Gene

KWMTBOMO05213  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002432

Annotation

PREDICTED:_V-type_proton_ATPase_116_kDa_subunit_a_isoform_1_[Papilio_xuthus]

Location

Bomo_Chr9(-):11213718-11250633      View in EpiBrowser

Full name

V-type proton ATPase subunit a      

Location in the cell

PlasmaMembrane   Reliability : 4.581

CDS

ATGGGGGCTATGTTCCGGAGCGAGGAGATGGCTTTGTGCCAACTCTTCATTCAGCCCGAGGCGGCCTATACCTCCGTCTCAGAGCTTGGTGAAGCTGGCAGCGTGCAGTTCAGAGATTTAAATCCGGACGTAAATGCTTTCCAAAGGAAATTCGTTAACGAGGTGCGCCGTTGCGATGAAATGGAACGCAAACTCCGGTACATCGAGGCTGAGGTGCACAAAGATGGCGTCCACATTCCCGCCGTCAAGGAAGCCCCCCGAGCTCCAAACCCGAGGGAAATCATTGACTTGGAGGCACATTTAGAGAAAACCGAAAACGAAATTCTCGAGCTGTCACACAACGCGGTCAATTTGAAACAAAACTATCTGGAGTTGACCGAATTGAGACATGTCCTTGAAAAGACCGAAGCTTTCTTCACCGCACAGGAGGAAATCGGCATGGATTCTTTGACCAAGTCTTTAATATCTGACGAGACTGGTCAACAAGCGGCCACTCGCGGCCGCCTCGGGTTCGTTGCGGGCGTGGTCCAGCGCGAGCGCGTGCCCGCATTCGAACGGATGCTGTGGCGTATCTCGAGAGGCAACGTCTTCCTACGACGGGCTGAACTGGACAAGCCGCTCGAAGATCCTGCTACGGGTAACGAGATCTACAAGACCGTGTTCGTTGCGTTCTTCCAAGGCGAACAGCTAAAGTCCCGCATCAAGAAAGTGTGCACCGGTTTCCACGCCTCGCTGTACCCGTGCCCGCCTTCGAACACCGAACGACAGGACATGGTCAAGGGAGTCAGGACCAGACTCGAAGACCTTAACATGGTCTTGAACCAAACCCGCGACCACAGACAACGTGTGCTTGCAAGTGTTGCCAAGGAGCTGACCAGCTGGACCATAATGGTGAGGAAGATGAAGGCCATCTACCACACCCTAAATCTGTTCAACATGGATGTCACGAAGAAGTGCCTCATCGGTGAATGCTGGGTACCGACTGCTGATCTACCCAACGTACAAAAGGCACTGGCTGATGGTTCGAACGCATGCGGCAGTTCGATCCCGTCGTTCCTGAACTGCATCGAGACTGACGAGGAGCCGCCCACCTTCAACAGGACCAACAAGTTCACGCGCGGCTTCCAGAACCTCATCGATGCTTACGGAGTCGCCTCTTACCGCGAATGTAACCCGGCTTTGTACACGATCATAACGTTCCCGTTCTTGTTCGCTGTGATGTTCGGCGACCTTGGTCACGGCTGCATCATGGCGATGTTCGGCGGCTGGATGGTCGTGAAGGAAGTCTCGCTCGCCGCCAAGAAATCGAACAACGAAATCTGGAATATATTCTTCGCGGGCCGCTACATAATCCTGCTCATGGGCTGCTTCTCTATGTACACCGGCCTCGTGTACAACGATATCTTCTCCAAGTCTCTGAACATATTTGGCTCCTCTTGGCACATCCCGTACGACAACCACACGCTCGCTGAGAACGGCGCCTTGACGCTCGACCCTAAAGACGCCTACACCGAAGTGCCATACTTCATCGGTATCGACCCTATTTGGCAGAGCGCTGACAACAAGATTATCTTCCTCAACTCGTACAAAATGAAGCTGTCTATCATATTCGGTGTAATCCACATGATATTCGGTGTCTGCATGAGCGTGGTCAACTACAATTTCTTCAAGCGTCGCTACTCCATCTTCCTCGAGTTCCTCCCTCAGATCGTCTTTCTGGCGCTACTGTTCTTGTACATGGTGTTCATGATGTTCTTCAAATGGATCGCGTACAGCACTAAGAATGATGAGCTGGCGTACACCCAAGGCTGCGCTCCGTCGGTGCTGATCCTGTTCATCAACATGATGCTGTTCTCGAAGAACGTCCCGGAGGAGGGCTGCAAGGAGTTCATGTTCGACGCTCAGAGCGACATCCAGCGCGTGTTCGTGTTCATCGCGCTGCTCTGCATCCCCGTCATGCTGCTCGGGAAGCCGCTGTACCTGCTCGCCACTAAGAAGAACAACCCCAAGCCCGAACATTCCAACGGCAGCGTCAACCAAGGCATCGAGCTGCAGGAGCAGACCGACCTCGGCGACGTGCAGCCCAAGCCCGAAGCTAAGTCCAGCGGCGGGCACGACCACGAGGACGAGCCCTTCAGCGAGATCATGATCCACCAGGCCATCCACACCATCGAATACGTACTCAGCACCATCTCTCACACAGCCTCCTACCTCCGACTCTGGGCCTTGTCGCTCGCCCACGCTGAGTTGTCCGAAGTACTATGGAACATGGTGCTGACGTTCGGCTTGAAGGACCATAACTACGTGGGCGCCATCAAGCTGTACGTGGCGTTCTGTTTCTGGGCGCTGTTCACGCTCGCCATCCTCGTCATGATGGAGGGACTCTCCGCATTCTTGCATACTCTGCGTTTGCACTGGGTTGAATTCATGAGCAAATTCTACGCCGGTCTGGGCTACATCTTCCAGCCATTCTGTTTCAAGACGATCCTCGAACAAGAGGAAAATAAAGATGATTAA

