Gene

KWMTBOMO05340

Pre Gene Modal

BGIBMGA002528

Annotation

PREDICTED:_angiotensin-converting_enzyme_[Bombyx_mori]

Location

Bomo_Chr9(+):15030286-15069359      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

Nuclear   Reliability : 1.931

CDS

ATGGCCTGTCTCACTAGGAAGTTTTCCCTATCATGGGTGCAGCTTGGCCTGGTTTTGTGCTTTATCTATTGCGCTATCGGCGTTCCGCAGTTAGACCTACCGCCGATTCCCAGTACTTCTCAAAGCGGCTATGGCCTATCTAGTACTCCATCGTCTCTCAATTCTCCCGGGAATCAGTTTGACAGGAATTATCAGTTCAGCACTGCGAGACCGAGTCCTACCAGCACGCCTGGAGTTTACCAAGTTTCCTCCACCCCGTTCAACGGAATAAGTCCGGATATAAGCAACAATGGGTATCCGAATGTTGACTATAACAGCAGAAACCCTAGTTCTACGCTCCGACCTTATGACGAAAGTAACGGAGACGACAGAATTGACATTAACAGTGATCCGAACTTCAGAAGAAACGACCCCAACTTTGTCAGGAACGACCCGAACTACGTAGGAACTAATCCGTATGATTTCAATCGGGGCGGGGATGTAAATAGTATTGATGATAGATACCGCCAAGTGAACTTGCAGCAGGTCAGAGATTTTCTGGCACAGGCTGACGATCAGGCTTCGAAGGAATGCACCAATAACGTCGCAGCGCAGTGGAACTTCGAAACAAACGTCAATGATGAAACACAGCATGCAGCGCTGGACGCCCAACAGCGCTACACATTGTTCCAGCGAGGACTATGGGAGGCCGCACAGCAAATACCTCGTGGAGCTATCAGGGACTTTCCGACCTTCAGACAACTCCGGCTTCTGTCTATTATAGGACCTGCAGCTCTACCCCCTGATCAACTGGATAGGTACAACCGCATAATAAACGACATGCTGGCTGTTTACAATACTGCCGAGGTCTGCGCCTACAACGAGCCATTCAAGTGTGGTCTCCATCTCCAACCGGAGCTGCAGTACATCATGTCCCACTCCAGAGACTGGGACGAACTTCAGCACATCTGGACCGAGTGGAGGAGGAATACTGGTAGAAGAGTACGGGATTTATACGAGCAGTTGGTTGATTTGACCAATCAGGCAGCCAGATTGAATAATTTTACTGACGCATCCGCGTACTGGATGTTTCCTTACGAGACCTCAAACATGCGGCAGGAGGTCGATGACGTCTGGCAGCAGATCAAGCCCCTTTATGACCAGCTTCACGCCTACGTTCGTCGTCGTCTGCGAGAAGCCTACGGTCCTGAGAGAATCTCCAGATCGGCTCCGTTACCAGCCCACATCCTGGGAGACATGTGGGGACAGAGCTGGTCGGGTATCGTGCCTTTTACCCTTCCTTACCCTGGGAAAAACTTGCTAGATGTCTCTCAGGAAATGGCGAAGCAGGGTTTCACTCCACTCACAATGTTTCAATTAGCTGAAGAGTACTTCGTGTCCATGAATATGTCTGCCATGCCTCCTGACTTTTGGGCCCTAAGCGTGTTGGACCAACCTCCGGACAGACACATCCACTGCCAGCCTTCTGCTTGGGACTTTTGCAATAAGCACGACTATCGCATCAAAATGTGCACACACGTGGACATGAAGGATCTGGTGACGGCGCATCATGAGATGGCGCACATCGAATATTTCCTCGCCTACAGGAATCAGCCGAAAGTCTTCCGTGATGGTGCTAATCCAGGTTTCCACGAAGCTATTGGTGAGACAATAGCACTGTCAGTTGGATCCCCTCGTCACCTGCAAACCCTAGGCCTGGTTCAACGTTCGGTAGACGACACAGCCCACAACACGAACTTCCTGTTCACCCAAGCTATGGACAAGTTAGCGTTTCTTCCGTTCGCGCTGGTGATGGACAGGTGGCGTTGGGACGTGTTCACAGGAGACGTCCGCAAGGAGCAGTACAATTGCCATTGGTGGAGATTAAGGGAGCAGTACCAAGGTGTGAAGCCTCCCGTGCTGCGTTCCGAGCTGGACTTCGACCCTGGATCCAAGTACCACATACCGGCCAACATACCCTACATAAGGTCAGTTTAG

