Gene

KWMTBOMO05345  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002531

Annotation

PREDICTED:_angiotensin-converting_enzyme_[Bombyx_mori]

Location

Bomo_Chr9(+):15209366-15219571      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 1.641

CDS

ATGGAGCGAGGTTCCTCAGCGCCGTGGACTCATATATTACAAGAGGCCATAGGTGAATCCCGACTAAACGGGGAAGCCATGAGGGACTACTTCCGTCCTCTTGAAGATTGGCTCAGCAGCGAGAACCTTCGTACCGGAGAATTTTTAGGTTGGAGCTACGACGGAGATTATTGTAAATTTAGCATTGAAACCGCTGGTCTCCAAGTCTACGGAGGGTTCTACAATGCTGCTCAACGCCACTATGACGTCACCACTTTCATAGCACTGTTTGTGACATCAGCGCTCGTGACCATAGCTTTCAGATACAGATAG

Protein

MERGSSAPWTHILQEAIGESRLNGEAMRDYFRPLEDWLSSENLRTGEFLGWSYDGDYCKFSIETAGLQVYGGFYNAAQRHYDVTTFIALFVTSALVTIAFRYR

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.

Feature

chain  Angiotensin-converting enzyme

Uniprot

H9IZ46   A0A2H1V554   A0A194QJ84   A0A0N1IQ04   I4DKT3   A0A1E1W243   + More
A0A212EUU6   A0A139WAU4   A0A182HRW6   A0A182VC25   Q170A2   A0A023EH45   A0A182KU16   A0A182XN95   A0A088AG99   A0A182KF28   A0A1A9WU25   A0A182SIC8   A0A182Y0P3   A0A182Q046   B0WR97   E1ZZW1   A0A182WGK0   A0A0M9AB65   A0A182NBS1   A0A182F2V3   A0A182PQ29   A0A182U3P9   A0A336MW96   A0A195AUK2   A0A182MFL0   A0A1Y1M039   A0A182J8Z9   A0A1B6KA09   A0A1B0FHA4   A0A2M4BCM7   A0A2M4BCK2   A0A2M4BDM0   A0A336LW36   A0A2M3ZE07   A0A1A9VXC8   A0A1B0EXF1   A0A1B6E302   A0A084WU13   Q7Q1J9   A0A1A9XCY7   A0A232FC23   A0A1I8MMQ6   A0A1B0B0R0   A0A2M3Z1D4   A0A1B6JKF6   A0A1A9ZH47   A0A182R3U4   A0A154PMJ3   A0A1B0CG79   A0A1B6DUB7   A0A158P0W6   A0A0L7QVQ3   X1XB53   J9K4P5   A0A023F3X6   A0A0C9RD41   E2CAC6   A0A151J1J4   A0A0Q5WJG2   A0A2S2P868   A0A0Q9X021   A0A0L0BM31   A0A2H8TCU4   A0A0C9RBF0   A0A3B0JNP4   A0A151WW54   A0A1J1IC50   A0A3L8DDW7   A0A026VXF5   A0A3Q0IXC2   A0A1B6GNU4   A0A2K9Y420   B4GX34   B3MN04   B5DJZ6   K7IXA0   A0A0A9YC73   B4KEM1   A0A0K8T5T2   A0A1I8QEP7   A0A0M4ER64   T1HCD3   B4JCZ2   B4M8N3   B4Q586   B4P0G1   B4HXC1   Q8SXX2   A0A2S2PXK3   A0A0J9R277   A0A034W707   A0A0A1WX95   A0A1W4VWU8   A0A0A1XT46  

EC Number

3.4.-.-

Pubmed

19121390    26354079    22651552    22118469    18362917    19820115    + More
17510324    24945155    20966253    25244985    20798317    28004739    24438588    12364791    28648823    25315136    21347285    25474469    17994087    26108605    30249741    24508170    15632085    20075255    25401762    18057021    26823975    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    25348373    25830018   

