Gene

KWMTBOMO05327

Pre Gene Modal

BGIBMGA002524

Annotation

PREDICTED:_alkylglycerol_monooxygenase-like_[Amyelois_transitella]

Location

Bomo_Chr9(+):14419418-14453466      View in EpiBrowser

Full name

Alkylglycerol monooxygenase      

Alternative Name

Transmembrane protein 195

Location in the cell

PlasmaMembrane   Reliability : 4.538

CDS

ATGGCGGAATTCTCGTTCGCCAATGCGAGTGTCGAGAACGGTTTCTCGGATTTCGTTACGGATCATCTGAAGGGAGTTGGAAGACTTTTCTACATAAATTCCCCTCAAGACTCTATGTTTGAGAAGAAAGATGATGTGCCGAACTTTTTCAAGCAGTCATGGCCGTATTTCTTCATCTTCATGATCCTGGAGCACATCGTCCTGAGGCTGGAAGGGAAGCCAGGCGTCAGACTTAACGACGGAATCACAAGTATATCGCACGGAATCTTCCAAGAATGCGGAAGAATTATTTGGCGTGGTGCTGAGTCTTACTTGTACACGTGGATCTACACCAACTACAGATTAGTGGAGCTGCCCTGGGACAGCACGCTGACCTGGTATGCGGCAGCTCTTGGCGTCGACTTCTGCTATTACTGGATGCACAGGGCCTGCCATGAGGTCCATATACTATGGGCGCAACATCAAGTACACCACACGTCAGAAGACTTCAACATGGGCGTCGGAATACGTCAATCCGTTCTTCAAGGCTGGTGCGGATTTATATTCTACCTACCTCTGGCATTTGCCATACCACCAGCCCAGTTTGTTGTTCACCACCAGTTCAGCTACCTTTACATGTTCTGGATTCACACCGAAGCCATCAAGAGCCTTGGTCCGCTAGAATATATCCTCAACACTCCAAGTCATCATAGAGTGCATCATGGCAGCAATAAGTACTGCTTAGATGTAAACTACGGCGGAGTCCTCATCGTTTGGGACAGACTCTTCGGCACCTTTAAACCCGAAACAGATAAGATCGAGATCGTGTATGGACTAATATACAATCAACCTTCATTCAACCCTCTGTACTTACAGTCGTTCTACAATGGCTACGTGCTGGAGAAGTTCCGCAGCTATGAATCCTGGGGTGACAAGATGAGGGCTATCTTCTGGGGTCCGAGTTGGGAACCTGGTTCACCGAGACTTGGAGACGAGGACATGAAAGTTGACGTCGAAAATAGGGAAAAATACGACGTGCATTTACCAGCGTGGTGTAACGCGTACTTGGTGACTCATTACGCGGTTGTTCTGTATGGATTCTTTGAGCTTGCTTCTAGGCACATGGGCATGACACCCATCTCTGTTTTGATATTCGTCGTCTACATCATAGCATCGTTATCTGTAATCGGGATGCTGTTTGACAATTCGCGACACGCCCCTATTTTAGAAGTCCTAAGATGTTCAGCTCTGGCGTTCTTGACTAGAACCATAACACTCACCAGCCCGGCTTTGGGCACGACCCTCCAGATATTCTACGTGGTCTCGGCAATGTTCTGGTGTTTAAATATGCTTAAGCTGTTAGAAATTAAGAAGACGAGAAAAGTGGATTAA

