Gene

KWMTBOMO05339  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002527

Annotation

male_reproductive_organ_angiotensin-converting_enzyme-related_protein_2_precursor_[Bombyx_mori]

Location

Bomo_Chr9(+):15004306-15020380      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

Cytoplasmic   Reliability : 3.183

CDS

ATGATAATGAAGATTATCGGGGAGCTCGCCCTTCTGGGTGCTATCGCGTCAGTCTTCCTGGTAGCAGCCCAGGGTCGGGCAGCAGAAAGAGCTGCAGAGGAATCCGCTGGGCGAGATTACGTGAGGACTTTGGACGAACAGACTTCTCGGCTCAGGAACAAGAAAACGATTGCCTCTTGGGACTATGAGACGAATTTGACAGTCCATAACGAACAGAAATTGTTACAAGTATCCTTAGAGGTGGCAAGCGAAACGAAGGAATACTGGAAGGAAACCATGAGCTACCTCTGGCACGAGTTCGAAGACCCGGACCTGAAGAGGATGTTCAAGAAATACACGGAGCTGGGCACATCAGCTCTACCCGAGGATTTGAATCAGAGATTGATCGTGGCCATCAATAGCATGCAGTCAACTTACGCTAAGGCAACGATCTGTGATTATAATAATCGGACTAAATGTGATTTGCATGTTGAACCTGAAATCACAAACATTTTTGCGACAAGCAGCGACGCTGAAGAACTCAAGTACACATGGCTTGAATGGCATAAGGCAGCGGGTGCTCCATCGAAGAGTAACTTCACCGAGTACGTTCAAATGGAGAACGAGGCTGCCAAATTAAATGGTTACGACACTGTGGCCGAATGGTGGCTTAGTGAATATGAAGCTACAGACAGCGAGGACCAGTTCGCAGCGCTCTGGGCGCAAATCAAACCGCTCTATGAACAGATTCATGCGTACGTCAGAGGGCATCTTCGTGTGAAGTATGGAGAAGAAGTCGTGCCGAAGAAAGGACCCATTCCAGCTCATTTGTTAGGTAACATTTGGGCCCAAACTTGGGGTAACGTTGAAAAATTCACAAGGCCGTATCCGGATAAGACCGATATTGATGTAACTGCCGCGCTCATTGCACAGAATTACACAGCCCTTAAGATGTTTAAGACAGCAGAGGAGTTTTTTACGTCATTGGATTTATCCCCAATGCCAGAGTTGTTCTGGGAAAGATCCATCTTAGAGAAACCAACTGATGGAAGAGAAATGGTCTGCCATGCTTCTGCTTGGGACTTTTTCGACGGTGAAGATTTCAGAATCCGTCAATGCACAACCATCACGGACGCGTTCTTCAAGACGACCCACCACGAAATGGGTCACATACAATACTACTTGCAGTACAAGGATCAGCCGGTGATCTACAGGGCTGGAGCTAATCCAGGTTTTCACGAAGCAGTTGGTGACGTCATCGCACTGTCGGTGGCAACGCCGAAACATTTACGGGTGATGGGGCTTCTCGAGGATGGACCAGAAGATTTGGAATCTAACATTAATCAGCTTTACAAAATGGGTCTGGACAAGATAGTTTTCTTACCATTCGGCTATCTCCTCGATCTCTTCCGTTATGGCGTCTTCCGAGGAACTACCACAGTTGACGACTACAATTGTCACTTCTGGCAACTAAGAGAGTCCTTGCAGGGCGTGGAACCTCCGGCGCCACGAAGCGAAGCGGACTTTGATCCTGCTGCAAAGTACCATATAGCTGCAGATGTGGAATACATGAGATACTATATCTCTTACATTATCCAGTTTCAATTCCATCGTTCGTTATGCCAGCTTGCCGGGGAGTACGCGGTTGGCGACTCCAGCAGGCTGCTCTCAAACTGCGATATTTACAACAGCACGGCGGCAGGAAACGCTCTCGGCAAAATGCTGCAATTGGGTTCTTCGAAGCCGTGGCCCGACGCGATGGAAGCGATAACTGGACAAAGGTTCATGGATGCCAGCGGCGTCCTGGAGTACTTCCAGCCTCTATACGATTGGCTCAAGGCCGAGAACGAACGAAATGGAGAATTTGTCGGTTGGGAGCCTAGTACCGTCCAATTTTGTACTCCAAACCAAAGAGCAGCGATGGAAGCGACCGGCTTTAACAAGAGATTGAAGAAATATGCAGCTCTATAG

Protein

MIMKIIGELALLGAIASVFLVAAQGRAAERAAEESAGRDYVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHEFEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGWEPSTVQFCTPNQRAAMEATGFNKRLKKYAAL

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.