Protein

MACLTRKFSLSWVQLGLVLCFIYCAIGVPQLDLPPIPSTSQSGYGLSSTPSSLNSPGNQFDRNYQFSTARPSPTSTPGVYQVSSTPFNGISPDISNNGYPNVDYNSRNPSSTLRPYDESNGDDRIDINSDPNFRRNDPNFVRNDPNYVGTNPYDFNRGGDVNSIDDRYRQVNLQQVRDFLAQADDQASKECTNNVAAQWNFETNVNDETQHAALDAQQRYTLFQRGLWEAAQQIPRGAIRDFPTFRQLRLLSIIGPAALPPDQLDRYNRIINDMLAVYNTAEVCAYNEPFKCGLHLQPELQYIMSHSRDWDELQHIWTEWRRNTGRRVRDLYEQLVDLTNQAARLNNFTDASAYWMFPYETSNMRQEVDDVWQQIKPLYDQLHAYVRRRLREAYGPERISRSAPLPAHILGDMWGQSWSGIVPFTLPYPGKNLLDVSQEMAKQGFTPLTMFQLAEEYFVSMNMSAMPPDFWALSVLDQPPDRHIHCQPSAWDFCNKHDYRIKMCTHVDMKDLVTAHHEMAHIEYFLAYRNQPKVFRDGANPGFHEAIGETIALSVGSPRHLQTLGLVQRSVDDTAHNTNFLFTQAMDKLAFLPFALVMDRWRWDVFTGDVRKEQYNCHWWRLREQYQGVKPPVLRSELDFDPGSKYHIPANIPYIRSV

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.

Feature

chain  Angiotensin-converting enzyme

Uniprot

A0A212F3F9   A0A3S2TLH5   A0A2A4IVE5   A0A0N1IC85   A0A194QJ89   A0A182NBR7   + More
A0A2M4CGD1   W5JF67   A0A1Y9G9G1   A0A2M4BCK2   A0A2M4BCM7   A0A2M4BDM0   A0A182R3U4   A0A182Y0N9   A0A2M3Z1D4   A0A2M3ZE07   A0A182WGJ6   A0A182QWK5   A0A182K2I1   A0A182XN91   A0A182LZL0   A0A182JJ88   A0A182U8D7   A0A182UXG9   A0A240PL25   A0A182HRX0   Q7Q1J9   A0A182GI45   A0A1B6DUB7   A0A182GQM7   Q17HJ9   A0A182KU23   A0A1B6KA09   A0A1B6GNU4   A0A2J7QU96   A0A139WAY6   B0WR91   A0A1Y1M039   U4TXW0   A0A1J1IC50   A0A1B0GNY6   A0A084WU13   A0A2K9Y420   A0A2H8TCU4   A0A2S2PGF5   J9K345   A0A2S2PBL3   A0A2S2PXK3   A0A088AG98   A0A3Q0IXC2   A0A026VXF5   A0A3L8DDW7   E2CAC6   E0VYZ7   A0A158P0W6   A0A154PMJ3   A0A336N2A5   A0A336MZK1   A0A0C9RBF0   A0A0K8T5T2   A0A195CXY5   A0A1B0CG74   A0A0L7QVQ3   A0A310SFD5   A0A182SJM2   A0A023F3X6   K7IXA0   A0A151WW54   A0A0L0BM21   A0A1A9WU17   A0A1I8QEP7   Q8SXX2   B3MN04   B3NAA9   B4JCZ2   A0A3B0JNP4   B5DJZ6   B4HXC1   A0A0J9R277   A0A1A9ZH25   B4P0G1   A0A151J1J4   B4GX34   A0A1W4VWU8   A0A1B0B0S6   A0A1A9XD02   A0A0M4ECZ1   A0A232FBL4   A0A0M4ER64   A0A0M4E948   B4KEM1   B4M8N3   E1ZZV7   A0A0A1XT46   A0A0A1WX95  