Protein

MGAMFRSEEMALCQLFIQPEAAYTSVSELGEAGSVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRYIEAEVHKDGVHIPAVKEAPRAPNPREIIDLEAHLEKTENEILELSHNAVNLKQNYLELTELRHVLEKTEAFFTAQEEIGMDSLTKSLISDETGQQAATRGRLGFVAGVVQRERVPAFERMLWRISRGNVFLRRAELDKPLEDPATGNEIYKTVFVAFFQGEQLKSRIKKVCTGFHASLYPCPPSNTERQDMVKGVRTRLEDLNMVLNQTRDHRQRVLASVAKELTSWTIMVRKMKAIYHTLNLFNMDVTKKCLIGECWVPTADLPNVQKALADGSNACGSSIPSFLNCIETDEEPPTFNRTNKFTRGFQNLIDAYGVASYRECNPALYTIITFPFLFAVMFGDLGHGCIMAMFGGWMVVKEVSLAAKKSNNEIWNIFFAGRYIILLMGCFSMYTGLVYNDIFSKSLNIFGSSWHIPYDNHTLAENGALTLDPKDAYTEVPYFIGIDPIWQSADNKIIFLNSYKMKLSIIFGVIHMIFGVCMSVVNYNFFKRRYSIFLEFLPQIVFLALLFLYMVFMMFFKWIAYSTKNDELAYTQGCAPSVLILFINMMLFSKNVPEEGCKEFMFDAQSDIQRVFVFIALLCIPVMLLGKPLYLLATKKNNPKPEHSNGSVNQGIELQEQTDLGDVQPKPEAKSSGGHDHEDEPFSEIMIHQAIHTIEYVLSTISHTASYLRLWALSLAHAELSEVLWNMVLTFGLKDHNYVGAIKLYVAFCFWALFTLAILVMMEGLSAFLHTLRLHWVEFMSKFYAGLGYIFQPFCFKTILEQEENKDD

Description

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.

Similarity

Belongs to the V-ATPase 116 kDa subunit family.

Uniprot

H9IYU7   A0A194QD04   A0A1E1WPT2   A0A1B1UZP4   A0A194RMC5   A0A212ESI2   + More
S4PLD6   U5EY09   A0A1Q3FCP1   A0A1L8DEM8   A0A1L8DEX4   A0A023EW58   Q16HE2   A0A182USZ7   A0A182UDQ6   Q7PKS7   A0A182WSF2   A0A182L9N2   A0A182VZ95   A0A2C9GQN9   A0A182R647   A0A182M9P0   A0A182QWU8   A0A182PGR3   Q8T5K2   A0A182NS68   A0A182YAM6   A0A182IX69   A0A2M4A1G6   A0A2M4A171   A0A2M4BEH6   A0A182F7K3   A0A2M3YYH4   A0A2M3YYN2   W5JMD3   T1PG42   A0A1I8NRD1   A0A1J1HJB8   A0A1A9ZXN1   A0A1B6MKV2   A0A1B0BJB3   A0A1B6MPW5   A0A1A9VER2   A0A0K8TQR7   A0A336KNK4   A0A336M7G7   A0A1L8EDJ5   A0A1L8EDB7   B0W8G6   A0A1B0F9Q1   A0A087ZUG7   B4N9D9   A0A1W4U7R6   W8BF11   B4JF18   A0A0K8UV85   B4PLX2   Q9VE75   B3LW99   A0A034VLS7   B4I290   A0A0A1X2U8   B4G5D7   V9ILL6   Q299L9   K7J2E3   B4M3Z5   A0A2A3ELE4   A0A0L7QWI4   A0A0M5J4P9   A0A2J7RKU2   B4QUE6   A0A0C9R6G2   A0A3B0KN56   D6WCX7   A0A195CD36   A0A1B0D7J1   A0A0L0C6R8   A0A1Y1JVN1   A0A1Y1JSJ5   B4K928   A0A2H8TPX0   A0A067RRK3   A0A310S7A1   A0A195BIS9   E9JC15   E2BB77   A0A0K8V9Z6   A0A2H1WFR4   A0A195EZ62   A0A195DP30   U4U2F9   N6TTR3   A0A026VYX4   A0A0M9A6N9   N6TW70   J9JQN3   A0A0L0CSP3   A0A0P4VSQ7   A0A1B0B2T6  

