Gene

KWMTBOMO05222

Pre Gene Modal

BGIBMGA002474

Annotation

A_disintegrin_and_metalloproteinase_with_thrombospondin_motifs_1_precursor_[Bombyx_mori]

Location

Bomo_Chr9(+):11366924-11391848      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.232 Mitochondrial   Reliability : 1.398

CDS

ATGCGTGAGCGCAGCGCGCCGCACCGCGACCCACAGAGAGGCGCAGCTCGCGGCGACGCACGGACCATGCCGTGCTGCCTCTGGGCCGCGCTGTCTCTGCTCCTCGCGGTCGTCGGCGCCGGCGCCTGGACACCGCCGAGACAGCCCTTGCTGCTCACTCCGAGACATCGCAGACACGCGCAAGAAACTCATCACTTGCGACTCCTCGGTTGGGATCTCAAGTTAAAAGAAAACAAAGCTATTCGTTCGCCTTATTATAAGGAATGTCAGTTTTTTACGGGACGCGTTCTTCATGAAGAGGGCTCCGCTGTGACGGTTACCGAATGTGACGGACAGCTGTACGGGCTGCTGCAGGTCGGCGGTGAAGAGTTCGTGCTGCAGCCGACCAGAACGCAGGAGAAACACGTGTTACGACGCCGAGACGTTACGCACAGCGAGCGTTCGGCCGAGTACAACCTCACCGGTGATACGGTCATCGACCTTGATCTTGACTTCGATGAAGATGATGACCTGTTACCGACCTCGCACGTACATCCGCGGCACAGCGATCATTCCGACAAAGAGTACTTCCATGACATGCATTTGTTCAGAAGACCTGCGTCAGGTGTAAAGGGTCTTTGGCTTGAACTGGCCATCGTTGCCGACAACACCATGTTGAAATTTCATGGCCGAGAACGTGTCAAACATTATATTTTAGCTTTAATGAATATTGTCAGTGCCATCTTCAATGACCCATCACTGGGCTCTAACATCACGTTAGTGATCAACAAATTGTTTCTCTACGAGGACAAGGACATAATTTTGAAGTACGGCAACATCAAAAAATCGTTAGAAGCTATTAACAAGTGGAACTATAGACATCTCATGAAGCTACCTGAAGGTAGCACAGGATGGGACGCCACAATATGGTTGACGAGATCCCAGCTTGGAGGGCCTTCCGGGTTCGCCCCCGTAGGTGGGGTCTGCACCAAAACGCGGTCAGCCGCCATCGACCGCGACGAAGGATTGACCAGTGCTTTTGTAATTGCACACGAACTCGCTCACTTATTAGGGTTGACCCACGATGGAGAAGGCAATTGTCAGTCTGAAGCGCTTCGAGGCTCTGTAATGGCACCGACAGTATTGGCTACCCTACACAACTTTGCCTGGTCAAGTTGTTCAAAGGAACAATTTCATGCGAAATCAAAGAAGTGGTGGTGCCTCCATGAGCGTAGCACTGACGAGGGTGTGGAACTAGGTGGTGCTAAGGAGCTCTCAAATTATGTCTTCACAATGGATGAACAGTGCAGGACTGAATTCGGAGAAGGGTAA

Protein

MRERSAPHRDPQRGAARGDARTMPCCLWAALSLLLAVVGAGAWTPPRQPLLLTPRHRRHAQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIDLDLDFDEDDDLLPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEGNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERSTDEGVELGGAKELSNYVFTMDEQCRTEFGEG

Uniprot

Q5W7F4   H9IYY9   A0A3S2L1Y7   A0A194QHE7   A0A194RNT2   A0A2H1WA39   + More
A0A232ESI1   A0A1W4WEI8   A0A1W4WEV2   A0A1W4WDK2   A0A088A8D9   A0A1Y1NAP5   A0A1Y1NDK9   A0A1Y1NAP7   A0A087ZT59   N6UKX4   A0A0M9A160   A0A139WN17   A0A139WNG8   A0A0C9RBA9   A0A2A3E8G8   A0A154PKF8   A0A0L7QZN0   T1IWV1   A0A0S7K1N5   A0A0Q3P5Y5   A0A1S3F9I3   A0A0S7K4W3   A0A151P062   A0A0S7K1K9   A0A3B4YNV9   A0A3P9N5L5   A0A3P9N0U9   A0A0S7K268   B2RXX5   A0A3B3C245   A0A3B5Q096   A0A3Q3IDJ4   A0A3Q0FV96   A0A1A7ZQ54   I3KGQ6   A0A3M0KF78   A0A3B4V8Y9   A0A3B4CC54   A0A3P8WFS5   M3ZWG6   A0A091P525   B2RXR8   A0A1A8IBL9   A0A3Q0T3H7   A0A3P8NSK8   A0A3B4YSZ2   A0A3Q0G275   A0A3P8TWY8   A0A091V4H7   A0A3Q1AYX9   A0A3B3V2H4   A0A096LXZ6   A0A091EU20   A0A094MUV0   A0A1W5AT79   A0A3S2P7Z4   A0A087XK85   W5UIH9   H2U8I4   A0A096MCV0   A0A3Q3MME4   A0A3B5LAW6   M4AL57   A0A0F8B1S6  

Pubmed

15898116    19121390    26354079    28648823    28004739    23537049    + More
18362917    19820115    22293439    12040188    15489334    19468303    29451363    23542700    25186727    24487278    23127152    21551351    25835551   