EC Number

3.4.-.-

Pubmed

22118469    26354079    20920257    23761445    25244985    12364791    + More
26483478    17510324    20966253    18362917    19820115    28004739    23537049    24438588    24508170    30249741    20798317    20566863    21347285    26823975    25474469    20075255    26108605    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17994087    15632085    22936249    17550304    28648823    18057021    25830018   

EMBL

AGBW02010565    OWR48271.1    RSAL01000066    RVE49364.1    NWSH01006011    PCG63755.1    + More
KQ459934    KPJ19244.1    KQ458714    KPJ05459.1    GGFL01000195    MBW64373.1    ADMH02001324    ETN63012.1    GGFJ01001638    MBW50779.1    GGFJ01001639    MBW50780.1    GGFJ01001966    MBW51107.1    GGFM01001578    MBW22329.1    GGFM01005960    MBW26711.1    AXCN02000684    AXCM01007372    APCN01001773    AAAB01008980    EAA14517.3    JXUM01065210    JXUM01065211    JXUM01065212    KQ562335    KXJ76121.1    GEDC01008045    JAS29253.1    JXUM01016019    KQ560447    KXJ82378.1    CH477248    EAT46108.1    GEBQ01031706    GEBQ01013511    JAT08271.1    JAT26466.1    GECZ01014580    GECZ01005674    JAS55189.1    JAS64095.1    NEVH01011186    PNF32150.1    KQ971380    KYB25031.1    DS232053    EDS33275.1    GEZM01044998    JAV77990.1    KB631815    ERL86439.1    CVRI01000044    CRK96558.1    AJVK01005614    ATLV01026973    ATLV01026974    ATLV01026975    ATLV01026976    ATLV01026977    ATLV01026978    ATLV01026979    ATLV01026980    ATLV01026981    ATLV01026982    KE525421    KFB53707.1    KY612467    AUW14597.1    GFXV01000118    MBW11923.1    GGMR01015669    MBY28288.1    ABLF02009599    ABLF02014513    GGMR01013687    MBY26306.1    GGMS01000887    MBY70090.1    KK107622    EZA48457.1    QOIP01000009    RLU18657.1    GL453975    EFN75092.1    DS235848    EEB18603.1    ADTU01005878    ADTU01005879    ADTU01005880    ADTU01005881    ADTU01005882    KQ434980    KZC13072.1    UFQT01002046    SSX32518.1    UFQS01003120    UFQT01003120    SSX15234.1    SSX34609.1    GBYB01013809    JAG83576.1    GBRD01005048    GBRD01005045    GDHC01019599    GDHC01011567    JAG60776.1    JAP99029.1    JAQ07062.1    KQ977141    KYN05442.1    AJWK01010804    AJWK01010805    KQ414726    KOC62616.1    KQ777390    OAD52110.1    GBBI01002586    JAC16126.1    AAZX01008641    AAZX01009269    KQ982691    KYQ52124.1    JRES01001649    KNC21170.1    AY075532    AE014134    AAL68339.1    ABC65898.1    CH902620    EDV31982.2    CH954177    EDV58611.2    CH916368    EDW03231.1    OUUW01000006    SPP82513.1    CH379061    EDY70621.1    CH480818    EDW51701.1    CM002910    KMY90188.1    CM000157    EDW88955.1    KQ980514    KYN15766.1    CH479195    EDW27361.1    JXJN01006810    JXJN01006811    CP012523    ALC39572.1    NNAY01000493    OXU28012.1    ALC39612.1    ALC39577.1    CH933807    EDW11900.1    KRG02965.1    CH940654    EDW57559.1    GL435530    EFN73268.1    GBXI01000177    JAD14115.1    GBXI01010820    JAD03472.1   

