Gene

KWMTBOMO05428

Pre Gene Modal

BGIBMGA006686

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_13_[Bombyx_mori]

Location

Bomo_Chr10(+):1870266-1879126      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 13      

Location in the cell

Nuclear   Reliability : 1.683 PlasmaMembrane   Reliability : 1.55

CDS

ATGATAACCAACCATATTTCATGTTCTCGACATTCTGGAGTAAAGCGGTCTGCGTCTCCGGCGAGCGAGTCCCGGCCGGCCGTCGCATGCGGCGCGGGGGGCGCGGGCCGGGGCGCCGCCCGGTCGTGCCGCCCTGCCGCCCCGCCCGCGCTGACCGCCCTGCCCGCCCTGCCTGCCTCACCCGCCCTGCCGGCCTGTCCGCTGCTGGTCAACGTGCTGCTCGCTGACACCGTACTCAACGTCTTCCGGGATCATAACTTCGATAGTTGCACGGTCTGCGTCTGCAACGAAGGGACTAAGGTCATAGGTAACATCAGGGGAGCAGACGCGGCGACCTACCTGTCCGAGGGCGGAGAGGGGAGCGGCGAGGAGCCCGCCAGCTGCACGTGCGGGTTCAGCGCCATCGTCAACCGGCGACTCGCACATCGATCCGGACTCTTCTATGAGGACGAGATGGAGATCACCGGGTGTGCGGAGACCGTGAGCAGCGCGGGCGGGGCGCGGCTGGGCGACGTGACGGGCGCGGTGCTGGCCCAGCTCGGCAGCGTGCACGCCGCGCCCACCGCCCTGGCGCGCGCCGCCCGCAGCGCCGCCGCCGCGCACCACCCGCACGAGCATCTGCGACTCAACCTGCTCGAGTACTCTGATGGAGGAGCTGCTGCGGCGAAAGCGTTACGAGCGGCGGGCGGAGCCTACGCCGGCGCCGGTCCCCCGTGCAGCAACGCCCCCGTCGGTGGCTCCATTAATGAAAGTGCCCCCAGCGCCGTGCACCGCTGGCCCTTCATCGGAGCGCGGGCGCCACGCTCCTCCAGGGACGTCGTGAGATTGATGCGACGACTCCGGCCTTTGCTCCAGGATGCGATCCAGAAGCGATGTTGTGGAGCGCGCATGTGGGACGGGGTCACGGGGCCGCTGACCTGGCGCCAGTTCCACCGCCTGGCGGGCCGGAGGAACGAAGACCTGTGCGAGCCCCAGCCGGTCCCGTCGCTGCTCGTCGGACACGACCGCGACTGGATCTCGCTCAGTCCGTACGCCCTGCGCCACTGGGAGCGCCTCAGTCTCGAACCTTACGCCTACTCTCGCGACGTCGCCTACGTGGTGGTGGCCGCCGACTGCGACGCACTCGCGGACCCTCTCCGGGCCTTCTTCCGCGAGCTGTCCACGGCGTACGAGGCGTGTCGTCTCGGCAGGCACCGGCCCGTGACCCGCCTGGCCCGGGACGGCCTGGTGCGGACGGGAGCGGCGCGGTCCGGCGAGACGGACGAGTGGGCGGGCCCCCTACCGGCCGGCCGCCTCGGGCGCTACTTGCGGGCCTACAGCGAGGCGCTGCGGACCGCTCTGGTCCCGCAGCTCGCGGCCCTCAACCTGGACCGGACTCTGCTGGAGGGCGAGCGGTCCGACTCAATGCGGCCGCCCGCCACCCCCGAGCGTCCTTCTTCACCCACCGATCACGAGGCGGAGCCCGCGCCCGCTCCGCCGCCCCCTGCCGCTCCGGATGACGACGAGGCCGGTCCGCCAGCCCTCGTCCTTTACATCGTGGAACCCCCTGCCGCCACCGCCCACCGAGCCTCCGCGCTTCACGCCCTGCTGAGACTCGCCGCTAACACGTACAACCATCTCCATCACCATAACCCTCTCATTAAGATAATATCGTTGGAGAGTGTGAGCGAGCAGTGGAGCGGCGCCGGCGTGGGCGCGGGGGCGCGGGCCCTCGCCTTCACGGTGTACAGCGGCGCGCGCCGGCTGCTGCACCACCACGCCAACGGCAAGTCCTTGACCGGGTTCGGAACGGCCGCCGCCGCTAACCTCTTCCTGCAAGCCAAGGACGACAAGAACCGCGCGCCCTACCGACTGTACTCCCCCGCGTGGGTGCTGGCTGCGCCCCGAGCCCTGCGCGAAGTGGCCGAGACCTGGGGCCAAGGCGGGACCGCTGACGCCGTCCTCTTCGTGTCGTACTGCCTCTCGCACGACCAGCGCTGGTTGTTGGCGGCCGCCACCGACTCCCGCGGAGAACTGCTCGACACCATCGCGATCAACATACACGTACCTCACAGATCGAGGCGGAGACGGAGCGGCACGGCGAGGCGGCTCGGACTCACCAAGCTCATGGACTTCACGCTGGGCGTCATGAGCCAGGCCGCGCAACCCTGGAGACTCGTCATTGGACGAGTCGGTCGCATTGGACACGGCGAACTCAAAGGCTGGAGTTGGTTGTTATCGCGAAAGAACTTGGATCAAGTGTCGACTACGCTGAAAGACCTGTGCGGCAGCTGCGGCTCGGGGGCTCCGTGCGTGCTGTCGGCCTGCCTGGTGTCCACCGAGCCCGACTCGTGCCTGCGCCTCATGGCCGACCGCTTCACGCCCGACGAACGCTTCTCCCAGGCCTCCATCCAGTCGCACCTGCACACGCCGCGCGACGTCTCCGCCACGCACATCCTTGTGTTTCCCACCTCTGCCACCACGCAGTCGACTCCGATGACCTTCGAGCAGCCCCTCGCGAACGGCGAGGACGGCGACATGATGCTGCTCGACATCAACGACGAGGACGGGGAGCACATCGACGAGCTGCTCAACTGCGACATGTTCAACAACATGTGGGCGCCCGGCAGCCCGCGCCGCGCCGACGACGACGCCGCCAGCCCCACGCCGCACCTCGCGCAGCAGCGCCTGCGGGACGACGGCCGCGAGGAGCGCGTGGGCACCGTGCTGCAGCAGCCGCTCGCGCTCGGCTACACCGTGTCCACGGCGCCGCTGGCCGGCATGCCCGCCTGGTGGTGGGCGAGCTGCGCGCACCTGCGGGACGCCTGCCCCGCCTTCCTCAAGACCGCGCTGCACCTGCACTCGGTGCACGGCGCCGACGACTACGCGGCCTTCACCCAGCGCCGCGACCAGCCCGCCCACCCGCTGGACTCGCAGACCACCACGGACGTGCTGCGGTACGTGCTGGAGGGCTACAACGCGCTGTCGTGGCTGGCGCTGGACACGAGCACGCACGACCGCCTGTCCTGTCTGCCGCTGCACGTGCAGGTGCTCATGCAGCTGTACCACGCGGCGGCCGCGCTGGGCTGA

