Silkworm Genome Informatics Database

Gene

KWMTBOMO05262 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002415

Annotation

PREDICTED:_DNA_polymerase_zeta_catalytic_subunit_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr9(-):12208052-12221834 View in EpiBrowser

Full name

DNA polymerase

Location in the cell

Nuclear Reliability : 3.718

CDS

ATGAGTTCATTGCAGTTAAGTCACCATAATCCGGAGTTTTCAGTGCGCATTGTCGTATGTGATCATTATATGACGAAACCAACTGCAGGTCTGGATGTTACTTATTCAGAATTCAGAGGAACTGACATCAAACAGGTACCAGTTCTCAGAATATTTGGACCAGCAAAAGATGGGTACAAGGCCTGTTTACATATTCATGGGGTATTTCCCTATTTCTACATACCATGTCCAACTCAAAATCCAGAGCCGCAACTTTTGTATCAGATAGCAGCAAGTTTGGATAAAGCTTTAAATATAGCCATGAAACAGGCAACATCTTCCAATCAACATGTTTACAAAATATCACTAGTCAAAGGCTTACCTTTTTACGGATACCATGATAAAGAGCATTTATATCTGAAAGTTTTTCTGTACAGCCCTGGGTTAATAAAGCAAGCAGTTGAACTCTTCAGTTCTGGGGCTATTTTAGGCCAGACATTTCAACCTCACGAATCACATCTAAACTTCACATTACAATTCTTTATAGATTTCAATCTTTTCGGAATGAGCGACATTGATTTGCAAAGCGTACAATTCCGAAAATCTGGGTTTTCTCAAAAGAGCAATGAAGTGTTATTTGATACAAAAGAAAATACTTTAACCTCGGAAAGCAGTTGCCATTACGAAGCTGACTGTATGGCTTCTCATATTATTAACCGTCAACGAATAGGTAAAGGAGATGGTATAGAAAATCCAGGATTAGAAGAAGTTTGGAACCAAGAGTTGGAAAGGCGGAAACAGTTAAATATGTCTTTAGCCTCAAAGTCACTCTCTCAAGGTCTTACTTCTTTAAAACAAGTAGAGACAGATTCACACTACAAATTCGAAAATATATTTGCCGTAAAATTATCAAATAAAATTGATAAGCCTGTTCTTCTAGAGCACGCTTATTATCCAGCTGAGACTCTAGGAGATACGCAGCTGTTTAAAGCAGTTGATGTATCAATACATCTGCCTAGTAAAGACTTAGATTTGACCTTAAATAGAACGACAAAAATGAATTTAAATGAACACGAGGAAGAAGATTTGGATACCACCATTGTTGATGAAAATTTAGTCCTAAACAGTTCCATGTCTTTACAATACAGTCAAGTTTTGTTAAACAGTGAAGATATGGAATTAATTGATATGTTGCATGATATGGACCAACAACGTGTTGAGGAAGACAGCATCATGGGGACTCCAGCAAACCGAGATCAAGAAGTTGATATGGAATTAGATGATGCAGAATACTCTAGGATATTTAATGATGATTCTGTTTGTCATGATCAAAATGAAAGTGAAAATAATGGCAGTCCTTTGTCTTGGCACGACTCTTTTTGGGATGGAGCTAATATTCCACAATTAGACGGCACATTCGACAACGACCATGTCACAAAAGTTCGGAAAAAAAGAAGACGAACTCTTCAATTAGGGTTATCTAGGCCAAAGAAAAAAAACGAAAGGGTAAATAATCCAACAAATACAGATTCTAATATAGACACTAGTGAAATAGACGAGATAAATGTTTCCAGAGAAACTGCTGATGGTGATGTATGTATCTCAGAACTAGTAAGGGCTAGCAAAATTTCAAAAACGTCAATAGAAAACACTGAAATTAAATCAGAAGAAACATTCATAGATGCAGTGTCTAGAATAACGGCTAAGCAAAATATTGTCAAGCTGATGAATAAATCTGAAATTTACGATTTACAAAACAAATTCGTACCAACAGCAGGTCCCTCTAATAAACCCGTTGATTGTGACAACACGGAAATGGGTAATTCATCAAATAACGAATTAGAATTATCACCTGATGGTAATGAACTAGGTATAGTTAGCTTTTATGATGCATCTAAAGTGTTTGATGATTCTTTTAATCAAACATTTTTACAAGAACAGACAAATTGTGATGACTGTTCTGATATTATTGCAAATGAATATGAAAAACAAGAAGACTATGACAAATTTAAAGATACGGAACTAAAATTAGATGTATCAGTAAACGAAAAACTAGACACTGGCATTAAAATTTTTACTCCAACCGTAAAGCCACCAACTAAAAATGAAATGGAAACTAAATATAAAATCCCAAAAACAAAACAGGTTCAACCATTTTTTTCTGATTATAAAGATGTTGGAGATAAAGTAGAAATCGGCCAATTGGTTTTAAAATTGCACAGTAATTTGTCACGCGACCAAAAACCGTTTGAAAAAGTATTGGAAACTGAAAGCATTGAAAATTGGAGACAACTATTATTTCTACAAAAGTATGCAACACAAGACGACTACAAACCAGACACGCTGAGAACATTGTTAGCAGGAAATTCAAGATATGTTATACAGCCTGTTGTGAGACCTCCAACGAGTGAGCAAGTAAAGAAATGGATAAATGAACAAAAAGCTCTCCAACTATTGTCACAATTTAGCTCAGAACAAGCAATTTCCAAAAACATGGATGATTTCAATAATTCTCAAGCTTTAGGTTTAAATGAAGATGAAATTAATAGTAGTATCGTAAGCATCGAAAATTGCGAAAGTGGAAAACCGGATAACAGTTTTCAAATAACATTAAATACTGACGGATCTTTCCTTTGCTTTGGAAATACTGATATCTGTAAAGATAATAATTCCTGCGAAGTAGCCACAGTGAACGCGGACTTTCTCACTTCAATGGTTATTGAAGTCCACACTTCTGTGAGAGGTGATATGCATCCAGATCCGGCGGTAGATCCAATAAAAGCTGTGTTTTACTCTGTTATCAATGACTGCCCGAATAATCATTTCCTAAAAAAATCTTTAACGGGAATCATTGTGGTCGATTCAAGTTCCCGAAAATATTTAGATGGGTGCGTATTCAATGTTCCTGTAATCTATGTCAGTAATGAAATTGAAACCATCGATGAAGTAATTAAATTAGTAAACATACATGATCCAGACATAATGTGCGGTTATGAAATAGAAATGAATTCTTGGGGATACGTGTTGGAAAGAGCCGAGATTCTTGGGTTGGATGTTTTAAAAGATTTATCTAGAATTACCGAGAAGAACAGACAAAAACGATGGATGAAAAATGAATCCGATTACGAAGGTAGAATTATTGGGAGAGTTATATTCAATGTGTGGCGTTTGTTTCGTCACGAACTGGCATTATCAAGCTACAGTTTCGAGAATTGTATGTACGAAGTATTGAATGAACGAGTACCGTCATACAGCTATGCGCAATTGTCGGATTGGTGGTGCGACGAATCGAAAATGCTAAGATGGATTCCCGTCGAGTATTATTTGACCAAACTATCGGGTACAGTCAGAATGCTACAGAAATTGGATATCATAAATAGAACGTCGGAATTGGCCAGATTATTTGGTCTGCAGTGGTGGGAAGTTTTGTCCAGAGGATCACAGTTCCGTGTCGAATCTCTGATGCTACGAGCGGCCAGACCTCTCAATCTTATTGCTCTATCCCCAACTATAAAACAGAGATCTACCATGCGAGCCCCTGAAACTTTGCCTCTTATATTTGAACCGGAATCTCGATTCTACTCGGATCCAGTGATTGTCCTAGATTTTCAGAGTCTGTATCCTTCGATGATGATTGCCTACAACTATTGCTTCTCAACGTGTATCGGTCGCGTGCAGAATATTAATGGCGAAACGGCCTATGAGTTCGGGGCATGGCGCTTAAGGATTCCTAGATCAAAATTAGAAGCTCTTGTTAAAAACTCCCTAATACATTGGTCGCCGGTTGGGATTGGATTTGTTAAAACGTCAGTTCGGAGAGGCGTACTGCCAGCGCTCTTGAGGAGAATACTTGCTGCTAGACAAGCAGTTAAGAAAAGTATGAAAATGCAGAATGATGAGGCAGTAAAGAAAGCGATGCATTCCAGACAATTAGGTTTAAAATTAATAGCTAACGTGACATACGGATATACAGCTGCGAACTTCAGTGGACGTATGCCTTGCGTGGAAGTCGCCGATAGTGTCGTGGCTAAAGGCAGAGAAACGCTTGAAAGAGCCATAAAATTAGTTCGGGAAAATACTACTTGGAATGCCAAGGTTATATACGGTGACACTGATTCAATGTTCGTGTTGGTGCCCGGCAGGAGTCGTTTAGAAGCATTCGAAATCGGTCAGCAGATAGCCGATGCTGTGACTGCAGATAACCCTCCACCAGTTGCACTTAAATTAGAAAAGGTATATCAACCGTGCATTCTGCAAACGAAAAAACGCTACGTTGGCTTTATGTTCGAGAGTCCCGATCAAGAGAAACCCACGTATGAAGCAAAAGGAATAGAAACAGTCCGAAGAGACGGCTGTCCCGCTGGAGTAAAGCTTCTACGTCAATCCTTGTGTGAATTATTTACCCATGGCGATATGTCGGTGGTGAAACGTCTAGTGAAGGCCACGCTGTCCCGTCTGGCGGAGACCTCGCTCCCGGTACACGAACTCTTCTTTACGCGCGAGTACCACGGACAGGCTGGGTACAGGCCTGGGGCTTCTGCGCCGCCAAACGAAATTGCGAAACGTATAGGTATGAAAGACCGTCGTGCGATACCAAGAACAGGCTGGCGGGTATCCTGGCTAGTTACGTGCGGAGCGCCCGGCGTGCCGCTGGTGCGCTTGGCTCGTACTCCGCAGGAGCTGACCCGCGATCGCTCGTTACGACCTCATGTGGCGTACTACGCAACTCGCGTACTCTTGCCGCCCCTGCATCGCTGTCTATCACTCTTGGGCGTTGATGTATTTAAATGGTGGAACGAGCTTGGCTACAATCGCACAGCCCAGCAACGAGAGCAGACACAGTCCGGTGGCATCGAGAAGTACATGTCCCGCGAGCGGTGCGCGGTGTGCGGCGTGCGCACCATCGTCCGCAGCGCCGTGTGCCCGCAGTGTGCGCACACGCAGCGCGCCTGCGTCGTGCTACAGACACGTGCGAACAACGCTGCCACCTACTTAGACTCCTGTTACTCGATATGTAGTTCCTGTTGTGGCCACACCGACACTGAGAAATGTCAAAATGTGGAATGTCCAGTTCTTTGGCGACGTTCAAGCGCATGTGAAAGATATTCTCAAATGACGGAATTGCTAACTCATTTACCATGA

