Gene

KWMTBOMO05359

Pre Gene Modal

BGIBMGA002540

Annotation

Protoporphyrinogen_oxidase_[Operophtera_brumata]

Location

Bomo_Chr9(+):15487256-15489393      View in EpiBrowser

Full name

Protoporphyrinogen oxidase      

Location in the cell

Cytoplasmic   Reliability : 1.643 Mitochondrial   Reliability : 1.514

CDS

ATGGCCGCTATACTTGGCGAGGCTACTAATTACTGCGGCGGATGGATTAAATCCATAAGGACAAAGGATTACGTTTTTGAGCAAGGCCCAAGAACTATACGGCCCAAAGGAGTTACCGGGCTTAATACACTGAATATGATACAAGATTTGGGCCTTAGCGAGCATATATCACCTATAAAACCGGACCACCCTGCCGCTAGGAACAGAATGATATACGTAAACAATAATTTGTATTTATTGCCTTCAAGTTTAAAAGGTGTATTCCAAAAGAATGAGCCCTTTTCGAAGCCGCTGATTTACGCACTTTATCACGATTTAAAGAAGCCTCACAAACAGTTGAAAGATGATTCGATTTATAACTTCGTTGAAAGGAGATTCGGGAAGGAAATTGCTGATTATGCAATTTCACCAATGATTTGTGGCATCTGTGCTGGGGACGCTAAAGAGATTTCAGTTAAATTTTTAATGAAAACTCTATTTGAATGGGAGCAAACCCACGGAGGCGTCGTAAAAGGTTTGATGAAGTCATTGTTCAGTTCGAAGACTGGAAATGAATTAGTACTAAGTGATTTAGCAAGGAAGGCTCAGGAAGAAAAATGGAGTGTTTACACGATAAAAGGTGGCTTGGAAATGTTTCCCAACAAACTGCAAGCCCACTTAAAAGATAACAATGTAACCATGAACTTGAGTACAAAAGTTGAAGCCATAGAATTTGTGGACTCTGGATCTGTTTCGTTAAATATTCAAACAGGAGAAAAGTTATCAGTGAATCATGTGTATTCTTCAATACCAGCTTATTGTCTAGCAAGCTTAGTACAAAAACAGCATCCAGAATTAGCTAAAACACTAAAAGATATACCATTTGTAACTGTGGGAATAGTAAATTTGTATTTTGCCACTCAAAAACCTTTGATAAAGCCGGCATTTGGTTTCTTAGTTCCTCCGATTGAAAATTCTCCCATATTAGGTGTAGTCTTTGATTCGTGTTGTATGCCAGATCAAAATGGAACTGTTTTAACAGTGATGCTTGGAGGCAGATGGTTTGAAGAAAAATTTGGAAAAAATACAACATCGGAGAATTTATATAACATTGCTGTCAAAGAAGTAGGTTCGATATTGGATATTAAAGACAAACCAACAGCATTTAATGTGAATATTTTAAATAGATGCATACCTCAGTATGTAGTAGGACATTATGAGAGAGTTGATGAGATTAGACAATACATAAAAAGTAATAATTTGCCAATTTCTTTAATAGGCAGCAGTTATGATGGTGCCAACTAA

Protein

MAAILGEATNYCGGWIKSIRTKDYVFEQGPRTIRPKGVTGLNTLNMIQDLGLSEHISPIKPDHPAARNRMIYVNNNLYLLPSSLKGVFQKNEPFSKPLIYALYHDLKKPHKQLKDDSIYNFVERRFGKEIADYAISPMICGICAGDAKEISVKFLMKTLFEWEQTHGGVVKGLMKSLFSSKTGNELVLSDLARKAQEEKWSVYTIKGGLEMFPNKLQAHLKDNNVTMNLSTKVEAIEFVDSGSVSLNIQTGEKLSVNHVYSSIPAYCLASLVQKQHPELAKTLKDIPFVTVGIVNLYFATQKPLIKPAFGFLVPPIENSPILGVVFDSCCMPDQNGTVLTVMLGGRWFEEKFGKNTTSENLYNIAVKEVGSILDIKDKPTAFNVNILNRCIPQYVVGHYERVDEIRQYIKSNNLPISLIGSSYDGAN

Description

Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.

Catalytic Activity

3 O2 + protoporphyrinogen IX = 3 H2O2 + protoporphyrin IX

Cofactor

FAD

Subunit

Monomer. Homodimer.

Similarity

Belongs to the protoporphyrinogen oxidase family.

Uniprot

A0A0L7L830   A0A212EUU5   A0A3S2LWV7   A0A194QIV2   A0A0N0PEK3   A0A2A4ITR2   + More
A0A2H1WFD0   A0A1E1WFJ7   B0WEW7   A0A2P8XBA8   Q0IFY9   A0A1Q3F4X0   A0A182USH9   A0A1S4F5S5   A0A182GQK5   A0A182K861   A0A182KXY4   A0A182QLW1   A0A182I933   A0A182WVF4   A0A182F8E6   A0A182TPW0   A0A182NCK9   Q7PQE8   A0A1B0GNK9   A0A182PU01   A0A182JGV6   D6W9X5   A0A1I8QCQ9   A0A182W2Z5   A0A067QVF3   A0A182M9Q0   A0A0L0C968   A0A2J7RIM2   A0A182YEV2   A0A336KLR4   A0A084WR34   A0A182R8D3   W5JL42   T1PBF1   A0A1I8N0G2   W8BF45   A0A1A9XMX3   A0A1B0BYN3   A0A1A9WC25   A0A1A9UQ46   A0A1B6ID66   A0A1B0G1C1   A0A1B6L6C7   A0A1B6GAE0   D3TPT8   A0A1B0A8U7   B4JEJ4   A0A034WCU1   A0A0A1WVJ5   A0A0K8V4B8   A0A1S3D9S5   B4GPF6   N6U8I4   A0A0J7L3P6   B4LW33   A0A0M4ENR0   Q29BZ1   A0A1J1HVC6   A0A3B0JG34   Q9U8D0   B3M044   J3JYB3   A0A1W4W2S9   Q9VC52   A0A1Y1N1Y6   A0A069DTX3   A0A2R7X504   A0A023EZE1   A0A0P4VSK0   T1HLY0   A0A026WES5   A0A0M4EPB7   A0A1B6CEV5   B4K513   A0A3L8E463   A0A0A9YYJ2   A0A0V0GBX7   B4N8T6   A0A1W4W220   A0A0C9R5A1   A0A232F9I7   K7IR22   B3P704   I3RSG1   A0A154PPL3   B4PVR1   E2AU30   B4HH53   A0A151WP02   E9GIC4   B4QTQ6  

EC Number

1.3.3.4

Pubmed

26227816    22118469    26354079    29403074    17510324    26483478    + More
20966253    12364791    14747013    17210077    18362917    19820115    24845553    26108605    25244985    24438588    20920257    23761445    25315136    24495485    20353571    17994087    25348373    25830018    23537049    15632085    22516182    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28004739    26334808    25474469    27129103    24508170    30249741    25401762    26823975    28648823    20075255    22328714    17550304    20798317    21292972   

EMBL

JTDY01002394    KOB71504.1    AGBW02012297    OWR45256.1    RSAL01000148    RVE45834.1    + More
KQ458714    KPJ05442.1    KQ459934    KPJ19263.1    NWSH01007004    PCG63155.1    ODYU01008280    SOQ51727.1    GDQN01005281    JAT85773.1    DS231912    EDS25825.1    PYGN01004758    PYGN01000725    PSN29274.1    PSN41636.1    CH477281    EAT44935.1    GFDL01012441    JAV22604.1    JXUM01015647    KQ560436    KXJ82424.1    AXCN02001184    APCN01003167    AAAB01008888    EAA08942.3    AJVK01029521    KQ971312    EEZ98095.1    KK852898    KDR14166.1    AXCM01000016    JRES01000835    KNC27944.1    NEVH01003495    PNF40677.1    UFQS01000615    UFQT01000615    SSX05429.1    SSX25789.1    ATLV01025911    KE525402    KFB52678.1    ADMH02001252    ETN63479.1    KA645460    AFP60089.1    GAMC01009253    JAB97302.1    JXJN01022712    JXJN01023025    GECU01022840    JAS84866.1    CCAG010023381    GEBQ01020699    JAT19278.1    GECZ01010370    JAS59399.1    EZ423440    ADD19716.1    CH916369    EDV93125.1    GAKP01007354    JAC51598.1    GBXI01011450    JAD02842.1    GDHF01018567    JAI33747.1    CH479186    EDW39039.1    APGK01044427    KB741026    ENN74912.1    LBMM01000784    KMQ97507.1    CH940650    EDW66538.1    CP012526    ALC46376.1    CM000070    EAL26855.1    CVRI01000021    CRK91506.1    OUUW01000005    SPP81297.1    AF098937    AAF00577.1    CH902617    EDV42001.1    BT128238    AEE63198.1    AE014297    AY058695    AAF56323.1    AAL13924.1    GEZM01015027    JAV91921.1    GBGD01001341    JAC87548.1    KK856863    PTY26500.1    GBBI01004100    JAC14612.1    GDKW01001153    JAI55442.1    ACPB03006649    KK107260    EZA54151.1    ALC45922.1    GEDC01025448    GEDC01014916    JAS11850.1    JAS22382.1    CH933806    EDW13984.1    QOIP01000001    RLU27205.1    GBHO01009000    GBHO01008999    GBRD01002760    GDHC01017431    GDHC01014199    JAG34604.1    JAG34605.1    JAG63061.1    JAQ01198.1    JAQ04430.1    GECL01000524    JAP05600.1    CH964232    EDW81537.1    GBYB01007957    JAG77724.1    NNAY01000669    OXU27093.1    CH954182    EDV53824.1    JQ611724    AFK29246.1    KQ435012    KZC13835.1    CM000160    EDW98910.1    GL442767    EFN63073.1    CH480815    EDW43529.1    KQ982893    KYQ49594.1    GL732546    EFX80796.1    CM000364    EDX14260.1   