EMBL

BABH01011134    BABH01011135    BABH01011136    ODYU01000726    SOQ35958.1    KQ458714    + More
KPJ05454.1    KQ459934    KPJ19250.1    AK401901    BAM18523.1    GDQN01010050    JAT81004.1    AGBW02012297    OWR45268.1    KQ971380    KYB25027.1    APCN01001772    CH477477    EAT40290.1    GAPW01005444    JAC08154.1    AXCN02000686    DS232053    EDS33281.1    GL435530    EFN73272.1    KQ435706    KOX80236.1    UFQT01002046    SSX32517.1    KQ976738    KYM75737.1    AXCM01001095    GEZM01044998    JAV77990.1    GEBQ01031706    GEBQ01013511    JAT08271.1    JAT26466.1    CCAG010018550    GGFJ01001639    MBW50780.1    GGFJ01001638    MBW50779.1    GGFJ01001966    MBW51107.1    UFQT01000241    SSX22262.1    GGFM01005960    MBW26711.1    AJVK01005623    GEDC01004986    JAS32312.1    ATLV01026973    ATLV01026974    ATLV01026975    ATLV01026976    ATLV01026977    ATLV01026978    ATLV01026979    ATLV01026980    ATLV01026981    ATLV01026982    KE525421    KFB53707.1    AAAB01008980    EAA14517.3    NNAY01000493    OXU28013.1    JXJN01006807    GGFM01001578    MBW22329.1    GECU01033802    GECU01026139    GECU01008087    GECU01005368    JAS73904.1    JAS81567.1    JAS99619.1    JAT02339.1    KQ434980    KZC13072.1    AJWK01010816    AJWK01010817    AJWK01010818    GEDC01008045    JAS29253.1    ADTU01005878    ADTU01005879    ADTU01005880    ADTU01005881    ADTU01005882    KQ414726    KOC62616.1    ABLF02004656    ABLF02014387    GBBI01002586    JAC16126.1    GBYB01014509    JAG84276.1    GL453975    EFN75092.1    KQ980514    KYN15766.1    CH954177    KQS70457.1    GGMR01012953    MBY25572.1    CH963857    KRF98310.1    JRES01001649    KNC21180.1    GFXV01000118    MBW11923.1    GBYB01013809    JAG83576.1    OUUW01000006    SPP82513.1    KQ982691    KYQ52124.1    CVRI01000044    CRK96558.1    QOIP01000009    RLU18657.1    KK107622    EZA48457.1    GECZ01014580    GECZ01005674    JAS55189.1    JAS64095.1    KY612467    AUW14597.1    CH479195    EDW27361.1    CH902620    EDV31982.2    CH379061    EDY70621.1    AAZX01008641    AAZX01009269    GBHO01013830    GBHO01013828    JAG29774.1    JAG29776.1    CH933807    EDW11900.1    KRG02965.1    GBRD01005048    GBRD01005045    GDHC01019599    GDHC01011567    JAG60776.1    JAP99029.1    JAQ07062.1    CP012523    ALC39612.1    ACPB03002121    CH916368    EDW03231.1    CH940654    EDW57559.1    CM000361    EDX04992.1    CM000157    EDW88955.1    CH480818    EDW51701.1    AY075532    AE014134    AAL68339.1    ABC65898.1    GGMS01000887    MBY70090.1    CM002910    KMY90188.1    GAKP01009032    GAKP01009031    JAC49920.1    GBXI01010820    JAD03472.1    GBXI01000177    JAD14115.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000007266    UP000075840    + More
UP000075903    UP000008820    UP000075882    UP000076407    UP000005203    UP000075881    UP000091820    UP000075901    UP000076408    UP000075886    UP000002320    UP000000311    UP000075920    UP000053105    UP000075884    UP000069272    UP000075885    UP000075902    UP000078540    UP000075883    UP000075880    UP000092444    UP000078200    UP000092462    UP000030765    UP000007062    UP000092443    UP000215335    UP000095301    UP000092460    UP000092445    UP000075900    UP000076502    UP000092461    UP000005205    UP000053825    UP000007819    UP000008237    UP000078492    UP000008711    UP000007798    UP000037069    UP000268350    UP000075809    UP000183832    UP000279307    UP000053097    UP000079169    UP000008744    UP000007801    UP000001819    UP000002358    UP000009192    UP000095300    UP000092553    UP000015103    UP000001070    UP000008792    UP000000304    UP000002282    UP000001292    UP000000803    UP000192221   