Pubmed

19121390    26354079    22118469    23622113    24945155    26483478    + More
17510324    12364791    14747013    17210077    20966253    12060762    25244985    20920257    23761445    25315136    26369729    17994087    24495485    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    25348373    25830018    15632085    20075255    18362917    19820115    26108605    28004739    24845553    21282665    20798317    23537049    24508170    30249741    27129103   

EMBL

BABH01010757    BABH01010758    BABH01010759    KQ459220    KPJ02860.1    GDQN01008557    + More
GDQN01001991    JAT82497.1    JAT89063.1    KU550964    ANW09710.1    KQ459984    KPJ18978.1    AGBW02012778    OWR44452.1    GAIX01004080    JAA88480.1    GANO01000631    JAB59240.1    GFDL01009700    JAV25345.1    GFDF01009183    JAV04901.1    GFDF01009184    JAV04900.1    JXUM01123189    JXUM01123190    JXUM01123191    JXUM01123192    GAPW01000216    JAC13382.1    CH478180    EAT33671.1    AAAB01008987    EAA43151.2    APCN01000888    AXCM01006747    AXCN02000267    AJ439060    CAD27758.1    GGFK01001312    MBW34633.1    GGFK01001212    MBW34533.1    GGFJ01002077    MBW51218.1    GGFM01000527    MBW21278.1    GGFM01000600    MBW21351.1    ADMH02001150    ETN63909.1    KA646853    AFP61482.1    CVRI01000006    CRK88011.1    GEBQ01024009    GEBQ01003411    JAT15968.1    JAT36566.1    JXJN01015358    GEBQ01009678    GEBQ01002003    JAT30299.1    JAT37974.1    GDAI01000904    JAI16699.1    UFQS01000635    UFQT01000635    SSX05612.1    SSX25971.1    SSX05611.1    SSX25970.1    GFDG01002067    JAV16732.1    GFDG01002069    JAV16730.1    DS231859    EDS39016.1    CCAG010019856    CH964232    EDW80572.1    GAMC01006625    JAB99930.1    CH916369    EDV93299.1    GDHF01029529    GDHF01021876    JAI22785.1    JAI30438.1    CM000160    EDW95904.1    AF132183    AE014297    AAD34771.1    AAF55552.2    CH902617    EDV42677.1    KPU79847.1    GAKP01016222    JAC42730.1    CH480820    EDW54647.1    GBXI01008638    JAD05654.1    CH479179    EDW24803.1    JR053567    AEY61965.1    CM000070    EAL27684.1    AAZX01007551    CH940652    EDW59356.1    KRF78813.1    KZ288223    PBC31979.1    KQ414710    KOC62988.1    CP012526    ALC46094.1    NEVH01002707    PNF41457.1    CM000364    EDX12446.1    GBYB01003575    JAG73342.1    OUUW01000013    SPP88009.1    KQ971311    EEZ99071.2    KQ977935    KYM98717.1    AJVK01026954    JRES01000835    KNC27927.1    GEZM01101880    GEZM01101878    JAV52238.1    GEZM01101879    JAV52239.1    CH933806    EDW14441.1    KRG01017.1    GFXV01004235    MBW16040.1    KK852470    KDR23260.1    KQ780345    OAD51949.1    KQ976467    KYM84195.1    GL771642    EFZ09639.1    GL446946    EFN87050.1    GDHF01016550    JAI35764.1    ODYU01008382    SOQ51925.1    KQ981905    KYN33595.1    KQ980713    KYN14244.1    KB631625    ERL84786.1    APGK01052546    KB741213    ENN72620.1    KK107589    QOIP01000001    EZA48636.1    RLU27564.1    KQ435724    KOX78327.1    ENN72621.1    ABLF02024323    JRES01000067    KNC34409.1    GDKW01000421    JAI56174.1    JXJN01007702   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000069940    UP000008820    + More
UP000075903    UP000075902    UP000007062    UP000076407    UP000075882    UP000075920    UP000075840    UP000075883    UP000075886    UP000075885    UP000075884    UP000076408    UP000075880    UP000069272    UP000000673    UP000095301    UP000095300    UP000183832    UP000092445    UP000092460    UP000078200    UP000002320    UP000092444    UP000005203    UP000007798    UP000192221    UP000001070    UP000002282    UP000000803    UP000007801    UP000001292    UP000008744    UP000001819    UP000002358    UP000008792    UP000242457    UP000053825    UP000092553    UP000235965    UP000000304    UP000268350    UP000007266    UP000078542    UP000092462    UP000037069    UP000009192    UP000027135    UP000078540    UP000008237    UP000078541    UP000078492    UP000030742    UP000019118    UP000053097    UP000279307    UP000053105    UP000007819   