Protein

MAEFSFANASVENGFSDFVTDHLKGVGRLFYINSPQDSMFEKKDDVPNFFKQSWPYFFIFMILEHIVLRLEGKPGVRLNDGITSISHGIFQECGRIIWRGAESYLYTWIYTNYRLVELPWDSTLTWYAAALGVDFCYYWMHRACHEVHILWAQHQVHHTSEDFNMGVGIRQSVLQGWCGFIFYLPLAFAIPPAQFVVHHQFSYLYMFWIHTEAIKSLGPLEYILNTPSHHRVHHGSNKYCLDVNYGGVLIVWDRLFGTFKPETDKIEIVYGLIYNQPSFNPLYLQSFYNGYVLEKFRSYESWGDKMRAIFWGPSWEPGSPRLGDEDMKVDVENREKYDVHLPAWCNAYLVTHYAVVLYGFFELASRHMGMTPISVLIFVVYIIASLSVIGMLFDNSRHAPILEVLRCSALAFLTRTITLTSPALGTTLQIFYVVSAMFWCLNMLKLLEIKKTRKVD

Description

Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity).

Catalytic Activity

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O

Cofactor

Fe cation

Similarity

Belongs to the sterol desaturase family.
Belongs to the sterol desaturase family. TMEM195 subfamily.

Keywords

Complete proteome   Endoplasmic reticulum   Iron   Membrane   Oxidoreductase   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Alkylglycerol monooxygenase

Uniprot

H9IZ39   A0A2H1VBW9   A0A194QKM7   S4PI40   A0A212FCY1   A0A0N1PI25   + More
A0A0L7LDK7   A0A2A4J8U4   D7EI97   A0A1B6EA86   A0A0T6B3D7   U4USS1   T1HTZ1   A0A023FAT7   A0A1B6GR37   A0A0V0G4U7   A0A1B6M3R7   A0A1B6KJJ6   A0A1B6HPR2   A0A1Y1L3X3   A0A2J7RTH3   A0A146LEV2   A0A2R7W0F9   K7J2I3   A0A0C9Q044   A0A154P6N2   A0A2Z4BXV3   A0A226E2U3   A0A0L7QJV5   J9JK38   A0A0N0U5E3   A0A0N8BMF9   A0A087ZYM1   A0A3L8DHM5   A0A0C9QTY4   A0A0P6HWH9   A0A0P6EGG1   A0A0N7ZY87   A0A0P5TMW8   A0A3B3SLW9   A0A1S3K486   A0A026WR39   A0A1D2MM50   A0A2S2NH43   A0A1S3K599   A0A3Q4MTU5   A0A087T274   A0A0P5KF54   A0A3B5AFM2   A0A3B4T4H0   A0A3B4XT93   A0A0P5QZF8   A0A0S7FS93   A0A3B5PSG2   A0A0P5PAD0   A0A3B4G731   A0A1S3NZ56   A0A3Q3C1A4   A0A3Q1HAC9   A0A3Q3QD12   A0A3B3X6I4   A0A087Y382   A0A3P8NTS2   A0A3P9CDG8   A0A3Q3FFL8   A0A2I4C3B9   A0A0P5ACZ0   A0A3P8RMI6   A0A3Q2P712   A0A3P9I814   A0A3Q3BD65   A0A3Q0RSV3   A0A3P9KPC3   A0A2U9CGG6   A0A146VL80   A0A146MT81   A0A1A8MNT9   A0A1A8P5N1   A0A1A8D166   A0A3Q1C954   A0A1A7XCK1   I3N747   A0A1A8J5F7   H2MQ76   A0A158NP09   A0A3B5LNN6   A0A1A8EY34   A0A3Q1HAS7   A0A1A8UHL5   A0A3B3BBS0   Q5M8F9   E9GN23   A0A0P5RC89   A0A164RKX8   A0A3Q3M3Z6   A0A1W4Z6U2   A0A3B5QXY4   A0A060WCE3   A0A218V8M9  

EC Number

1.14.16.5

Pubmed

19121390    26354079    23622113    22118469    26227816    18362917    + More
19820115    23537049    25474469    28004739    26823975    20075255    30249741    29240929    24508170    27289101    25186727    23542700    17554307    21347285    29451363    21292972    24755649   