Feature

chain  Angiotensin-converting enzyme

Uniprot

H9IZ42   B9X255   B0LJE2   A0A2H1VQG9   A0A212F3H8   A0A3S2M2A7   + More
A0A1E1W694   A0A0N0PEJ7   A0A2A4IWT8   A0A0L7LS53   H9IZ41   Q9NDS8   A0A212F3I4   A0A194QIX2   A0A3S2LLM4   A0A0N1ICA6   A0A2H1V7I0   I4DJQ5   E0VYZ8   A0A0U3KDL0   A0A1Q3FRW0   A0A2J7QUF6   A0A2J7QUE9   A0A1S4G6D0   J9E9A1   A0A1Y1NHL6   A0A1Q3FRM3   Q6RX62   A0A0N0BEI9   A0A1I9WL53   A0A023EUI3   A0A023EVK4   A0A023EVB9   A0A023EXC8   A0A087ZRC1   A0A310SP14   M9PM20   B0WR90   W5JI94   V9IK38   A0A2A3E9I4   A0A026X3N5   D6X4L0   A0A182GI44   A0A1S6J0Y7   A0A2M4AK25   A0A2M4AJS0   A0A2M4AK82   A0A2M4AJQ6   A0A2M4DP36   T1DLB0   A0A182XN90   A0A1Y9G9N3   A0A0L7QKN3   A0A2J7QUG0   A0NFV1   A0A2C9GR30   A0A2M4BH35   A0A2M4BH75   A0A2M4BH14   A0A182Y0N8   A0A2M4BGX1   A0A2M4BHR7   A0A182LUT3   A0A1Y9G8A7   A0A182QDG1   A0A154PK20   A0A084VR60   A0A1I8JUB7   A0A182GQM8   A0A1Y9G8E7   A0A084VR61   A0A240PM54   A0A182WGJ2   Q7PM22   A0A1Q3FFN8   A0A1Q3FFN2   A0A1B6EFN8   A0NFV2   A0A240PPV9   A0A182JL55   A0A1Q3FG20   A0A182NBR7   A0A1B6C745   A0A2C9GRB4   A0A1B6DC58   A0A1Q3FG39   Q5WPT4   A0A1L8DR16   A0A182QUK4   A0A2S2QGZ9   T1EB36   A0A182J606   A0A336LZ65   J9K7M4   A0A182Y0N9   A0A182TYM7   A0A1Y9G9F7   A0A1I8JUD0   A0A182KU25  

EC Number

3.4.-.-

Pubmed

19121390    22118469    26354079    26227816    11102839    22651552    + More
20566863    26694822    17510324    28004739    27538518    24945155    25581109    20920257    23761445    24508170    30249741    18362917    19820115    26483478    27414796    12364791    14747013    17210077    25244985    24438588    15371479    20966253   

EMBL

BABH01011115    BABH01011116    AB485781    BAH23569.1    EU170161    ABW34729.1    + More
ODYU01003823    SOQ43060.1    AGBW02010565    OWR48272.1    RSAL01000066    RVE49365.1    GDQN01008554    JAT82500.1    KQ459934    KPJ19243.1    NWSH01006011    PCG63754.1    JTDY01000210    KOB78277.1    AB026110    AB485780    BAA97657.1    BAH23568.1    OWR48273.1    KQ458714    KPJ05462.1    RVE49366.1    KQ461002    KPJ10041.1    ODYU01000895    SOQ36342.1    AK401523    BAM18145.1    DS235848    EEB18604.1    KU218691    ALX00071.1    GFDL01004760    JAV30285.1    NEVH01011186    PNF32210.1    PNF32208.1    CH477248    EJY57431.1    GEZM01002421    JAV97269.1    GFDL01004795    JAV30250.1    AY487174    AAR85358.1    KQ435827    KOX71968.1    KU932237    APA33873.1    GAPW01000528    JAC13070.1    GAPW01000531    JAC13067.1    GAPW01000530    JAC13068.1    GAPW01000529    JAC13069.1    KQ762196    OAD56126.1    KC437298    AGC79111.1    DS232053    EDS33274.1    ADMH02001324    ETN63008.1    JR048421    AEY60659.1    KZ288322    PBC28134.1    KK107013    QOIP01000003    EZA62925.1    RLU25153.1    KQ971380    EEZ97252.2    JXUM01065208    JXUM01065209    KQ562335    KXJ76120.1    KU764440    AQS60686.1    GGFK01007818    MBW41139.1    GGFK01007715    MBW41036.1    GGFK01007707    MBW41028.1    GGFK01007699    MBW41020.1    GGFL01015113    MBW79291.1    GAMD01000546    JAB01045.1    KQ414954    KOC59071.1    PNF32211.1    AAAB01008980    EAU76040.2    APCN01001774    GGFJ01003206    MBW52347.1    GGFJ01003160    MBW52301.1    GGFJ01003208    MBW52349.1    GGFJ01003159    MBW52300.1    GGFJ01003207    MBW52348.1    AXCM01007217    AXCN02000684    KQ434943    KZC12209.1    ATLV01015459    KE525014    KFB40454.1    JXUM01016020    JXUM01016021    KQ560447    KXJ82379.1    KFB40455.1    EAA14501.5    GFDL01008681    JAV26364.1    GFDL01008678    JAV26367.1    GEDC01000545    JAS36753.1    EAU76041.1    GFDL01008546    JAV26499.1    GEDC01028238    JAS09060.1    GEDC01024908    GEDC01014015    JAS12390.1    JAS23283.1    GFDL01008526    JAV26519.1    AY455911    AAS16911.1    GFDF01005267    JAV08817.1    GGMS01007793    MBY76996.1    GAMD01000383    JAB01208.1    UFQS01000326    UFQT01000326    SSX02915.1    SSX23282.1    ABLF02025366   