PRIDE

H9IZ46    Q8SXX2   

Pfam

PF01401   Peptidase_M2

Interpro

IPR001548   Peptidase_M2        + More
IPR008979   Galactose-bd-like_sf       
IPR011989   ARM-like       

SUPFAM

SSF49785   SSF49785       

Gene 3D

1.25.10.10    

CDD

cd06461  M2_ACE

ProteinModelPortal

H9IZ46   A0A2H1V554   A0A194QJ84   A0A0N1IQ04   I4DKT3   A0A1E1W243   + More
A0A212EUU6   A0A139WAU4   A0A182HRW6   A0A182VC25   Q170A2   A0A023EH45   A0A182KU16   A0A182XN95   A0A088AG99   A0A182KF28   A0A1A9WU25   A0A182SIC8   A0A182Y0P3   A0A182Q046   B0WR97   E1ZZW1   A0A182WGK0   A0A0M9AB65   A0A182NBS1   A0A182F2V3   A0A182PQ29   A0A182U3P9   A0A336MW96   A0A195AUK2   A0A182MFL0   A0A1Y1M039   A0A182J8Z9   A0A1B6KA09   A0A1B0FHA4   A0A2M4BCM7   A0A2M4BCK2   A0A2M4BDM0   A0A336LW36   A0A2M3ZE07   A0A1A9VXC8   A0A1B0EXF1   A0A1B6E302   A0A084WU13   Q7Q1J9   A0A1A9XCY7   A0A232FC23   A0A1I8MMQ6   A0A1B0B0R0   A0A2M3Z1D4   A0A1B6JKF6   A0A1A9ZH47   A0A182R3U4   A0A154PMJ3   A0A1B0CG79   A0A1B6DUB7   A0A158P0W6   A0A0L7QVQ3   X1XB53   J9K4P5   A0A023F3X6   A0A0C9RD41   E2CAC6   A0A151J1J4   A0A0Q5WJG2   A0A2S2P868   A0A0Q9X021   A0A0L0BM31   A0A2H8TCU4   A0A0C9RBF0   A0A3B0JNP4   A0A151WW54   A0A1J1IC50   A0A3L8DDW7   A0A026VXF5   A0A3Q0IXC2   A0A1B6GNU4   A0A2K9Y420   B4GX34   B3MN04   B5DJZ6   K7IXA0   A0A0A9YC73   B4KEM1   A0A0K8T5T2   A0A1I8QEP7   A0A0M4ER64   T1HCD3   B4JCZ2   B4M8N3   B4Q586   B4P0G1   B4HXC1   Q8SXX2   A0A2S2PXK3   A0A0J9R277   A0A034W707   A0A0A1WX95   A0A1W4VWU8   A0A0A1XT46  

PDB

6H5W     E-value=1.7593e-07,     Score=125

KEGG

101737600    K01283 peptidyl-dipeptidase A [EC:3.4.15.1] | (RefSeq) angiotensin-converting enzyme

GO

GO:0016021   GO:0008237   GO:0008241   GO:0016020   GO:0046872   GO:0004180   GO:0008239   GO:0005615   GO:0008238   GO:0005886   GO:0006508   GO:0008270   GO:0006511   GO:0005525   GO:0016491   GO:0003824  

PANTHER

PTHR10514  

Length:

103

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.53316

Exp number, first 60 AAs:

0.00456

Total prob of N-in:

0.23205

outside

1  -  82

TMhelix

83  -  100

inside

101  -  103

 

 

Pi

6.453235

Theta

38.748016

Tajima's D

-1.502199

CLR

103.652566

CSRT

0.0595970201489925

Interpretation

Uncertain