Silkworm Genome Informatics Database

Gene

KWMTBOMO05372 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002375

Annotation

PREDICTED:_cytoplasmic_dynein_1_intermediate_chain_isoform_X7_[Bombyx_mori]

Location

Bomo_Chr9(-):15710848-15737654 View in EpiBrowser

Full name

Cytoplasmic dynein 1 intermediate chain

Alternative Name

Dynein intermediate chain, cytosolic
Protein short wing

Location in the cell

Nuclear Reliability : 2.986

CDS

ATGTCGGATCGGAAGGCTGAGTTGGAGCGAAAGAAGGCGAAGCTCCGCGCCATAAGAGAGGATAAAGATCGGCGCCGCAGAGAAAAAGAACAGAAAGATGCTGAAGAAGCACTGCAACGGGCATCGGCCACATCTAGCCTGGACAGTCGTCGTGACATTGACGAGATGCTGTCCTCGCTTGGAGTGGCTCCAGTTAAGGATGTCCTCTCTTCTTTATCATCAATGACTTCACTGTCTCCACCTCAGACAGCCTCACCAGATGCCAGTTTACCGCATACAGATAAAGCCAGCCTACAATTGCAAGGCGGTCCAAAGAAGCAACCTCAAGAATTACAAGTCGTCTTCGTGCAGTCCACGGACATACCGCCCAAGGAGACGGTGATCTATACGAAGCAAACGCAGACCACCACGTCGGGCGTCACCGAACTGCGTGACGACGAGTACAATCTAAACCCGGGTTTAGAGTGGGAGGACGAGTTCACAGGAGACGACGAGGAGGCCGCCTTCCACGGTAAACTGCCCCCGGGGATACTGCCGCACGGCCTGCCCACCGTCAAGGAGGTCCAACCCGCAGTCACCGATGCGCCAGTCGAGAAGAAAGACGAAGAGAAAGAGAAGAAAGCGGTGCGCGAGCTGAGCGCTGACGAGAAGCAGACGATAATGCTGTCGGCCGAGTTCCAGAGGTTCATGAGTCGCGCCGGACGAGTCATCGAACGGGCGCTCGCCGAGTCCGTCGACATCTACACCGACTACACGGGCGGGGGTGACGGAGAGAACGCGCTTGACGACAAGTCAGCGGCCCGTCTTTCCCTGGTTCGTACCTTCGAGGAGGAACGCTGGTCGCGCGGACGGTGCGTGACCTGTCTGGACTGGTCCACGTTTCACCCTGAACTGGTGCTGGCCTCGTACTACAATAGTGACGACGCACCGCACGACCCTGACGGAGTGTGCCTGGTCTGGAACACCAAGTTCAAAAAGACCACTCCCGAAGACATATTCCACTGTCAGTCGGCGGTTATGAGCGCCACGTTTGCGAGGTTCCACCCTAACTTGATCCTCGGAGGCACGTATTCGGGACAGATCGTGCTGTGGGACAATCGCGTGCAAAAGCGAACCCCGGTGCAGCGCACGCCGCTGTCTTCGGTCGCGCACACTCACCCGGTGTACTGCCTGTCGGTGATAGGAAGCCAGAACGCGCACAACCTGATCTCGGTATCGACGGACGGGCGCCTCTGTTCCTGGTCCCTGGACATGCTGTCCCAGCCCCAGGAGACGCTGGAGCTGCAGCATCGCCAGGCCAAGCCGGTCGCCGTCACCTGCATGGACTGCCCCCAGACCATGCTCAACAACTTCGTGCTCGGATCCGAAGACGGAAACGTGTATACGGGATGCCTGTACGGGCAGCGCGCGGGCGTGACGGAGTGCGTGGAGGCGCACGCGGGCCCGCTGACGGGCGTGTCGTGCCACGCCGCCGCCGGGCCCGTGGACCTGGCGCACCTCTACCTCACCTGCTCCGTCGACTGGAGCGTCAAGCTCTGGTCGCTCAAGGAGAGCAAGCCGCTGTACTCGTTCGAGGACAACGGCGACTACCTGGTGGACGTGCGCTGGTCGCCCGCGCACCCCGCGCTCTTCGCCGCCGCCGACGCCGCCTCGCGCCTCGACCTCTGGAATCTCAACCGCGACACAGAGGTGCCGATAGCGAGCGTGCAGGCGGAAGGCGGGGCGGCCTTCAGCAGAGTGTCGTGGTCGCCAGCCGGCTCGCTCGTCACAGCCGGAGACGACAGGGGCAAGATATCCGTCTACGAACTTGCAGAGCAAGTTTGGTCACCCCGGCACGACGAATGGAACAAGTTGGTCTACACGCTTCAAGAACTTCGGAACAACCAAGCTGACGATGATGCGGCACTCTCACCACCGCCGTCGTTGTCGTCAATCGCTTCTATCGCTTCAAACCCACTACGATAA