EMBL

BABH01011062    BABH01011063    BABH01011064    ODYU01001708    SOQ38286.1    KQ458714    + More
KPJ05470.1    GAIX01001986    JAA90574.1    AGBW02009122    OWR51605.1    KQ461002    KPJ10047.1    JTDY01001574    KOB73485.1    NWSH01002571    PCG67954.1    DS497675    EFA11751.1    GEDC01015428    GEDC01002534    JAS21870.1    JAS34764.1    LJIG01016051    KRT81761.1    KB632350    ERL93226.1    ACPB03000518    GBBI01000262    JAC18450.1    GECZ01029469    GECZ01025493    GECZ01018520    GECZ01017475    GECZ01015809    GECZ01013477    GECZ01009493    GECZ01004890    GECZ01004123    JAS40300.1    JAS44276.1    JAS51249.1    JAS52294.1    JAS53960.1    JAS56292.1    JAS60276.1    JAS64879.1    JAS65646.1    GECL01003048    JAP03076.1    GEBQ01009424    JAT30553.1    GEBQ01028354    JAT11623.1    GECU01034121    GECU01031029    GECU01011312    JAS73585.1    JAS76677.1    JAS96394.1    GEZM01065669    GEZM01065661    JAV68382.1    NEVH01000003    PNF44133.1    GDHC01011836    JAQ06793.1    KK854121    PTY11655.1    GBYB01007205    GBYB01007208    JAG76972.1    JAG76975.1    KQ434813    KZC06790.1    MF465856    AWU67707.1    LNIX01000007    OXA52052.1    KQ415041    KOC58869.1    ABLF02033072    KQ435775    KOX74952.1    GDIQ01163387    JAK88338.1    QOIP01000008    RLU19663.1    GBYB01007204    JAG76971.1    GDIQ01013255    JAN81482.1    GDIQ01064014    JAN30723.1    GDIP01200841    JAJ22561.1    GDIP01127549    JAL76165.1    KK107126    EZA58443.1    LJIJ01000870    ODM94028.1    GGMR01003613    MBY16232.1    KK113054    KFM59213.1    GDIQ01185061    JAK66664.1    GDIQ01110095    JAL41631.1    GBYX01461668    GBYX01461667    GBYX01461666    GBYX01461664    GBYX01461663    GBYX01461662    GBYX01461661    JAO19908.1    GDIQ01131396    JAL20330.1    AYCK01013203    AYCK01013204    AYCK01013205    AYCK01013206    AYCK01013207    GDIP01200840    JAJ22562.1    CP026258    AWP15689.1    AWP15690.1    AWP15691.1    GCES01068110    JAR18213.1    GCES01163908    GCES01163907    JAQ22415.1    HAEF01017344    SBR58503.1    HAEH01005388    SBR76389.1    HADZ01020660    SBP84601.1    HADW01014154    SBP15554.1    AGTP01054177    AGTP01054178    AGTP01054179    AGTP01054180    AGTP01054181    AGTP01054182    AGTP01054183    AGTP01054184    AGTP01054185    AGTP01054186    HAED01017483    SBR03928.1    ADTU01022007    ADTU01022008    HAEB01004921    SBQ51448.1    HAEJ01007118    SBS47575.1    BC088041    GL732554    EFX78959.1    GDIQ01111889    JAL39837.1    LRGB01002190    KZS08741.1    FR904483    CDQ64802.1    MUZQ01000031    OWK62051.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000037510    UP000218220    + More
UP000007266    UP000030742    UP000015103    UP000235965    UP000002358    UP000076502    UP000198287    UP000053825    UP000007819    UP000053105    UP000005203    UP000279307    UP000261540    UP000085678    UP000053097    UP000094527    UP000261580    UP000054359    UP000261400    UP000261420    UP000261360    UP000002852    UP000261460    UP000087266    UP000264840    UP000257200    UP000261600    UP000261480    UP000028760    UP000265100    UP000265160    UP000261660    UP000192220    UP000265080    UP000265000    UP000265200    UP000264800    UP000261340    UP000265180    UP000246464    UP000257160    UP000005215    UP000001038    UP000005205    UP000261380    UP000265040    UP000261560    UP000008143    UP000000305    UP000076858    UP000261640    UP000192224    UP000193380    UP000197619   

