9U8   A0A232FN14   A0A3L8DSU2   A0A1L8DAI0   N6UIR2   A0A1B6HS07   A0A087U5M0   A0A131XJS9   A0A1B6HV89   A0A147BRC0   L7M7D3   L7LW28   A0A2P8YK67   A0A2R5L454   A0A293M2I8   K1PH90   A0A1S3JCB8   A0A3N0YRM1   B8A4V5   Q4VBH9   B7QFB9   A0A1W4YUF5   G3U8A4   I3M9S1   H0V4I1   G3STT5   A0A3B4ELZ3   A0A3Q3DP29   W5MDF2   A0A1A6HEE1   A0A3B5AYN0   A0A3B3SVS3   A0A3Q1GSL6   A0A1U7QUB0   L8YCV3   A0A2K5W509   A0A2K6C394   F7GVM5   A0A1S3A062   A0A3P9L0F1   A0A2Y9KL17   W5UIQ6   Q9DBS2   A8WCF8   I3J198   A0A3L7I9N6   A0A3Q3G2B9   A0A0D9S8U6   W5L3I9   A0A2K5D3P9   A0A2K5L9Y0   A0A096N5L4   A0A2K5QRC9   A0A2K5JDC6   H2N9D5   H2PXV8   Q5T0D9   T1DKG9   A0A0F7Z436   A0A2K5D3L3   F7C1W0   J3SDL5   A0A3Q2G9J6   A0A226PEH5   F6RDL6   A0A3Q1C7V8   A0A3P8T855   A0A3B4FRK8   A0A3Q3BZH8  

KEGG

101742591    no KO assigned | (RefSeq) tumor protein p63-regulated gene 1-like protein

GO

GO:0005737   GO:0042802   GO:0008021   GO:0051966   GO:0030672   GO:0044305   GO:0030054   GO:0070062  

PANTHER

PTHR31108  

Subcellular location

   Localized to the active zone presynaptic nerve terminals.   With evidence from 2 publications.

Length:

308

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0385

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00818

outside

1  -  308

 

 

Pi

139.403939

Theta

141.164149

Tajima's D

0.075857

CLR

0.339152

CSRT

0.392880355982201

Interpretation

Uncertain