PRIDE

H9IYU7    Q9VE75   

Pfam

PF01496   V_ATPase_I

Interpro

IPR026028   V-type_ATPase_116kDa_su_euka        + More
IPR002490   V-ATPase_116kDa_su       

ProteinModelPortal

H9IYU7   A0A194QD04   A0A1E1WPT2   A0A1B1UZP4   A0A194RMC5   A0A212ESI2   + More
S4PLD6   U5EY09   A0A1Q3FCP1   A0A1L8DEM8   A0A1L8DEX4   A0A023EW58   Q16HE2   A0A182USZ7   A0A182UDQ6   Q7PKS7   A0A182WSF2   A0A182L9N2   A0A182VZ95   A0A2C9GQN9   A0A182R647   A0A182M9P0   A0A182QWU8   A0A182PGR3   Q8T5K2   A0A182NS68   A0A182YAM6   A0A182IX69   A0A2M4A1G6   A0A2M4A171   A0A2M4BEH6   A0A182F7K3   A0A2M3YYH4   A0A2M3YYN2   W5JMD3   T1PG42   A0A1I8NRD1   A0A1J1HJB8   A0A1A9ZXN1   A0A1B6MKV2   A0A1B0BJB3   A0A1B6MPW5   A0A1A9VER2   A0A0K8TQR7   A0A336KNK4   A0A336M7G7   A0A1L8EDJ5   A0A1L8EDB7   B0W8G6   A0A1B0F9Q1   A0A087ZUG7   B4N9D9   A0A1W4U7R6   W8BF11   B4JF18   A0A0K8UV85   B4PLX2   Q9VE75   B3LW99   A0A034VLS7   B4I290   A0A0A1X2U8   B4G5D7   V9ILL6   Q299L9   K7J2E3   B4M3Z5   A0A2A3ELE4   A0A0L7QWI4   A0A0M5J4P9   A0A2J7RKU2   B4QUE6   A0A0C9R6G2   A0A3B0KN56   D6WCX7   A0A195CD36   A0A1B0D7J1   A0A0L0C6R8   A0A1Y1JVN1   A0A1Y1JSJ5   B4K928   A0A2H8TPX0   A0A067RRK3   A0A310S7A1   A0A195BIS9   E9JC15   E2BB77   A0A0K8V9Z6   A0A2H1WFR4   A0A195EZ62   A0A195DP30   U4U2F9   N6TTR3   A0A026VYX4   A0A0M9A6N9   N6TW70   J9JQN3   A0A0L0CSP3   A0A0P4VSQ7   A0A1B0B2T6  

PDB

6O7T     E-value=5.47325e-162,     Score=1468

KEGG

101742516    K02154 V-type H+-transporting ATPase subunit a | (RefSeq) V-type proton ATPase 116 kDa subunit a iso

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)

GO

GO:0000220   GO:0015991   GO:0015078   GO:0016021   GO:0051117   GO:0016471   GO:0046961   GO:0007035   GO:0005886   GO:0033179   GO:0033181   GO:0006355   GO:0003677   GO:0001664   GO:0005525   GO:0016491   GO:0003824  

PANTHER

PTHR11629  

Length:

838

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

167.11664

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01083

outside

1  -  403

TMhelix

404  -  426

inside

427  -  438

TMhelix

439  -  461

outside

462  -  533

TMhelix

534  -  556

inside

557  -  560

TMhelix

561  -  583

outside

584  -  597

TMhelix

598  -  620

inside

621  -  640

TMhelix

641  -  663

outside

664  -  767

TMhelix

768  -  790

inside

791  -  838

 

 

Pi

252.043429

Theta

174.439921

Tajima's D

1.553286

CLR

0.443694

CSRT

0.79726013699315

Interpretation

Uncertain