Protein

MSSLQLSHHNPEFSVRIVVCDHYMTKPTAGLDVTYSEFRGTDIKQVPVLRIFGPAKDGYKACLHIHGVFPYFYIPCPTQNPEPQLLYQIAASLDKALNIAMKQATSSNQHVYKISLVKGLPFYGYHDKEHLYLKVFLYSPGLIKQAVELFSSGAILGQTFQPHESHLNFTLQFFIDFNLFGMSDIDLQSVQFRKSGFSQKSNEVLFDTKENTLTSESSCHYEADCMASHIINRQRIGKGDGIENPGLEEVWNQELERRKQLNMSLASKSLSQGLTSLKQVETDSHYKFENIFAVKLSNKIDKPVLLEHAYYPAETLGDTQLFKAVDVSIHLPSKDLDLTLNRTTKMNLNEHEEEDLDTTIVDENLVLNSSMSLQYSQVLLNSEDMELIDMLHDMDQQRVEEDSIMGTPANRDQEVDMELDDAEYSRIFNDDSVCHDQNESENNGSPLSWHDSFWDGANIPQLDGTFDNDHVTKVRKKRRRTLQLGLSRPKKKNERVNNPTNTDSNIDTSEIDEINVSRETADGDVCISELVRASKISKTSIENTEIKSEETFIDAVSRITAKQNIVKLMNKSEIYDLQNKFVPTAGPSNKPVDCDNTEMGNSSNNELELSPDGNELGIVSFYDASKVFDDSFNQTFLQEQTNCDDCSDIIANEYEKQEDYDKFKDTELKLDVSVNEKLDTGIKIFTPTVKPPTKNEMETKYKIPKTKQVQPFFSDYKDVGDKVEIGQLVLKLHSNLSRDQKPFEKVLETESIENWRQLLFLQKYATQDDYKPDTLRTLLAGNSRYVIQPVVRPPTSEQVKKWINEQKALQLLSQFSSEQAISKNMDDFNNSQALGLNEDEINSSIVSIENCESGKPDNSFQITLNTDGSFLCFGNTDICKDNNSCEVATVNADFLTSMVIEVHTSVRGDMHPDPAVDPIKAVFYSVINDCPNNHFLKKSLTGIIVVDSSSRKYLDGCVFNVPVIYVSNEIETIDEVIKLVNIHDPDIMCGYEIEMNSWGYVLERAEILGLDVLKDLSRITEKNRQKRWMKNESDYEGRIIGRVIFNVWRLFRHELALSSYSFENCMYEVLNERVPSYSYAQLSDWWCDESKMLRWIPVEYYLTKLSGTVRMLQKLDIINRTSELARLFGLQWWEVLSRGSQFRVESLMLRAARPLNLIALSPTIKQRSTMRAPETLPLIFEPESRFYSDPVIVLDFQSLYPSMMIAYNYCFSTCIGRVQNINGETAYEFGAWRLRIPRSKLEALVKNSLIHWSPVGIGFVKTSVRRGVLPALLRRILAARQAVKKSMKMQNDEAVKKAMHSRQLGLKLIANVTYGYTAANFSGRMPCVEVADSVVAKGRETLERAIKLVRENTTWNAKVIYGDTDSMFVLVPGRSRLEAFEIGQQIADAVTADNPPPVALKLEKVYQPCILQTKKRYVGFMFESPDQEKPTYEAKGIETVRRDGCPAGVKLLRQSLCELFTHGDMSVVKRLVKATLSRLAETSLPVHELFFTREYHGQAGYRPGASAPPNEIAKRIGMKDRRAIPRTGWRVSWLVTCGAPGVPLVRLARTPQELTRDRSLRPHVAYYATRVLLPPLHRCLSLLGVDVFKWWNELGYNRTAQQREQTQSGGIEKYMSRERCAVCGVRTIVRSAVCPQCAHTQRACVVLQTRANNAATYLDSCYSICSSCCGHTDTEKCQNVECPVLWRRSSACERYSQMTELLTHLP