Proteomes

UP000037510    UP000007151    UP000283053    UP000053268    UP000053240    UP000218220    + More
UP000002320    UP000245037    UP000008820    UP000075903    UP000069940    UP000249989    UP000075881    UP000075882    UP000075886    UP000075840    UP000076407    UP000069272    UP000075902    UP000075884    UP000007062    UP000092462    UP000075885    UP000075880    UP000007266    UP000095300    UP000075920    UP000027135    UP000075883    UP000037069    UP000235965    UP000076408    UP000030765    UP000075900    UP000000673    UP000095301    UP000092443    UP000092460    UP000091820    UP000078200    UP000092444    UP000092445    UP000001070    UP000079169    UP000008744    UP000019118    UP000036403    UP000008792    UP000092553    UP000001819    UP000183832    UP000268350    UP000007801    UP000192223    UP000000803    UP000015103    UP000053097    UP000009192    UP000279307    UP000007798    UP000192221    UP000215335    UP000002358    UP000008711    UP000076502    UP000002282    UP000000311    UP000001292    UP000075809    UP000000305    UP000000304   

PRIDE

Q9U8D0    Q9VC52   

Pfam

PF01593   Amino_oxidase

Interpro

IPR004572   Protoporphyrinogen_oxidase        + More
IPR002937   Amino_oxidase       
IPR036188   FAD/NAD-bd_sf       

SUPFAM

SSF51905   SSF51905       

Gene 3D

3.50.50.60    

ProteinModelPortal

A0A0L7L830   A0A212EUU5   A0A3S2LWV7   A0A194QIV2   A0A0N0PEK3   A0A2A4ITR2   + More
A0A2H1WFD0   A0A1E1WFJ7   B0WEW7   A0A2P8XBA8   Q0IFY9   A0A1Q3F4X0   A0A182USH9   A0A1S4F5S5   A0A182GQK5   A0A182K861   A0A182KXY4   A0A182QLW1   A0A182I933   A0A182WVF4   A0A182F8E6   A0A182TPW0   A0A182NCK9   Q7PQE8   A0A1B0GNK9   A0A182PU01   A0A182JGV6   D6W9X5   A0A1I8QCQ9   A0A182W2Z5   A0A067QVF3   A0A182M9Q0   A0A0L0C968   A0A2J7RIM2   A0A182YEV2   A0A336KLR4   A0A084WR34   A0A182R8D3   W5JL42   T1PBF1   A0A1I8N0G2   W8BF45   A0A1A9XMX3   A0A1B0BYN3   A0A1A9WC25   A0A1A9UQ46   A0A1B6ID66   A0A1B0G1C1   A0A1B6L6C7   A0A1B6GAE0   D3TPT8   A0A1B0A8U7   B4JEJ4   A0A034WCU1   A0A0A1WVJ5   A0A0K8V4B8   A0A1S3D9S5   B4GPF6   N6U8I4   A0A0J7L3P6   B4LW33   A0A0M4ENR0   Q29BZ1   A0A1J1HVC6   A0A3B0JG34   Q9U8D0   B3M044   J3JYB3   A0A1W4W2S9   Q9VC52   A0A1Y1N1Y6   A0A069DTX3   A0A2R7X504   A0A023EZE1   A0A0P4VSK0   T1HLY0   A0A026WES5   A0A0M4EPB7   A0A1B6CEV5   B4K513   A0A3L8E463   A0A0A9YYJ2   A0A0V0GBX7   B4N8T6   A0A1W4W220   A0A0C9R5A1   A0A232F9I7   K7IR22   B3P704   I3RSG1   A0A154PPL3   B4PVR1   E2AU30   B4HH53   A0A151WP02   E9GIC4   B4QTQ6  

PDB

3NKS     E-value=8.39703e-78,     Score=739

KEGG

101740744    K00231 protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15] | (RefSeq) protoporph

PATHWAY

00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004729   GO:0005743   GO:0006782   GO:0006783   GO:0016491   GO:0005739   GO:0031304   GO:0006779   GO:0000220   GO:0016020   GO:0008270   GO:0006511   GO:0005525   GO:0003824   GO:0055114  

Subcellular location

Mitochondrion inner membrane  

Length:

427

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01754

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00440

outside

1  -  427

 

 

Pi

221.116796

Theta

196.553401

Tajima's D

0.454041

CLR

0

CSRT

0.506774661266937

Interpretation

Uncertain