PRIDE

H9IZ39    Q5M8F9   

Pfam

PF04116   FA_hydroxylase

Interpro

IPR006694   Fatty_acid_hydroxylase       

ProteinModelPortal

H9IZ39   A0A2H1VBW9   A0A194QKM7   S4PI40   A0A212FCY1   A0A0N1PI25   + More
A0A0L7LDK7   A0A2A4J8U4   D7EI97   A0A1B6EA86   A0A0T6B3D7   U4USS1   T1HTZ1   A0A023FAT7   A0A1B6GR37   A0A0V0G4U7   A0A1B6M3R7   A0A1B6KJJ6   A0A1B6HPR2   A0A1Y1L3X3   A0A2J7RTH3   A0A146LEV2   A0A2R7W0F9   K7J2I3   A0A0C9Q044   A0A154P6N2   A0A2Z4BXV3   A0A226E2U3   A0A0L7QJV5   J9JK38   A0A0N0U5E3   A0A0N8BMF9   A0A087ZYM1   A0A3L8DHM5   A0A0C9QTY4   A0A0P6HWH9   A0A0P6EGG1   A0A0N7ZY87   A0A0P5TMW8   A0A3B3SLW9   A0A1S3K486   A0A026WR39   A0A1D2MM50   A0A2S2NH43   A0A1S3K599   A0A3Q4MTU5   A0A087T274   A0A0P5KF54   A0A3B5AFM2   A0A3B4T4H0   A0A3B4XT93   A0A0P5QZF8   A0A0S7FS93   A0A3B5PSG2   A0A0P5PAD0   A0A3B4G731   A0A1S3NZ56   A0A3Q3C1A4   A0A3Q1HAC9   A0A3Q3QD12   A0A3B3X6I4   A0A087Y382   A0A3P8NTS2   A0A3P9CDG8   A0A3Q3FFL8   A0A2I4C3B9   A0A0P5ACZ0   A0A3P8RMI6   A0A3Q2P712   A0A3P9I814   A0A3Q3BD65   A0A3Q0RSV3   A0A3P9KPC3   A0A2U9CGG6   A0A146VL80   A0A146MT81   A0A1A8MNT9   A0A1A8P5N1   A0A1A8D166   A0A3Q1C954   A0A1A7XCK1   I3N747   A0A1A8J5F7   H2MQ76   A0A158NP09   A0A3B5LNN6   A0A1A8EY34   A0A3Q1HAS7   A0A1A8UHL5   A0A3B3BBS0   Q5M8F9   E9GN23   A0A0P5RC89   A0A164RKX8   A0A3Q3M3Z6   A0A1W4Z6U2   A0A3B5QXY4   A0A060WCE3   A0A218V8M9  

KEGG

101737166    K15537 alkylglycerol monooxygenase [EC:1.14.16.5] | (RefSeq) alkylglycerol monooxygenase-like

GO

GO:0016021   GO:0005506   GO:0016491   GO:0008610   GO:0004497   GO:0005783   GO:0006643   GO:0050479   GO:0046485   GO:0005789   GO:0006633   GO:0005515   GO:0008237   GO:0008270   GO:0006511   GO:0005525   GO:0003824   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  

Length:

456

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

95.52921

Exp number, first 60 AAs:

3.39837

Total prob of N-in:

0.39289

outside

1  -  338

TMhelix

339  -  361

inside

362  -  373

TMhelix

374  -  393

outside

394  -  421

TMhelix

422  -  444

inside

445  -  456

 

 

Pi

204.534893

Theta

204.738155

Tajima's D

-1.043182

CLR

172.300839

CSRT

0.129643517824109

Interpretation

Uncertain