Proteomes

UP000005204    UP000007151    UP000283053    UP000053240    UP000218220    UP000037510    + More
UP000053268    UP000009046    UP000235965    UP000008820    UP000053105    UP000005203    UP000002320    UP000000673    UP000242457    UP000053097    UP000279307    UP000007266    UP000069940    UP000249989    UP000076407    UP000069272    UP000053825    UP000007062    UP000075840    UP000076408    UP000075883    UP000075886    UP000076502    UP000030765    UP000075900    UP000075885    UP000075920    UP000075880    UP000075884    UP000007819    UP000075902    UP000075882   

PRIDE

H9IZ42    B9X255    H9IZ41    Q9NDS8   

Pfam

PF01401   Peptidase_M2        + More
PF05160   DSS1_SEM1

Interpro

IPR001548   Peptidase_M2        + More
IPR011989   ARM-like       
IPR007834   DSS1_SEM1       

Gene 3D

1.25.10.10    

CDD

cd06461  M2_ACE

ProteinModelPortal

H9IZ42   B9X255   B0LJE2   A0A2H1VQG9   A0A212F3H8   A0A3S2M2A7   + More
A0A1E1W694   A0A0N0PEJ7   A0A2A4IWT8   A0A0L7LS53   H9IZ41   Q9NDS8   A0A212F3I4   A0A194QIX2   A0A3S2LLM4   A0A0N1ICA6   A0A2H1V7I0   I4DJQ5   E0VYZ8   A0A0U3KDL0   A0A1Q3FRW0   A0A2J7QUF6   A0A2J7QUE9   A0A1S4G6D0   J9E9A1   A0A1Y1NHL6   A0A1Q3FRM3   Q6RX62   A0A0N0BEI9   A0A1I9WL53   A0A023EUI3   A0A023EVK4   A0A023EVB9   A0A023EXC8   A0A087ZRC1   A0A310SP14   M9PM20   B0WR90   W5JI94   V9IK38   A0A2A3E9I4   A0A026X3N5   D6X4L0   A0A182GI44   A0A1S6J0Y7   A0A2M4AK25   A0A2M4AJS0   A0A2M4AK82   A0A2M4AJQ6   A0A2M4DP36   T1DLB0   A0A182XN90   A0A1Y9G9N3   A0A0L7QKN3   A0A2J7QUG0   A0NFV1   A0A2C9GR30   A0A2M4BH35   A0A2M4BH75   A0A2M4BH14   A0A182Y0N8   A0A2M4BGX1   A0A2M4BHR7   A0A182LUT3   A0A1Y9G8A7   A0A182QDG1   A0A154PK20   A0A084VR60   A0A1I8JUB7   A0A182GQM8   A0A1Y9G8E7   A0A084VR61   A0A240PM54   A0A182WGJ2   Q7PM22   A0A1Q3FFN8   A0A1Q3FFN2   A0A1B6EFN8   A0NFV2   A0A240PPV9   A0A182JL55   A0A1Q3FG20   A0A182NBR7   A0A1B6C745   A0A2C9GRB4   A0A1B6DC58   A0A1Q3FG39   Q5WPT4   A0A1L8DR16   A0A182QUK4   A0A2S2QGZ9   T1EB36   A0A182J606   A0A336LZ65   J9K7M4   A0A182Y0N9   A0A182TYM7   A0A1Y9G9F7   A0A1I8JUD0   A0A182KU25  

PDB

5A2R     E-value=0,     Score=1632

KEGG

101739932    K01283 peptidyl-dipeptidase A [EC:3.4.15.1] | (RefSeq) angiotensin-converting enzyme-like

GO

GO:0016020   GO:0008237   GO:0004180   GO:0046872   GO:0008241   GO:0016021   GO:0005886   GO:0005615   GO:0008238   GO:0008239   GO:0006406   GO:0043248   GO:0008541   GO:0006508   GO:0008270   GO:0006511   GO:0005525   GO:0016491   GO:0003824  

PANTHER

PTHR10514  

SignalP

Position:   1 - 27,         Likelihood:  0.602732

 

 

Length:

649

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.55305

Exp number, first 60 AAs:

12.10793

Total prob of N-in:

0.60419

POSSIBLE N-term signal

sequence

outside

1  -  649

 

 

Pi

269.074152

Theta

137.055457

Tajima's D

2.988655

CLR

0.313824

CSRT

0.980800959952002

Interpretation

Uncertain