Protein

MITNHISCSRHSGVKRSASPASESRPAVACGAGGAGRGAARSCRPAAPPALTALPALPASPALPACPLLVNVLLADTVLNVFRDHNFDSCTVCVCNEGTKVIGNIRGADAATYLSEGGEGSGEEPASCTCGFSAIVNRRLAHRSGLFYEDEMEITGCAETVSSAGGARLGDVTGAVLAQLGSVHAAPTALARAARSAAAAHHPHEHLRLNLLEYSDGGAAAAKALRAAGGAYAGAGPPCSNAPVGGSINESAPSAVHRWPFIGARAPRSSRDVVRLMRRLRPLLQDAIQKRCCGARMWDGVTGPLTWRQFHRLAGRRNEDLCEPQPVPSLLVGHDRDWISLSPYALRHWERLSLEPYAYSRDVAYVVVAADCDALADPLRAFFRELSTAYEACRLGRHRPVTRLARDGLVRTGAARSGETDEWAGPLPAGRLGRYLRAYSEALRTALVPQLAALNLDRTLLEGERSDSMRPPATPERPSSPTDHEAEPAPAPPPPAAPDDDEAGPPALVLYIVEPPAATAHRASALHALLRLAANTYNHLHHHNPLIKIISLESVSEQWSGAGVGAGARALAFTVYSGARRLLHHHANGKSLTGFGTAAAANLFLQAKDDKNRAPYRLYSPAWVLAAPRALREVAETWGQGGTADAVLFVSYCLSHDQRWLLAAATDSRGELLDTIAINIHVPHRSRRRRSGTARRLGLTKLMDFTLGVMSQAAQPWRLVIGRVGRIGHGELKGWSWLLSRKNLDQVSTTLKDLCGSCGSGAPCVLSACLVSTEPDSCLRLMADRFTPDERFSQASIQSHLHTPRDVSATHILVFPTSATTQSTPMTFEQPLANGEDGDMMLLDINDEDGEHIDELLNCDMFNNMWAPGSPRRADDDAASPTPHLAQQRLRDDGREERVGTVLQQPLALGYTVSTAPLAGMPAWWWASCAHLRDACPAFLKTALHLHSVHGADDYAAFTQRRDQPAHPLDSQTTTDVLRYVLEGYNALSWLALDTSTHDRLSCLPLHVQVLMQLYHAAAALG

Description

Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 13 family.

Uniprot

A0A2H1WHK1   A0A1C9EGH3   A0A212FFK1   A0A194RNL7   A0A0M8ZUW3   A0A154NY64   + More
E9J665   A0A224XHH6   A0A0A9WQW7   A0A0A9WZA5   A0A0L7QJV9   A0A139WD67   E0VG70   T1I7I8   A0A0T6AVH6   A0A2R7WIQ1   B0WMS7   A0A226ENH3   A0A1D2NFS0   A0A1J1IC58   A0A1J1IFV9   A0A087U1U8   A0A3S3SNK6   T1K941   R7UN35   V4A241   A0A1S3K2V1   A0A1S3K1S9  

Pubmed

22118469    26354079    21282665    25401762    26823975    18362917    + More
19820115    20566863    27289101    23254933   

EMBL

ODYU01008713    SOQ52543.1    KX778609    AON96593.1    AGBW02008811    OWR52508.1    + More
KQ459984    KPJ19102.1    KQ435833    KOX71620.1    KQ434782    KZC04609.1    GL768221    EFZ11754.1    GFTR01008937    JAW07489.1    GBHO01033460    GDHC01006463    JAG10144.1    JAQ12166.1    GBHO01033459    GDHC01006856    JAG10145.1    JAQ11773.1    KQ415041    KOC58908.1    KQ971362    KYB25781.1    AAZO01002026    AAZO01002027    AAZO01002028    DS235132    EEB12376.1    ACPB03005589    LJIG01022721    KRT79062.1    KK854734    PTY18275.1    DS232001    EDS31175.1    LNIX01000002    OXA59039.1    LJIJ01000056    ODN04072.1    CVRI01000047    CRK97338.1    CRK97337.1    KK117754    KFM71337.1    NCKU01000034    RWS17807.1    CAEY01001888    AMQN01007879    KB301608    ELU05357.1    KB201304    ESO97898.1   

Proteomes

UP000007151    UP000053240    UP000053105    UP000076502    UP000053825    UP000007266    + More
UP000009046    UP000015103    UP000002320    UP000198287    UP000094527    UP000183832    UP000054359    UP000285301    UP000015104    UP000014760    UP000030746    UP000085678   

Pfam

PF18296   MID_MedPIWI        + More
PF06333   Med13_C
PF11597   Med13_N
PF00515   TPR_1
PF13181   TPR_8

Interpro

IPR041285   MID_MedPIWI        + More
IPR009401   Med13_C       
IPR021643   Mediator_Med13_N_met/fun       
IPR013026   TPR-contain_dom       
IPR011990   TPR-like_helical_dom_sf       
IPR001440   TPR_1       
IPR019734   TPR_repeat       

SUPFAM

SSF48452   SSF48452       

Gene 3D

1.25.40.10    

ProteinModelPortal

A0A2H1WHK1   A0A1C9EGH3   A0A212FFK1   A0A194RNL7   A0A0M8ZUW3   A0A154NY64   + More
E9J665   A0A224XHH6   A0A0A9WQW7   A0A0A9WZA5   A0A0L7QJV9   A0A139WD67   E0VG70   T1I7I8   A0A0T6AVH6   A0A2R7WIQ1   B0WMS7   A0A226ENH3   A0A1D2NFS0   A0A1J1IC58   A0A1J1IFV9   A0A087U1U8   A0A3S3SNK6   T1K941   R7UN35   V4A241   A0A1S3K2V1   A0A1S3K1S9  

KEGG

101747187    K15164 mediator of RNA polymerase II transcription subunit 13 | (RefSeq) mediator of RNA polymerase

GO

GO:0016592   GO:0006357   GO:0003712   GO:0016021   GO:0005634   GO:0015074   GO:0050660   GO:0016627   GO:0006635   GO:0003995   GO:0008152   GO:0016491   GO:0003824  

Subcellular location

Nucleus  

Length:

1022

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.273330000000001

Exp number, first 60 AAs:

0.05165

Total prob of N-in:

0.00565

outside

1  -  1022

 

 

Pi

204.462673

Theta

207.047237

Tajima's D

0.006776

CLR

0.001006

CSRT

0.368981550922454

Interpretation

Uncertain