Protein

MSDRKAELERKKAKLRAIREDKDRRRREKEQKDAEEALQRASATSSLDSRRDIDEMLSSLGVAPVKDVLSSLSSMTSLSPPQTASPDASLPHTDKASLQLQGGPKKQPQELQVVFVQSTDIPPKETVIYTKQTQTTTSGVTELRDDEYNLNPGLEWEDEFTGDDEEAAFHGKLPPGILPHGLPTVKEVQPAVTDAPVEKKDEEKEKKAVRELSADEKQTIMLSAEFQRFMSRAGRVIERALAESVDIYTDYTGGGDGENALDDKSAARLSLVRTFEEERWSRGRCVTCLDWSTFHPELVLASYYNSDDAPHDPDGVCLVWNTKFKKTTPEDIFHCQSAVMSATFARFHPNLILGGTYSGQIVLWDNRVQKRTPVQRTPLSSVAHTHPVYCLSVIGSQNAHNLISVSTDGRLCSWSLDMLSQPQETLELQHRQAKPVAVTCMDCPQTMLNNFVLGSEDGNVYTGCLYGQRAGVTECVEAHAGPLTGVSCHAAAGPVDLAHLYLTCSVDWSVKLWSLKESKPLYSFEDNGDYLVDVRWSPAHPALFAAADAASRLDLWNLNRDTEVPIASVQAEGGAAFSRVSWSPAGSLVTAGDDRGKISVYELAEQVWSPRHDEWNKLVYTLQELRNNQADDDAALSPPPSLSSIASIASNPLR

Description

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).

Subunit

Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).

Similarity

Belongs to the dynein intermediate chain family.

Keywords

3D-structure Alternative splicing Complete proteome Cytoplasm Cytoskeleton Dynein Lysosome Membrane Microtubule Motor protein Nucleus Reference proteome Repeat Transport WD repeat

Feature

chain Cytoplasmic dynein 1 intermediate chain
splice variant In isoform 1a.

Uniprot

H9IYP1 A0A1E1W739 A0A1E1WB06 A0A0N1I6A2 A0A212EUT1 A0A194QPM5 + More
A0A2J7R9J8 A0A2J7R9L0 A0A2J7R9L7 A0A2J7R9J9 E9ILU2 A0A026VSN3 A0A1Y1KFS0 A0A1Y1KLQ1 A0A195CGM0 E2B7N3 A0A2J7R9K9 A0A158N9C5 A0A1B6E0H3 K7J2Y5 A0A2J7R9L8 A0A067RHB9 A0A0K8T000 A0A151I3R6 A0A2A3E2X5 D6X3Z7 F5HJL8 A0A088A3S9 A0A195F961 A0A0A9X238 A0A182P8K1 A0A0Q9XFY1 A0A1L8E5Q3 A0A182YK41 A0A182W555 A0A182N0U5 A0A0R3P5B2 A0A0K8T0J0 B0W0K8 A0A1W4UQF0 A0A0R1EI12 A0A0L0BSR3 A0A0Q5T6V6 Q24246-8 A0A1Y1KFS3 A0A182RM32 A0A182LS29 Q7QF61 A0A1Q3FEQ4 A0A0Q9XSD4 A0A182V7Y8 A0A0Q9XFZ6 A0A151J599 A0A1W4UQE5 A0A182QNV6 A0A2M4A4S0 A0A0R3P0F7 A0A0K8T429 A0A0R1EHZ7 A0A0Q5T466 A0A1W4UQP4 A0A1S4J2I2 A0A151XFY1 A0A1W4UDR5 A0A0R1EC39 A0A0Q5T460 A0A0R3P0R5 Q24246-9 Q24246-5 A4V4T4 A0A0P4WQJ3 A0A0K8TWS9 A0A1W4UQN3 X2JLF7 E8NH86 A0A0K8SZM4 E1ZZ33 B4L7X2 A0A034VXA0 A0A0K8SZJ1 A0A0R1EBZ5 A0A1J1IX29 A0A0Q5T4E9 A0A1W4UQN8 A0A1W4US68 Q29GW3 A0A0R1EE75 A0A0R1EC90 A0A0Q5T454 A0A2M3YYY3 A0A0Q9XP27 A0A0K8WFT2 A0A0Q9WU11 Q24246-7 B4PY10 B3NWG7 A0A2M4BH09 Q24246-6 A0A1W4UDR1 W8BY87

Pubmed

19121390 26354079 22118469 21282665 24508170 28004739 + More
20798317 21347285 20075255 24845553 18362917 19820115 12364791 14747013 17210077 25401762 17994087 25244985 15632085 17550304 26108605 9774695 11071907 10731132 12537572 12537568 12537573 12537574 16110336 17569856 17569867 26109357 26109356 25348373 24495485

EMBL

BABH01011178 BABH01011179 BABH01011180 BABH01011181 GDQN01008238 JAT82816.1 + More
GDQN01006891 JAT84163.1 KQ460864 KPJ11810.1 AGBW02012297 OWR45246.1 KQ458714 KPJ05431.1 NEVH01006582 PNF37518.1 PNF37521.1 PNF37523.1 PNF37517.1 GL764129 EFZ18331.1 KK108821 EZA46625.1 GEZM01084985 JAV60342.1 GEZM01084989 JAV60336.1 KQ977791 KYM99874.1 GL446193 EFN88311.1 PNF37519.1 ADTU01009379 ADTU01009380 ADTU01009381 GEDC01005924 GEDC01005921 GEDC01001963 JAS31374.1 JAS31377.1 JAS35335.1 PNF37522.1 KK852470 KDR23246.1 GBRD01007105 JAG58716.1 KQ976484 KYM83683.1 KZ288413 PBC26067.1 KQ971379 EEZ97487.2 AAAB01008846 EGK96479.1 KQ981727 KYN36747.1 GBHO01029555 GBRD01006717 JAG14049.1 JAG59104.1 CH933814 KRG07440.1 GFDF01000110 JAV13974.1 CH379064 KRT06749.1 GBRD01007106 JAG58715.1 DS231818 EDS41310.1 CM000162 KRK07073.1 JRES01001419 KNC23082.1 CH954180 KQS30128.1 AF070687 AF070689 AF070690 AF070691 AF070692 AF070693 AF070694 AF070695 AF070696 AF070697 AF070698 AF070699 AF263371 AE014298 BT016101 L41945 GEZM01084987 JAV60339.1 AXCM01000244 EAA06242.4 GFDL01009014 JAV26031.1 KRG07441.1 KRG07436.1 KQ980026 KYN18200.1 AXCN02002174 GGFK01002438 MBW35759.1 KRT06750.1 GBRD01005675 JAG60146.1 KRK07057.1 KQS30124.1 KQ982174 KYQ59294.1 KRK07062.1 KQS30121.1 KRT06748.1 BT126328 AAS65417.1 AAS65418.1 AEB72008.1 GDRN01070702 JAI63821.1 GDHF01033397 JAI18917.1 AHN59957.1 BT125962 ADX35941.1 GBRD01007109 JAG58712.1 GL435281 EFN73552.1 EDW05547.2 GAKP01012794 JAC46158.1 GBRD01007113 JAG58708.1 KRK07056.1 CVRI01000063 CRL04258.1 KQS30125.1 EAL31996.3 KRK07070.1 KRK07067.1 KQS30131.1 GGFM01000722 MBW21473.1 KRG07434.1 GDHF01002288 JAI50026.1 CH964239 KRF99564.1 EDX02982.2 EDV46787.2 GGFJ01002947 MBW52088.1 GAMC01012336 JAB94219.1

Proteomes

UP000005204 UP000053240 UP000007151 UP000053268 UP000235965 UP000053097 + More
UP000078542 UP000008237 UP000005205 UP000002358 UP000027135 UP000078540 UP000242457 UP000007266 UP000007062 UP000005203 UP000078541 UP000075885 UP000009192 UP000076408 UP000075920 UP000075884 UP000001819 UP000002320 UP000192221 UP000002282 UP000037069 UP000008711 UP000000803 UP000075900 UP000075883 UP000075903 UP000078492 UP000075886 UP000075809 UP000000311 UP000183832 UP000007798