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

[4Fe-4S] cluster

Similarity

Belongs to the DNA polymerase type-B family.

Uniprot

H9IYT0 A0A2H1WJ56 A0A194QBH8 A0A3S2LU52 A0A194RND0 A0A212F1E2 + More
A0A0L7LF25 A0A195BWS2 A0A195ELU5 Q16UP4 A0A2A3E9R8

EC Number

2.7.7.7

Pubmed

19121390 26354079 22118469 26227816 17510324

EMBL

BABH01010867 ODYU01009018 SOQ53110.1 KQ459220 KPJ02898.1 RSAL01000222 + More
RVE44019.1 KQ459984 KPJ19017.1 AGBW02010898 OWR47560.1 JTDY01001387 KOB74005.1 KQ976396 KYM93032.1 KQ978691 KYN29250.1 CH477617 EAT38236.1 KZ288325 PBC28032.1

Proteomes

UP000005204 UP000053268 UP000283053 UP000053240 UP000007151 UP000037510 + More
UP000078540 UP000078492 UP000008820 UP000242457

PRIDE

H9IYT0

Pfam

PF00136   DNA_pol_B        + More
PF03104   DNA_pol_B_exo1
PF14260   zf-C4pol
PF00631   G-gamma

Interpro

IPR030559   PolZ_Rev3        + More
IPR012337   RNaseH-like_sf
IPR023211   DNA_pol_palm_dom_sf
IPR042087   DNA_pol_B_C
IPR017964   DNA-dir_DNA_pol_B_CS
IPR036397   RNaseH_sf
IPR006172   DNA-dir_DNA_pol_B
IPR006134   DNA-dir_DNA_pol_B_multi_dom
IPR006133   DNA-dir_DNA_pol_B_exonuc
IPR025687   Znf-C4pol
IPR013083   Znf_RING/FYVE/PHD
IPR001965   Znf_PHD
IPR036284   GGL_sf
IPR011011   Znf_FYVE_PHD
IPR015898   G-protein_gamma-like_dom
IPR042013   PHF7/G2E3_ePHD
IPR034732   EPHD
IPR042012   PHF7/G2E3_PHD
IPR019786   Zinc_finger_PHD-type_CS

SUPFAM

SSF53098   SSF53098        + More
SSF57903   SSF57903
SSF48670   SSF48670

Gene 3D

1.10.132.60 3.30.420.10 3.90.1600.10 3.30.40.10 4.10.260.10

CDD

cd00068  GGL
cd15496  PHD_PHF7_G2E3_like
cd15669  ePHD_PHF7_G2E3_like

ProteinModelPortal

H9IYT0 A0A2H1WJ56 A0A194QBH8 A0A3S2LU52 A0A194RND0 A0A212F1E2 + More
A0A0L7LF25 A0A195BWS2 A0A195ELU5 Q16UP4 A0A2A3E9R8

PDB

3IAY E-value=9.39113e-49, Score=494

KEGG

101746813 K02350 DNA polymerase zeta [EC:2.7.7.7] | (RefSeq) DNA polymerase zeta catalytic subunit

PATHWAY

03460 Fanconi anemia pathway - Bombyx mori (domestic silkworm)

GO

GO:0000166 GO:0003887 GO:0006260 GO:0003677 GO:0016035 GO:0019985 GO:0051539 GO:0005634 GO:0046872 GO:0007186 GO:0003676 GO:0008408 GO:0005524 GO:0001664 GO:0005525 GO:0016491 GO:0003824

PANTHER

PTHR45812

Subcellular location

Nucleus

Length:

1706

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.08047

Exp number, first 60 AAs:

0.00064

Total prob of N-in:

0.00034

outside

1 - 1706

Pi

213.412532

Theta

164.713746

Tajima's D

0.189818

CLR

1.493771

CSRT

0.420328983550822

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics