Gene

KWMTBOMO05361

Pre Gene Modal

BGIBMGA002541

Annotation

PREDICTED:_phospholipase_B1?_membrane-associated-like_[Bombyx_mori]

Location

Bomo_Chr9(+):15507386-15537100      View in EpiBrowser

Full name

Serine/threonine-protein phosphatase      

Location in the cell

PlasmaMembrane   Reliability : 1.55

CDS

ATGCGGCTGGCACTCGGTCAACTTTTGCTGTTGACTGATATTGTTGCTACTAATTTGAATTTAACGTTTCTCGAGGATGTGTGGAGGGTCCGCTATCCAGTCAGAAGGTCGCACGTTCGACGCCAACGCGCTATCCCACCGTCGACACCATTTCCATGCGAAGATGCCTTGTCCTGGGGCAGAAGTAAAGAACGGCCTACATCAGTGCACAAACTCCGACCTGGTGATATTGATGTGGTGGCTGCTATCGGAGACTCGTTGGTGGCTGGCAGTGGCGCCCTGGAGGAGTTCGCTCTGGGCGCCTTTGTAGAGTACCGCGGCGTCTCTTGGTGCATGGGTGGTGACGCAACATGGCGTGAGTTCCTGACGCTACCCAACATCCTGAAAGAGTTCAACCCGAACCTGAAAGGTTACTCCACGGGAACTGGAGAATGGATCACAAAAAACTCTAAACTCAACGTGGCCTTCCCTGTGGCTTCTGATGAAGACGCTTTGAAGCAGGCTAAGATCATAGTGGCCAGGATGCGTGCGTCCCCCGACATCGACATAGCTCAAGACTGGAAGATGATCACGATGTTCATTGGTGCTAACGATATCTGCTCGGCCGCCTGCATCAACCCGGTATCCTGGTCGCCGGCTGCTCACGCGAGAAAGCTGGCCAACGCCTTGGACTATCTTCAGGAAAAGCTGCCGAGGACTATCGTTAATTTAGTTCCTGTATTAGATGTATCGGTATCCGTTCGGGTGCTCCGCCCCATGATGTGTCGCCTGATGCACTCGCTGTTCTGCTCGTGCTTCCACCGCGGCGGAGACGAGCTCCAGGACATCGTGAGGATGTCGCGGCTCTATCAGAAACACGAGGCGTTGCTTGTGGACAGCGGTCGTTACGACGCTCGCGAAGACTTCACGGTGGTGGTGCAGCCCTTCATGAGGCTGTTCAACGCGCCCTTCCCCCCCAAGCAGCCGCTGCCCCTCGTCATACACCAGTCCTACATCACGCACGACTGCTTCCACTTCTCGCAGAAAGGACACGCTTTAGCGGCGAATCTCCTGTGGAACAACCTTCTGGAGCCGGTCGGCAACAAATCTGACAATGTGCCGCCGGTTTTAATGCGTTCCTTCCGCTGCCCTTCGCGGCAGGCGCCTTTCATATTCACTGCTCGCAACACGAGGACCTACCTATTGACGGGGCAGCAGGAAGGCGCTTTTGAGTTATGA

Protein

MRLALGQLLLLTDIVATNLNLTFLEDVWRVRYPVRRSHVRRQRAIPPSTPFPCEDALSWGRSKERPTSVHKLRPGDIDVVAAIGDSLVAGSGALEEFALGAFVEYRGVSWCMGGDATWREFLTLPNILKEFNPNLKGYSTGTGEWITKNSKLNVAFPVASDEDALKQAKIIVARMRASPDIDIAQDWKMITMFIGANDICSAACINPVSWSPAAHARKLANALDYLQEKLPRTIVNLVPVLDVSVSVRVLRPMMCRLMHSLFCSCFHRGGDELQDIVRMSRLYQKHEALLVDSGRYDAREDFTVVVQPFMRLFNAPFPPKQPLPLVIHQSYITHDCFHFSQKGHALAANLLWNNLLEPVGNKSDNVPPVLMRSFRCPSRQAPFIFTARNTRTYLLTGQQEGAFEL

Catalytic Activity

H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate

Similarity

Belongs to the tubulin family.
Belongs to the PPP phosphatase family.

Uniprot

H9IZ56   A0A2A4IVJ9   A0A2H1V6A5   A0A194QKJ7   A0A212EUX1   A0A3S2PAB3   + More
A0A0N0PE65   J3JYA3   N6TG14   A0A139WMW2   A0A0T6BGK4   A0A2S2PTK3   E0W2Q1   J9JUN4   A0A2H8TS51   A0A1B6D4F4   A0A2S2QE85   A0A1B6JF64   U4U746   K7J549   A0A232FJT4   T1H8D1   A0A0L7RJJ4   A0A3L8DTY4   A0A146MB10   A0A0A9W7F4   A0A087ZUF6   A0A151XF11   A0A154PPZ3   A0A2K8JS64   A0A151JC71   A0A195FKK9   A0A026WZG1   A0A0M9A7Y5   F4WB31   A0A2A3EJX1   E2C7F9   B7S8S6   A0A310S7A5   A0A195BFH9   E2AGF9   B7S8I6   A0A2R7WB09   A0A158NRF5   A0A067R8Q6   A0A151IG51   A0A1B6GTS3   A0A267H6N9   A0A2J7RI88   A0A267H3R8   A0A267EF37   E0W2N7   A0A267FY75   A0A2J7RI75   A0A267E0I1   A0A1I8GLI6   A0A210Q1F6   A0A210Q1G9   A0A1I8JJE3   V4AFX0   A0A1W4W312   A0A1W4WDL2   A0A3M7SJF1   A0A336M5D8   A0A1I8HC98   A0A3M7RLL2   H0YWG9   H0YWH2   A0A087VH47   A0A0B7ACV2   F1NFV7   A0A2C9LEZ7   G1NDE1   A0A2C9LF84   A0A1I8HI08   A0A182MTA8   A0A0F8C489   A0A091I1M3   A0A3S2TX14   A0A1I8JHV6   A0A3P9L5U9   A0A154PPJ5   K7GCY6   H2MDS7   A0A3P9L606   A0A182Q9B2   A0A1W4WEJ9   A0A099YQF9   W8BV54   A0A091RNT0   A0A084VXB3   A0A182MY43   A0A182MY44   A0A2R2MU56   A0A0K8WE83   A0A3L8SRH5   K7J548  

EC Number

3.1.3.16

Pubmed

19121390    26354079    22118469    22516182    23537049    18362917    + More
19820115    20566863    20075255    28648823    30249741    26823975    25401762    24508170    21719571    20798317    21347285    24845553    26392545    28812685    23254933    30375419    20360741    15592404    15562597    20838655    25835551    17554307    17381049    24495485    24438588    30282656   

EMBL

BABH01011159    NWSH01007004    PCG63153.1    ODYU01000898    SOQ36347.1    KQ458714    + More
KPJ05440.1    AGBW02012297    OWR45254.1    RSAL01000148    RVE45832.1    KQ459934    KPJ19265.1    BT128227    AEE63188.1    APGK01029202    KB740727    ENN79334.1    KQ971312    KYB29358.1    LJIG01000454    KRT86486.1    GGMR01020193    MBY32812.1    DS235879    EEB19907.1    ABLF02030215    GFXV01004994    MBW16799.1    GEDC01016724    JAS20574.1    GGMS01006845    MBY76048.1    GECU01009914    JAS97792.1    KB631815    ERL86421.1    AAZX01005789    AAZX01005912    NNAY01000117    OXU30800.1    ACPB03021114    KQ414580    KOC71045.1    QOIP01000004    RLU23831.1    GDHC01002000    JAQ16629.1    GBHO01041181    GBRD01004149    JAG02423.1    JAG61672.1    KQ982205    KYQ58976.1    KQ435012    KZC13787.1    KY031129    ATU82880.1    KQ979122    KYN22555.1    KQ981522    KYN40534.1    KK107054    EZA61432.1    KQ435724    KOX78316.1    GL888056    EGI68586.1    KZ288223    PBC31990.1    GL453369    EFN76146.1    EF710652    ACE75301.1    KQ780345    OAD51959.1    KQ976504    KYM82942.1    GL439310    EFN67492.1    EF710647    ACE75211.1    KK854504    PTY16411.1    ADTU01023893    ADTU01023894    ADTU01023895    ADTU01023896    KK852809    KDR15978.1    KQ977731    KYN00249.1    GECZ01003929    JAS65840.1    NIVC01000032    PAA93222.1    NEVH01003505    PNF40543.1    NIVC01000056    PAA92354.1    NIVC01002198    PAA60056.1    EEB19893.1    NIVC01000667    PAA78765.1    PNF40534.1    NIVC01002814    PAA55063.1    NEDP02005257    OWF42571.1    OWF42572.1    KB200129    ESP02914.1    REGN01001272    RNA35913.1    UFQS01000582    UFQT01000582    SSX05123.1    SSX25484.1    REGN01003131    RNA24384.1    ABQF01049157    ABQF01049158    ABQF01049159    KL493167    KFO11939.1    HACG01031984    CEK78849.1    AADN05000005    AXCM01006145    KQ042798    KKF10562.1    KL532784    KFO93358.1    CM012458    RVE57408.1    KZC13789.1    AGCU01036872    AGCU01036873    AGCU01036874    AGCU01036875    AGCU01036876    AGCU01036877    AGCU01036878    AGCU01036879    AXCN02002030    KL885127    KGL72524.1    GAMC01005707    JAC00849.1    KK823152    KFQ41033.1    ATLV01017908    KE525196    KFB42607.1    GDHF01002917    JAI49397.1    QUSF01000008    RLW07140.1    AAZX01017768   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000283053    UP000053240    + More
UP000019118    UP000007266    UP000009046    UP000007819    UP000030742    UP000002358    UP000215335    UP000015103    UP000053825    UP000279307    UP000005203    UP000075809    UP000076502    UP000078492    UP000078541    UP000053097    UP000053105    UP000007755    UP000242457    UP000008237    UP000078540    UP000000311    UP000005205    UP000027135    UP000078542    UP000215902    UP000235965    UP000095280    UP000242188    UP000030746    UP000192223    UP000276133    UP000007754    UP000000539    UP000076420    UP000001645    UP000075883    UP000265180    UP000007267    UP000001038    UP000075886    UP000053641    UP000030765    UP000075884    UP000085678    UP000276834   

PRIDE

H9IZ56   

Pfam

PF00657   Lipase_GDSL        + More
PF00091   Tubulin
PF00149   Metallophos
PF16891   STPPase_N

Interpro

IPR001087   GDSL        + More
IPR035547   Phospholipase_B       
IPR038885   PLB1       
IPR036514   SGNH_hydro_sf       
IPR003008   Tubulin_FtsZ_GTPase       
IPR002452   Alpha_tubulin       
IPR036525   Tubulin/FtsZ_GTPase_sf       
IPR000217   Tubulin       
IPR008265   Lipase_GDSL_AS       
IPR006186   Ser/Thr-sp_prot-phosphatase       
IPR031675   STPPase_N       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR029052   Metallo-depent_PP-like       

SUPFAM

SSF52490   SSF52490       

Gene 3D

3.40.50.1110     3.40.50.1440     3.60.21.10    

CDD

cd01824  Phospholipase_B_like

ProteinModelPortal

H9IZ56   A0A2A4IVJ9   A0A2H1V6A5   A0A194QKJ7   A0A212EUX1   A0A3S2PAB3   + More
A0A0N0PE65   J3JYA3   N6TG14   A0A139WMW2   A0A0T6BGK4   A0A2S2PTK3   E0W2Q1   J9JUN4   A0A2H8TS51   A0A1B6D4F4   A0A2S2QE85   A0A1B6JF64   U4U746   K7J549   A0A232FJT4   T1H8D1   A0A0L7RJJ4   A0A3L8DTY4   A0A146MB10   A0A0A9W7F4   A0A087ZUF6   A0A151XF11   A0A154PPZ3   A0A2K8JS64   A0A151JC71   A0A195FKK9   A0A026WZG1   A0A0M9A7Y5   F4WB31   A0A2A3EJX1   E2C7F9   B7S8S6   A0A310S7A5   A0A195BFH9   E2AGF9   B7S8I6   A0A2R7WB09   A0A158NRF5   A0A067R8Q6   A0A151IG51   A0A1B6GTS3   A0A267H6N9   A0A2J7RI88   A0A267H3R8   A0A267EF37   E0W2N7   A0A267FY75   A0A2J7RI75   A0A267E0I1   A0A1I8GLI6   A0A210Q1F6   A0A210Q1G9   A0A1I8JJE3   V4AFX0   A0A1W4W312   A0A1W4WDL2   A0A3M7SJF1   A0A336M5D8   A0A1I8HC98   A0A3M7RLL2   H0YWG9   H0YWH2   A0A087VH47   A0A0B7ACV2   F1NFV7   A0A2C9LEZ7   G1NDE1   A0A2C9LF84   A0A1I8HI08   A0A182MTA8   A0A0F8C489   A0A091I1M3   A0A3S2TX14   A0A1I8JHV6   A0A3P9L5U9   A0A154PPJ5   K7GCY6   H2MDS7   A0A3P9L606   A0A182Q9B2   A0A1W4WEJ9   A0A099YQF9   W8BV54   A0A091RNT0   A0A084VXB3   A0A182MY43   A0A182MY44   A0A2R2MU56   A0A0K8WE83   A0A3L8SRH5   K7J548  

KEGG

101738273    K14621 phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5] | (RefSeq) phospholipase B1, membr

PATHWAY

00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)
00565    Ether lipid metabolism - Bombyx mori (domestic silkworm)
00590    Arachidonic acid metabolism - Bombyx mori (domestic silkworm)
00591    Linoleic acid metabolism - Bombyx mori (domestic silkworm)
00592    alpha-Linolenic acid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004620   GO:0005200   GO:0003924   GO:0005737   GO:0005525   GO:0007017   GO:0005874   GO:0006644   GO:0016021   GO:0006629   GO:0004622   GO:0031526   GO:0004623   GO:0050253   GO:2000344   GO:0046872   GO:0004721   GO:0016788   GO:0004729   GO:0006779   GO:0000220   GO:0016020   GO:0008270   GO:0006511   GO:0016491   GO:0003824  

PANTHER

PTHR21325  

Subcellular location

  

SignalP

Position:   1 - 17,         Likelihood:  0.547286

 

 

Length:

405

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06549

Exp number, first 60 AAs:

0.04502

Total prob of N-in:

0.00271

outside

1  -  405

 

 

Pi

171.348936

Theta

154.020503

Tajima's D

0.355905

CLR

0.443944

CSRT

0.475426228688566

Interpretation

Uncertain