Proteomes

UP000007151    UP000283053    UP000218220    UP000053240    UP000053268    UP000075884    + More
UP000000673    UP000069272    UP000075900    UP000076408    UP000075920    UP000075886    UP000075881    UP000076407    UP000075883    UP000075880    UP000075902    UP000075903    UP000075885    UP000075840    UP000007062    UP000069940    UP000249989    UP000008820    UP000075882    UP000235965    UP000007266    UP000002320    UP000030742    UP000183832    UP000092462    UP000030765    UP000007819    UP000005203    UP000079169    UP000053097    UP000279307    UP000008237    UP000009046    UP000005205    UP000076502    UP000078542    UP000092461    UP000053825    UP000075901    UP000002358    UP000075809    UP000037069    UP000091820    UP000095300    UP000000803    UP000007801    UP000008711    UP000001070    UP000268350    UP000001819    UP000001292    UP000092445    UP000002282    UP000078492    UP000008744    UP000192221    UP000092460    UP000092443    UP000092553    UP000215335    UP000009192    UP000008792    UP000000311   

PRIDE

Q8SXX2   

Pfam

PF01401   Peptidase_M2        + More
PF16009   DUF4779

Interpro

IPR001548   Peptidase_M2        + More
IPR011989   ARM-like       
IPR008979   Galactose-bd-like_sf       
IPR031959   DUF4779       

SUPFAM

SSF49785   SSF49785       

Gene 3D

1.25.10.10    

CDD

cd06461  M2_ACE

ProteinModelPortal

A0A212F3F9   A0A3S2TLH5   A0A2A4IVE5   A0A0N1IC85   A0A194QJ89   A0A182NBR7   + More
A0A2M4CGD1   W5JF67   A0A1Y9G9G1   A0A2M4BCK2   A0A2M4BCM7   A0A2M4BDM0   A0A182R3U4   A0A182Y0N9   A0A2M3Z1D4   A0A2M3ZE07   A0A182WGJ6   A0A182QWK5   A0A182K2I1   A0A182XN91   A0A182LZL0   A0A182JJ88   A0A182U8D7   A0A182UXG9   A0A240PL25   A0A182HRX0   Q7Q1J9   A0A182GI45   A0A1B6DUB7   A0A182GQM7   Q17HJ9   A0A182KU23   A0A1B6KA09   A0A1B6GNU4   A0A2J7QU96   A0A139WAY6   B0WR91   A0A1Y1M039   U4TXW0   A0A1J1IC50   A0A1B0GNY6   A0A084WU13   A0A2K9Y420   A0A2H8TCU4   A0A2S2PGF5   J9K345   A0A2S2PBL3   A0A2S2PXK3   A0A088AG98   A0A3Q0IXC2   A0A026VXF5   A0A3L8DDW7   E2CAC6   E0VYZ7   A0A158P0W6   A0A154PMJ3   A0A336N2A5   A0A336MZK1   A0A0C9RBF0   A0A0K8T5T2   A0A195CXY5   A0A1B0CG74   A0A0L7QVQ3   A0A310SFD5   A0A182SJM2   A0A023F3X6   K7IXA0   A0A151WW54   A0A0L0BM21   A0A1A9WU17   A0A1I8QEP7   Q8SXX2   B3MN04   B3NAA9   B4JCZ2   A0A3B0JNP4   B5DJZ6   B4HXC1   A0A0J9R277   A0A1A9ZH25   B4P0G1   A0A151J1J4   B4GX34   A0A1W4VWU8   A0A1B0B0S6   A0A1A9XD02   A0A0M4ECZ1   A0A232FBL4   A0A0M4ER64   A0A0M4E948   B4KEM1   B4M8N3   E1ZZV7   A0A0A1XT46   A0A0A1WX95  

PDB

5A2R     E-value=4.48679e-122,     Score=1123

KEGG

101737600    K01283 peptidyl-dipeptidase A [EC:3.4.15.1] | (RefSeq) angiotensin-converting enzyme

GO

GO:0016020   GO:0046872   GO:0008241   GO:0008237   GO:0004180   GO:0016021   GO:0005886   GO:0008239   GO:0008238   GO:0005615   GO:0006508   GO:0008270   GO:0006511   GO:0005525   GO:0016491   GO:0003824  

PANTHER

PTHR10514  

SignalP

Position:   1 - 27,         Likelihood:  0.764362

 

 

Length:

658

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.34941

Exp number, first 60 AAs:

18.34409

Total prob of N-in:

0.85621

POSSIBLE N-term signal

sequence

inside

1  -  8

TMhelix

9  -  31

outside

32  -  658

 

 

Pi

202.740497

Theta

154.842638

Tajima's D

1.125536

CLR

0.633938

CSRT

0.696815159242038

Interpretation

Uncertain