EMBL

AB194270    BAD69559.2    BABH01010769    RSAL01000231    RVE43838.1    KQ459220    + More
KPJ02866.1    KQ459984    KPJ18985.1    ODYU01007276    SOQ49907.1    NNAY01002418    OXU21320.1    GEZM01007719    JAV94982.1    GEZM01007721    JAV94980.1    GEZM01007720    JAV94981.1    APGK01029202    KB740727    ENN79337.1    KQ435768    KOX75240.1    KQ971311    KYB29418.1    KYB29417.1    GBYB01005610    JAG75377.1    KZ288325    PBC28015.1    KQ434946    KZC12332.1    KQ414680    KOC64011.1    JH431630    GBYX01223105    JAO71408.1    LMAW01002878    KQK76163.1    GBYX01223110    JAO71403.1    AKHW03001467    KYO42424.1    GBYX01223117    GBYX01223109    JAO71404.1    GBYX01223116    JAO71397.1    AC123530    AC151895    BC158014    CH466553    AAI58015.1    EDL32150.1    HADY01005645    HAEJ01008758    SBP44130.1    AERX01007355    AERX01007356    QRBI01000108    RMC11848.1    KK668078    KFQ02695.1    BC157953    AAI57954.1    HAED01007483    SBQ93695.1    KL410604    KFQ97724.1    AYCK01006610    KK718970    KFO60491.1    KL350003    KFZ58286.1    CM012455    RVE59722.1    AYCK01007292    JT415790    AHH41821.1    KQ041942    KKF20668.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000053240    UP000215335    UP000192223    + More
UP000005203    UP000019118    UP000053105    UP000007266    UP000242457    UP000076502    UP000053825    UP000051836    UP000081671    UP000050525    UP000261360    UP000242638    UP000000589    UP000261560    UP000002852    UP000261600    UP000189705    UP000005207    UP000269221    UP000261420    UP000261440    UP000265120    UP000261340    UP000265100    UP000265080    UP000053283    UP000257160    UP000261500    UP000028760    UP000052976    UP000192224    UP000005226    UP000261640    UP000261380   

PRIDE

Q5W7F4    H9IYY9   

Pfam

PF00090   TSP_1        + More
PF01562   Pep_M12B_propep
PF01421   Reprolysin
PF17771   ADAM_CR_2
PF05986   ADAM_spacer1

Interpro

IPR001590   Peptidase_M12B        + More
IPR000884   TSP1_rpt       
IPR036383   TSP1_rpt_sf       
IPR041645   ADAM_CR_2       
IPR024079   MetalloPept_cat_dom_sf       
IPR002870   Peptidase_M12B_N       
IPR006586   ADAM_Cys-rich       
IPR013273   ADAMTS/ADAMTS-like       
IPR010909   PLAC       
IPR010294   ADAM_spacer1       

SUPFAM

SSF82895   SSF82895       

Gene 3D

2.20.100.10     3.40.390.10    

ProteinModelPortal

Q5W7F4   H9IYY9   A0A3S2L1Y7   A0A194QHE7   A0A194RNT2   A0A2H1WA39   + More
A0A232ESI1   A0A1W4WEI8   A0A1W4WEV2   A0A1W4WDK2   A0A088A8D9   A0A1Y1NAP5   A0A1Y1NDK9   A0A1Y1NAP7   A0A087ZT59   N6UKX4   A0A0M9A160   A0A139WN17   A0A139WNG8   A0A0C9RBA9   A0A2A3E8G8   A0A154PKF8   A0A0L7QZN0   T1IWV1   A0A0S7K1N5   A0A0Q3P5Y5   A0A1S3F9I3   A0A0S7K4W3   A0A151P062   A0A0S7K1K9   A0A3B4YNV9   A0A3P9N5L5   A0A3P9N0U9   A0A0S7K268   B2RXX5   A0A3B3C245   A0A3B5Q096   A0A3Q3IDJ4   A0A3Q0FV96   A0A1A7ZQ54   I3KGQ6   A0A3M0KF78   A0A3B4V8Y9   A0A3B4CC54   A0A3P8WFS5   M3ZWG6   A0A091P525   B2RXR8   A0A1A8IBL9   A0A3Q0T3H7   A0A3P8NSK8   A0A3B4YSZ2   A0A3Q0G275   A0A3P8TWY8   A0A091V4H7   A0A3Q1AYX9   A0A3B3V2H4   A0A096LXZ6   A0A091EU20   A0A094MUV0   A0A1W5AT79   A0A3S2P7Z4   A0A087XK85   W5UIH9   H2U8I4   A0A096MCV0   A0A3Q3MME4   A0A3B5LAW6   M4AL57   A0A0F8B1S6  

PDB

2V4B     E-value=4.35624e-21,     Score=250

KEGG

692529    K08619 a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-] | (RefSeq) Ada

GO

GO:0004222   GO:0007229   GO:0016021   GO:0008233   GO:0030199   GO:0005576   GO:0008237   GO:0006508   GO:0016020   GO:0006772   GO:0003677   GO:0001664   GO:0005525   GO:0016491   GO:0003824  

SignalP

Position:   1 - 42,         Likelihood:  0.519495

 

 

Length:

436

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.79601

Exp number, first 60 AAs:

20.7429

Total prob of N-in:

0.98991

POSSIBLE N-term signal

sequence

inside

1  -  24

TMhelix

25  -  44

outside

45  -  436

 

 

Pi

187.527411

Theta

170.213631

Tajima's D

0.209719

CLR

0.106331

CSRT

0.432328383580821

Interpretation

Uncertain