PRIDE

H9IYP1 Q24246 A4V4T4 X2JLF7 E8NH86

Pfam

PF11540 Dynein_IC2 + More
PF00400 WD40

Interpro

IPR001680   WD40_repeat        + More
IPR015943   WD40/YVTN_repeat-like_dom_sf
IPR036322   WD40_repeat_dom_sf
IPR025956   DYNC1I1/DYNC1I2
IPR017986   WD40_repeat_dom

SUPFAM

SSF50978 SSF50978

Gene 3D

2.130.10.10

ProteinModelPortal

H9IYP1 A0A1E1W739 A0A1E1WB06 A0A0N1I6A2 A0A212EUT1 A0A194QPM5 + More
A0A2J7R9J8 A0A2J7R9L0 A0A2J7R9L7 A0A2J7R9J9 E9ILU2 A0A026VSN3 A0A1Y1KFS0 A0A1Y1KLQ1 A0A195CGM0 E2B7N3 A0A2J7R9K9 A0A158N9C5 A0A1B6E0H3 K7J2Y5 A0A2J7R9L8 A0A067RHB9 A0A0K8T000 A0A151I3R6 A0A2A3E2X5 D6X3Z7 F5HJL8 A0A088A3S9 A0A195F961 A0A0A9X238 A0A182P8K1 A0A0Q9XFY1 A0A1L8E5Q3 A0A182YK41 A0A182W555 A0A182N0U5 A0A0R3P5B2 A0A0K8T0J0 B0W0K8 A0A1W4UQF0 A0A0R1EI12 A0A0L0BSR3 A0A0Q5T6V6 Q24246-8 A0A1Y1KFS3 A0A182RM32 A0A182LS29 Q7QF61 A0A1Q3FEQ4 A0A0Q9XSD4 A0A182V7Y8 A0A0Q9XFZ6 A0A151J599 A0A1W4UQE5 A0A182QNV6 A0A2M4A4S0 A0A0R3P0F7 A0A0K8T429 A0A0R1EHZ7 A0A0Q5T466 A0A1W4UQP4 A0A1S4J2I2 A0A151XFY1 A0A1W4UDR5 A0A0R1EC39 A0A0Q5T460 A0A0R3P0R5 Q24246-9 Q24246-5 A4V4T4 A0A0P4WQJ3 A0A0K8TWS9 A0A1W4UQN3 X2JLF7 E8NH86 A0A0K8SZM4 E1ZZ33 B4L7X2 A0A034VXA0 A0A0K8SZJ1 A0A0R1EBZ5 A0A1J1IX29 A0A0Q5T4E9 A0A1W4UQN8 A0A1W4US68 Q29GW3 A0A0R1EE75 A0A0R1EC90 A0A0Q5T454 A0A2M3YYY3 A0A0Q9XP27 A0A0K8WFT2 A0A0Q9WU11 Q24246-7 B4PY10 B3NWG7 A0A2M4BH09 Q24246-6 A0A1W4UDR1 W8BY87

PDB

6F3A E-value=8.98383e-148, Score=1345

KEGG

101741734 K10415 dynein intermediate chain, cytosolic | (RefSeq) cytoplasmic dynein 1 intermediate chain

PATHWAY

04145 Phagosome - Bombyx mori (domestic silkworm)

GO

GO:0005868 GO:0007018 GO:0045503 GO:0045504 GO:0016021 GO:0007349 GO:0000226 GO:0005874 GO:0043005 GO:0001754 GO:0008088 GO:0051642 GO:0005765 GO:0007051 GO:0007291 GO:0034452 GO:0034501 GO:0031965 GO:0003774 GO:0032991 GO:0008574 GO:0005515 GO:0016020 GO:0003779 GO:0008270 GO:0006511 GO:0005525 GO:0016491 GO:0003824

Subcellular location

Lysosome membrane
Nucleus membrane

Length:

654

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00987999999999998

Exp number, first 60 AAs:

9e-05

Total prob of N-in:

0.00106

outside

1 - 654

Pi

283.247804

Theta

178.141627

Tajima's D

1.08225

CLR

0.372548

CSRT

0.672266386680666

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics